WO2006116361A3 - Methods and devices for monitoring platelet function - Google Patents

Methods and devices for monitoring platelet function Download PDF

Info

Publication number
WO2006116361A3
WO2006116361A3 PCT/US2006/015565 US2006015565W WO2006116361A3 WO 2006116361 A3 WO2006116361 A3 WO 2006116361A3 US 2006015565 W US2006015565 W US 2006015565W WO 2006116361 A3 WO2006116361 A3 WO 2006116361A3
Authority
WO
WIPO (PCT)
Prior art keywords
monitoring
methods
devices
passageway
platelet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/015565
Other languages
French (fr)
Other versions
WO2006116361A2 (en
Inventor
William Haworth
Vincent Swenson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PlaCor Inc
Original Assignee
PlaCor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PlaCor Inc filed Critical PlaCor Inc
Priority to EP06751327A priority Critical patent/EP1875232A2/en
Priority to JP2008509024A priority patent/JP2008539438A/en
Publication of WO2006116361A2 publication Critical patent/WO2006116361A2/en
Publication of WO2006116361A3 publication Critical patent/WO2006116361A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Ecology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

A method of monitoring platelet function comprising: passing blood removed from a mammal through a passageway comprising a spring to contact the spring to generate a platelet mass in the passageway; and monitoring the flow or composition of the blood in the passageway to detect formation of the platelet mass. Alternatively, the method comprises passing blood removed from a mammal through two or more passageways comprising an obstruction or irregularity, to contact the obstruction or the wall of the passageway at the irregularity, to generate a platelet mass in the two or more passageways; and monitoring the flow or composition of the blood in the passageways to detect formation of the platelet masses. Devices and articles for performing the methods are also described.
PCT/US2006/015565 2005-04-25 2006-04-24 Methods and devices for monitoring platelet function Ceased WO2006116361A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP06751327A EP1875232A2 (en) 2005-04-25 2006-04-24 Methods and devices for monitoring platelet function
JP2008509024A JP2008539438A (en) 2005-04-25 2006-04-24 Method and device for monitoring platelet function

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67450105P 2005-04-25 2005-04-25
US60/674,501 2005-04-25

Publications (2)

Publication Number Publication Date
WO2006116361A2 WO2006116361A2 (en) 2006-11-02
WO2006116361A3 true WO2006116361A3 (en) 2007-04-19

Family

ID=37011931

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/015565 Ceased WO2006116361A2 (en) 2005-04-25 2006-04-24 Methods and devices for monitoring platelet function

Country Status (4)

Country Link
US (1) US20060269978A1 (en)
EP (1) EP1875232A2 (en)
JP (1) JP2008539438A (en)
WO (1) WO2006116361A2 (en)

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US7393690B2 (en) * 2003-05-06 2008-07-01 Thrombodyne, Inc. Systems and methods for measuring fluid properties
JP2008185564A (en) * 2007-01-31 2008-08-14 Fujimori Kogyo Co Ltd Blood coagulation test method and blood coagulation test device
US8289514B2 (en) * 2008-03-05 2012-10-16 Aggredyne, Inc. Systems for measuring properties of a physiological fluid suspension
WO2010039988A1 (en) * 2008-10-01 2010-04-08 The Johns Hopkins University Thromboxane generation analysis for cardiovascular events
KR101193566B1 (en) * 2011-08-10 2012-10-22 고려대학교 산학협력단 Apparatus of platelet multi-function analysis based on micro-chip
KR101363812B1 (en) * 2011-12-27 2014-02-20 고려대학교 산학협력단 Bleeding time measurement apparatus and method by using blood migration ratio
KR101481240B1 (en) * 2012-12-27 2015-01-19 고려대학교 산학협력단 Apparatus and method for monitoring platelet function and drug response in a microfluidic-chip
US9138746B2 (en) * 2013-05-01 2015-09-22 Honeywell International Inc. Fluid stop for measured sample containment
US12607641B2 (en) * 2014-11-14 2026-04-21 Haemonetics Corporation Apparatus and method to determine stroke subtype
WO2017044055A1 (en) * 2015-09-08 2017-03-16 Elbuken Caglar Blood coagulation time measurement method and apparatus

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WO2003023390A2 (en) * 2001-09-07 2003-03-20 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Device for monitoring coagulation status
WO2004024026A2 (en) * 2002-09-10 2004-03-25 Ericson Daniel G Method and device for monitoring platelet function

Also Published As

Publication number Publication date
US20060269978A1 (en) 2006-11-30
EP1875232A2 (en) 2008-01-09
WO2006116361A2 (en) 2006-11-02
JP2008539438A (en) 2008-11-13

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