WO2006089973A3 - Dosage form containing oxycodone and naloxone - Google Patents

Dosage form containing oxycodone and naloxone Download PDF

Info

Publication number
WO2006089973A3
WO2006089973A3 PCT/EP2006/060341 EP2006060341W WO2006089973A3 WO 2006089973 A3 WO2006089973 A3 WO 2006089973A3 EP 2006060341 W EP2006060341 W EP 2006060341W WO 2006089973 A3 WO2006089973 A3 WO 2006089973A3
Authority
WO
WIPO (PCT)
Prior art keywords
naloxone
dosage form
form containing
containing oxycodone
oxycodone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2006/060341
Other languages
French (fr)
Other versions
WO2006089973A2 (en
Inventor
Petra Leyendecker
Michael Hopp
Kevin Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euro Celtique SA
Original Assignee
Euro Celtique SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34933990&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2006089973(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to HK08102490.3A priority Critical patent/HK1111604B/en
Priority to CA2599156A priority patent/CA2599156C/en
Priority to SI200631121T priority patent/SI1855657T1/en
Priority to JP2007557493A priority patent/JP2008531650A/en
Priority to AU2006217870A priority patent/AU2006217870B2/en
Priority to MX2007010494A priority patent/MX2007010494A/en
Priority to BRPI0607975-0A priority patent/BRPI0607975A2/en
Priority to AT06708567T priority patent/ATE517611T1/en
Priority to EP15180143.8A priority patent/EP2962686B1/en
Priority to PL06708567T priority patent/PL1855657T3/en
Priority to EP06708567A priority patent/EP1855657B1/en
Priority to US11/885,288 priority patent/US20080145429A1/en
Priority to DE202006020095U priority patent/DE202006020095U1/en
Application filed by Euro Celtique SA filed Critical Euro Celtique SA
Priority to MEP-2011-173A priority patent/ME01262B/en
Priority to DK06708567.0T priority patent/DK1855657T3/en
Priority to EP19167974.5A priority patent/EP3578173B1/en
Priority to HR20110775T priority patent/HRP20110775T1/en
Publication of WO2006089973A2 publication Critical patent/WO2006089973A2/en
Publication of WO2006089973A3 publication Critical patent/WO2006089973A3/en
Priority to FI20070153U priority patent/FI7750U1/en
Priority to IL185514A priority patent/IL185514A0/en
Anticipated expiration legal-status Critical
Priority to IL196539A priority patent/IL196539A0/en
Priority to AU2009201019A priority patent/AU2009201019B2/en
Priority to US12/945,164 priority patent/US20110172259A1/en
Priority to US13/329,218 priority patent/US20120225901A1/en
Priority to US14/044,175 priority patent/US20140031382A1/en
Priority to US15/467,877 priority patent/US20180008593A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention concerns a dosage form comprising oxycodone and naloxone which is characterized by specific in vivo parameters such as tmax, Cmax,AUCt value, mean bowel function score and/or duration of analgesic efficacy.
PCT/EP2006/060341 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone Ceased WO2006089973A2 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
DK06708567.0T DK1855657T3 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
MEP-2011-173A ME01262B (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
SI200631121T SI1855657T1 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
JP2007557493A JP2008531650A (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
AU2006217870A AU2006217870B2 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
MX2007010494A MX2007010494A (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone.
BRPI0607975-0A BRPI0607975A2 (en) 2005-02-28 2006-02-28 dosage form containing oxycodone and naloxone
AT06708567T ATE517611T1 (en) 2005-02-28 2006-02-28 PHARMACEUTICAL FORM CONTAINING OXYCODONE AND NALOXONE
EP15180143.8A EP2962686B1 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
PL06708567T PL1855657T3 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
EP06708567A EP1855657B1 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
US11/885,288 US20080145429A1 (en) 2005-02-28 2006-02-28 Dosage Form Containing Oxycodone and Naloxone
DE202006020095U DE202006020095U1 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
HK08102490.3A HK1111604B (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
EP19167974.5A EP3578173B1 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
HR20110775T HRP20110775T1 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
CA2599156A CA2599156C (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone
FI20070153U FI7750U1 (en) 2005-02-28 2007-04-13 A dosage form containing oxycodone and naloxone
IL185514A IL185514A0 (en) 2005-02-28 2007-08-26 Dosage form containing oxycodone and naloxone
IL196539A IL196539A0 (en) 2005-02-28 2009-01-15 Dosage form containing oxycodone and naloxone
AU2009201019A AU2009201019B2 (en) 2005-02-28 2009-03-13 Dosage form containing oxycodone and naloxone
US12/945,164 US20110172259A1 (en) 2005-02-28 2010-11-12 Dosage form containing oxycodone and naloxone
US13/329,218 US20120225901A1 (en) 2005-02-28 2011-12-16 Dosage form containing oxycodone and naloxone
US14/044,175 US20140031382A1 (en) 2005-02-28 2013-10-02 Dosage form containing oxycodone and naloxone
US15/467,877 US20180008593A1 (en) 2005-02-28 2017-03-23 Dosage form containing oxycodone and naloxone

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05004377A EP1695700A1 (en) 2005-02-28 2005-02-28 Dosage form containing oxycodone and naloxone
EP05004377.7 2005-02-28

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/885,288 A-371-Of-International US20080145429A1 (en) 2005-02-28 2006-02-28 Dosage Form Containing Oxycodone and Naloxone
US12/945,164 Continuation US20110172259A1 (en) 2005-02-28 2010-11-12 Dosage form containing oxycodone and naloxone

Publications (2)

Publication Number Publication Date
WO2006089973A2 WO2006089973A2 (en) 2006-08-31
WO2006089973A3 true WO2006089973A3 (en) 2006-12-28

Family

ID=34933990

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/060341 Ceased WO2006089973A2 (en) 2005-02-28 2006-02-28 Dosage form containing oxycodone and naloxone

Country Status (26)

Country Link
US (5) US20080145429A1 (en)
EP (5) EP1695700A1 (en)
JP (2) JP2008531650A (en)
KR (1) KR20070107805A (en)
CN (2) CN101128191A (en)
AT (1) ATE517611T1 (en)
AU (2) AU2006217870B2 (en)
BR (1) BRPI0607975A2 (en)
CA (3) CA2599156C (en)
CY (1) CY1111967T1 (en)
DE (2) DE202006020095U1 (en)
DK (2) DK1855657T3 (en)
ES (1) ES2370409T3 (en)
FI (1) FI7750U1 (en)
HR (1) HRP20110775T1 (en)
IL (2) IL185514A0 (en)
ME (1) ME01262B (en)
MX (1) MX2007010494A (en)
NZ (1) NZ588875A (en)
PL (1) PL1855657T3 (en)
PT (1) PT1855657E (en)
RS (1) RS51984B (en)
RU (1) RU2428985C2 (en)
SI (1) SI1855657T1 (en)
UA (1) UA93543C2 (en)
WO (1) WO2006089973A2 (en)

Cited By (6)

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US8846090B2 (en) 2002-04-05 2014-09-30 Euro-Celtique S.A. Matrix for sustained, invariant and independent release of active compounds
US8936808B1 (en) 1997-12-22 2015-01-20 Purdue Pharma L.P. Opioid agonist/opioid antagonist/acetaminophen combinations
US8969369B2 (en) 2001-05-11 2015-03-03 Purdue Pharma L.P. Abuse-resistant controlled-release opioid dosage form
US9205082B2 (en) 1997-12-22 2015-12-08 Purdue Pharma L.P. Opioid agonist/antagonist combinations
US9271940B2 (en) 2009-03-10 2016-03-01 Purdue Pharma L.P. Immediate release pharmaceutical compositions comprising oxycodone and naloxone
US11135216B2 (en) 2009-08-07 2021-10-05 Indivior Uk Limited Sublingual and buccal film compositions

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US7056500B2 (en) 2001-10-18 2006-06-06 Nektar Therapeutics Al, Corporation Polymer conjugates of opioid antagonists
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
DE10361596A1 (en) 2003-12-24 2005-09-29 Grünenthal GmbH Process for producing an anti-abuse dosage form
DE10336400A1 (en) 2003-08-06 2005-03-24 Grünenthal GmbH Anti-abuse dosage form
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE102005005446A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Break-resistant dosage forms with sustained release
EP1604666A1 (en) 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the Chronic Obstructive Pulmonary Disease (COPD)
EP1604667A1 (en) * 2004-06-08 2005-12-14 Euro-Celtique S.A. Opioids for the treatment of the restless leg syndrome
DE102004032049A1 (en) 2004-07-01 2006-01-19 Grünenthal GmbH Anti-abuse, oral dosage form
KR100905511B1 (en) * 2005-01-28 2009-07-01 유로-셀띠끄 소시에떼 아노님 Alcohol Resistant Formulations
DE102005005449A1 (en) 2005-02-04 2006-08-10 Grünenthal GmbH Process for producing an anti-abuse dosage form
EP1695700A1 (en) 2005-02-28 2006-08-30 Euro-Celtique S.A. Dosage form containing oxycodone and naloxone
EP1702558A1 (en) 2005-02-28 2006-09-20 Euro-Celtique S.A. Method and device for the assessment of bowel function
DE202006018609U1 (en) * 2006-08-29 2007-05-16 Euro-Celtique S.A. Needle-free apparatus for administrating pharmaceutical composition in humans, comprises a housing; auxiliary substance to force a pharmaceutical composition from a package into human body; a composition comprising analgesic, e.g. opioids
JP2010509227A (en) * 2006-11-07 2010-03-25 ネクター セラピューティックス エイエル，コーポレイション Opioid agonist and opioid antagonist dosage forms and co-administration
US20090004231A1 (en) 2007-06-30 2009-01-01 Popp Shane M Pharmaceutical dosage forms fabricated with nanomaterials for quality monitoring
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US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
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AU2014273227B2 (en) 2013-05-29 2019-08-15 Grunenthal Gmbh Tamper-resistant dosage form containing one or more particles
AU2014289187B2 (en) 2013-07-12 2019-07-11 Grunenthal Gmbh Tamper-resistant dosage form containing ethylene-vinyl acetate polymer
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