WO2004030730A3 - Medication delivery pen - Google Patents
Medication delivery pen Download PDFInfo
- Publication number
- WO2004030730A3 WO2004030730A3 PCT/US2003/031066 US0331066W WO2004030730A3 WO 2004030730 A3 WO2004030730 A3 WO 2004030730A3 US 0331066 W US0331066 W US 0331066W WO 2004030730 A3 WO2004030730 A3 WO 2004030730A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- lead screw
- medication
- delivery pen
- medication delivery
- reset ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2485—Ampoule holder connected to rest of syringe
- A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/583—Means for facilitating use, e.g. by people with impaired vision by visual feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31556—Accuracy improving means
- A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31561—Mechanically operated dose setting member using freely adjustable volume steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- External Artificial Organs (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE60308042T DE60308042T2 (en) | 2002-10-01 | 2003-10-01 | PEN DRY MEDICATION SYRINGE |
| JP2004541985A JP4741234B2 (en) | 2002-10-01 | 2003-10-01 | Drug administration pen |
| AU2003275353A AU2003275353A1 (en) | 2002-10-01 | 2003-10-01 | Medication delivery pen |
| EP03759629A EP1545663B1 (en) | 2002-10-01 | 2003-10-01 | Medication delivery pen |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41519802P | 2002-10-01 | 2002-10-01 | |
| US60/415,198 | 2002-10-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004030730A2 WO2004030730A2 (en) | 2004-04-15 |
| WO2004030730A3 true WO2004030730A3 (en) | 2004-05-27 |
Family
ID=32069826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2003/031066 Ceased WO2004030730A2 (en) | 2002-10-01 | 2003-10-01 | Medication delivery pen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7169132B2 (en) |
| EP (1) | EP1545663B1 (en) |
| JP (1) | JP4741234B2 (en) |
| CN (1) | CN100431631C (en) |
| AT (1) | ATE337810T1 (en) |
| AU (1) | AU2003275353A1 (en) |
| DE (1) | DE60308042T2 (en) |
| ES (1) | ES2270096T3 (en) |
| WO (1) | WO2004030730A2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11020534B2 (en) | 2019-03-25 | 2021-06-01 | Shaily Engineering Plastics Limited | Fixed dose injector pen |
Families Citing this family (142)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3993169B2 (en) | 2002-02-11 | 2007-10-17 | アンタレス・ファーマ・インコーポレーテッド | Intradermal syringe |
| GB0304823D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| EP2210634A1 (en) | 2009-01-22 | 2010-07-28 | Sanofi-Aventis Deutschland GmbH | Drug delivery device dose setting mechanism |
| GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
| US6932794B2 (en) * | 2003-04-03 | 2005-08-23 | Becton, Dickinson And Company | Medication delivery pen |
| AU2004266131C1 (en) | 2003-08-12 | 2010-12-16 | Eli Lilly And Company | Medication dispensing apparatus with triple screw threads for mechanical advantage |
| DE202004006611U1 (en) * | 2004-04-23 | 2005-08-25 | Tecpharma Licensing Ag | Injection device for administering an injectable product with secured dosing device |
| NZ554384A (en) | 2004-10-04 | 2010-04-30 | Sanofi Aventis Deutschland | Drive mechanism for drug delivery device |
| DE102005001159A1 (en) * | 2005-01-10 | 2006-07-20 | Tecpharma Licensing Ag | Dosing device for an injection device with translation |
| JP5216328B2 (en) | 2005-01-24 | 2013-06-19 | アンタレス ファーマ インコーポレイテッド | Pre-filled needle assist syringe jet injector |
| DE102005023823B4 (en) † | 2005-05-24 | 2022-11-17 | Tecpharma Licensing Ag | Dosing device for an injection device and injection device with such a dosing device |
| WO2007017053A1 (en) | 2005-07-27 | 2007-02-15 | Novo Nordisk A/S | Syringe device with a dose limiting mechanism and an additional safety mechanism |
| ATE499962T1 (en) | 2005-07-27 | 2011-03-15 | Novo Nordisk As | DOSE MECHANISM FOR AN INJECTION DEVICE FOR LIMITING A DOSE SETTING ACCORDING TO THE REMAINING AMOUNT OF DRUG |
| US9144648B2 (en) | 2006-05-03 | 2015-09-29 | Antares Pharma, Inc. | Injector with adjustable dosing |
| WO2007131013A1 (en) | 2006-05-03 | 2007-11-15 | Antares Pharma, Inc. | Two-stage reconstituting injector |
| ES2425579T3 (en) | 2006-05-25 | 2013-10-16 | Bayer Healthcare, Llc | Reconstitution device |
| HUE060243T2 (en) | 2006-09-15 | 2023-02-28 | Ypsomed Ag | Injection device comprising an improved delivery element |
| DE102007018696A1 (en) | 2007-04-18 | 2008-10-23 | Sanofi-Aventis Deutschland Gmbh | Injection device for dispensing a medicament |
| US9205193B2 (en) * | 2007-06-12 | 2015-12-08 | Peter V. Boesen | Self-contained medication injection system and method |
| US8771237B2 (en) * | 2007-12-20 | 2014-07-08 | Novo Nordisk A/S | Injection device for delivering a fixed dose of liquid drug |
| EP2268342B1 (en) | 2008-03-10 | 2015-09-16 | Antares Pharma, Inc. | Injector safety device |
| RS52103B (en) | 2008-05-02 | 2012-06-30 | Sanofi-Aventis Deutschland Gmbh | MEDICINE |
| WO2009150071A1 (en) * | 2008-06-11 | 2009-12-17 | Shl Group Ab | Medicament delivery device |
| US9345835B2 (en) * | 2008-07-18 | 2016-05-24 | Becton, Dickinson And Company | Cartridge stopper for an intradermal delivery system |
| EP3581224A1 (en) | 2008-08-05 | 2019-12-18 | Antares Pharma, Inc. | Multiple dosage injector |
| DK2337596T3 (en) | 2008-09-18 | 2020-02-10 | Becton Dickinson Co | Medical injector with garbage stamp |
| DK2468344T3 (en) | 2008-10-13 | 2013-12-09 | Sanofi Aventis Deutschland | Drug delivery device and method for manufacturing drug delivery device |
| CA2746160C (en) | 2008-12-09 | 2017-02-14 | Becton, Dickinson And Company | Multi-stroke delivery pumping mechanism for a drug delivery device for high pressure injections |
| US9446200B2 (en) | 2008-12-09 | 2016-09-20 | Becton, Dickinson And Company | Lever and gear force multiplier medication delivery system for high pressure injection system |
| CA2746164C (en) | 2008-12-09 | 2019-08-13 | Becton, Dickinson And Company | Open and closed valve medication delivery system for high pressure injections |
| JP2012511391A (en) | 2008-12-09 | 2012-05-24 | ベクトン・ディキンソン・アンド・カンパニー | Two-load medicine delivery device for high-pressure injection |
| EP2196233A1 (en) | 2008-12-12 | 2010-06-16 | Sanofi-Aventis Deutschland GmbH | Resettable drive mechanism for a medication delivery device and medication delivery device |
| WO2010069943A1 (en) * | 2008-12-16 | 2010-06-24 | Bracco Research Sa | Device for bolus administration of contrast agent |
| JP5711155B2 (en) | 2009-02-27 | 2015-04-30 | ライフスキャン・インコーポレイテッドLifescan,Inc. | Medical module for drug delivery pen |
| CN102612381B (en) | 2009-03-20 | 2015-09-09 | 安塔瑞斯制药公司 | Hazardous Reagent Injection System |
| EP2415041B1 (en) | 2009-03-31 | 2018-11-21 | Sanofi-Aventis Deutschland GmbH | Method for manufacturing a drug delivery device body using an adhesive and drug delivery device body |
| WO2010112565A1 (en) | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Dose button for a drug delivery device and method for manufacturing a dose button |
| CA2756962A1 (en) | 2009-03-31 | 2010-10-14 | Sanofi-Aventis Deutschland Gmbh | Pen cap |
| WO2010115818A1 (en) | 2009-03-31 | 2010-10-14 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
| BRPI1016143A2 (en) | 2009-04-30 | 2016-04-19 | Sanofi Aventis Deutschland | axially adjustable piston rod connection for triggering mechanism of a drug delivery device |
| US9457150B2 (en) * | 2009-06-01 | 2016-10-04 | Sanofi-Aventis Deutschland Gmbh | Biasing mechanism for a drug delivery device |
| US9108007B2 (en) * | 2009-06-01 | 2015-08-18 | Sanofi-Aventis Deutschland Gmbh | Spindle and bearing combination and drug delivery device |
| US9623187B2 (en) * | 2009-06-01 | 2017-04-18 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
| US8257319B2 (en) | 2009-06-01 | 2012-09-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device inner housing having helical spline |
| US8672896B2 (en) * | 2009-06-01 | 2014-03-18 | Sanofi-Aventis Deutschland Gmbh | Inner housing for a drug delivery device |
| US9199040B2 (en) | 2009-06-01 | 2015-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device last dose lock-out mechanism |
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| US9238106B2 (en) * | 2009-06-01 | 2016-01-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
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| US9345840B2 (en) * | 2009-06-01 | 2016-05-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery dose setting mechanism with variable maximum dose |
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| US9463283B2 (en) * | 2009-06-01 | 2016-10-11 | Sanofi-Aventis Deutschland Gmbh | Dosing mechanism for a drug deliver device |
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| CN103732274B (en) * | 2011-08-05 | 2017-07-21 | 尤尼特拉克特注射器公司 | Two-chamber mixing arrangement for syringe |
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- 2003-10-01 US US10/676,341 patent/US7169132B2/en not_active Expired - Lifetime
- 2003-10-01 EP EP03759629A patent/EP1545663B1/en not_active Expired - Lifetime
- 2003-10-01 ES ES03759629T patent/ES2270096T3/en not_active Expired - Lifetime
- 2003-10-01 DE DE60308042T patent/DE60308042T2/en not_active Expired - Lifetime
- 2003-10-01 JP JP2004541985A patent/JP4741234B2/en not_active Expired - Lifetime
- 2003-10-01 AT AT03759629T patent/ATE337810T1/en not_active IP Right Cessation
- 2003-10-01 CN CNB2003801034490A patent/CN100431631C/en not_active Expired - Lifetime
- 2003-10-01 WO PCT/US2003/031066 patent/WO2004030730A2/en not_active Ceased
- 2003-10-01 AU AU2003275353A patent/AU2003275353A1/en not_active Abandoned
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| US11020534B2 (en) | 2019-03-25 | 2021-06-01 | Shaily Engineering Plastics Limited | Fixed dose injector pen |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1545663A2 (en) | 2005-06-29 |
| CN100431631C (en) | 2008-11-12 |
| DE60308042D1 (en) | 2006-10-12 |
| JP4741234B2 (en) | 2011-08-03 |
| US7169132B2 (en) | 2007-01-30 |
| AU2003275353A1 (en) | 2004-04-23 |
| US20040127858A1 (en) | 2004-07-01 |
| ES2270096T3 (en) | 2007-04-01 |
| ATE337810T1 (en) | 2006-09-15 |
| EP1545663B1 (en) | 2006-08-30 |
| DE60308042T2 (en) | 2007-04-12 |
| CN1723054A (en) | 2006-01-18 |
| WO2004030730A2 (en) | 2004-04-15 |
| JP2006501036A (en) | 2006-01-12 |
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