WO2004090151A3 - Method for extracting collagen comprising microbial fermentation - Google Patents

Method for extracting collagen comprising microbial fermentation Download PDF

Info

Publication number
WO2004090151A3
WO2004090151A3 PCT/IB2004/001439 IB2004001439W WO2004090151A3 WO 2004090151 A3 WO2004090151 A3 WO 2004090151A3 IB 2004001439 W IB2004001439 W IB 2004001439W WO 2004090151 A3 WO2004090151 A3 WO 2004090151A3
Authority
WO
WIPO (PCT)
Prior art keywords
collagen
microbial fermentation
extracting collagen
present
fermentation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2004/001439
Other languages
French (fr)
Other versions
WO2004090151A2 (en
Inventor
June Nam Seah
Chin Ying Hsiao
Chiang Hung Chou
Hsi Wen Sun
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EcoDynamic BioLab Inc
Original Assignee
EcoDynamic BioLab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EcoDynamic BioLab Inc filed Critical EcoDynamic BioLab Inc
Priority to DE602004018297T priority Critical patent/DE602004018297D1/en
Priority to EP04726881A priority patent/EP1616019B1/en
Priority to JP2006506591A priority patent/JP5079322B2/en
Publication of WO2004090151A2 publication Critical patent/WO2004090151A2/en
Publication of WO2004090151A3 publication Critical patent/WO2004090151A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a novel collagen production method wherein the collagen-containing tissues are fermented to extract the Collagen. The fermentation process employs microorganisms, including but is not limited to bacteria and yeast. The present invention is also directed to collagen product comprising collagen produced by fermentation.
PCT/IB2004/001439 2003-04-11 2004-04-12 Method for extracting collagen comprising microbial fermentation Ceased WO2004090151A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE602004018297T DE602004018297D1 (en) 2003-04-11 2004-04-12 COLLAGEN EXTRACTION PROCESS CONSISTS OF MICROBIAL FERMENTATION
EP04726881A EP1616019B1 (en) 2003-04-11 2004-04-12 Method for extracting collagen comprising microbial fermentation
JP2006506591A JP5079322B2 (en) 2003-04-11 2004-04-12 New collagen production method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46252803P 2003-04-11 2003-04-11
US60/462,528 2003-04-11

Publications (2)

Publication Number Publication Date
WO2004090151A2 WO2004090151A2 (en) 2004-10-21
WO2004090151A3 true WO2004090151A3 (en) 2004-12-23

Family

ID=33159851

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/001439 Ceased WO2004090151A2 (en) 2003-04-11 2004-04-12 Method for extracting collagen comprising microbial fermentation

Country Status (7)

Country Link
US (1) US7396912B2 (en)
EP (1) EP1616019B1 (en)
JP (1) JP5079322B2 (en)
CN (1) CN1802437A (en)
AT (1) ATE417121T1 (en)
DE (1) DE602004018297D1 (en)
WO (1) WO2004090151A2 (en)

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KR100676285B1 (en) * 2005-03-11 2007-01-30 세원셀론텍(주) Method for isolating collagen from various tissues of animal and preparing collagen solution and matrix produced using the same
WO2007002074A2 (en) * 2005-06-21 2007-01-04 Biova, L.L.C. Avian eggshell membrane polypeptide extraction via fermentation process
WO2010022073A1 (en) * 2008-08-19 2010-02-25 Dbc, Llc Compositions and methods for utilizing the same
JP5753356B2 (en) * 2010-09-13 2015-07-22 株式会社龍泉堂 Method for extracting non-denatured type II collagen having an active epitope
KR101248617B1 (en) 2010-12-30 2013-03-28 한국식품연구원 A method of extracting collagen by ultrasonication
KR101254403B1 (en) * 2011-01-06 2013-04-15 샘표식품 주식회사 Method for Preparing Fermented Collagen Peptide
CN102318843B (en) * 2011-07-01 2013-08-21 中国科学院海洋研究所 Scale collagen polypeptide and preparation method thereof
US8344106B1 (en) 2011-08-03 2013-01-01 Robert den Hoed Collagen mixture and method of making the same
JP5522857B2 (en) * 2011-12-05 2014-06-18 多木化学株式会社 Method for producing collagen
SMT202100257T1 (en) * 2012-01-09 2021-07-12 Innocoll Pharm Ltd A modified collagen
KR101551412B1 (en) * 2013-05-01 2015-09-08 (주)청룡수산 A cosmetic composition comprising enzymatic extracts from branchiostegus japonicus
PL2996704T3 (en) * 2013-05-14 2021-06-28 Mars, Incorporated Joint care composition
US9370469B2 (en) * 2014-03-14 2016-06-21 Suneva Medical, Inc Injectable alloplastic implants and methods of use thereof
US9370603B2 (en) * 2014-03-14 2016-06-21 Suneva Medical, Inc. Injectable alloplastic implants and methods of use thereof
JP6408409B2 (en) * 2014-04-01 2018-10-17 兵庫県 Method for producing collagen fiber and method for producing high concentration collagen solution
US10694767B2 (en) 2014-04-28 2020-06-30 International Dehydrated Foods, Inc. Process for preparing a pumpable broth composition
CN104474535A (en) * 2014-12-10 2015-04-01 成都新际生物活性胶原开发有限公司 Water-soluble gel for treating diabetic foot
KR101840213B1 (en) * 2016-05-20 2018-03-20 주식회사 미싹바이오 Production method of low molecular collagen peptide and food composition using this low molecular collagen peptide
EP3471756B1 (en) * 2016-06-15 2025-07-30 International Dehydrated Foods, Inc. Process for preparing a pumpable broth composition
GB201708853D0 (en) * 2017-06-02 2017-07-19 Jellagen Pty Ltd Method
CN108913749A (en) * 2018-08-02 2018-11-30 艾苛密（上海）健康科技股份有限公司 Active peptide nanometre collagen and preparation method thereof
KR102387667B1 (en) * 2020-09-01 2022-04-20 농업회사법인 주식회사 옻가네 Method for extracting collagen using rhus verniciflua fermentation broth and composition for extracting collagen containing nontoxic fermented extract of rhus verniciflua as an active ingredient
CN113150116A (en) * 2021-03-18 2021-07-23 青海大学 Method for efficiently preparing antioxidant active peptide
CN114774501B (en) * 2022-05-10 2023-07-25 泸州品创科技有限公司 Fish skin collagen sponge material and preparation method thereof
KR102830099B1 (en) * 2022-08-29 2025-07-04 재단법인 순천바이오헬스케어연구센터 Low molecular protein material derived from fish-skin as fishery by-products and method of preparing therefor
CN116179634B (en) 2023-04-27 2023-08-18 北京盛美诺生物技术有限公司 III type collagen peptide and preparation method thereof

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US3616205A (en) * 1970-02-03 1971-10-26 Nihon Hikaku Kk Solubilization of insoluble collagen
US3681093A (en) * 1968-05-06 1972-08-01 Devro Inc Process for making edible collagen casings
DE2507223A1 (en) * 1975-02-20 1976-09-02 Trommsdorff Fa H Wound-healing partially degraded collagen prod - contg 25-50 pts monomeric collagen, 25-50 pts polymeric collagen and 0-40 wt pts highly polymeric collagen
US5480427A (en) * 1990-02-28 1996-01-02 Darby & Darby Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US6372794B1 (en) * 1999-08-26 2002-04-16 Marcel E. Nimni Method for alleviating arthritis in mammals
JP2004173653A (en) * 2002-11-29 2004-06-24 Takashi Kondo Health food product by using pig skin and method for producing the same

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GB1557005A (en) * 1975-07-11 1979-12-05 Novo Industri As Gelatine extraction
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US5436135A (en) 1985-09-02 1995-07-25 Pasteur Merieux Serums Et Vaccins New preparation of placenta collagen, their extraction method and their applications
GB8609809D0 (en) * 1986-04-22 1986-05-29 Hodgson Chemicals Ltd Protein product
US5106949A (en) 1989-09-15 1992-04-21 Organogenesis, Inc. Collagen compositions and methods for preparation thereof
EP0689769B1 (en) * 1994-06-29 1999-09-01 Societe Des Produits Nestle S.A. Fermented animal feed
CN1223561C (en) * 1999-06-30 2005-10-19 大日本油墨化学工业株式会社 Compound having tetrahydronalphthalene skeleton and liquid crystal compsn. contg. same
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KR100492371B1 (en) * 2002-05-01 2005-05-30 주식회사 부원바이오텍 Method for manufacturing mild water-soluble collagen
JP2003331979A (en) * 2002-05-10 2003-11-21 Sumitomo Wiring Syst Ltd Waterproof connector and rubber plug for sealing

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3681093A (en) * 1968-05-06 1972-08-01 Devro Inc Process for making edible collagen casings
US3616205A (en) * 1970-02-03 1971-10-26 Nihon Hikaku Kk Solubilization of insoluble collagen
DE2507223A1 (en) * 1975-02-20 1976-09-02 Trommsdorff Fa H Wound-healing partially degraded collagen prod - contg 25-50 pts monomeric collagen, 25-50 pts polymeric collagen and 0-40 wt pts highly polymeric collagen
US5480427A (en) * 1990-02-28 1996-01-02 Darby & Darby Biologically compatible collagenous reaction product and articles useful as medical implants produced therefrom
US6372794B1 (en) * 1999-08-26 2002-04-16 Marcel E. Nimni Method for alleviating arthritis in mammals
JP2004173653A (en) * 2002-11-29 2004-06-24 Takashi Kondo Health food product by using pig skin and method for producing the same

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
ASDORNNITHEE S ET AL: "ISOLATION AND CHARACTERIZATION OF A COLLAGENOLYTIC ENZYME FROM BACILLUS LICHENIFORMIS N22", JOURNAL OF FERMENTATION AND BIOENGINEERING, SOCIETY OF FERMENTATION TECHNOLOGY, JP, vol. 78, no. 4, 1994, pages 283 - 287, XP001029493, ISSN: 0922-338X *
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; CRISTESCU, D. ET AL.: "DEPOLIMERIZATION OF SKIN COLLAGEN BY BACTERIAL ENZYMES", XP002296510, Database accession no. 1974:427217 *
DATABASE CHEMABS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002296511, Database accession no. 2004:512303 *
MAKINEN K K ET AL: "PURIFICATION AND PROPERTIES OF AN EXTRACELLULAR COLLAGENOLYTIC PROTEASE PRODUCED BY THE HUMAN ORAL BACTERIUM BACILLUS CEREUS (STRAIN SOC 67)", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 262, no. 26, 15 September 1987 (1987-09-15), pages 12488 - 12495, XP001029486, ISSN: 0021-9258 *
NAKAYAMA T ET AL: "THERMOSTABLE COLLAGENOLYTIC ACTIVITY OF A NOVEL THERMOPHILIC ISOLATE, BACILLUS SP. STRAIN NTAP-1", JOURNAL OF BIOSCIENCE AND BIOENGINEERING, ELSEVIER, AMSTERDAM,, NL, vol. 89, no. 6, 2000, pages 612 - 614, XP001029498, ISSN: 1389-1723 *

Also Published As

Publication number Publication date
US20040253678A1 (en) 2004-12-16
US7396912B2 (en) 2008-07-08
CN1802437A (en) 2006-07-12
JP5079322B2 (en) 2012-11-21
ATE417121T1 (en) 2008-12-15
DE602004018297D1 (en) 2009-01-22
EP1616019B1 (en) 2008-12-10
JP2006522601A (en) 2006-10-05
EP1616019A2 (en) 2006-01-18
WO2004090151A2 (en) 2004-10-21

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