WO2006084083A3 - Devices for delivering agents to a vaginal tract - Google Patents

Devices for delivering agents to a vaginal tract Download PDF

Info

Publication number
WO2006084083A3
WO2006084083A3 PCT/US2006/003757 US2006003757W WO2006084083A3 WO 2006084083 A3 WO2006084083 A3 WO 2006084083A3 US 2006003757 W US2006003757 W US 2006003757W WO 2006084083 A3 WO2006084083 A3 WO 2006084083A3
Authority
WO
WIPO (PCT)
Prior art keywords
devices
vaginal tract
delivering agents
polymeric material
porous polymeric
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/003757
Other languages
French (fr)
Other versions
WO2006084083A2 (en
Inventor
Lance J Bronnenkant
Anu Mahashabde
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Womens Health Inc
Original Assignee
Duramed Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duramed Pharmaceuticals Inc filed Critical Duramed Pharmaceuticals Inc
Priority to CA002596933A priority Critical patent/CA2596933A1/en
Priority to EP06720187A priority patent/EP1853221A2/en
Publication of WO2006084083A2 publication Critical patent/WO2006084083A2/en
Publication of WO2006084083A3 publication Critical patent/WO2006084083A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is directed to devices for delivering agents to a vaginal tract, a device of the invention comprises a non-porous polymeric material substantially impermeable to an environment of the vaginal tract, the non-porous polymeric material forming a closed envelope which forms an internal space, wherein the closed envelope contains two or more distinct apertures.
PCT/US2006/003757 2005-02-03 2006-02-03 Devices for delivering agents to a vaginal tract Ceased WO2006084083A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002596933A CA2596933A1 (en) 2005-02-03 2006-02-03 Devices for delivering agents to a vaginal tract
EP06720187A EP1853221A2 (en) 2005-02-03 2006-02-03 Devices for delivering agents to a vaginal tract

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64907805P 2005-02-03 2005-02-03
US60/649,078 2005-02-03

Publications (2)

Publication Number Publication Date
WO2006084083A2 WO2006084083A2 (en) 2006-08-10
WO2006084083A3 true WO2006084083A3 (en) 2007-03-15

Family

ID=36777939

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/003757 Ceased WO2006084083A2 (en) 2005-02-03 2006-02-03 Devices for delivering agents to a vaginal tract

Country Status (4)

Country Link
US (1) US20060185678A1 (en)
EP (1) EP1853221A2 (en)
CA (1) CA2596933A1 (en)
WO (1) WO2006084083A2 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2013000002A (en) * 2001-07-27 2013-04-29 Teva Womens Health Inc Differential interferometric scanning near-field confocal microscopy.
EP2437684B1 (en) 2009-06-03 2022-06-15 ForSight Vision5, Inc. Anterior segment drug delivery
US20120053534A1 (en) * 2010-06-22 2012-03-01 Anu Mahashabde Intravaginal devices comprising anticholinergic agents, and methods of making thereof
US8580294B2 (en) 2010-10-19 2013-11-12 International Partnership For Microbicides Platinum-catalyzed intravaginal rings
WO2012065073A2 (en) * 2010-11-12 2012-05-18 The University Of Utah Research Foundation Intravaginal devices for controlled delivery of lubricants
EP2755615B1 (en) 2011-09-14 2022-04-06 Forsight Vision5, Inc. Ocular insert apparatus
DK2911623T3 (en) 2012-10-26 2019-10-28 Forsight Vision5 Inc Ophthalmic system for long-term release of drug into the eye
US10137031B2 (en) 2013-11-14 2018-11-27 International Partnership For Microbicides, Inc. Combination therapy intravaginal rings
US20160296532A1 (en) 2015-04-13 2016-10-13 Forsight Vision5, Inc. Ocular Insert Composition of a Semi-Crystalline or Crystalline Pharmaceutically Active Agent

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996019196A1 (en) * 1994-12-19 1996-06-27 Galen (Chemicals) Limited INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
WO2001013780A2 (en) * 1999-08-26 2001-03-01 Fei Technologies, Inc. Apparatus and method for anesthetizing the cervical region of a female
WO2003018026A1 (en) * 2001-08-31 2003-03-06 Pantarhei Bioscience B.V. Use of estrogenic compounds in combination with progestogenic compounds in hormone-replacement therapy
US20040191308A1 (en) * 2003-03-28 2004-09-30 Linda Mosack Using a laser for cutting a hole in a capsule for controlled drug delivery
WO2005004837A1 (en) * 2003-07-10 2005-01-20 Galen (Chemicals) Limited Intravaginal drug delivery devices

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB972128A (en) * 1960-01-21 1964-10-07 Wellcome Found Pellets for supplying biologically active substances to ruminants and the manufacture of such pellets
US3521637A (en) * 1967-11-28 1970-07-28 Nelson J Waterbury Tampon or similar sanitary napkin containing vitamin a
US3630200A (en) * 1969-06-09 1971-12-28 Alza Corp Ocular insert
US3924622A (en) * 1973-10-11 1975-12-09 Mead Johnson & Co Zero-order release method
US3851648A (en) * 1973-10-11 1974-12-03 Mead Johnson & Co Zero-order release device
US4136162A (en) * 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
US4286587A (en) * 1978-10-11 1981-09-01 Alza Corporation Vaginal drug delivery system made from polymer
US4327725A (en) * 1980-11-25 1982-05-04 Alza Corporation Osmotic device with hydrogel driving member
US4557925A (en) * 1982-07-08 1985-12-10 Ab Ferrosan Membrane-coated sustained-release tablets and method
US5366738A (en) * 1982-07-29 1994-11-22 Merck & Co., Inc. Controlled release drug dispersion delivery device
GB8319766D0 (en) * 1983-07-22 1983-08-24 Graham N B Controlled release device
GB8403138D0 (en) * 1984-02-07 1984-03-14 Graham N B Sustained release of active ingredient
US4601893A (en) * 1984-02-08 1986-07-22 Pfizer Inc. Laminate device for controlled and prolonged release of substances to an ambient environment and method of use
US4596576A (en) * 1984-10-12 1986-06-24 Akzo N.V. Release system for two or more active substances
US4931279A (en) * 1985-08-16 1990-06-05 Bausch & Lomb Incorporated Sustained release formulation containing an ion-exchange resin
US4830860A (en) * 1986-10-30 1989-05-16 Pfizer Inc. Stressed polymeric device for controlled release of a substance to an ambient environment
US4792448A (en) * 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
GB8717168D0 (en) * 1987-07-21 1987-08-26 Roussel Lab Ltd Controlled-release device
GB8820353D0 (en) * 1988-08-26 1988-09-28 Staniforth J N Controlled release tablet
CA2178620A1 (en) * 1993-12-08 1995-06-15 Lisa B. Jungherr Microsphere drug delivery system
FR2745180B1 (en) * 1996-02-23 1998-05-07 Dow Corning Sa METHOD FOR MANUFACTURING CONTROLLED RELEASE DEVICES
US5972372A (en) * 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
ATE203157T1 (en) * 1996-12-20 2001-08-15 Alza Corp INJECTABLE DEPOSIT GEL PREPARATION AND PRODUCTION METHOD
US6039968A (en) * 1997-06-24 2000-03-21 Hoechst Marion Roussel Intravaginal drug delivery device
US6264972B1 (en) * 1999-11-10 2001-07-24 Tolland Development Company, Llc Tampon
US6569152B2 (en) * 2000-03-21 2003-05-27 Farrington Pharmaceuticals, Llc Sustained release delivery systems for solutes

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996019196A1 (en) * 1994-12-19 1996-06-27 Galen (Chemicals) Limited INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
WO2001013780A2 (en) * 1999-08-26 2001-03-01 Fei Technologies, Inc. Apparatus and method for anesthetizing the cervical region of a female
WO2003018026A1 (en) * 2001-08-31 2003-03-06 Pantarhei Bioscience B.V. Use of estrogenic compounds in combination with progestogenic compounds in hormone-replacement therapy
US20040191308A1 (en) * 2003-03-28 2004-09-30 Linda Mosack Using a laser for cutting a hole in a capsule for controlled drug delivery
WO2005004837A1 (en) * 2003-07-10 2005-01-20 Galen (Chemicals) Limited Intravaginal drug delivery devices

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BUCKLER HELEN ET AL: "The effect of a novel vaginal ring delivering oestradiol acetate on climacteric symptoms in postmenopausal women.", BJOG : AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY. AUG 2003, vol. 110, no. 8, August 2003 (2003-08-01), pages 753 - 759, XP002405626, ISSN: 1470-0328 *
KANCHARLA V V ET AL: "FABRICATION OF BIODEGRADABLE POLYMERIC MICRO-DEVICES USING LASER MICROMACHINING", BIOMEDICAL MICRODEVICES, KLUWER, DORDRECHT,, NL, vol. 4, no. 2, May 2002 (2002-05-01), pages 105 - 109, XP008017522, ISSN: 1387-2176 *

Also Published As

Publication number Publication date
CA2596933A1 (en) 2006-08-10
EP1853221A2 (en) 2007-11-14
US20060185678A1 (en) 2006-08-24
WO2006084083A2 (en) 2006-08-10

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