WO2006034335A3 - Method of detecting cancer based on immune reaction to boris - Google Patents

Method of detecting cancer based on immune reaction to boris Download PDF

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Publication number
WO2006034335A3
WO2006034335A3 PCT/US2005/033796 US2005033796W WO2006034335A3 WO 2006034335 A3 WO2006034335 A3 WO 2006034335A3 US 2005033796 W US2005033796 W US 2005033796W WO 2006034335 A3 WO2006034335 A3 WO 2006034335A3
Authority
WO
WIPO (PCT)
Prior art keywords
boris
immune reaction
detecting cancer
cancer based
mammal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/033796
Other languages
French (fr)
Other versions
WO2006034335A2 (en
Inventor
Victor V Lobanenkov
Dmitri LOUKINOV
Ziedulla Abdullaev
Svetlana Pack
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Department of Health and Human Services
Original Assignee
United States Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Department of Health and Human Services filed Critical United States Department of Health and Human Services
Priority to EP05799643A priority Critical patent/EP1802972B1/en
Priority to US11/575,732 priority patent/US7785814B2/en
Priority to AT05799643T priority patent/ATE432469T1/en
Priority to DE602005014659T priority patent/DE602005014659D1/en
Publication of WO2006034335A2 publication Critical patent/WO2006034335A2/en
Publication of WO2006034335A3 publication Critical patent/WO2006034335A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57557—Immunoassay; Biospecific binding assay; Materials therefor for cancer of other specific parts of the body, e.g. brain

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

The invention provides a method of detecting a proliferative disease, such as a disease associated with the abnormal expression of BORIS, in a mammal comprising detecting antibodies to BORIS in a sample obtained from the mammal. The invention also provides BORIS polypeptides as well as compositions and kits comprising the BORIS polypeptides and methods of using the same. The invention further provides a method of inducing an immune response in a mammal using BORIS polypeptides.
PCT/US2005/033796 2004-09-21 2005-09-21 Method of detecting cancer based on immune reaction to boris Ceased WO2006034335A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP05799643A EP1802972B1 (en) 2004-09-21 2005-09-21 Method of detecting cancer based on immune reaction to boris
US11/575,732 US7785814B2 (en) 2004-09-21 2005-09-21 Method of detecting cancer based on immune reaction to BORIS
AT05799643T ATE432469T1 (en) 2004-09-21 2005-09-21 PROCESS BASED ON IMMUNE REACTION AGAINST BORIS FOR DETECTING CANCER
DE602005014659T DE602005014659D1 (en) 2004-09-21 2005-09-21 ON IMMUNE RESPONSE AGAINST BORIS BASED PROCEDURE FOR THE DETECTION OF CANCER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61179804P 2004-09-21 2004-09-21
US60/611,798 2004-09-21

Publications (2)

Publication Number Publication Date
WO2006034335A2 WO2006034335A2 (en) 2006-03-30
WO2006034335A3 true WO2006034335A3 (en) 2006-08-03

Family

ID=36090647

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/033796 Ceased WO2006034335A2 (en) 2004-09-21 2005-09-21 Method of detecting cancer based on immune reaction to boris

Country Status (6)

Country Link
US (1) US7785814B2 (en)
EP (1) EP1802972B1 (en)
AT (1) ATE432469T1 (en)
DE (1) DE602005014659D1 (en)
ES (1) ES2325866T3 (en)
WO (1) WO2006034335A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006082414A1 (en) * 2005-02-03 2006-08-10 Cancer Research Technology Limited Detection and diagnosis of cancer
DE102005024578A1 (en) * 2005-05-25 2006-11-30 Raumedic Ag Probe for measuring oxygen content in biological material comprises distal fiber section inclusive of distal end face along with dye enclosed by oxygen-penetrable, fluid-impenetrable membrane which in enclosed area provides gas space
US8206933B2 (en) 2006-08-31 2012-06-26 The United States Of America, As Represented By The Department Of Health And Human Services Boris isoforms and methods of detecting and treating disease
US10415094B2 (en) 2016-10-06 2019-09-17 HelicalHelp LLC Risk stratification method for a patient having a polymorphism
WO2020154654A1 (en) * 2019-01-25 2020-07-30 Mayo Foundation For Medical Education And Research Assessing and treating germ cell tumors and paraneoplastic autoimmunity
USD982375S1 (en) 2019-06-06 2023-04-04 Sharkninja Operating Llc Food preparation device

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003072799A2 (en) * 2002-02-22 2003-09-04 The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Brother of the regulator of imprinted sites (boris)
WO2005021029A2 (en) * 2003-08-25 2005-03-10 Agadjanyan Michael G Preventive cancer vaccine based on brother of regulator of imprinted sites molecule (boris)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281061A (en) * 1979-07-27 1981-07-28 Syva Company Double antibody for enhanced sensitivity in immunoassay
CA2372813A1 (en) * 1992-02-06 1993-08-19 L.L. Houston Biosynthetic binding protein for cancer marker
US20040152877A1 (en) * 2002-03-14 2004-08-05 Hillman Jennifer L. Nucleic acid-associated proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003072799A2 (en) * 2002-02-22 2003-09-04 The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services Brother of the regulator of imprinted sites (boris)
WO2005021029A2 (en) * 2003-08-25 2005-03-10 Agadjanyan Michael G Preventive cancer vaccine based on brother of regulator of imprinted sites molecule (boris)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KLENOVA E M ET AL: "The novel BORIS+CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer", SEMINARS IN CANCER BIOLOGY, SAUNDERS SCIENTIFIC PUBLICATIONS, PHILADELPHIA, PA, US, vol. 12, no. 5, October 2002 (2002-10-01), pages 399 - 414, XP002321011, ISSN: 1044-579X *
LOUKINOV D I ET AL: "BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 99, no. 10, 14 May 2002 (2002-05-14), pages 6806 - 6811, XP002321010, ISSN: 0027-8424 *
ROCKLAND IMMUNOCHEMICALS FOR RESEARCH, 28.02.05, XP002382968, Retrieved from the Internet <URL:www.rockland-inc.com/objects/ catalog/product/extras/12282_600-401-907.pdf -> [retrieved on 20060529] *

Also Published As

Publication number Publication date
DE602005014659D1 (en) 2009-07-09
WO2006034335A2 (en) 2006-03-30
ES2325866T3 (en) 2009-09-22
EP1802972A2 (en) 2007-07-04
US20080095805A1 (en) 2008-04-24
ATE432469T1 (en) 2009-06-15
EP1802972B1 (en) 2009-05-27
US7785814B2 (en) 2010-08-31

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