WO2005026204A3 - Synthetic antimicrobial polypeptides - Google Patents

Synthetic antimicrobial polypeptides Download PDF

Info

Publication number
WO2005026204A3
WO2005026204A3 PCT/DK2004/000606 DK2004000606W WO2005026204A3 WO 2005026204 A3 WO2005026204 A3 WO 2005026204A3 DK 2004000606 W DK2004000606 W DK 2004000606W WO 2005026204 A3 WO2005026204 A3 WO 2005026204A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
synthetic antimicrobial
antimicrobial polypeptides
nucleic acid
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DK2004/000606
Other languages
French (fr)
Other versions
WO2005026204A2 (en
Inventor
Hans-Henrik Kristen Hoegenhaug
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2006525632A priority Critical patent/JP2007527228A/en
Priority to AU2004272170A priority patent/AU2004272170B2/en
Priority to EP04762826A priority patent/EP1664107A2/en
Priority to CA2538085A priority patent/CA2538085C/en
Priority to NZ545815A priority patent/NZ545815A/en
Priority to BRPI0414253-5A priority patent/BRPI0414253A/en
Application filed by Novozymes AS filed Critical Novozymes AS
Priority to US11/030,232 priority patent/US7250398B2/en
Publication of WO2005026204A2 publication Critical patent/WO2005026204A2/en
Publication of WO2005026204A3 publication Critical patent/WO2005026204A3/en
Priority to IL174092A priority patent/IL174092A/en
Anticipated expiration legal-status Critical
Priority to US11/766,178 priority patent/US7833967B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4723—Cationic antimicrobial peptides, e.g. defensins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Detergent Compositions (AREA)

Abstract

The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.
PCT/DK2004/000606 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides Ceased WO2005026204A2 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
AU2004272170A AU2004272170B2 (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides
EP04762826A EP1664107A2 (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides
CA2538085A CA2538085C (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides
NZ545815A NZ545815A (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides
BRPI0414253-5A BRPI0414253A (en) 2003-09-12 2004-09-13 polypeptide, polynucleotide, nucleic acid construct, recombinant expression vector, recombinant host cell, methods for producing a polypeptide, and for killing or inhibiting microbial cell growth, composition, use of a polypeptide, transgenic plant, plant part or cell vegetable and animal feed additive
JP2006525632A JP2007527228A (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptide
US11/030,232 US7250398B2 (en) 2003-09-12 2005-01-06 Synthetic antimicrobial polypeptides
IL174092A IL174092A (en) 2003-09-12 2006-03-02 Synthetic antimicrobial polypeptides
US11/766,178 US7833967B2 (en) 2003-09-12 2007-06-21 Synthetic antimicrobial polypeptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200301324 2003-09-12
DKPA200301324 2003-09-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/030,232 Continuation US7250398B2 (en) 2003-09-12 2005-01-06 Synthetic antimicrobial polypeptides

Publications (2)

Publication Number Publication Date
WO2005026204A2 WO2005026204A2 (en) 2005-03-24
WO2005026204A3 true WO2005026204A3 (en) 2005-04-28

Family

ID=34306686

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2004/000606 Ceased WO2005026204A2 (en) 2003-09-12 2004-09-13 Synthetic antimicrobial polypeptides

Country Status (10)

Country Link
EP (1) EP1664107A2 (en)
JP (1) JP2007527228A (en)
CN (2) CN1878791A (en)
AU (1) AU2004272170B2 (en)
BR (1) BRPI0414253A (en)
CA (1) CA2538085C (en)
IL (1) IL174092A (en)
NZ (1) NZ545815A (en)
WO (1) WO2005026204A2 (en)
ZA (1) ZA200601999B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO20041892D0 (en) * 2004-05-07 2004-05-07 Uni I Tromso Novel crustacean proline-rich peptides
KR101410685B1 (en) 2005-10-04 2014-06-24 솔리제닉스, 인크. Novel peptides for treating and preventing immune-related disorders, including treating and preventing infection by modulating innate immunity
JP2012100639A (en) * 2010-11-09 2012-05-31 Kai:Kk Method of washing, application and antibacterial treatment using enzyme treatment solution
CN111233979B (en) * 2020-02-19 2026-04-03 四川大学华西医院 A Gemini Amphiphilic Short Peptide and Its Application as a Hydrophobic Drug Carrier
CN119285743B (en) * 2024-11-18 2025-06-24 东北农业大学 A kind of antimicrobial peptide derived from pig PR-39 and its preparation method and application

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992022578A1 (en) * 1991-06-14 1992-12-23 Lee Jong Youn Novel polypeptides and their use
EP0665239A1 (en) * 1994-01-26 1995-08-02 Consiglio Nazionale Delle Ricerche Peptide derivatives of bactenecin endowed with antibacterial activity
US5830993A (en) * 1995-04-10 1998-11-03 Kansas State University Research Foundation Synthetic antimicrobial peptide

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992022578A1 (en) * 1991-06-14 1992-12-23 Lee Jong Youn Novel polypeptides and their use
EP0665239A1 (en) * 1994-01-26 1995-08-02 Consiglio Nazionale Delle Ricerche Peptide derivatives of bactenecin endowed with antibacterial activity
US5830993A (en) * 1995-04-10 1998-11-03 Kansas State University Research Foundation Synthetic antimicrobial peptide

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
ANDERSON R C ET AL: "Isolation and characterisation of proline/arginine-rich cathelicidin peptides from ovine neutrophils", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 312, no. 4, 26 December 2003 (2003-12-26), pages 1139 - 1146, XP004476395, ISSN: 0006-291X *
HUTTNER K M ET AL: "Localization and genomic organization of sheep antimicrobial peptide genes", GENE: AN INTERNATIONAL JOURNAL ON GENES AND GENOMES, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 206, no. 1, 5 January 1998 (1998-01-05), pages 85 - 91, XP004102876, ISSN: 0378-1119 *
NIIDOME E.A.: "Antibacterial activity of Arg/Pro rich bactenecin 5 model peptides and their interaction with phospholipid membranes", BULL.CHEM.SOC.JPN, vol. 73, 2000, pages 1397 - 1402, XP008028277 *
NIIDOME TAKURO ET AL: "Structure and property of model peptides of proline/arginine-rich region in bactenecin 5", JOURNAL OF PEPTIDE RESEARCH, vol. 51, no. 5, May 1998 (1998-05-01), pages 337 - 345, XP000739868, ISSN: 1397-002X *
RAJ P A ET AL: "Delineation of an active fragment and poly(L-proline) II conformation for candidacidal activity of bactenecin 5.", BIOCHEMISTRY. UNITED STATES 9 APR 1996, vol. 35, no. 14, 9 April 1996 (1996-04-09), pages 4314 - 4325, XP002272963, ISSN: 0006-2960 *
SHAMOVA O ET AL: "Purification and properties of proline-rich antimicrobial peptides from sheep and goat leukocytes.", INFECTION AND IMMUNITY. AUG 1999, vol. 67, no. 8, August 1999 (1999-08-01), pages 4106 - 4111, XP002318719, ISSN: 0019-9567 *

Also Published As

Publication number Publication date
JP2007527228A (en) 2007-09-27
CN101113173A (en) 2008-01-30
CN1878791A (en) 2006-12-13
WO2005026204A2 (en) 2005-03-24
IL174092A0 (en) 2006-08-01
IL174092A (en) 2010-11-30
AU2004272170A1 (en) 2005-03-24
CA2538085C (en) 2011-03-15
AU2004272170B2 (en) 2011-04-07
BRPI0414253A (en) 2006-11-21
CA2538085A1 (en) 2005-03-24
EP1664107A2 (en) 2006-06-07
NZ545815A (en) 2009-11-27
ZA200601999B (en) 2007-02-28

Similar Documents

Publication Publication Date Title
IL161769A0 (en) Anbtimicrobial polypeptides from pseudoplectania nigrella
AU2003291962A1 (en) Polypeptides having cellobiohydrolase ii activity and polynucleotides encoding same
WO2006078256A3 (en) Polypeptides having xylanase activity and polynucleotides encoding same
WO2006039541A3 (en) Polypeptides having lipase activity and polynucleotides encoding same
EP2277997A3 (en) Polypeptides having cellobiohydrolase I activity and polynucleotides encoding same
EP2267000A3 (en) Antimicrobial polypeptides
WO2007019442A3 (en) Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2005074647A3 (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2006074435A3 (en) Polypeptides having cellobiohydrlase activity and polynucleotides encoding same
WO2005074656A3 (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2336309A3 (en) Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2007115201A3 (en) Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2006047469A8 (en) Polypeptides having lipase activity and polynucleotides encoding same
TW200740841A (en) Polypeptides having antimicrobial activity and polynucleotides encoding same
WO2005059155A3 (en) Method for the insolation of methionine from a fermentation supernatant
TW200510460A (en) Antimicrobial polypeptides
WO2006116682A3 (en) Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2004108757A3 (en) Antimicrobial polypeptides
TW200621284A (en) Polypeptides having antimicrobial activity and polynucleotides encoding same
WO2006005032A3 (en) Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
TW200734350A (en) Polypeptides having antimicrobial activity and polynucleotides encoding same
WO2006097110A3 (en) Polypeptides having antimicrobial activity and polynucleotides encoding same
WO2006014490A3 (en) Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
WO2006053565A3 (en) Polypeptides having antimicrobial activity and polynucleotides encoding same
WO2004050696A3 (en) Antimicrobial polypeptide isolated from rhizomucor pusillus

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200480033242.5

Country of ref document: CN

WWE Wipo information: entry into national phase

Ref document number: 11030232

Country of ref document: US

ENP Entry into the national phase

Ref document number: 2005030232

Country of ref document: US

Kind code of ref document: A

AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BW BY BZ CA CH CN CO CR CU CZ DK DM DZ EC EE EG ES FI GB GD GE GM HR HU ID IL IN IS JP KE KG KP KZ LC LK LR LS LT LU LV MA MD MK MN MW MX MZ NA NI NO NZ PG PH PL PT RO RU SC SD SE SG SK SY TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SZ TZ UG ZM ZW AM AZ BY KG MD RU TJ TM AT BE BG CH CY DE DK EE ES FI FR GB GR HU IE IT MC NL PL PT RO SE SI SK TR BF CF CG CI CM GA GN GQ GW ML MR SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 174092

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2004762826

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2538085

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2004272170

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 545815

Country of ref document: NZ

Ref document number: 2006525632

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 861/CHENP/2006

Country of ref document: IN

WWE Wipo information: entry into national phase

Ref document number: 2006/01999

Country of ref document: ZA

Ref document number: 200601999

Country of ref document: ZA

ENP Entry into the national phase

Ref document number: 2004272170

Country of ref document: AU

Date of ref document: 20040913

Kind code of ref document: A

WWP Wipo information: published in national office

Ref document number: 2004272170

Country of ref document: AU

WWP Wipo information: published in national office

Ref document number: 2004762826

Country of ref document: EP

ENP Entry into the national phase

Ref document number: PI0414253

Country of ref document: BR