WO2004100761A3 - System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation - Google Patents

System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation Download PDF

Info

Publication number
WO2004100761A3
WO2004100761A3 PCT/SE2004/000758 SE2004000758W WO2004100761A3 WO 2004100761 A3 WO2004100761 A3 WO 2004100761A3 SE 2004000758 W SE2004000758 W SE 2004000758W WO 2004100761 A3 WO2004100761 A3 WO 2004100761A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation
mechanical
therapy
site
diagnosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/SE2004/000758
Other languages
French (fr)
Other versions
WO2004100761A2 (en
Inventor
Ann Johansson
Engels Stefan Andersson
Thomas Johansson
Sara Paalsson
Thompson Marcelo Soto
Katarina Svanberg
Sune Svanberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Spectracure AB
Original Assignee
Spectracure AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0301411A external-priority patent/SE527192C2/en
Priority claimed from SE0301410A external-priority patent/SE527164C2/en
Priority claimed from SE0301406A external-priority patent/SE527162C2/en
Priority to EP04733227A priority Critical patent/EP1624796B1/en
Priority to JP2006532194A priority patent/JP4709157B2/en
Priority to US10/556,919 priority patent/US20070135873A1/en
Application filed by Spectracure AB filed Critical Spectracure AB
Priority to CA002566547A priority patent/CA2566547A1/en
Priority to AT04733227T priority patent/ATE547043T1/en
Priority to AU2004238183A priority patent/AU2004238183C1/en
Publication of WO2004100761A2 publication Critical patent/WO2004100761A2/en
Publication of WO2004100761A3 publication Critical patent/WO2004100761A3/en
Anticipated expiration legal-status Critical
Priority to US12/689,182 priority patent/US20100185099A1/en
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0613Apparatus adapted for a specific treatment
    • A61N5/062Photodynamic therapy, i.e. excitation of an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00057Light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/18Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
    • A61B18/20Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
    • A61B2018/208Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser with multiple treatment beams not sharing a common path, e.g. non-axial or parallel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A61B5/0086Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters using infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N5/0601Apparatus for use inside the body
    • A61N2005/0612Apparatus for use inside the body using probes penetrating tissue; interstitial probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00Radiation therapy
    • A61N5/06Radiation therapy using light
    • A61N2005/0626Monitoring, verifying, controlling systems and methods
    • A61N2005/0629Sequential activation of light sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

A system and method for therapy and diagnosis of a human or animal. At least one coupling element for coupling of radiation couples radiation from at least a first radiation source to a tumour site and/or from said second radiation source to said site and/or from said site to a detector. The coupling elements are combinations of at least one translatory distributor, at least one rotary distributor, and at least one operation mode selector means for directing either said therapeutic radiation or said diagnostic radiation to said site through said at least one first radiation conductor. The system may be used for interactive interstitial photodynamic tumour therapy. The system and method according to the invention combines the advantages of purely mechanical and purely non-mechanical solutions in a new and synergetic way.
PCT/SE2004/000758 2003-05-14 2004-05-14 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation Ceased WO2004100761A2 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
AU2004238183A AU2004238183C1 (en) 2003-05-14 2004-05-14 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation
AT04733227T ATE547043T1 (en) 2003-05-14 2004-05-14 TREATMENT AND DIAGNOSIS SYSTEM USING COMBINED NON-MECHANICAL AND MECHANICAL DISTRIBUTORS FOR DISTRIBUTING RADIATION
CA002566547A CA2566547A1 (en) 2003-05-14 2004-05-14 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation
JP2006532194A JP4709157B2 (en) 2003-05-14 2004-05-14 Treatment and diagnostic systems and methods comprising both non-mechanical and mechanical distributors for radiation delivery
US10/556,919 US20070135873A1 (en) 2003-05-14 2004-05-14 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation
EP04733227A EP1624796B1 (en) 2003-05-14 2004-05-14 System for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation
US12/689,182 US20100185099A1 (en) 2003-05-14 2010-01-18 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
SE0301411-5 2003-05-14
SE0301411A SE527192C2 (en) 2003-05-14 2003-05-14 Interactive therapy and diagnosis system for interstitial photodynamic therapy, has non-mechanical operating-mode selector to optically direct diagnostic and therapeutic radiation to treatment site through radiation conductor
SE0301406A SE527162C2 (en) 2003-05-14 2003-05-14 Interactive photodynamic photothermal therapy system for treatment of tumor, includes pair of longitudinal translatory displacement elements provided with holes to couple radiation in different constellations in different modes
SE0301410-7 2003-05-14
SE0301406-5 2003-05-14
SE0301410A SE527164C2 (en) 2003-05-14 2003-05-14 Interactive therapy/diagnosis system for tumor, has operation mode selector to optically direct non-ionizing electromagnetic therapeutic and/or diagnostic radiation to tumor site, through radiation conductor
US47085503P 2003-05-16 2003-05-16
US47085603P 2003-05-16 2003-05-16
US47085403P 2003-05-16 2003-05-16
US60/470,854 2003-05-16
US60/470,855 2003-05-16
US60/470,856 2003-05-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/689,182 Continuation US20100185099A1 (en) 2003-05-14 2010-01-18 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation

Publications (2)

Publication Number Publication Date
WO2004100761A2 WO2004100761A2 (en) 2004-11-25
WO2004100761A3 true WO2004100761A3 (en) 2005-01-20

Family

ID=44292690

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SE2004/000758 Ceased WO2004100761A2 (en) 2003-05-14 2004-05-14 System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation

Country Status (7)

Country Link
US (2) US20070135873A1 (en)
EP (1) EP1624796B1 (en)
JP (1) JP4709157B2 (en)
AT (1) ATE547043T1 (en)
AU (1) AU2004238183C1 (en)
CA (1) CA2566547A1 (en)
WO (1) WO2004100761A2 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE527164C2 (en) * 2003-05-14 2006-01-10 Spectracure Ab Interactive therapy/diagnosis system for tumor, has operation mode selector to optically direct non-ionizing electromagnetic therapeutic and/or diagnostic radiation to tumor site, through radiation conductor
US20070135873A1 (en) * 2003-05-14 2007-06-14 Ann Johansson System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation
US9044140B2 (en) 2004-06-30 2015-06-02 University Of Rochester Photodynamic therapy with spatially resolved dual spectroscopic monitoring
CN100366227C (en) * 2006-03-03 2008-02-06 华南师范大学 Method and device for monitoring photodynamic therapy effect of tumor by photoacoustic angiography
KR100798486B1 (en) * 2006-03-29 2008-01-28 한국전기연구원 Light source device for fluorescence diagnosis and photodynamic therapy
JP5472987B2 (en) 2006-08-15 2014-04-16 スペクトラキュアー アーベー System and method for controlling and adjusting tissue photodynamic phototherapy parameters
WO2008062000A1 (en) * 2006-11-20 2008-05-29 Spectracure Ab System and method for predicting and/or adjusting control parameters of interstitial photodynamic light therapy
WO2008137737A2 (en) * 2007-05-02 2008-11-13 University Of Rochester Feedback-controlled method for delivering photodynamic therapy and related instrumentation
CA3162577C (en) 2008-05-20 2023-09-26 University Health Network Device and method for fluorescence-based imaging and monitoring
US8353833B2 (en) 2008-07-18 2013-01-15 University Of Rochester Low-cost device for C-scan photoacoustic imaging
US8663210B2 (en) 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
US9375281B2 (en) 2009-07-20 2016-06-28 Koninklijke Philips N.V. Light application apparatus for applying light to an object
EP2380482A1 (en) * 2010-04-21 2011-10-26 Koninklijke Philips Electronics N.V. Extending image information
WO2012076631A1 (en) 2010-12-07 2012-06-14 Spectracure Ab System and method for interstitial photodynamic light therapy in combination with photosensitizers
CA2794226C (en) 2012-10-31 2020-10-20 Queen's University At Kingston Automated intraoperative ultrasound calibration
US9638604B2 (en) * 2014-04-02 2017-05-02 Illinois Tool Works Inc. Fiber optic video inspection system and method
WO2016011534A1 (en) 2014-07-24 2016-01-28 University Health Network Collection and analysis of data for diagnostic purposes
US10180248B2 (en) 2015-09-02 2019-01-15 ProPhotonix Limited LED lamp with sensing capabilities
CN105251090A (en) * 2015-11-09 2016-01-20 武汉海纳川科技有限公司 Laser and oxygen therapy terminal and laser and oxygen therapy assembly with therapy terminal
CN107088266A (en) * 2017-04-06 2017-08-25 中国人民解放军总医院 Photodynamic therapy system with visualization function
CN110433404B (en) * 2019-08-13 2020-08-14 尚华 Wavelength conversion device
WO2022039973A1 (en) * 2020-08-18 2022-02-24 Simphotek, Inc. Interstitial photodynamic therapy
US20230152228A1 (en) * 2021-11-18 2023-05-18 Optomak, Inc. System, method and optical module for multi-fiber photometry with patterned sample stimulation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0195375A2 (en) * 1985-03-22 1986-09-24 Massachusetts Institute Of Technology Catheter for laser angiosurgery
EP0280397A2 (en) * 1987-02-25 1988-08-31 Edwin L. Adair Endoscope
EP0523417A1 (en) * 1991-07-16 1993-01-20 Isotopen-Technik Dr. Sauerwein Gmbh Pipe canal shunt
US6416531B2 (en) * 1998-06-24 2002-07-09 Light Sciences Corporation Application of light at plural treatment sites within a tumor to increase the efficacy of light therapy
WO2002074339A1 (en) * 2001-03-16 2002-09-26 University Of Utah Research Foundation Deveice and method for the photodynamic diagnosis of tumor tissue
EP1314451A1 (en) * 2001-11-23 2003-05-28 Nucletron B.V. Device for effecting radiation therapy in an animal body

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4155816A (en) * 1978-09-29 1979-05-22 The Goodyear Tire & Rubber Company Method of electroplating and treating electroplated ferrous based wire
US4496211A (en) * 1980-12-05 1985-01-29 Maurice Daniel Lightpipe network with optical devices for distributing electromagnetic radiation
US4491384A (en) * 1981-01-17 1985-01-01 Omron Tateisi Electronics Co. Optical switch device
JPS5940830A (en) * 1982-08-31 1984-03-06 浜松ホトニクス株式会社 Apparatus for diagnosis of cancer using laser beam pulse
US4669467A (en) * 1985-03-22 1987-06-02 Massachusetts Institute Of Technology Mode mixer for a laser catheter
JPS62143920U (en) * 1986-03-04 1987-09-10
US4981138A (en) * 1988-06-30 1991-01-01 Yale University Endoscopic fiberoptic fluorescence spectrometer
US5045072A (en) * 1989-06-13 1991-09-03 Cordis Corporation Catheter having highly radiopaque, flexible tip
JPH047850U (en) * 1990-05-09 1992-01-24
US5128797A (en) * 1991-02-11 1992-07-07 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Non-mechanical optical path switching and its application to dual beam spectroscopy including gas filter correlation radiometry
DE4213424C2 (en) * 1991-04-26 1996-03-07 Matsushita Electric Works Ltd Device for selectively feeding a laser beam to one of several laser welding stations
US6214033B1 (en) * 1992-12-28 2001-04-10 Matsushita Electric Industrial Co., Ltd. Medical laser apparatus and diagnostic/treatment apparatus using the medical laser apparatus
JP2915249B2 (en) * 1993-05-31 1999-07-05 株式会社長田中央研究所 Laser therapy equipment
US5454794A (en) * 1993-10-15 1995-10-03 Pdt Systems, Inc. Steerable light diffusing catheter
US6138046A (en) * 1999-04-20 2000-10-24 Miravant Medical Technologies, Inc. Dosimetry probe
AU2001251134B2 (en) * 2000-03-31 2006-02-02 Angiodynamics, Inc. Tissue biopsy and treatment apparatus and method
US6975898B2 (en) * 2000-06-19 2005-12-13 University Of Washington Medical imaging, diagnosis, and therapy using a scanning single optical fiber system
US6493139B1 (en) * 2001-03-16 2002-12-10 Hongdu Liu Optical switch
US20020186921A1 (en) * 2001-06-06 2002-12-12 Schumacher Lynn C. Multiwavelength optical fiber devices
US6950568B2 (en) * 2002-02-14 2005-09-27 Varian, Inc. Fiber-optic channel selecting apparatus
US7988715B2 (en) * 2003-05-14 2011-08-02 Spectracure Ab System and method for therapy and diagnosis comprising translatory distributor for distribution of radiation
US20070135873A1 (en) * 2003-05-14 2007-06-14 Ann Johansson System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0195375A2 (en) * 1985-03-22 1986-09-24 Massachusetts Institute Of Technology Catheter for laser angiosurgery
EP0280397A2 (en) * 1987-02-25 1988-08-31 Edwin L. Adair Endoscope
EP0523417A1 (en) * 1991-07-16 1993-01-20 Isotopen-Technik Dr. Sauerwein Gmbh Pipe canal shunt
US6416531B2 (en) * 1998-06-24 2002-07-09 Light Sciences Corporation Application of light at plural treatment sites within a tumor to increase the efficacy of light therapy
WO2002074339A1 (en) * 2001-03-16 2002-09-26 University Of Utah Research Foundation Deveice and method for the photodynamic diagnosis of tumor tissue
EP1314451A1 (en) * 2001-11-23 2003-05-28 Nucletron B.V. Device for effecting radiation therapy in an animal body

Also Published As

Publication number Publication date
AU2004238183C1 (en) 2010-09-09
JP4709157B2 (en) 2011-06-22
US20100185099A1 (en) 2010-07-22
JP2007502686A (en) 2007-02-15
ATE547043T1 (en) 2012-03-15
CA2566547A1 (en) 2004-11-25
EP1624796B1 (en) 2012-02-29
AU2004238183B2 (en) 2010-04-29
AU2004238183A1 (en) 2004-11-25
US20070135873A1 (en) 2007-06-14
WO2004100761A2 (en) 2004-11-25
EP1624796A2 (en) 2006-02-15

Similar Documents

Publication Publication Date Title
WO2004100761A3 (en) System and method for therapy and diagnosis comprising in combination non-mechanical and mechanical distributors for distribution of radiation
SE0301410D0 (en) System and method for therapy and diagnosis comprising optical components for distribution of radiation
WO2004014215A3 (en) Brachytherapy seed deployment system
SE0103771D0 (en) Distributors for distribution of radiation
Caracò et al. Long-lasting response to electrochemotherapy in melanoma patients with cutaneous metastasis
AU2001297644A1 (en) B/b-like fragment targeting for the purposes of photodynamic therapy and medical imaging
Rades et al. Treatment of painful bone metastases
DK1152792T3 (en) Microwave devices for medical hyperthermia, thermotherapy and diagnosis
WO2011130534A3 (en) Renal artery denervation apparatus employing helical shaping arrangement
WO2004113571A3 (en) Prostate specific genes and the use thereof as targets for prostate cancer therapy and diagnosis
WO2008008483A3 (en) Dendrimer based compositions and methods of using the same
AU2611800A (en) Photon irradiation human pain treatment monitored by thermal imaging
WO2006033766A3 (en) Dendrimer based compositions and methods of using the same
TR200102707T2 (en) Preparing and using radium-223 for contaminated target tissues for pain relief, bone cancer therapy and healthy bone surface retention.
WO2003087831A3 (en) Proteins involved in breast cancer
Gerszten Spine metastases: from radiotherapy, surgery, to radiosurgery
WO2002076548A3 (en) Methods and apparatus for treating diseased tissue
WO1998045328A3 (en) Compositions and methods for the treatment and diagnosis of breast cancer
KR101406370B1 (en) Capsule endoscope for photodynamic and sonodynamic therapy
ATE421356T1 (en) TREATMENT AND DIAGNOSIS SYSTEM WITH TRANSLATORY DISTRIBUTOR FOR RADIATION DISTRIBUTION
MXPA01010186A (en) Compositions and methods for the treatment and diagnosis of breast cancer.
PT1472375E (en) GENDER PRODUCTS DIFFERENTIALLY EXPRESSED IN BREAST CANCERIAN CELLS AND THEIR METHODS OF USE
Coghlan et al. Cerebral radionecrosis following the treatment of parotid tumours: a case report and review of the literature
WO2008005435A2 (en) Endoscopic/percutaneous electronic radiation applicator and method of use
Yoong et al. Percutaneous sacroplasty for painful bone metastases: a case report

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2006532194

Country of ref document: JP

Ref document number: 20048130705

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 2004733227

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2004238183

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2004238183

Country of ref document: AU

Date of ref document: 20040514

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004238183

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004733227

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2566547

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2007135873

Country of ref document: US

Ref document number: 10556919

Country of ref document: US

WWP Wipo information: published in national office

Ref document number: 10556919

Country of ref document: US