WO2006044294A3 - Analogues de la proteine humaine c - Google Patents

Analogues de la proteine humaine c Download PDF

Info

Publication number
WO2006044294A3
WO2006044294A3 PCT/US2005/036310 US2005036310W WO2006044294A3 WO 2006044294 A3 WO2006044294 A3 WO 2006044294A3 US 2005036310 W US2005036310 W US 2005036310W WO 2006044294 A3 WO2006044294 A3 WO 2006044294A3
Authority
WO
WIPO (PCT)
Prior art keywords
analogs
human protein
protein
human
wild
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/036310
Other languages
English (en)
Other versions
WO2006044294A2 (fr
Inventor
Barbara Anne Swanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of WO2006044294A2 publication Critical patent/WO2006044294A2/fr
Publication of WO2006044294A3 publication Critical patent/WO2006044294A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne des analogues de la protéine humaine C présentant une activité accrue en comparaison avec la protéine C activée humaine de type sauvage.
PCT/US2005/036310 2004-10-14 2005-10-12 Analogues de la proteine humaine c Ceased WO2006044294A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61879804P 2004-10-14 2004-10-14
US60/618,798 2004-10-14

Publications (2)

Publication Number Publication Date
WO2006044294A2 WO2006044294A2 (fr) 2006-04-27
WO2006044294A3 true WO2006044294A3 (fr) 2006-09-28

Family

ID=35632752

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/036310 Ceased WO2006044294A2 (fr) 2004-10-14 2005-10-12 Analogues de la proteine humaine c

Country Status (1)

Country Link
WO (1) WO2006044294A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITFI20070063A1 (it) * 2007-03-15 2008-09-16 Kedrion Spa Concentrato di proteina c contenente proteina s, sua preparazione ed uso.
MX2010005080A (es) 2007-11-07 2010-07-28 Genentech Inc Metodos y composiciones para determinar la sensibilidad de linfoma de celula b al tratamiento con anticuerpos anti-cd40.

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0443874A2 (fr) * 1990-02-23 1991-08-28 Eli Lilly And Company Vecteurs et composés pour l'expression de mutantes de glycosylation de protéine C humaine
WO2000066754A1 (fr) * 1999-04-30 2000-11-09 Eli Lilly And Company Dérivés de protéine c
WO2001036462A2 (fr) * 1999-11-19 2001-05-25 Eli Lilly And Company Derives de proteine c
WO2002032461A2 (fr) * 2000-10-18 2002-04-25 Maxygen Aps Molecules de proteine c ou de type proteine c activee
WO2003106666A2 (fr) * 2002-06-14 2003-12-24 Maxygen Aps Variants de la proteine c presentant des proprietes modifiees

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0443874A2 (fr) * 1990-02-23 1991-08-28 Eli Lilly And Company Vecteurs et composés pour l'expression de mutantes de glycosylation de protéine C humaine
WO2000066754A1 (fr) * 1999-04-30 2000-11-09 Eli Lilly And Company Dérivés de protéine c
WO2001036462A2 (fr) * 1999-11-19 2001-05-25 Eli Lilly And Company Derives de proteine c
WO2002032461A2 (fr) * 2000-10-18 2002-04-25 Maxygen Aps Molecules de proteine c ou de type proteine c activee
WO2003106666A2 (fr) * 2002-06-14 2003-12-24 Maxygen Aps Variants de la proteine c presentant des proprietes modifiees

Also Published As

Publication number Publication date
WO2006044294A2 (fr) 2006-04-27

Similar Documents

Publication Publication Date Title
EP1898991A4 (fr) Modification d'activite de proteine
ZA200710330B (en) Methods of purifying FC region containing proteins
WO2007082923A3 (fr) Utilisation de microbilles de proteines dans le domaine cosmetique
WO2009002947A3 (fr) Composés et peptides de liaison au récepteur de trail
PL1671529T3 (pl) Kombajn zbożowy
WO2010065815A3 (fr) Mini peptides d'hépcidine et leurs procédés d'utilisation
TW200638934A (en) Heteroaryl compounds as P2Y1 receptor inhibitors
WO2004092215A3 (fr) Methodes therapeutiques utilisant des agents liants specifiques de l'angiopoietine-2 humaine
EA200970403A1 (ru) Бициклические триазолы в качестве модуляторов протеинкиназы
WO2005019258A3 (fr) Compositions et methodes de traitement de maladies relatives au systeme immunitaire
WO2006117217A3 (fr) Nouvelle utilisation de spiegelmers
WO2006015159A3 (fr) Inhibiteurs de canal a potassium
EP2077266A4 (fr) Dérivé de 2-pyridinecarboxamide ayant une activité d'activation de la gk
EP1827571A4 (fr) Modification de l'activite proteique
EP1829968A4 (fr) Proteine mutante presentant une activite de production de peptides
EP1871793A4 (fr) Protooncogène humain et protéine codée par celui-ci
GB0500231D0 (en) Compounds which bind to the active site of protein kinase enzymes
WO2007072201A3 (fr) 3-aminocyclopentanecarboxamides en tant que modulateurs de recepteurs de chimiokine
WO2010000851A3 (fr) Procédés pour moduler l’angiogenèse via la dystrophine dp71
EP1779867A4 (fr) Promoteur de la régénérescence nerveuse
WO2007050348A3 (fr) Inhibiteurs du canal potassique
EP1766073A4 (fr) Amélioration de l'expression des protéines
WO2006076370A3 (fr) Cyclopentanes ou cyclopentanones substitues utilises en tant qu'agents therapeutiques
EP1908786A4 (fr) Préparation de 2-cyanoacrylate
WO2004081199A3 (fr) Nouvelles compositions et methodes de traitement de troubles du systeme immunitaire

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BW BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE EG ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KM KP KR KZ LC LK LR LS LT LU LV LY MA MD MG MK MN MW MX MZ NA NG NI NO NZ OM PG PH PL PT RO RU SC SD SE SG SK SL SM SY TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): BW GH GM KE LS MW MZ NA SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LT LU LV MC NL PL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 05807454

Country of ref document: EP

Kind code of ref document: A2