WO2004030730A3 - Medication delivery pen - Google Patents

Medication delivery pen Download PDF

Info

Publication number
WO2004030730A3
WO2004030730A3 PCT/US2003/031066 US0331066W WO2004030730A3 WO 2004030730 A3 WO2004030730 A3 WO 2004030730A3 US 0331066 W US0331066 W US 0331066W WO 2004030730 A3 WO2004030730 A3 WO 2004030730A3
Authority
WO
WIPO (PCT)
Prior art keywords
lead screw
medication
delivery pen
medication delivery
reset ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/031066
Other languages
French (fr)
Other versions
WO2004030730A2 (en
Inventor
Antonio Bendek
Lucio Giambattista
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Priority to DE60308042T priority Critical patent/DE60308042T2/en
Priority to JP2004541985A priority patent/JP4741234B2/en
Priority to AU2003275353A priority patent/AU2003275353A1/en
Priority to EP03759629A priority patent/EP1545663B1/en
Publication of WO2004030730A2 publication Critical patent/WO2004030730A2/en
Publication of WO2004030730A3 publication Critical patent/WO2004030730A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/3155Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
    • A61M5/31551Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • A61M5/31541Means preventing setting of a dose beyond the amount remaining in the cartridge
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31583Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
    • A61M5/31585Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403Ampoule inserted into the ampoule holder
    • A61M2005/2407Ampoule inserted into the ampoule holder from the rear
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485Ampoule holder connected to rest of syringe
    • A61M2005/2488Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/581Means for facilitating use, e.g. by people with impaired vision by audible feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/58Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/583Means for facilitating use, e.g. by people with impaired vision by visual feedback
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/24Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31535Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31556Accuracy improving means
    • A61M5/31558Accuracy improving means using scaling up or down transmissions, e.g. gearbox
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31533Dosing mechanisms, i.e. setting a dose
    • A61M5/31545Setting modes for dosing
    • A61M5/31548Mechanically operated dose setting member
    • A61M5/31561Mechanically operated dose setting member using freely adjustable volume steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159Dose expelling manners
    • A61M5/31593Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A medication delivery pen (10) is provided having a lead screw (26) with an enlarged portion (88) at a first end thereof and an end longitudinally opposite the first end in contacting engagement with a plunger (36) of a medication cartridge (30). The lead screw (26) is selectively axially displaceable by a user when selectively administering a predetermined dosage amount of medication for injection into a patient. The medication delivery pen (10) also includes a driver (24) coaxially disposed about the lead screw (26); and, a reset ring (20) non-rotatably disposed on the driver (24) and axially slidable thereon and therealong. The reset ring (20) is axially movable with respect to the driver (24) when a dosage amount is set by a user of the medication delivery pen (10). The reset ring (20) engages the enlarged portion (88) of the lead screw (26) upon a predetermined extent of relative axial movement between the reset ring (20) and the lead screw (26). With this arrangement, the reset ring (20) advantageously prevents setting a dose on a medication delivery pen (20) that is greater than the medication which is available.
PCT/US2003/031066 2002-10-01 2003-10-01 Medication delivery pen Ceased WO2004030730A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE60308042T DE60308042T2 (en) 2002-10-01 2003-10-01 PEN DRY MEDICATION SYRINGE
JP2004541985A JP4741234B2 (en) 2002-10-01 2003-10-01 Drug administration pen
AU2003275353A AU2003275353A1 (en) 2002-10-01 2003-10-01 Medication delivery pen
EP03759629A EP1545663B1 (en) 2002-10-01 2003-10-01 Medication delivery pen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41519802P 2002-10-01 2002-10-01
US60/415,198 2002-10-01

Publications (2)

Publication Number Publication Date
WO2004030730A2 WO2004030730A2 (en) 2004-04-15
WO2004030730A3 true WO2004030730A3 (en) 2004-05-27

Family

ID=32069826

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/031066 Ceased WO2004030730A2 (en) 2002-10-01 2003-10-01 Medication delivery pen

Country Status (9)

Country Link
US (1) US7169132B2 (en)
EP (1) EP1545663B1 (en)
JP (1) JP4741234B2 (en)
CN (1) CN100431631C (en)
AT (1) ATE337810T1 (en)
AU (1) AU2003275353A1 (en)
DE (1) DE60308042T2 (en)
ES (1) ES2270096T3 (en)
WO (1) WO2004030730A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11020534B2 (en) 2019-03-25 2021-06-01 Shaily Engineering Plastics Limited Fixed dose injector pen

Families Citing this family (142)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3993169B2 (en) 2002-02-11 2007-10-17 アンタレス・ファーマ・インコーポレーテッド Intradermal syringe
GB0304823D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
EP2210634A1 (en) 2009-01-22 2010-07-28 Sanofi-Aventis Deutschland GmbH Drug delivery device dose setting mechanism
GB0304822D0 (en) 2003-03-03 2003-04-09 Dca Internat Ltd Improvements in and relating to a pen-type injector
US6932794B2 (en) * 2003-04-03 2005-08-23 Becton, Dickinson And Company Medication delivery pen
AU2004266131C1 (en) 2003-08-12 2010-12-16 Eli Lilly And Company Medication dispensing apparatus with triple screw threads for mechanical advantage
DE202004006611U1 (en) * 2004-04-23 2005-08-25 Tecpharma Licensing Ag Injection device for administering an injectable product with secured dosing device
NZ554384A (en) 2004-10-04 2010-04-30 Sanofi Aventis Deutschland Drive mechanism for drug delivery device
DE102005001159A1 (en) * 2005-01-10 2006-07-20 Tecpharma Licensing Ag Dosing device for an injection device with translation
JP5216328B2 (en) 2005-01-24 2013-06-19 アンタレス ファーマ インコーポレイテッド Pre-filled needle assist syringe jet injector
DE102005023823B4 (en) 2005-05-24 2022-11-17 Tecpharma Licensing Ag Dosing device for an injection device and injection device with such a dosing device
WO2007017053A1 (en) 2005-07-27 2007-02-15 Novo Nordisk A/S Syringe device with a dose limiting mechanism and an additional safety mechanism
ATE499962T1 (en) 2005-07-27 2011-03-15 Novo Nordisk As DOSE MECHANISM FOR AN INJECTION DEVICE FOR LIMITING A DOSE SETTING ACCORDING TO THE REMAINING AMOUNT OF DRUG
US9144648B2 (en) 2006-05-03 2015-09-29 Antares Pharma, Inc. Injector with adjustable dosing
WO2007131013A1 (en) 2006-05-03 2007-11-15 Antares Pharma, Inc. Two-stage reconstituting injector
ES2425579T3 (en) 2006-05-25 2013-10-16 Bayer Healthcare, Llc Reconstitution device
HUE060243T2 (en) 2006-09-15 2023-02-28 Ypsomed Ag Injection device comprising an improved delivery element
DE102007018696A1 (en) 2007-04-18 2008-10-23 Sanofi-Aventis Deutschland Gmbh Injection device for dispensing a medicament
US9205193B2 (en) * 2007-06-12 2015-12-08 Peter V. Boesen Self-contained medication injection system and method
US8771237B2 (en) * 2007-12-20 2014-07-08 Novo Nordisk A/S Injection device for delivering a fixed dose of liquid drug
EP2268342B1 (en) 2008-03-10 2015-09-16 Antares Pharma, Inc. Injector safety device
RS52103B (en) 2008-05-02 2012-06-30 Sanofi-Aventis Deutschland Gmbh MEDICINE
WO2009150071A1 (en) * 2008-06-11 2009-12-17 Shl Group Ab Medicament delivery device
US9345835B2 (en) * 2008-07-18 2016-05-24 Becton, Dickinson And Company Cartridge stopper for an intradermal delivery system
EP3581224A1 (en) 2008-08-05 2019-12-18 Antares Pharma, Inc. Multiple dosage injector
DK2337596T3 (en) 2008-09-18 2020-02-10 Becton Dickinson Co Medical injector with garbage stamp
DK2468344T3 (en) 2008-10-13 2013-12-09 Sanofi Aventis Deutschland Drug delivery device and method for manufacturing drug delivery device
CA2746160C (en) 2008-12-09 2017-02-14 Becton, Dickinson And Company Multi-stroke delivery pumping mechanism for a drug delivery device for high pressure injections
US9446200B2 (en) 2008-12-09 2016-09-20 Becton, Dickinson And Company Lever and gear force multiplier medication delivery system for high pressure injection system
CA2746164C (en) 2008-12-09 2019-08-13 Becton, Dickinson And Company Open and closed valve medication delivery system for high pressure injections
JP2012511391A (en) 2008-12-09 2012-05-24 ベクトン・ディキンソン・アンド・カンパニー Two-load medicine delivery device for high-pressure injection
EP2196233A1 (en) 2008-12-12 2010-06-16 Sanofi-Aventis Deutschland GmbH Resettable drive mechanism for a medication delivery device and medication delivery device
WO2010069943A1 (en) * 2008-12-16 2010-06-24 Bracco Research Sa Device for bolus administration of contrast agent
JP5711155B2 (en) 2009-02-27 2015-04-30 ライフスキャン・インコーポレイテッドLifescan,Inc. Medical module for drug delivery pen
CN102612381B (en) 2009-03-20 2015-09-09 安塔瑞斯制药公司 Hazardous Reagent Injection System
EP2415041B1 (en) 2009-03-31 2018-11-21 Sanofi-Aventis Deutschland GmbH Method for manufacturing a drug delivery device body using an adhesive and drug delivery device body
WO2010112565A1 (en) 2009-03-31 2010-10-07 Sanofi-Aventis Deutschland Gmbh Dose button for a drug delivery device and method for manufacturing a dose button
CA2756962A1 (en) 2009-03-31 2010-10-14 Sanofi-Aventis Deutschland Gmbh Pen cap
WO2010115818A1 (en) 2009-03-31 2010-10-14 Sanofi-Aventis Deutschland Gmbh Drug delivery device
BRPI1016143A2 (en) 2009-04-30 2016-04-19 Sanofi Aventis Deutschland axially adjustable piston rod connection for triggering mechanism of a drug delivery device
US9457150B2 (en) * 2009-06-01 2016-10-04 Sanofi-Aventis Deutschland Gmbh Biasing mechanism for a drug delivery device
US9108007B2 (en) * 2009-06-01 2015-08-18 Sanofi-Aventis Deutschland Gmbh Spindle and bearing combination and drug delivery device
US9623187B2 (en) * 2009-06-01 2017-04-18 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US8257319B2 (en) 2009-06-01 2012-09-04 Sanofi-Aventis Deutschland Gmbh Drug delivery device inner housing having helical spline
US8672896B2 (en) * 2009-06-01 2014-03-18 Sanofi-Aventis Deutschland Gmbh Inner housing for a drug delivery device
US9199040B2 (en) 2009-06-01 2015-12-01 Sanofi-Aventis Deutschland Gmbh Drug delivery device last dose lock-out mechanism
US8728043B2 (en) * 2009-06-01 2014-05-20 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device
US9238106B2 (en) * 2009-06-01 2016-01-19 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US8974423B2 (en) * 2009-06-01 2015-03-10 Sanofi-Aventis Deutschland Gmbh Resettable drug delivery device
US8585656B2 (en) * 2009-06-01 2013-11-19 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
US10034982B2 (en) * 2009-06-01 2018-07-31 Sanofi-Aventis Deutschland Gmbh Spindle for a drug delivery device
US9345840B2 (en) * 2009-06-01 2016-05-24 Sanofi-Aventis Deutschland Gmbh Drug delivery dose setting mechanism with variable maximum dose
US9125994B2 (en) * 2009-06-01 2015-09-08 Sanofi—Aventis Deutschland GmbH Drug delivery device with dose dial sleeve rotational stop
US9463283B2 (en) * 2009-06-01 2016-10-11 Sanofi-Aventis Deutschland Gmbh Dosing mechanism for a drug deliver device
US20110015576A1 (en) * 2009-06-01 2011-01-20 Sanofi-Aventis Deutschland Gmbh Medicament identification system for multi-dose injection devices
US9950116B2 (en) 2009-06-01 2018-04-24 Sanofi-Aventis Deutschland Gmbh Dose setting mechanism for priming a drug delivery device
AR076722A1 (en) 2009-06-02 2011-06-29 Sanofi Aventis Deutschland SET FOR A DEVICE FOR THE DELIVERY OF PHARMACOS AND DEVICE FOR THE DELIVERY OF PHARMACOS
EP2482901B1 (en) 2009-09-30 2019-10-23 Sanofi-Aventis Deutschland GmbH Injection device
US20120283652A1 (en) * 2009-09-30 2012-11-08 Sanofi-Aventis Deutschland Gmbh Assembly and Piston Rod for a Drug Delivery Device
GB0918145D0 (en) 2009-10-16 2009-12-02 Owen Mumford Ltd Injector apparatus
JP5777629B2 (en) 2009-11-03 2015-09-09 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Assembly for drug delivery device and drug delivery device
ES2814256T3 (en) * 2009-12-01 2021-03-26 Becton Dickinson Co Injection pen with automatic reverse and last dose control
WO2011068544A1 (en) 2009-12-04 2011-06-09 Becton, Dickinson And Company Cartridge for containing and dispensing a medicament
FR2953415B1 (en) * 2009-12-09 2012-12-28 Primequal Sa EJECTION DEVICE FOR EJECTING LOW DOSES
EP2536456B1 (en) * 2010-02-17 2021-04-28 Sanofi-Aventis Deutschland GmbH Automatic injection device with torsional spring
IT1398501B1 (en) * 2010-03-10 2013-03-01 Menarini Int Operations Lu Sa AUTOINECTOR DEVICE FOR TWO DRUG DOSES
WO2012017035A1 (en) 2010-08-06 2012-02-09 Sanofi-Aventis Deutschland Gmbh Cartridge holder and method for assembling a cartridge unit for a drug delivery device
AR083378A1 (en) * 2010-10-13 2013-02-21 Sanofi Aventis Deutschland MECHANISM OF DOSE ESTABLISHMENT AND METHOD FOR ESTABLISHING A DOSE
WO2012068432A1 (en) 2010-11-19 2012-05-24 Msd Consumer Care, Inc. Click pen applicator device and method of using same
AU2011347652B2 (en) 2010-12-21 2015-03-26 Sanofi-Aventis Deutschland Gmbh Injection device with dose setting mechanism having maximum dose stop
EP2670459B1 (en) * 2011-01-31 2016-11-09 SHL Group AB Coupling arrangement
TWI538707B (en) 2011-05-06 2016-06-21 賽諾菲阿凡提斯德意志有限公司 Drug delivery device and cartridge holder for a drug delivery device
JP6057991B2 (en) * 2011-06-17 2017-01-11 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Cartridge holder assembly for drug delivery device
US8496619B2 (en) 2011-07-15 2013-07-30 Antares Pharma, Inc. Injection device with cammed ram assembly
US9220660B2 (en) 2011-07-15 2015-12-29 Antares Pharma, Inc. Liquid-transfer adapter beveled spike
CN103732274B (en) * 2011-08-05 2017-07-21 尤尼特拉克特注射器公司 Two-chamber mixing arrangement for syringe
US9821118B2 (en) 2011-09-02 2017-11-21 Unl Holdings Llc Automatic reconstitution for dual chamber syringe
ES2675035T3 (en) 2011-10-14 2018-07-05 Amgen, Inc Injector and assembly method
CH703993A2 (en) 2012-02-09 2012-03-15 Tecpharma Licensing Ag Injection device for dispensing fluid product, has bearing coupling surfaces that are formed in coupling mechanism to produce acoustic/tactile signals corresponding to adjusted or corrected dose during dose dispensing process
WO2013134244A2 (en) 2012-03-06 2013-09-12 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
EP2825229B1 (en) 2012-03-16 2020-12-30 SHL Medical AG Medicament delivery device
AU2013245106B2 (en) 2012-04-05 2017-07-27 Sanofi-Aventis Deutschland Gmbh Pen -type injector with window element
KR20150011346A (en) 2012-04-06 2015-01-30 안타레스 팔마, 인코퍼레이티드 Needle assisted jet injection administration of testosterone compositions
USD680643S1 (en) 2012-04-13 2013-04-23 Becton, Dickinson And Company Self injection device window
USD696397S1 (en) 2012-04-13 2013-12-24 Becton, Dickinson And Company Autoinjector
USD708317S1 (en) 2012-04-13 2014-07-01 Becton, Dickinson And Company Autoinjector
USD740937S1 (en) 2012-04-13 2015-10-13 Becton Dickinson And Company Self injection device window
USD696774S1 (en) 2012-04-13 2013-12-31 Becton, Dickinson And Company Autoinjector
USD696772S1 (en) 2012-04-13 2013-12-31 Becton, Dickinson And Company Autoinjector
USD696771S1 (en) 2012-04-13 2013-12-31 Becton, Dickinson And Company Self injection device
USD703314S1 (en) 2012-04-13 2014-04-22 Becton, Dickinson And Company Self injection device
USD697205S1 (en) 2012-04-13 2014-01-07 Becton, Dickinson And Company Autoinjector
USD696775S1 (en) 2012-04-13 2013-12-31 Becton, Dickinson And Company Autoinjector
USD696770S1 (en) 2012-04-13 2013-12-31 Becton, Dickinson And Company Autoinjector
USD696773S1 (en) 2012-04-13 2013-12-31 Becton, Dickinson And Company Self injection device
EP2838591B1 (en) 2012-04-19 2022-11-16 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device and drug delivery device
US9149585B2 (en) 2012-04-20 2015-10-06 Cook Medical Technologies Llc Multi-needle injection device
US9364610B2 (en) 2012-05-07 2016-06-14 Antares Pharma, Inc. Injection device with cammed ram assembly
CH706567A2 (en) 2012-05-16 2013-11-29 Tecpharma Licensing Ag Improved device to set a dose a limiting mechanism for an apparatus for administering a product.
EP2854909B1 (en) 2012-05-30 2020-07-15 Sanofi-Aventis Deutschland GmbH Bearing for a piston rod body for a drug delivery device, a piston rod arrangement and a piston rod body
CN102716529B (en) * 2012-06-29 2014-02-19 北京甘甘科技有限公司 Pen injector
EP4501376A3 (en) 2012-08-08 2025-04-16 Sanofi-Aventis Deutschland GmbH Drug delivery device with tamper-evident closure
AR092276A1 (en) 2012-08-31 2015-04-08 Sanofi Aventis Deutschland FARMACOS ADMINISTRATION DEVICE
AU2013310949A1 (en) 2012-08-31 2015-03-12 Sanofi-Aventis Deutschland Gmbh Drug delivery device
US10780231B2 (en) 2012-09-11 2020-09-22 Sanofi-Aventis Deutschland Gmbh Drive mechanism for a drug delivery device and drug delivery device
USD688793S1 (en) 2012-10-05 2013-08-27 Becton, Dickinson And Company Self-injection device
USD688792S1 (en) 2012-10-05 2013-08-27 Becton, Dickinson And Company Self-injection device
USD688790S1 (en) 2012-10-05 2013-08-27 Becton, Dickinson And Company Self-injection device
USD688791S1 (en) 2012-10-05 2013-08-27 Becton, Dickinson And Company Self-injection device
WO2014085118A1 (en) 2012-11-30 2014-06-05 Unitract Syringe Pty Ltd Combination plunger device for a dual chamber mixing syringe
ES2969984T3 (en) 2013-02-11 2024-05-23 Antares Pharma Inc Needle-assisted jet injection device having reduced firing force
TWI653069B (en) 2013-03-11 2019-03-11 德商賽諾菲阿凡提斯德意志有限公司 "piston rod and drug delivery device comprising the piston rod"
JP6030803B2 (en) 2013-03-11 2016-11-24 アンタレス・ファーマ・インコーポレーテッド Dose syringe with pinion system
WO2014165136A1 (en) 2013-03-12 2014-10-09 Antares Pharma, Inc. Constant volume prefilled syringes and kits thereof
EP3881880B1 (en) 2013-03-13 2025-04-02 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device comprising a feedback feature
US10300207B2 (en) * 2013-03-13 2019-05-28 Antares Pharma, Inc. Multiple dosage injector with rotating screw dosage system
US10406293B2 (en) 2013-03-13 2019-09-10 Sanofi-Aventis Deutschland Gmbh Assembly for a drug delivery device comprising a feedback feature
IL292270B2 (en) 2013-03-22 2024-04-01 Amgen Inc Injector and assembly method
JP6417393B2 (en) 2013-04-10 2018-11-07 サノフイSanofi Drive assembly for a drug delivery device
MX2015015804A (en) 2013-05-16 2016-06-21 Sanofi Aventis Deutschland Mechanism for a drug delivery device.
DK3003432T3 (en) 2013-05-27 2020-03-30 Sanofi Aventis Deutschland DRIVE DEVICE FOR PHARMACEUTICAL ADMINISTRATION AND PHARMACEUTICAL ADMINISTRATION DEVICE
CA2914028A1 (en) 2013-06-04 2014-12-11 Unitract Syringe Pty Ltd Actuation mechanisms for dual chamber mixing syringes
EP3038676A1 (en) 2013-08-29 2016-07-06 Sanofi-Aventis Deutschland GmbH Housing and cap for an injection device made of an outer metal part and an inner plastic part
US10617829B2 (en) 2013-08-29 2020-04-14 Sanofi-Aventis Deutschland Gmbh Cap assembly for a drug delivery device and drug delivery device
PL3038678T3 (en) 2013-08-29 2020-06-29 Sanofi-Aventis Deutschland Gmbh Cap for a drug delivery device
US10238807B2 (en) 2013-09-03 2019-03-26 Sanofi Drive mechanism and injection device herewith
BR112016005547B1 (en) 2013-09-23 2022-02-01 Sanofi-Aventis Deutschland Gmbh SET FOR A DRUG DELIVERY DEVICE AND DRUG DELIVERY DEVICE
MX373358B (en) 2013-10-24 2020-07-06 Amgen Inc INJECTOR AND MOUNTING METHOD.
EP3082910B1 (en) 2013-12-20 2020-03-04 Sanofi-Aventis Deutschland GmbH Assembly for a drug delivery device and drug delivery device
US10004845B2 (en) 2014-04-18 2018-06-26 Becton, Dickinson And Company Split piston metering pump
US9416775B2 (en) 2014-07-02 2016-08-16 Becton, Dickinson And Company Internal cam metering pump
JP6453080B2 (en) * 2015-01-09 2019-01-16 三菱鉛筆株式会社 Chemical supply device
EP3064239A1 (en) * 2015-03-05 2016-09-07 Carebay Europe Ltd. Medicament delivery device with information provider system
KR102546986B1 (en) 2015-03-23 2023-06-26 사노피-아벤티스 도이칠란트 게엠베하 Housing for injection device and interconnection of housing components
CN105749383B (en) 2016-04-21 2017-03-08 北京甘甘科技有限公司 Pre-filled pen-type injector
EP3603703A1 (en) 2018-07-30 2020-02-05 Tecpharma Licensing AG Alternative device for adjusting a dosage with a limiting mechanism for a device for administering a product
DK3843818T3 (en) * 2018-08-29 2022-08-29 Sanofi Aventis Deutschland IMPROVED DOSING MECHANISM AND INJECTION DEVICE
US11911499B2 (en) 2019-11-07 2024-02-27 Resurge Therapeutics, Inc. System and method for prostate treatment
US11974979B2 (en) 2022-01-29 2024-05-07 Resurge Therapeutics, Inc. Treatments for benign prostatic hyperplasia
US11957654B2 (en) 2022-01-29 2024-04-16 Resurge Therapeutics, Inc. Treating benign prostatic hyperplasia
CN114681718B (en) * 2022-03-30 2024-03-19 宁波睿爱产品设计有限公司 Multiple quantitative injector
CN118617073B (en) * 2024-06-13 2025-09-09 迈得医疗工业设备股份有限公司 production equipment

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0937476A2 (en) * 1998-02-23 1999-08-25 Becton, Dickinson and Company Low-cost medication delivery pen
US6221046B1 (en) * 1995-03-07 2001-04-24 Eli Lilly And Company Recyclable medication dispensing device

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8713810D0 (en) * 1987-06-12 1987-07-15 Hypoguard Uk Ltd Measured dose dispensing device
JPH04256757A (en) * 1991-02-07 1992-09-11 Terumo Corp Quantitative dispenser
JPH04256758A (en) * 1991-02-07 1992-09-11 Terumo Corp Quantitative dispenser
DE4112259A1 (en) * 1991-04-15 1992-10-22 Medico Dev Investment Co INJECTION DEVICE
US5279585A (en) * 1992-02-04 1994-01-18 Becton, Dickinson And Company Medication delivery pen having improved dose delivery features
US5320609A (en) * 1992-12-07 1994-06-14 Habley Medical Technology Corporation Automatic pharmaceutical dispensing syringe
US5725508A (en) * 1994-06-22 1998-03-10 Becton Dickinson And Company Quick connect medication delivery pen
US6221053B1 (en) * 1998-02-20 2001-04-24 Becton, Dickinson And Company Multi-featured medication delivery pen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221046B1 (en) * 1995-03-07 2001-04-24 Eli Lilly And Company Recyclable medication dispensing device
EP0937476A2 (en) * 1998-02-23 1999-08-25 Becton, Dickinson and Company Low-cost medication delivery pen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11020534B2 (en) 2019-03-25 2021-06-01 Shaily Engineering Plastics Limited Fixed dose injector pen

Also Published As

Publication number Publication date
EP1545663A2 (en) 2005-06-29
CN100431631C (en) 2008-11-12
DE60308042D1 (en) 2006-10-12
JP4741234B2 (en) 2011-08-03
US7169132B2 (en) 2007-01-30
AU2003275353A1 (en) 2004-04-23
US20040127858A1 (en) 2004-07-01
ES2270096T3 (en) 2007-04-01
ATE337810T1 (en) 2006-09-15
EP1545663B1 (en) 2006-08-30
DE60308042T2 (en) 2007-04-12
CN1723054A (en) 2006-01-18
WO2004030730A2 (en) 2004-04-15
JP2006501036A (en) 2006-01-12

Similar Documents

Publication Publication Date Title
WO2004030730A3 (en) Medication delivery pen
CN100502963C (en) Injection device
US9457156B2 (en) Injection device comprising a needle protecting sleeve
US8574199B2 (en) Coupling for injection devices
EP2475411B1 (en) Drive mechanism for drug delivery device
EP2686042B1 (en) End of injection indicator for injection pen
EP1690561A3 (en) Injection device with a dose application counter
US9132240B2 (en) Injection pen for intradermal medication injection
WO2002005876A3 (en) A liquid medication delivery device and a method of delivering an intended dose
AU3156393A (en) An automatic pen-shaped syringe
DE69626839D1 (en) PEN-LIKE SYRINGE WITH DOSING CLUTCH ACTUATED BY A CAP
WO2004093940A3 (en) Medication delivery pen
ATE506981T1 (en) MEDICAL INJECTION DEVICE
WO2007027204A3 (en) Injector device with force lock-out and injection rate limiting mechanisms
US20070197975A1 (en) Dose Metering Mechanism with Sequence Control
EP0904792A3 (en) Syringe holder with integral dose divider
PT1603610E (en) Pen-type injector with dose dial sleeve
ATE299728T1 (en) DOSAGE LIMITER
WO2006020756A3 (en) Step by step botox injector
GB0304823D0 (en) Improvements in and relating to a pen-type injector
WO1992019296A3 (en) System and method for rapid vascular drug delivery
WO2004078226A3 (en) Improvements in and relating to drive mechanisms suitable for use in drug delivery devices
KR20030065489A (en) Pen device for administration of parathyroid hormone
CA2087944A1 (en) Reusable medication delivery pen
WO2008057976A3 (en) Multiple dose syringes

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004541985

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2003759629

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 1683/DELNP/2005

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 20038A34490

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2003759629

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2003759629

Country of ref document: EP