WO2004083810A3 - Maldi mass spectrometer having a laser steering assembly and method operating the same - Google Patents

Maldi mass spectrometer having a laser steering assembly and method operating the same Download PDF

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Publication number
WO2004083810A3
WO2004083810A3 PCT/US2004/006649 US2004006649W WO2004083810A3 WO 2004083810 A3 WO2004083810 A3 WO 2004083810A3 US 2004006649 W US2004006649 W US 2004006649W WO 2004083810 A3 WO2004083810 A3 WO 2004083810A3
Authority
WO
WIPO (PCT)
Prior art keywords
mass spectrometer
steering assembly
maldi mass
same
laser steering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/006649
Other languages
French (fr)
Other versions
WO2004083810A2 (en
Inventor
James P Reilly
Kirk S Boraas
Noah P Christian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Indiana University Research and Technology Corp
Original Assignee
Indiana University Research and Technology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/603,526 external-priority patent/US20040183009A1/en
Application filed by Indiana University Research and Technology Corp filed Critical Indiana University Research and Technology Corp
Priority to EP04717969A priority Critical patent/EP1604381A2/en
Publication of WO2004083810A2 publication Critical patent/WO2004083810A2/en
Publication of WO2004083810A3 publication Critical patent/WO2004083810A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/161—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission using photoionisation, e.g. by laser
    • H01J49/164—Laser desorption/ionisation, e.g. matrix-assisted laser desorption/ionisation [MALDI]

Landscapes

  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Electron Tubes For Measurement (AREA)

Abstract

A MALDI mass spectrometer has a laser steering assembly operable to steer or otherwise direct movement of a laser focus over the MALDI sample being tested. Such a laser steering assembly may include a mirror array having a pair of independently controlled mirrors. The first of such a pair of mirrors is operable to move the laser focus along the X-axis of the MALDI sample, whereas the second of such a pair of mirrors is operable to move the laser focus along the Y-axis of the MALDI sample. A method of operating a MALDI mass spectrometer is also disclosed.
PCT/US2004/006649 2003-03-17 2004-03-05 Maldi mass spectrometer having a laser steering assembly and method operating the same Ceased WO2004083810A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04717969A EP1604381A2 (en) 2003-03-17 2004-03-05 Maldi mass spectrometer having a laser steering assembly and method operating the same

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US45550503P 2003-03-17 2003-03-17
US45571403P 2003-03-17 2003-03-17
US60/455,714 2003-03-17
US60/455,505 2003-03-17
US10/603,526 US20040183009A1 (en) 2003-03-17 2003-06-25 MALDI mass spectrometer having a laser steering assembly and method of operating the same
US10/603,526 2003-06-25

Publications (2)

Publication Number Publication Date
WO2004083810A2 WO2004083810A2 (en) 2004-09-30
WO2004083810A3 true WO2004083810A3 (en) 2005-06-02

Family

ID=33033153

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/006649 Ceased WO2004083810A2 (en) 2003-03-17 2004-03-05 Maldi mass spectrometer having a laser steering assembly and method operating the same

Country Status (2)

Country Link
EP (1) EP1604381A2 (en)
WO (1) WO2004083810A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005006125B4 (en) * 2004-09-14 2021-04-29 Bruker Daltonik Gmbh Laser system for the ionization of a sample through matrix-assisted laser desorption in mass spectrometric analysis
US7385192B2 (en) 2005-02-10 2008-06-10 Bruker Daltonik, Gmbh Laser system for the ionization of a sample by matrix-assisted laser desorption in mass spectrometric analysis
GB201104225D0 (en) * 2011-03-14 2011-04-27 Micromass Ltd Pre scan for mass to charge ratio range

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020023410A1 (en) * 1996-09-17 2002-02-28 David Robert Seaward Apparatus and method for formation of sealed packages
US20020066857A1 (en) * 2000-08-24 2002-06-06 Hughey Barbara J. Sample introduction interface for analytical processing of a sample placed on a substrate
US20020148972A1 (en) * 2001-04-16 2002-10-17 Andrew Krutchinsky Method and system for mass spectroscopy
US6558902B1 (en) * 1998-05-07 2003-05-06 Sequenom, Inc. Infrared matrix-assisted laser desorption/ionization mass spectrometric analysis of macromolecules

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020023410A1 (en) * 1996-09-17 2002-02-28 David Robert Seaward Apparatus and method for formation of sealed packages
US6558902B1 (en) * 1998-05-07 2003-05-06 Sequenom, Inc. Infrared matrix-assisted laser desorption/ionization mass spectrometric analysis of macromolecules
US20020066857A1 (en) * 2000-08-24 2002-06-06 Hughey Barbara J. Sample introduction interface for analytical processing of a sample placed on a substrate
US20020148972A1 (en) * 2001-04-16 2002-10-17 Andrew Krutchinsky Method and system for mass spectroscopy

Also Published As

Publication number Publication date
WO2004083810A2 (en) 2004-09-30
EP1604381A2 (en) 2005-12-14

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