WO2006099604A3 - Methods and compositions for assay readouts on multiple analytical platforms - Google Patents

Methods and compositions for assay readouts on multiple analytical platforms Download PDF

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Publication number
WO2006099604A3
WO2006099604A3 PCT/US2006/009898 US2006009898W WO2006099604A3 WO 2006099604 A3 WO2006099604 A3 WO 2006099604A3 US 2006009898 W US2006009898 W US 2006009898W WO 2006099604 A3 WO2006099604 A3 WO 2006099604A3
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WIPO (PCT)
Prior art keywords
compositions
tags
methods
labeling
oligonucleotide tags
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/US2006/009898
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French (fr)
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WO2006099604A2 (en
Inventor
Sydney Brenner
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Compass Genetics LLC
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Compass Genetics LLC
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Application filed by Compass Genetics LLC filed Critical Compass Genetics LLC
Priority to EP06738889A priority Critical patent/EP1856293A2/en
Publication of WO2006099604A2 publication Critical patent/WO2006099604A2/en
Anticipated expiration legal-status Critical
Publication of WO2006099604A3 publication Critical patent/WO2006099604A3/en
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides methods and compositions for reading out the results of multiplex assays on various analytical platforms, such as microarrays, bead arrays, electrophoresis devices, and the like. An important feature of the invention includes methods for converting different sets of oligonucleotide tags used for labeling into oligonucleotide tags specific for a particular analytical platform. The invention further includes compositions comprising oligonucleotide tags having convenient properties for labeling and conversion, particularly ligation tags that employ ligation reaction specificity as well as sequence specificity in order to discriminate between tags.
PCT/US2006/009898 2005-03-16 2006-03-16 Methods and compositions for assay readouts on multiple analytical platforms Ceased WO2006099604A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06738889A EP1856293A2 (en) 2005-03-16 2006-03-16 Methods and compositions for assay readouts on multiple analytical platforms

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US66216705P 2005-03-16 2005-03-16
US60/662,167 2005-03-16
US73885205P 2005-11-21 2005-11-21
US60/738,852 2005-11-21
US74048005P 2005-11-29 2005-11-29
US60/740,480 2005-11-29
US77509806P 2006-02-21 2006-02-21
US60/775,098 2006-02-21

Publications (2)

Publication Number Publication Date
WO2006099604A2 WO2006099604A2 (en) 2006-09-21
WO2006099604A3 true WO2006099604A3 (en) 2009-04-23

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PCT/US2006/009898 Ceased WO2006099604A2 (en) 2005-03-16 2006-03-16 Methods and compositions for assay readouts on multiple analytical platforms

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US (1) US20060211030A1 (en)
EP (1) EP1856293A2 (en)
WO (1) WO2006099604A2 (en)

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US20060211030A1 (en) 2006-09-21
WO2006099604A2 (en) 2006-09-21

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