WO2005017191A3 - Enzymatic diagnostic test for sars and other viral diseases - Google Patents

Enzymatic diagnostic test for sars and other viral diseases Download PDF

Info

Publication number
WO2005017191A3
WO2005017191A3 PCT/US2004/019897 US2004019897W WO2005017191A3 WO 2005017191 A3 WO2005017191 A3 WO 2005017191A3 US 2004019897 W US2004019897 W US 2004019897W WO 2005017191 A3 WO2005017191 A3 WO 2005017191A3
Authority
WO
WIPO (PCT)
Prior art keywords
sars
diagnostic test
viral diseases
enzymatic diagnostic
enzymatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/019897
Other languages
French (fr)
Other versions
WO2005017191A2 (en
Inventor
Dorit Arad
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NLCPHARMA Inc
Original Assignee
NLCPHARMA Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NLCPHARMA Inc filed Critical NLCPHARMA Inc
Priority to JP2006517512A priority Critical patent/JP2007524387A/en
Priority to CA002530401A priority patent/CA2530401A1/en
Priority to EP04785952A priority patent/EP1644515A2/en
Priority to AU2004265603A priority patent/AU2004265603B2/en
Publication of WO2005017191A2 publication Critical patent/WO2005017191A2/en
Publication of WO2005017191A3 publication Critical patent/WO2005017191A3/en
Priority to IL172789A priority patent/IL172789A0/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/085—Picornaviridae, e.g. coxsackie virus, echovirus, enterovirus
    • G01N2333/095—Rhinovirus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention is directed towards methods, compositions and kits for testing for a virus in a sample. The methods determine the presence of a viral enzyme by contacting the sample with a peptidal compound capable of being cleaved by the viral enzyme to form peptidal compound fragments. Detection of a peptidal compound fragment confirms the presence of the virus.
PCT/US2004/019897 2003-06-23 2004-06-22 Enzymatic diagnostic test for sars and other viral diseases Ceased WO2005017191A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2006517512A JP2007524387A (en) 2003-06-23 2004-06-22 Diagnostic test method for SARS and other viral diseases using enzymes
CA002530401A CA2530401A1 (en) 2003-06-23 2004-06-22 Enzymatic diagnostic test for sars and other viral diseases
EP04785952A EP1644515A2 (en) 2003-06-23 2004-06-22 Enzymatic diagnostic test for sars and other viral diseases
AU2004265603A AU2004265603B2 (en) 2003-06-23 2004-06-22 Enzymatic diagnostic test for SARS and other viral diseases
IL172789A IL172789A0 (en) 2003-06-23 2005-12-22 Enzymatic diagnostic test for sars and other viral diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48060503P 2003-06-23 2003-06-23
US60/480,605 2003-06-23

Publications (2)

Publication Number Publication Date
WO2005017191A2 WO2005017191A2 (en) 2005-02-24
WO2005017191A3 true WO2005017191A3 (en) 2005-08-18

Family

ID=34193032

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/019897 Ceased WO2005017191A2 (en) 2003-06-23 2004-06-22 Enzymatic diagnostic test for sars and other viral diseases

Country Status (8)

Country Link
US (2) US7635557B2 (en)
EP (1) EP1644515A2 (en)
JP (1) JP2007524387A (en)
CN (1) CN100549183C (en)
AU (1) AU2004265603B2 (en)
CA (1) CA2530401A1 (en)
IL (1) IL172789A0 (en)
WO (1) WO2005017191A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005528887A (en) 2002-01-31 2005-09-29 エクスプレッシブ コンストラクツ，インコーポレイテッド Microbial detection method
CA2530401A1 (en) * 2003-06-23 2005-02-24 Nlcpharma Inc. Enzymatic diagnostic test for sars and other viral diseases
US7393638B2 (en) * 2003-07-01 2008-07-01 Asiagen Corporation Assay system and methods for detecting SARS-CV
AU2006268140A1 (en) * 2005-07-13 2007-01-18 Expressive Constructs, Inc. Substrates, sensors, and methods for assessing conditions in females
WO2010011002A1 (en) 2008-07-23 2010-01-28 Industry-Academic Cooperation Foundation Gyeongsang National University Method and system for diagnosing virus
EP2315842A2 (en) * 2008-07-28 2011-05-04 Dorit Arad Methods and compositions for detection of a pathogen, disease, medical condition, or biomarker thereof
US20150355147A1 (en) * 2014-06-06 2015-12-10 Biogénesis Bagó Uruguay S.A. High throughput quantification and characterization of foot and mouth disease virus and products thereof
CN115335532A (en) * 2020-02-09 2022-11-11 Nlc制药有限公司 SARS-COV-2 quick detection test
CN115362262A (en) * 2020-03-30 2022-11-18 奥里基诺G有限公司 Diagnostic peptides for use in methods, kits and systems for diagnosing viral infections
US11603552B2 (en) 2020-07-20 2023-03-14 Mesa Photonics, LLC Method for pathogen identification

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748116A (en) * 1980-08-25 1988-05-31 Kabivitrum Ab Peptide substrates for determination of protease activity
US4952493A (en) * 1985-01-11 1990-08-28 E. I. Du Pont De Nemours And Company Peptide substrates for detecting virus-specified protease activity
US6127139A (en) * 1996-01-04 2000-10-03 Nederlands Organisatle Voor Toegepast-Natuurwetenschappelijk Onderzoek (Tno) Method for assaying proteolytic enzymes using fluorescence-quenched substrates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL174591C (en) * 1973-02-09 1984-07-02 Philips Nv DISC REGISTRATION CARRIER BODY.
WO1995017672A1 (en) * 1993-12-23 1995-06-29 Tropix, Inc. Chemiluminescent energy transfer assays
US5591591A (en) * 1995-02-09 1997-01-07 Tropix, Inc. Dioxetane compounds for the chemiluminescent detection of proteases, methods of use and kits therefore
US6037137A (en) * 1997-02-20 2000-03-14 Oncoimmunin, Inc. Fluorogenic peptides for the detection of protease activity
US6243980B1 (en) * 1997-03-07 2001-06-12 Tropix, Inc. Protease inhibitor assay
CA2530401A1 (en) 2003-06-23 2005-02-24 Nlcpharma Inc. Enzymatic diagnostic test for sars and other viral diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4748116A (en) * 1980-08-25 1988-05-31 Kabivitrum Ab Peptide substrates for determination of protease activity
US4952493A (en) * 1985-01-11 1990-08-28 E. I. Du Pont De Nemours And Company Peptide substrates for detecting virus-specified protease activity
US6127139A (en) * 1996-01-04 2000-10-03 Nederlands Organisatle Voor Toegepast-Natuurwetenschappelijk Onderzoek (Tno) Method for assaying proteolytic enzymes using fluorescence-quenched substrates

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANAND KANCHAN ET AL: "Coronavirus main proteinase (3CLpro) structure: Basis for design of anti-SARS drugs", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 300, no. 5626, 13 June 2003 (2003-06-13), pages 1763 - 1767, XP002291115, ISSN: 0036-8075 *
KSIAZEK T G ET AL: "A novel coronavirus associated with severe acute respiratory syndrome", NEW ENGLAND JOURNAL OF MEDICINE, MASSACHUSETTS MEDICAL SOCIETY, BOSTON, MA, US, vol. 348, no. 20, 15 May 2003 (2003-05-15), pages 1953 - 1966, XP002276003, ISSN: 1533-4406 *
MARRA M A ET AL: "The genome sequence of the SARS-associated coronavirus", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 300, no. 5624, 30 May 2003 (2003-05-30), pages 1399 - 1404, XP002269483, ISSN: 0036-8075 *
ROTA P A ET AL: "Characterization of a novel coronavirus associated with severe acute respiratory syndrome", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 300, no. 5624, 30 May 2003 (2003-05-30), pages 1394 - 1399, XP002269482, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
CN1860240A (en) 2006-11-08
US7635557B2 (en) 2009-12-22
US20100143888A1 (en) 2010-06-10
AU2004265603B2 (en) 2009-11-26
WO2005017191A2 (en) 2005-02-24
CN100549183C (en) 2009-10-14
IL172789A0 (en) 2006-06-11
US20050048473A1 (en) 2005-03-03
AU2004265603A1 (en) 2005-02-24
EP1644515A2 (en) 2006-04-12
JP2007524387A (en) 2007-08-30
CA2530401A1 (en) 2005-02-24

Similar Documents

Publication Publication Date Title
WO2021156878A3 (en) Rapid detection test for sars-cov-2
DE602007011937D1 (en) PEPTIDANT BODY DETECTION AND APPLICATION FOR SPECIMEN PREPARATION FOR MASS SPECTROMETRY
WO2005032487A3 (en) Angiotensin-converting enzyme-2 as a receptor for the sars coronavirus
WO2007047796A3 (en) Tissue-and serum-derived glycoproteins and methods of their use
WO2002068683A3 (en) Circular probe amplification (cpa) using energy-transfer primers
WO2004085650A8 (en) A high-troughput diagnostic assay for the human virus causing severe acute respiratory syndrome (sars)
WO2008021290A3 (en) Organ-specific proteins and methods of their use
WO2008038000A8 (en) Diagnostic method for detecting or monitoring cancer
IL188460A0 (en) Diagnostic methods and compositions for diagnosing and treating influenza
WO2006128138A3 (en) Biodetection by nucleic acid-templated chemistry
ATE511645T1 (en) TEST METHOD FOR DETECTING ANTIBODIES AGAINST LYSOSOME ENZYMES
WO2005017191A3 (en) Enzymatic diagnostic test for sars and other viral diseases
WO2005042771A3 (en) Colorimetric substrates, colorimetric sensors, and methods of use
NO20030495D0 (en) Peptides presented by cells
WO2007035766A3 (en) Biomarker for prostate cancer
WO2006002243A3 (en) Methods of oligosaccharide profiling for the detection of cancer
WO2005087951A3 (en) Reagents, methods and kits for use in deactivating nucleic acids
WO2005118836A3 (en) Hif prolyl hydroxylase activity assay
WO2007132120A3 (en) Procedure and methods for detecting alzheimer's disease
WO2006077102A3 (en) Method for the detection of hpv and probes, primers and kits
WO2006031644A3 (en) Immobilized probes and methods of detecting conformationally altered prion proteins
PL1904627T3 (en) Method for the preparation of prrs virus and proteins of and diagnostic test kits for detecting them
WO2005051313A3 (en) Methods and reagents for treating, preventing and diagnosing bunyavirus infection
WO2008003024A3 (en) Method and composition for diagnosing endometrial cancer
WO2005067643A8 (en) Determination of hepatitis c virus genotype

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200480024253.7

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NA NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
ENP Entry into the national phase

Ref document number: 2530401

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 172789

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2006517512

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2004265603

Country of ref document: AU

Ref document number: 2004785952

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 236/CHENP/2006

Country of ref document: IN

Ref document number: 0236/CHENP/2006

Country of ref document: IN

ENP Entry into the national phase

Ref document number: 2004265603

Country of ref document: AU

Date of ref document: 20040622

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004785952

Country of ref document: EP