WO2006085984A3 - Immune cell biosensors and methods of using same - Google Patents

Immune cell biosensors and methods of using same Download PDF

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Publication number
WO2006085984A3
WO2006085984A3 PCT/US2005/024491 US2005024491W WO2006085984A3 WO 2006085984 A3 WO2006085984 A3 WO 2006085984A3 US 2005024491 W US2005024491 W US 2005024491W WO 2006085984 A3 WO2006085984 A3 WO 2006085984A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
same
immune cell
cell biosensors
detecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/024491
Other languages
French (fr)
Other versions
WO2006085984A2 (en
WO2006085984A9 (en
Inventor
Milton G Smith
Krith D Crawford
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amaox Inc
Original Assignee
Amaox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amaox Inc filed Critical Amaox Inc
Priority to AU2005327199A priority Critical patent/AU2005327199A1/en
Priority to JP2007520583A priority patent/JP2008505649A/en
Priority to US11/631,574 priority patent/US20080261258A1/en
Priority to EP05856874A priority patent/EP1787128A2/en
Priority to CA002614507A priority patent/CA2614507A1/en
Publication of WO2006085984A2 publication Critical patent/WO2006085984A2/en
Publication of WO2006085984A9 publication Critical patent/WO2006085984A9/en
Anticipated expiration legal-status Critical
Publication of WO2006085984A3 publication Critical patent/WO2006085984A3/en
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6842—Proteomic analysis of subsets of protein mixtures with reduced complexity, e.g. membrane proteins, phosphoproteins, organelle proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845—Methods of identifying protein-protein interactions in protein mixtures
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

The present invention relates to immunological cells that are useful in detecting changes in physiological states, which provide for methods of diagnosing diseases or monitoring the course of patient therapy. Also provided are arrays of antigen presenting cell-specific markers for detecting changes in physiological states, and methods of detecting such changes.
PCT/US2005/024491 2004-07-09 2005-07-11 Immune cell biosensors and methods of using same Ceased WO2006085984A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2005327199A AU2005327199A1 (en) 2004-07-09 2005-07-11 Immune cell biosensors and methods of using same
JP2007520583A JP2008505649A (en) 2004-07-09 2005-07-11 Immune cell biosensor and method of use thereof
US11/631,574 US20080261258A1 (en) 2004-07-09 2005-07-11 Immune Cell Biosensors and Methods of Using Same
EP05856874A EP1787128A2 (en) 2004-07-09 2005-07-11 Immune cell biosensors and methods of using same
CA002614507A CA2614507A1 (en) 2004-07-09 2005-07-11 Immune cell biosensors and methods of using same

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US58654604P 2004-07-09 2004-07-09
US60/586,546 2004-07-09
US61245404P 2004-09-23 2004-09-23
US60/612,454 2004-09-23
US61373304P 2004-09-28 2004-09-28
US60/613,733 2004-09-28
US61492404P 2004-09-29 2004-09-29
US60/614,924 2004-09-29

Publications (3)

Publication Number Publication Date
WO2006085984A2 WO2006085984A2 (en) 2006-08-17
WO2006085984A9 WO2006085984A9 (en) 2006-10-26
WO2006085984A3 true WO2006085984A3 (en) 2007-02-22

Family

ID=36608553

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/024491 Ceased WO2006085984A2 (en) 2004-07-09 2005-07-11 Immune cell biosensors and methods of using same

Country Status (6)

Country Link
US (1) US20080261258A1 (en)
EP (1) EP1787128A2 (en)
JP (1) JP2008505649A (en)
AU (1) AU2005327199A1 (en)
CA (1) CA2614507A1 (en)
WO (1) WO2006085984A2 (en)

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US8812249B2 (en) 2009-06-25 2014-08-19 University Hospital Of North Staffordshire Nhs Trust Analyzer apparatus and methods for lung disease

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US20040219565A1 (en) 2002-10-21 2004-11-04 Sakari Kauppinen Oligonucleotides useful for detecting and analyzing nucleic acids of interest
KR20080006617A (en) 2005-04-15 2008-01-16 백톤 디킨슨 앤드 컴퍼니 Diagnosis of Sepsis
CN101432626B (en) 2006-04-04 2013-06-19 神谷来克斯公司 Highly sensitive systems and methods for troponin analysis
US7838250B1 (en) 2006-04-04 2010-11-23 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
CN102046070A (en) 2008-03-28 2011-05-04 俄亥俄州立大学 Rapid diagnosis of a disease condition using infrared spectroscopy
US8614419B2 (en) * 2008-03-28 2013-12-24 The Ohio State University Rapid diagnosis of a disease condition using infrared spectroscopy
US8669113B2 (en) 2008-04-03 2014-03-11 Becton, Dickinson And Company Advanced detection of sepsis
AU2010259022B2 (en) 2009-06-08 2016-05-12 Singulex, Inc. Highly sensitive biomarker panels
AU2011205230A1 (en) 2010-01-13 2012-08-02 Caris Life Sciences Switzerland Holdings Gmbh Detection of gastrointestinal disorders
US9128101B2 (en) 2010-03-01 2015-09-08 Caris Life Sciences Switzerland Holdings Gmbh Biomarkers for theranostics
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
US10420665B2 (en) 2010-06-13 2019-09-24 W. L. Gore & Associates, Inc. Intragastric device for treating obesity
US10010439B2 (en) 2010-06-13 2018-07-03 Synerz Medical, Inc. Intragastric device for treating obesity
US9526648B2 (en) 2010-06-13 2016-12-27 Synerz Medical, Inc. Intragastric device for treating obesity
US8628554B2 (en) 2010-06-13 2014-01-14 Virender K. Sharma Intragastric device for treating obesity
US20140051183A1 (en) * 2010-06-18 2014-02-20 B.R.A.H.M.S Gmbh Biomarkers for the prediction of incident cancer
US9244074B2 (en) 2011-06-07 2016-01-26 University Of Hawaii Biomarker of asbestos exposure and mesothelioma
WO2012170742A2 (en) 2011-06-07 2012-12-13 University Of Hawaii Treatment and prevention of cancer with hmgb1 antagonists
CA2863819C (en) 2012-02-09 2021-11-23 Memed Diagnostics Ltd. Signatures and determinants for diagnosing infections and methods of use thereof
WO2014164365A1 (en) * 2013-03-09 2014-10-09 Harry Stylli Methods of detecting head and neck cancer
EP4202441A3 (en) 2013-03-09 2023-07-26 Immunis.AI, Inc. Gene expression profile in macrophages for the diagnosis of cancer
WO2014164362A1 (en) * 2013-03-09 2014-10-09 Harry Stylli Methods of detecting prostate cancer
WO2015156876A2 (en) * 2014-01-17 2015-10-15 Massachusetts Institute Of Technology Integrated electrical profiling system for measuring leukocytes activation from whole blood
US10303846B2 (en) 2014-08-14 2019-05-28 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
US10626464B2 (en) 2014-09-11 2020-04-21 Cell Mdx, Llc Methods of detecting prostate cancer
BR112017011557A2 (en) * 2014-12-05 2018-03-06 Lifecycle Tech Pty Ltd system for determining immune status or immune cycle, methods for determining immune status and / or immune cycle, for optimizing a physiological response, for improving a physiological response, and for determining an immune state or immune cycle.
US20170269081A1 (en) 2014-12-11 2017-09-21 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
CN108699609A (en) 2016-03-03 2018-10-23 米密德诊断学有限公司 Analysis of RNA for diagnosis of infection type
US10779980B2 (en) 2016-04-27 2020-09-22 Synerz Medical, Inc. Intragastric device for treating obesity
CA3027341A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
US11340223B2 (en) 2016-07-10 2022-05-24 Memed Diagnostics Ltd. Early diagnosis of infections
EP3519833B1 (en) 2016-09-29 2024-08-14 MeMed Diagnostics Ltd. Methods of prognosis and treatment
JP6844912B2 (en) * 2017-02-28 2021-03-17 株式会社ハウス食品分析テクノサービス Method for determining when foreign matter is mixed by imaging mass spectrometry
CN107545135B (en) * 2017-08-15 2019-03-05 璞晞（广州）生物免疫技术有限公司 The construction method of hepatitis B liver diseases T lymphocyte immune state application assessment models
CN107328937A (en) * 2017-08-24 2017-11-07 璞晞（广州）生物免疫技术有限公司 For the construction method for the practicality model for evaluating hepatitis B hepatopathy NK cell functions
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EP3971572A1 (en) * 2017-09-13 2022-03-23 B.R.A.H.M.S GmbH Proadrenomedullin as a marker for abnormal platelet levels
WO2020037609A1 (en) * 2018-08-23 2020-02-27 西门子股份公司 Method, device and system for forming fusion model, medium, processor and terminal
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KR20260043144A (en) 2019-12-02 2026-03-31 캐리스 엠피아이, 아이엔씨. Pan-cancer platinum response predictor
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Publication number Priority date Publication date Assignee Title
US8812249B2 (en) 2009-06-25 2014-08-19 University Hospital Of North Staffordshire Nhs Trust Analyzer apparatus and methods for lung disease

Also Published As

Publication number Publication date
US20080261258A1 (en) 2008-10-23
WO2006085984A2 (en) 2006-08-17
CA2614507A1 (en) 2006-08-17
JP2008505649A (en) 2008-02-28
WO2006085984A9 (en) 2006-10-26
AU2005327199A1 (en) 2006-08-17
EP1787128A2 (en) 2007-05-23

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