WO2005014639A3 - Periodic antimicrobial peptides - Google Patents

Periodic antimicrobial peptides Download PDF

Info

Publication number
WO2005014639A3
WO2005014639A3 PCT/US2004/005431 US2004005431W WO2005014639A3 WO 2005014639 A3 WO2005014639 A3 WO 2005014639A3 US 2004005431 W US2004005431 W US 2004005431W WO 2005014639 A3 WO2005014639 A3 WO 2005014639A3
Authority
WO
WIPO (PCT)
Prior art keywords
periodic
peptides
antimicrobial peptides
residues
polymerizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/005431
Other languages
French (fr)
Other versions
WO2005014639A2 (en
Inventor
Robert M Strom
Philip J Brondsema
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dow Global Technologies LLC
Original Assignee
Dow Global Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Global Technologies LLC filed Critical Dow Global Technologies LLC
Priority to EP04775797A priority Critical patent/EP1599499A2/en
Publication of WO2005014639A2 publication Critical patent/WO2005014639A2/en
Publication of WO2005014639A3 publication Critical patent/WO2005014639A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

One embodiment of the invention comprises a method of producing periodic peptides, which can have antimicrobial uses, and further comprises the peptides themselves. A preferred method comprises the synthesis of simple periodic peptides made from polymerizing identical monomer units of four or fewer amino acids, wherein the minimum length of active peptide is 15 or 16 residues and wherein the minimum percentage of cationic residues is at least 25%.
PCT/US2004/005431 2003-02-24 2004-02-24 Periodic antimicrobial peptides Ceased WO2005014639A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP04775797A EP1599499A2 (en) 2003-02-24 2004-02-24 Periodic antimicrobial peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37330603A 2003-02-24 2003-02-24
US10/373,306 2003-02-24

Publications (2)

Publication Number Publication Date
WO2005014639A2 WO2005014639A2 (en) 2005-02-17
WO2005014639A3 true WO2005014639A3 (en) 2005-07-07

Family

ID=34134967

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/005431 Ceased WO2005014639A2 (en) 2003-02-24 2004-02-24 Periodic antimicrobial peptides

Country Status (3)

Country Link
EP (1) EP1599499A2 (en)
CN (1) CN1894277A (en)
WO (1) WO2005014639A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9453251B2 (en) 2002-10-08 2016-09-27 Pfenex Inc. Expression of mammalian proteins in Pseudomonas fluorescens
US7928290B2 (en) 2004-02-27 2011-04-19 Dow Agrosciences Llc Viral capsid fusion peptide expressing plant cells
BRPI0513826A2 (en) 2004-07-26 2010-06-22 Dow Global Technologies Inc process for improved protein expression through strain engineering
US9580719B2 (en) 2007-04-27 2017-02-28 Pfenex, Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
US9394571B2 (en) 2007-04-27 2016-07-19 Pfenex Inc. Method for rapidly screening microbial hosts to identify certain strains with improved yield and/or quality in the expression of heterologous proteins
KR101863136B1 (en) 2008-01-24 2018-05-31 에스퍼란스 파마슈티컬스, 인코포레이티드 Lytic domain fusion constructs and methods of making and using same
IL238323B2 (en) 2012-10-30 2023-11-01 Esperance Pharmaceuticals Inc Antibody/drug conjugates and methods of use
JP6362878B2 (en) * 2013-03-12 2018-07-25 国立研究開発法人農業・食品産業技術総合研究機構 Fusion protein containing modified peptide repeat peptide and silk fiber containing the fusion protein
GB2522412A (en) * 2014-01-22 2015-07-29 Agency Science Tech & Res Antimicrobial peptidomimetics
CA2962951A1 (en) 2014-10-01 2016-04-07 Plant Health Care, Inc. Hypersensitive response elicitor peptides and use thereof
KR20170080579A (en) 2014-10-01 2017-07-10 플랜트 헬스 케어, 인코포레이티드 Elicitor peptides having disrupted hypersensitive response box and use thereof
CN107337713B (en) * 2016-05-03 2022-05-13 上海医药工业研究院 Antibacterial peptides and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789542A (en) * 1994-04-22 1998-08-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Amphipathic peptides
US6448391B1 (en) * 1994-07-22 2002-09-10 The United States Of America As Represented By The Secretary Of Agriculture Ubiquitin-lytic peptide gene promoter

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5789542A (en) * 1994-04-22 1998-08-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Amphipathic peptides
US6448391B1 (en) * 1994-07-22 2002-09-10 The United States Of America As Represented By The Secretary Of Agriculture Ubiquitin-lytic peptide gene promoter

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ARLOTTI J A ET AL: "Efficacy of a synthetic lytic peptide in the treatment of prostate cancer", UROLOGIC ONCOLOGY 2001 UNITED STATES, vol. 6, no. 3, 2001, pages 97 - 102, XP002311579, ISSN: 1078-1439 *
JAVADPOUR MARYAM M ET AL: "De novo antimicrobial peptides with low mammalian cell toxicity", BIOSIS, 1 January 1996 (1996-01-01), XP002164830 *
MA JIA ET AL: "Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro", JOURNAL OF VIROLOGY, vol. 76, no. 19, October 2002 (2002-10-01), pages 9952 - 9961, XP002311578, ISSN: 0022-538X *
NIIDOME T ET AL: "REQUIRED STRUCTURE OF CATIONIC PEPTIDE FOR OLIGONUCLEOTIDE-BINDING AND DELIVERING INTO CELLS", JOURNAL OF PEPTIDE SCIENCE, JOHN WILEY AND SONS LTD, GB, vol. 6, no. 6, 2000, pages 271 - 279, XP008028278, ISSN: 1075-2617 *

Also Published As

Publication number Publication date
CN1894277A (en) 2007-01-10
EP1599499A2 (en) 2005-11-30
WO2005014639A2 (en) 2005-02-17

Similar Documents

Publication Publication Date Title
WO2005014639A3 (en) Periodic antimicrobial peptides
WO2002090503A3 (en) Anti-microbial peptides and compositions
WO2003054152A3 (en) Novel nucleic acids and polypeptides
WO2002070539A3 (en) Novel nucleic acids and polypeptides
WO2003023013A3 (en) Novel nucleic acids and polypeptides
WO2002081731A3 (en) Novel nucleic acids and polypeptides
WO2006014570A3 (en) Purified amphilic peptide compositions and uses thereof
AU8701501A (en) Elastomeric functional biodegradable copolyester amides and copolyester urethanes
CA2449244A1 (en) Negatively charged amphiphilic block copolymer as drug carrier and complex thereof with positively charged drug
HK1051543A1 (en) Nogo receptor-mediated blockade of axonal growth
AU2002349190A1 (en) Process of preparation of formulations of the peptide angiotensin-(1-7) and its analogues, agonistic and antagonists using cyclodextrins, lipossomes and biodegradable polymers and/or mixtures and products thereof
EP1652862A8 (en) Deproteinized natural rubber, its composition and use thereof
WO2003029271A3 (en) Novel nucleic acids and polypeptides
WO2002059143A3 (en) Therapeutic peptides for demyelinating conditions
EP2314604A3 (en) Nucleic acids coding for adhesion factors of group B streptococcus, adhesion factors of group B streptococcus and further uses thereof
WO2004052773A3 (en) Peptide nanostructures, methods for their preparation and use
WO2002072616A3 (en) Transfection complexes
WO2005006938A3 (en) Anti-microbial medical implants and uses thereof
WO2005058959A3 (en) Treatment of viral infections
WO2003072154A8 (en) Composition and method for coating medical devices
WO2002095049A3 (en) Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
EP1790655A3 (en) Biologically active peptides
WO2001053347A3 (en) Nphs2 gene involved in the cortico-resistant neprhotic syndrome, protein encoded by said gene and diagnostic and therapeutic uses
WO2003006671A3 (en) Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
GB0229151D0 (en) Product and method

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DPEN Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed from 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2004775797

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2006508810

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 20048102993

Country of ref document: CN

WWP Wipo information: published in national office

Ref document number: 2004775797

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2004775797

Country of ref document: EP