WO2005042771A3 - Colorimetric substrates, colorimetric sensors, and methods of use - Google Patents

Colorimetric substrates, colorimetric sensors, and methods of use Download PDF

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Publication number
WO2005042771A3
WO2005042771A3 PCT/US2004/036469 US2004036469W WO2005042771A3 WO 2005042771 A3 WO2005042771 A3 WO 2005042771A3 US 2004036469 W US2004036469 W US 2004036469W WO 2005042771 A3 WO2005042771 A3 WO 2005042771A3
Authority
WO
WIPO (PCT)
Prior art keywords
colorimetric
methods
substrate
protein
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2004/036469
Other languages
French (fr)
Other versions
WO2005042771A2 (en
Inventor
Mitchell C Sanders
Gerard J Colpas
Diane L Ellis-Busby
Jennifer M Havard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ethicon Inc
ECI Biotech Inc
Original Assignee
Ethicon Inc
ECI Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US10/576,634 priority Critical patent/US8927204B2/en
Priority to AU2004286338A priority patent/AU2004286338A1/en
Priority to JP2006538437A priority patent/JP4767863B2/en
Priority to AT04817523T priority patent/ATE432358T1/en
Priority to DE602004021281T priority patent/DE602004021281D1/en
Priority to CA002557623A priority patent/CA2557623A1/en
Application filed by Ethicon Inc, ECI Biotech Inc filed Critical Ethicon Inc
Priority to EP04817523A priority patent/EP1687439B1/en
Publication of WO2005042771A2 publication Critical patent/WO2005042771A2/en
Publication of WO2005042771A3 publication Critical patent/WO2005042771A3/en
Anticipated expiration legal-status Critical
Priority to AU2008212057A priority patent/AU2008212057B2/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Spectrometry And Color Measurement (AREA)

Abstract

Described herein is a substrate comprising at least one colorimetric component attached to a peptide, as well as methods for detecting a modification of said substrate. Also described are methods of detecting the presence or absence of a protein, for example, a protein produced by a microorganism, by contacting a substrate with a sample. If the sample contains the protein of interest, the substrate is modified and a visible color change results, indicating the presence or absence of the protein in the sample. The present invention also features biosensors and kits for detecting the presence or absence of microorganisms and/or proteins in a sample.
PCT/US2004/036469 2003-11-03 2004-11-03 Colorimetric substrates, colorimetric sensors, and methods of use Ceased WO2005042771A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU2004286338A AU2004286338A1 (en) 2003-11-03 2004-11-03 Colorimetric substrates, colorimetric sensors, and methods of use
JP2006538437A JP4767863B2 (en) 2003-11-03 2004-11-03 Colorimetric substrate, colorimetric sensor, and method of use
AT04817523T ATE432358T1 (en) 2003-11-03 2004-11-03 COLORIMETRIC SUBSTRATES, COLORIMETRIC SENSORS AND METHODS OF USE
DE602004021281T DE602004021281D1 (en) 2003-11-03 2004-11-03 COLORIMETRIC SUBSTRATES, COLORIMETRIC SENSORS AND METHOD OF USE
CA002557623A CA2557623A1 (en) 2003-11-03 2004-11-03 Detection of a microorganism by detecting modification of a peptide substrate and a biosensor for same
US10/576,634 US8927204B2 (en) 2003-11-03 2004-11-03 Colorimetric substrates, colorimetric sensors, and methods of use
EP04817523A EP1687439B1 (en) 2003-11-03 2004-11-03 Colorimetric substrates, colorimetric sensors, and methods of use
AU2008212057A AU2008212057B2 (en) 2003-11-03 2008-09-08 Colorimetric substrates, colorimetric sensors, and methods of use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US51668803P 2003-11-03 2003-11-03
US60/516,688 2003-11-03
US57850204P 2004-06-09 2004-06-09
US60/578,502 2004-06-09

Publications (2)

Publication Number Publication Date
WO2005042771A2 WO2005042771A2 (en) 2005-05-12
WO2005042771A3 true WO2005042771A3 (en) 2005-08-04

Family

ID=34556192

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2004/036469 Ceased WO2005042771A2 (en) 2003-11-03 2004-11-03 Colorimetric substrates, colorimetric sensors, and methods of use

Country Status (9)

Country Link
US (1) US8927204B2 (en)
EP (1) EP1687439B1 (en)
JP (1) JP4767863B2 (en)
AT (1) ATE432358T1 (en)
AU (2) AU2004286338A1 (en)
CA (1) CA2557623A1 (en)
DE (1) DE602004021281D1 (en)
ES (1) ES2325923T3 (en)
WO (1) WO2005042771A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003063693A2 (en) * 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms
US20040062682A1 (en) 2002-09-30 2004-04-01 Rakow Neal Anthony Colorimetric sensor
US7449146B2 (en) 2002-09-30 2008-11-11 3M Innovative Properties Company Colorimetric sensor
US8124370B2 (en) 2003-01-31 2012-02-28 Systagenix Wound Management (Us), Inc. Cationic anti-microbial peptides and methods of use thereof
ES2357547T3 (en) 2003-09-02 2011-04-27 Systagenix Wound Management Ip Co. Bv. SIGNAL AMPLIFICATION USING A SYNTHETIC ZYMOGEN.
CA2557612C (en) 2003-11-03 2014-06-17 Ethicon, Inc. Methods, peptides and biosensors useful for detecting a broad spectrum of bacteria
DE602004021281D1 (en) 2003-11-03 2009-07-09 Ethicon Inc COLORIMETRIC SUBSTRATES, COLORIMETRIC SENSORS AND METHOD OF USE
US20070128589A1 (en) * 2005-07-13 2007-06-07 Sanders Mitchell C Substrates, sensors, and methods for assessing conditions in females
US7767143B2 (en) * 2006-06-27 2010-08-03 3M Innovative Properties Company Colorimetric sensors
US7763442B2 (en) 2006-08-31 2010-07-27 Kimberly-Clark Worldwide, Inc. Method for detecting candida on skin
US7531319B2 (en) 2006-08-31 2009-05-12 Kimberly-Clark Worldwide, Inc. Array for rapid detection of a microorganism
JP2010532416A (en) * 2007-06-29 2010-10-07 スリーエム イノベイティブ プロパティズ カンパニー Functional polymers with pendant color indicators
EP2685999A4 (en) 2011-03-18 2015-07-15 Univ Duke PEPTIDES FOR SUPPRESSION OF INFLAMMATION
US9303063B2 (en) 2011-03-18 2016-04-05 Duke University Peptide compounds for suppressing inflammation
US10226212B2 (en) 2012-04-12 2019-03-12 Elwha Llc Appurtenances to cavity wound dressings
US10158928B2 (en) 2012-04-12 2018-12-18 Elwha Llc Appurtenances for reporting information regarding wound dressings
US9024751B2 (en) 2012-04-12 2015-05-05 Elwha Llc Dormant to active appurtenances for reporting information regarding wound dressings
US9084530B2 (en) 2012-04-12 2015-07-21 Elwha Llc Computational methods and systems for reporting information regarding appurtenances to wound dressings
US10130518B2 (en) 2012-04-12 2018-11-20 Elwha Llc Appurtenances including sensors for reporting information regarding wound dressings
US10265219B2 (en) 2012-04-12 2019-04-23 Elwha Llc Wound dressing monitoring systems including appurtenances for wound dressings
NL2010040C2 (en) * 2012-12-21 2014-06-24 Internat Inst For Diagnostic And Analitical Affairs B V Cleavable coating material having microbial functionality.
CN109310528B (en) * 2016-03-30 2021-07-20 康沃特克科技公司 Detection of microbial infections in wounds
AU2017243601A1 (en) * 2016-03-30 2018-11-22 Acib Gmbh Detecting microbial infection in wounds
US12140820B2 (en) 2021-05-04 2024-11-12 Khalifa University of Science and Technology Method of manufacturing contact lens for treating color vision deficiency
US11899289B2 (en) * 2021-05-04 2024-02-13 Khalifa University of Science and Technology Contact lens for treating color vision deficiency and method of manufacturing same

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038995A1 (en) * 1998-01-28 1999-08-05 Bio Merieux Use of indolamine derivatives for detecting micro-organism peptidase
WO2002006821A2 (en) * 2000-07-17 2002-01-24 Hansa Medical Ab Antimicrobial agent
WO2003063693A2 (en) * 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4242447A (en) * 1978-11-29 1980-12-30 Bioresearch Rapid detection of bacteria
EP0122028A1 (en) 1983-03-07 1984-10-17 E-Y Laboratories, Inc. Colorimetric assay for enzymes, diagnostic article therefor and a method for forming such article
US5302731A (en) * 1992-07-13 1994-04-12 Becton, Dickinson And Company Fluorescent pH indicators
US5798276A (en) * 1995-06-07 1998-08-25 Molecular Probes, Inc. Reactive derivatives of sulforhodamine 101 with enhanced hydrolytic stability
US5846737A (en) * 1996-07-26 1998-12-08 Molecular Probes, Inc. Conjugates of sulforhodamine fluorophores with enhanced fluorescence
JPH11178567A (en) 1997-12-22 1999-07-06 Bml:Kk Bacteria detection device
DE60122582T2 (en) * 2000-05-03 2007-10-04 Expressive Constructs, Inc., Worcester PROCESS FOR DETECTING LISTERIA MONOCYTOGENES
US20030096315A1 (en) * 2000-05-03 2003-05-22 Sanders Mitchell C. Device for detecting bacterial contamination and method of use
AU2004225575B2 (en) * 2003-01-31 2008-02-21 Ethicon, Inc. Method for detecting escherichia coli
US8124370B2 (en) * 2003-01-31 2012-02-28 Systagenix Wound Management (Us), Inc. Cationic anti-microbial peptides and methods of use thereof
ES2357547T3 (en) * 2003-09-02 2011-04-27 Systagenix Wound Management Ip Co. Bv. SIGNAL AMPLIFICATION USING A SYNTHETIC ZYMOGEN.
CA2557612C (en) * 2003-11-03 2014-06-17 Ethicon, Inc. Methods, peptides and biosensors useful for detecting a broad spectrum of bacteria
DE602004021281D1 (en) 2003-11-03 2009-07-09 Ethicon Inc COLORIMETRIC SUBSTRATES, COLORIMETRIC SENSORS AND METHOD OF USE

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999038995A1 (en) * 1998-01-28 1999-08-05 Bio Merieux Use of indolamine derivatives for detecting micro-organism peptidase
WO2002006821A2 (en) * 2000-07-17 2002-01-24 Hansa Medical Ab Antimicrobial agent
WO2003063693A2 (en) * 2002-01-31 2003-08-07 Expressive Constructs, Inc. Method for detecting microorganisms

Also Published As

Publication number Publication date
ATE432358T1 (en) 2009-06-15
EP1687439B1 (en) 2009-05-27
AU2008212057B2 (en) 2011-03-17
EP1687439A2 (en) 2006-08-09
AU2004286338A1 (en) 2005-05-12
WO2005042771A2 (en) 2005-05-12
ES2325923T3 (en) 2009-09-24
US20070269851A1 (en) 2007-11-22
CA2557623A1 (en) 2005-05-12
AU2008212057A1 (en) 2008-10-02
DE602004021281D1 (en) 2009-07-09
US8927204B2 (en) 2015-01-06
JP4767863B2 (en) 2011-09-07
JP2007513607A (en) 2007-05-31

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