WO2004102609A1 - Fluorescent x-ray source - Google Patents
Fluorescent x-ray source Download PDFInfo
- Publication number
- WO2004102609A1 WO2004102609A1 PCT/IB2004/050653 IB2004050653W WO2004102609A1 WO 2004102609 A1 WO2004102609 A1 WO 2004102609A1 IB 2004050653 W IB2004050653 W IB 2004050653W WO 2004102609 A1 WO2004102609 A1 WO 2004102609A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- rays
- target
- liquid metal
- primary
- ray source
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J35/00—X-ray tubes
- H01J35/02—Details
- H01J35/04—Electrodes ; Mutual position thereof; Constructional adaptations therefor
- H01J35/08—Anodes; Anti cathodes
- H01J35/12—Cooling non-rotary anodes
- H01J35/13—Active cooling, e.g. fluid flow, heat pipes
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J2235/00—X-ray tubes
- H01J2235/08—Targets (anodes) and X-ray converters
- H01J2235/081—Target material
- H01J2235/082—Fluids, e.g. liquids, gases
Definitions
- the present invention relates to an X-ray source for the generation of fluorescent X-rays comprising an electron source for the emission of electrons and a target which emits X-rays in response to the incidence of the electrons, said target comprising a ring-shaped primary target for the emission of primary X-rays in response to the incidence of the electrons and a secondary target for the emission of fluorescent X-rays in response to the incidence of the primary X-rays.
- the invention further relates to an X-ray anode for the emission of fluorescent X-rays in response to the incidence of electrons, said anode comprising a ring-shaped primary target for the emission of primary X-rays in response to the incidence of the electrons and a secondary target for the emission of fluorescent X-rays in response to the incidence of the primary X-rays.
- Monochromatic X-ray sources enhance the performance of conventional X-ray techniques and enable innovative ones.
- Such monochromatic X-ray sources are, for instance, described in US 4,903,287 and US 5,157,704.
- the anode also called primary target, which encloses a member, also called secondary target, is struck by electrons on its side which faces the member and in which the primary X-ray radiation generated in the anode generates fluorescent radiation in the member.
- the member is preferably arranged within an enclosing shield which keeps scattered electrons remote from the member. This principle is often referred to as Fluorex principle.
- the fundamental X-ray interaction cross-sections such as Compton scattering, photoelectric absorption and coherent X-ray scatter, are all energy-dependent. It has traditionally been assumed in diagnostic radiology that the continuous spectrum emitted by polychromatic radiation sources (electron-impact) can be approximated by a monochromatic line of "average” energy.
- CT computed tomography
- the beam hardening artefact of computed tomography (CT) is evidence that his approximation must be abandoned when accurate results for the attenuation coefficient are desired.
- CT computed tomography
- the "average energy” approximation breaks down even more seriously in novel X-ray techniques such as coherent scatter CT or TEAMFI, which ideally require monochromatic radiation.
- Such radiation sources are either weak (e.g. radionuclides) or inconvenient (e.g. synchrotrons).
- Another type of monochromatic X-ray source which is based on the so-called
- LIMAX principle is described in US 6,185,277.
- a liquid metal target is provided.
- the electrons emitted by the electron source enter the liquid metal through a thin window and produce X-rays therein.
- the liquid metal having a high atomic number, circulates under the influence of a pump, so that the heat produced by the interaction with the electrons in the window and the liquid metal can be dissipated.
- the heat generated at this area is dissipated by a turbulent flow, thus ensuring effective cooling.
- an X-ray source for the generation of fluorescent X-rays according to the invention and an X-ray anode for the emission of fluorescent X-rays according to the invention are both characterized in that said primary target comprises a liquid metal channel arranged in radial direction relative to a central axis, a liquid metal circulating in said liquid metal channel during operation of the X-ray source in radial direction from an inner side to an outer side of said ring-shaped primary target.
- the present invention is based on a combination of the Fluorex principle with the liquid metal anode X-ray technique, which permits a large increase in source radiance. To obtain this increased radiance, a radial flow geometry is used in the liquid metal channel.
- the circular-symmetric geometry of the primary and secondary targets maximizes, for a certain size (i.e. focus dimension) of the secondary target, the mean solid angle, ⁇ mean , which the secondary target subtends at the primary target.
- the radial flow arrangement correspondingly maximizes the power with which the ring-shaped circular-symmetric primary target can be loaded.
- the performance of conventional radiological techniques can be enhanced and novel radiological techniques are enabled to be practically realized.
- Preferred embodiments of the invention are defined in the dependent claims. It is, for instance, advantageous that the secondary target is arranged on the central axis of the ring-shaped primary target and is adapted to emit the fluorescent X-rays substantially in directions parallel to said central axis. This arrangement is most effective with respect to efficiency of use of primary X-rays. The fluorescent X-rays will thus be emitted through the central hole of the ring-shaped primary target.
- the liquid metal channel comprises a constriction in an electron impact zone in which the electrons hit the primary target. This ensures that at an electron window, where the electrons are incident, the pressure on the window is minimized, i.e. the viscous pressure drop across the electron window is balanced by an increase in the Bernoulli pressure.
- the surface of the primary target facing the electron source is covered by a metal membrane, for instance a foil.
- This membrane serves for separating the vacuum region of the X-ray source from the liquid metal channel behind the membrane.
- the liquid metal circulating in the liquid metal channel preferably comprises a material having a high atomic number to ensure that sufficient X-rays are generated therein upon incidence of the electrons.
- the liquid metal has an atomic number larger than 40 and smaller than 80.
- the liquid metal may comprise an alloy of Bi, Pb, In or Sn.
- radial fins are further provided to divide the liquid metal channel into a number of radial subchannels.
- the liquid metal can only flow in radial direction but not in circular direction, i.e. in a direction around the central axis.
- Fig. 1 shows an emission spectrum of a known Fluorex device having a Ta target
- Fig. 2 shows a central cross-section through an X-ray source according to the invention
- Fig. 3 shows an enlarged portion of a primary target of the X-ray source shown in Fig. 1; and Fig. 4 shows an end surface of the primary target shown in Fig. 3 when viewed along the direction of a central axis of the X-ray source.
- Fig. 1 shows an emission spectrum of a known Fluorex device having a Ta target as marketed by Philips.
- the fluorescent radiation originates via the photoelectric effect in a secondary target (of Ta in this device) which is irradiated by a continuous X-ray spectrum whose maximum photon energy is significantly higher (a factor of 3) than the K absorption edge of the secondary target.
- the photon output of this device is proportional to the power of the primary X-ray beam which falls on the secondary target.
- a higher radiance is therefore feasible when the primary power is increased.
- the primary beam is emitted by a water-cooled stationary anode which limits the applied power of the electron beam to approximately 10 kW.
- the purpose of the present invention is to radically increase the permissible power by arranging for the electron beam to interact with a turbulently-flowing liquid metal.
- FIG. 2 A central cross-section through the arrangement of an X-ray source according to the invention is shown in Fig. 2.
- the arrangement essentially comprises a cathode 1 and a target (anode) having a primary target (also called end cap) 2 and a secondary target 3.
- the arrangement is circularly symmetric around the central (rotational) axis 4 and is located inside a housing 5.
- An electron beam 6 emitted from the ring cathode 1 impacts on a membrane (foil) 7 of the primary target 2.
- the foil 7 is of a material (e.g. W) which is sufficiently thin, in order that the electrons lose a negligible proportion of their original energy therein.
- the primary target 2 further comprises a liquid metal channel 8 which allows a liquid metal to circulate in radial direction relative to the central axis 4 from an inner side 13 to an outer side 14 of the ring-shaped primary target 2.
- Fig. 3 is an enlarged view of one half of the primary target 2 shown in Fig. 2.
- the foil 7 serves the purpose of separating the vacuum region of the X-ray tube from a liquid metal behind the foil 7.
- the liquid metal can be an alloy of e.g. Bi, Pb, In, Sn, etc., but should at least have a high atomic number, preferably between 40 and 80.
- the electrons 6 diffuse into the liquid metal, thereby loosing energy which is converted into heat.
- the total power which can be dissipated in the liquid metal is much larger than that of a stationary anode X-ray tube.
- the direction of motion of the liquid metal can be gauged from the arrows showing the flow direction in Fig. 3. It enters the primary target 2 at a comparatively small radius and leaves it again at a comparatively large radius. Further elements such as a heat exchanger, liquid metal pump, etc. can be added to the arrangement in Fig. 2 to yield a closed circuit for the liquid metal channel 8 around which the liquid metal is repetitively circulated.
- Primary X-rays 9 are generated in the electron membrane 7 and in the liquid metal 8, providing this has a relatively high Z. As shown in Fig. 2, these X-rays 9 hit the secondary target 3 through an X-ray window 11 (e. g. of Be) and excite fluorescent radiation 10.
- the secondary target 3 shows a cone-shaped form of a circular cross-section with a tip facing away from the cathode 2 in the direction of the central axis 4. Further, a primary beam stop 12 is provided on the side facing the cathode 1 to prevent X-rays 9 from hitting the cathode 1.
- the fluorescent radiation 10 leaves the X-ray tube along the direction of the central axis 4 through an exit window 16 in the primary target 2 and the housing 5.
- the primary target 2 is illustrated in Fig. 4 when viewed in the direction of the central axis 4.
- the primary target 2 serves several purposes. First, it absorbs all the other radiation generated in the X-ray tube by the electron beam, X-ray scatter events etc. To this end the end cap has an equivalent thickness of several mm Pb.
- the primary target 2 has a circular channel (inlet) 13 at a comparatively small radius, through which liquid metal is fed into the anode, and a similar channel (outlet) 14 at a comparatively large radius, through which liquid metal is transported to a pump etc.
- the primary target 2 has a form which matches with the liquid metal circuit 8 (i.e. confusor, constriction and diffusor) and supports the electron window 7.
- the part of the primary target 2 to the left of the liquid metal channel 8 in Fig. 3 is provided with fins 17 which direct the liquid metal to move in a strictly radial sense from the inner (feed) to the outer (outlet) radius.
- the liquid metal channel 8 shows a cross-sectional area (channel height x circumference) across which the liquid flow is held constant. As the radius increases (from the inlet 13 to the outlet 14) the channel height is reduced. Radial flow of the liquid metal is ensured by the fins 17. Further, the pressure on the electron window 7 can be minimised by ensuring that the viscous pressure drop across the window 7 is balanced by an increase in the Bernoulli pressure. In the radial embodiment of the liquid channel 8 the pressure drop across the window is not linear with the radius. To achieve a minimum pressure at the electron window 7, the liquid channel comprises a constriction 15 at an electron impact zone where most or all of the electrons 6 are incident.
- the present invention provides a high-brightness quasi-monochromatic X-ray source for the generation of fluorescent X-rays. It employs a liquid metal target in a circularly-symmetric flow geometry to yield a primary beam of high intensity (factor ten improvement over known Fluorex design). When this beam irradiates the exchangeable secondary target, a high intensity beam of fluorescent photons results.
- the enhanced radiance of this arrangement enables practical realization of otherwise unrealistic radiological techniques such as molecular imaging, tissue characterization with coherent X-ray scatter, and baggage inspection.
Landscapes
- Physics & Mathematics (AREA)
- Fluid Mechanics (AREA)
- X-Ray Techniques (AREA)
- Luminescent Compositions (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
Abstract
Description
Claims
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04732386A EP1627409B1 (en) | 2003-05-19 | 2004-05-12 | Fluorescent x-ray source |
| DE602004016320T DE602004016320D1 (en) | 2003-05-19 | 2004-05-12 | Fluorescent X-RAY SOURCE |
| US10/556,612 US7567650B2 (en) | 2003-05-19 | 2004-05-12 | Fluorescent x-ray source |
| JP2006530814A JP2007503703A (en) | 2003-05-19 | 2004-05-12 | X-ray fluorescence source |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03101401 | 2003-05-19 | ||
| EP03101401.2 | 2003-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2004102609A1 true WO2004102609A1 (en) | 2004-11-25 |
Family
ID=33442843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2004/050653 Ceased WO2004102609A1 (en) | 2003-05-19 | 2004-05-12 | Fluorescent x-ray source |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7567650B2 (en) |
| EP (1) | EP1627409B1 (en) |
| JP (1) | JP2007503703A (en) |
| CN (1) | CN1791960A (en) |
| AT (1) | ATE407446T1 (en) |
| DE (1) | DE602004016320D1 (en) |
| WO (1) | WO2004102609A1 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007207548A (en) * | 2006-02-01 | 2007-08-16 | Toshiba Electron Tubes & Devices Co Ltd | X-ray source and fluorescent X-ray analyzer |
| EP2298671A1 (en) | 2004-09-17 | 2011-03-23 | Tuttoespresso S.r.l. | Disposable capsule for beverages |
| US11744536B2 (en) | 2018-02-09 | 2023-09-05 | Imagine Scientific, Inc. | Monochromatic x-ray imaging systems and methods |
| US11833369B2 (en) | 2017-05-19 | 2023-12-05 | Imagine Scientific, Inc. | Monochromatic x-ray imaging systems and methods |
| US11903754B2 (en) | 2009-04-16 | 2024-02-20 | Imagine Scientific, Inc. | Monochromatic X-ray methods and apparatus |
| US12253480B2 (en) | 2014-06-24 | 2025-03-18 | Imagine Scientific, Inc. | Methods and apparatus for determining information regarding chemical composition using x-ray radiation |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10818467B2 (en) | 2018-02-09 | 2020-10-27 | Imagine Scientific, Inc. | Monochromatic x-ray imaging systems and methods |
| WO2020056281A1 (en) * | 2018-09-14 | 2020-03-19 | Imagine Scientific, Inc. | Monochromatic x-ray component systems and methods |
| CN109730706A (en) * | 2019-01-28 | 2019-05-10 | 深圳市纳诺艾医疗科技有限公司 | A kind of local second-order fluorescence radiation X bulb |
| JP2022522541A (en) * | 2019-04-26 | 2022-04-19 | イーユーブイ ラブス,リミテッド | Rotating liquid-X-ray source with metal target and radiation generation method |
| CN115020172A (en) * | 2022-07-01 | 2022-09-06 | 成都理工大学 | Annular electron beam reflection type liquid metal anode device |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2108149A1 (en) * | 1970-07-29 | 1972-05-19 | Alsacienne Atom | Liquid metal-cooled cell - for equipment receiving a continuous heat flux |
| DE19639241A1 (en) * | 1996-09-24 | 1998-04-02 | Siemens Ag | Monochromatic X-ray source e.g. for medical diagnostics |
| EP1102302A1 (en) * | 1999-11-18 | 2001-05-23 | Philips Patentverwaltung GmbH | Monochromatic x-ray source |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3716618A1 (en) * | 1987-05-18 | 1988-12-08 | Philips Patentverwaltung | RADIATION SOURCE FOR GENERATING AN ESSENTIAL MONOCHROMATIC X-RAY RADIATION |
| DE4017002A1 (en) * | 1990-05-26 | 1991-11-28 | Philips Patentverwaltung | Monochromatic X=radiation source |
| DE19821939A1 (en) * | 1998-05-15 | 1999-11-18 | Philips Patentverwaltung | X-ray tube with a liquid metal target |
| JP4294492B2 (en) * | 2002-03-08 | 2009-07-15 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | X-ray generator having a liquid metal anode |
-
2004
- 2004-05-12 US US10/556,612 patent/US7567650B2/en not_active Expired - Fee Related
- 2004-05-12 EP EP04732386A patent/EP1627409B1/en not_active Expired - Lifetime
- 2004-05-12 AT AT04732386T patent/ATE407446T1/en not_active IP Right Cessation
- 2004-05-12 JP JP2006530814A patent/JP2007503703A/en not_active Withdrawn
- 2004-05-12 DE DE602004016320T patent/DE602004016320D1/en not_active Expired - Fee Related
- 2004-05-12 CN CNA2004800136932A patent/CN1791960A/en active Pending
- 2004-05-12 WO PCT/IB2004/050653 patent/WO2004102609A1/en not_active Ceased
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2108149A1 (en) * | 1970-07-29 | 1972-05-19 | Alsacienne Atom | Liquid metal-cooled cell - for equipment receiving a continuous heat flux |
| DE19639241A1 (en) * | 1996-09-24 | 1998-04-02 | Siemens Ag | Monochromatic X-ray source e.g. for medical diagnostics |
| EP1102302A1 (en) * | 1999-11-18 | 2001-05-23 | Philips Patentverwaltung GmbH | Monochromatic x-ray source |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2298671A1 (en) | 2004-09-17 | 2011-03-23 | Tuttoespresso S.r.l. | Disposable capsule for beverages |
| JP2007207548A (en) * | 2006-02-01 | 2007-08-16 | Toshiba Electron Tubes & Devices Co Ltd | X-ray source and fluorescent X-ray analyzer |
| US11903754B2 (en) | 2009-04-16 | 2024-02-20 | Imagine Scientific, Inc. | Monochromatic X-ray methods and apparatus |
| US12253480B2 (en) | 2014-06-24 | 2025-03-18 | Imagine Scientific, Inc. | Methods and apparatus for determining information regarding chemical composition using x-ray radiation |
| US11833369B2 (en) | 2017-05-19 | 2023-12-05 | Imagine Scientific, Inc. | Monochromatic x-ray imaging systems and methods |
| US11744536B2 (en) | 2018-02-09 | 2023-09-05 | Imagine Scientific, Inc. | Monochromatic x-ray imaging systems and methods |
| US12521076B2 (en) | 2018-02-09 | 2026-01-13 | Imagine Scientific, Inc. | Monochromatic x-ray imaging systems and methods |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1627409A1 (en) | 2006-02-22 |
| EP1627409B1 (en) | 2008-09-03 |
| ATE407446T1 (en) | 2008-09-15 |
| US20080069305A1 (en) | 2008-03-20 |
| CN1791960A (en) | 2006-06-21 |
| US7567650B2 (en) | 2009-07-28 |
| DE602004016320D1 (en) | 2008-10-16 |
| JP2007503703A (en) | 2007-02-22 |
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