WO2004047690A3 - Prosthetic spinal disc nucleus with elevated swelling rate - Google Patents

Prosthetic spinal disc nucleus with elevated swelling rate Download PDF

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Publication number
WO2004047690A3
WO2004047690A3 PCT/US2003/037870 US0337870W WO2004047690A3 WO 2004047690 A3 WO2004047690 A3 WO 2004047690A3 US 0337870 W US0337870 W US 0337870W WO 2004047690 A3 WO2004047690 A3 WO 2004047690A3
Authority
WO
WIPO (PCT)
Prior art keywords
swelling rate
spinal disc
disc nucleus
hydrogel
prosthetic spinal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2003/037870
Other languages
French (fr)
Other versions
WO2004047690A8 (en
WO2004047690A2 (en
Inventor
Tara Nicole Sherman
Britt Keenan Norton
Allison C Bain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
RayMedica Inc
Original Assignee
RayMedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RayMedica Inc filed Critical RayMedica Inc
Priority to EP03787185A priority Critical patent/EP1565130A2/en
Priority to AU2003295970A priority patent/AU2003295970A1/en
Publication of WO2004047690A2 publication Critical patent/WO2004047690A2/en
Publication of WO2004047690A3 publication Critical patent/WO2004047690A3/en
Publication of WO2004047690A8 publication Critical patent/WO2004047690A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/441—Joints for the spine, e.g. vertebrae, spinal discs made of inflatable pockets or chambers filled with fluid, e.g. with hydrogel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442—Intervertebral or spinal discs, e.g. resilient
    • A61F2002/444—Intervertebral or spinal discs, e.g. resilient for replacing the nucleus pulposus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2002/4495—Joints for the spine, e.g. vertebrae, spinal discs having a fabric structure, e.g. made from wires or fibres
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/38—Materials or treatment for tissue regeneration for reconstruction of the spine, vertebrae or intervertebral discs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A method of manufacturing a prosthetic spinal disc nucleus. The method including forming a hydrogel core from a hydrogel material in a natural state. The hydrogel material in the natural state is characterized by a natural swelling rate. The hydrogel is treated in an alkaline solution having a pH of at least about 8. This treatment transitions the hydrogel core from the natural state to a treated state characterized by an elevated swelling rate. The elevated swelling rate is greater that the natural swelling rate. The resultant, treated hydrogel core forms at least a portion of a prosthetic spinal disc nucleus. In one particular embodiment, the hydrogel core is inserted into a constraining jacket. Another aspect of the present invention relates to a prosthetic spinal disc nucleus including a hydrogel core having the elevated swelling rate.
PCT/US2003/037870 2002-11-26 2003-11-25 Prosthetic spinal disc nucleus with elevated swelling rate Ceased WO2004047690A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP03787185A EP1565130A2 (en) 2002-11-26 2003-11-25 Prosthetic spinal disc nucleus with elevated swelling rate
AU2003295970A AU2003295970A1 (en) 2002-11-26 2003-11-25 Prosthetic spinal disc nucleus with elevated swelling rate

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42933302P 2002-11-26 2002-11-26
US60/429,333 2002-11-26
US10/723,718 US20040143333A1 (en) 2002-11-26 2003-11-25 Prosthetic spinal disc nucleus with elevated swelling rate
US10/723,718 2003-11-25

Publications (3)

Publication Number Publication Date
WO2004047690A2 WO2004047690A2 (en) 2004-06-10
WO2004047690A3 true WO2004047690A3 (en) 2004-07-08
WO2004047690A8 WO2004047690A8 (en) 2004-10-21

Family

ID=32397196

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/037870 Ceased WO2004047690A2 (en) 2002-11-26 2003-11-25 Prosthetic spinal disc nucleus with elevated swelling rate

Country Status (4)

Country Link
US (2) US20040143333A1 (en)
EP (1) EP1565130A2 (en)
AU (1) AU2003295970A1 (en)
WO (1) WO2004047690A2 (en)

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Publication number Priority date Publication date Assignee Title
US6723335B1 (en) 2000-04-07 2004-04-20 Jeffrey William Moehlenbruck Methods and compositions for treating intervertebral disc degeneration
WO2004069296A1 (en) * 2003-01-31 2004-08-19 Zimmer Orthobiologics Inc. Hydrogel compositions comprising nucleus pulposus tissue
WO2005077013A2 (en) 2004-02-06 2005-08-25 Georgia Tech Research Corporation Surface directed cellular attachment
EP1729678A4 (en) 2004-02-06 2011-08-10 Georgia Tech Res Inst BEARING BIOCOMPATIBLE DEVICE
US7235592B2 (en) 2004-10-12 2007-06-26 Zimmer Gmbh PVA hydrogel
US8696707B2 (en) * 2005-03-08 2014-04-15 Zyga Technology, Inc. Facet joint stabilization
US7182783B2 (en) 2005-04-25 2007-02-27 Sdgi Holdings, Inc. Selectively expandable composite structures for spinal arthroplasty
US7988735B2 (en) * 2005-06-15 2011-08-02 Matthew Yurek Mechanical apparatus and method for delivering materials into the inter-vertebral body space for nucleus replacement
US8021426B2 (en) * 2005-06-15 2011-09-20 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
US7442210B2 (en) 2005-06-15 2008-10-28 Jerome Segal Mechanical apparatus and method for artificial disc replacement
US7601172B2 (en) 2005-06-15 2009-10-13 Ouroboros Medical, Inc. Mechanical apparatus and method for artificial disc replacement
US7547319B2 (en) 2005-06-15 2009-06-16 Ouroboros Medical Mechanical apparatus and method for artificial disc replacement
US20070162135A1 (en) * 2005-06-15 2007-07-12 Jerome Segal Mechanical apparatus and method for artificial disc replacement
GB0523999D0 (en) * 2005-11-25 2006-01-04 Univ Manchester Microgel particle
WO2007067697A2 (en) 2005-12-07 2007-06-14 Zimmer, Inc. Methods of bonding or modifying hydrogels using irradiation
DE602006017160D1 (en) 2005-12-22 2010-11-11 Zimmer Inc Perfluorocyclobutane crosslinked hydrogels
WO2007134113A2 (en) * 2006-05-09 2007-11-22 Raymedica, Llc Systems and methods for stabilizing a functional spinal unit
WO2008002482A2 (en) * 2006-06-23 2008-01-03 Surmodics, Inc. Hydrogel-based joint repair system and method
US20080215151A1 (en) * 2007-03-02 2008-09-04 Andrew Kohm Bone barrier device, system, and method
US7731988B2 (en) 2007-08-03 2010-06-08 Zimmer, Inc. Multi-polymer hydrogels
US8062739B2 (en) 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US7947784B2 (en) 2007-11-16 2011-05-24 Zimmer, Inc. Reactive compounding of hydrogels
US8034362B2 (en) 2008-01-04 2011-10-11 Zimmer, Inc. Chemical composition of hydrogels for use as articulating surfaces
US8663293B2 (en) 2010-06-15 2014-03-04 Zyga Technology, Inc. Systems and methods for facet joint treatment
WO2012162552A1 (en) 2011-05-26 2012-11-29 Cartiva, Inc. Tapered joint implant and related tools
US20130282121A1 (en) * 2012-03-22 2013-10-24 Ann Prewett Spinal facet augmentation implant and method
WO2014078541A1 (en) 2012-11-15 2014-05-22 Zyga Technology, Inc. Systems and methods for facet joint treatment
WO2016161025A1 (en) 2015-03-31 2016-10-06 Cartiva, Inc. Hydrogel implants with porous materials and methods
EP3636226A1 (en) 2015-03-31 2020-04-15 Cartiva, Inc. Carpometacarpal (cmc) implants
AU2016248062B2 (en) 2015-04-14 2020-01-23 Stryker Corporation Tooling for creating tapered opening in tissue and related methods
US10912867B2 (en) * 2017-11-15 2021-02-09 De Novo Orthopedics Inc. Bioinductive patch

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US5159360A (en) * 1990-07-17 1992-10-27 Kingston Technologies, Inc. Contact lens with pre-determined useful life
US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US20020082699A1 (en) * 2000-11-09 2002-06-27 Ward Robert S. Devices that change size/shape via osmotic pressure
WO2002076336A2 (en) * 2001-03-22 2002-10-03 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device

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US82699A (en) * 1868-10-06 farmer
NL7908799A (en) * 1978-12-22 1980-06-24 Tno PROCESS FOR PREPARING A POLYMER MIX, PRODUCTS PRODUCED THEREFROM AND POLYMER ALLOY.
US5192326A (en) * 1990-12-21 1993-03-09 Pfizer Hospital Products Group, Inc. Hydrogel bead intervertebral disc nucleus
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US5632774A (en) * 1995-01-17 1997-05-27 Babian; Hamik In-the-shell hydration to make implant filler material and prosthesis employing same
US6271278B1 (en) * 1997-05-13 2001-08-07 Purdue Research Foundation Hydrogel composites and superporous hydrogel composites having fast swelling, high mechanical strength, and superabsorbent properties
US6132465A (en) * 1998-06-04 2000-10-17 Raymedica, Inc. Tapered prosthetic spinal disc nucleus
US6605294B2 (en) * 1998-08-14 2003-08-12 Incept Llc Methods of using in situ hydration of hydrogel articles for sealing or augmentation of tissue or vessels

Patent Citations (4)

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US5788687A (en) * 1994-02-01 1998-08-04 Caphco, Inc Compositions and devices for controlled release of active ingredients
US20020082699A1 (en) * 2000-11-09 2002-06-27 Ward Robert S. Devices that change size/shape via osmotic pressure
WO2002076336A2 (en) * 2001-03-22 2002-10-03 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
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Also Published As

Publication number Publication date
US20040143333A1 (en) 2004-07-22
WO2004047690A8 (en) 2004-10-21
AU2003295970A1 (en) 2004-06-18
WO2004047690A2 (en) 2004-06-10
EP1565130A2 (en) 2005-08-24
AU2003295970A8 (en) 2004-06-18
US20060237877A1 (en) 2006-10-26

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