WO2006119116A3 - Use of platinum group metals in vascular devices and method of texturing platinum group metals - Google Patents

Use of platinum group metals in vascular devices and method of texturing platinum group metals Download PDF

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Publication number
WO2006119116A3
WO2006119116A3 PCT/US2006/016462 US2006016462W WO2006119116A3 WO 2006119116 A3 WO2006119116 A3 WO 2006119116A3 US 2006016462 W US2006016462 W US 2006016462W WO 2006119116 A3 WO2006119116 A3 WO 2006119116A3
Authority
WO
WIPO (PCT)
Prior art keywords
platinum group
group metals
texturing
vascular devices
polycrystalline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/016462
Other languages
French (fr)
Other versions
WO2006119116A2 (en
Inventor
Mike Krivoruchko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Vascular Inc
Original Assignee
Medtronic Vascular Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Vascular Inc filed Critical Medtronic Vascular Inc
Priority to DE602006014135T priority Critical patent/DE602006014135D1/en
Priority to EP06758788A priority patent/EP1885902B1/en
Priority to AT06758788T priority patent/ATE466967T1/en
Priority to JP2008509213A priority patent/JP2008539812A/en
Publication of WO2006119116A2 publication Critical patent/WO2006119116A2/en
Publication of WO2006119116A3 publication Critical patent/WO2006119116A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541—Adjacent bands are arranged out of phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheets or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91583—Adjacent bands being connected to each other by a bridge, whereby at least one of its ends is connected along the length of a strut between two consecutive apices within a band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00035—Other metals or alloys
    • A61F2310/00149—Platinum or Pt-based alloys

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)

Abstract

A method of texturing polycrystalline iridium includes the steps of cold/warm working of the polycrystalline iridium at equal to or below its re-crystallization temperature to break up the polycrystalline structure such that the orientation favors one direction (i.e. the <110> direction), and re-crystallizing the iridium such that a majority of grains are aligned in the preferred direction. The textured polycrystalline material is then used in vascular devices such as stents.
PCT/US2006/016462 2005-04-29 2006-04-28 Use of platinum group metals in vascular devices and method of texturing platinum group metals Ceased WO2006119116A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
DE602006014135T DE602006014135D1 (en) 2005-04-29 2006-04-28 Recrystallized textured iridium stent
EP06758788A EP1885902B1 (en) 2005-04-29 2006-04-28 Stent in recrystallised and textured iridium
AT06758788T ATE466967T1 (en) 2005-04-29 2006-04-28 STENT MADE OF RECRISTALLIZED, TEXTURED IRIDIUM
JP2008509213A JP2008539812A (en) 2005-04-29 2006-04-28 Use of platinum group metals in vascular devices and methods of tailoring platinum group metals into fabrics

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/118,080 US7309353B2 (en) 2005-04-29 2005-04-29 Use of platinum group metals in vascular devices and method of texturing platinum group metals
US11/118,080 2005-04-29

Publications (2)

Publication Number Publication Date
WO2006119116A2 WO2006119116A2 (en) 2006-11-09
WO2006119116A3 true WO2006119116A3 (en) 2006-12-21

Family

ID=36917198

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/016462 Ceased WO2006119116A2 (en) 2005-04-29 2006-04-28 Use of platinum group metals in vascular devices and method of texturing platinum group metals

Country Status (6)

Country Link
US (1) US7309353B2 (en)
EP (1) EP1885902B1 (en)
JP (1) JP2008539812A (en)
AT (1) ATE466967T1 (en)
DE (1) DE602006014135D1 (en)
WO (1) WO2006119116A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070112421A1 (en) * 2005-11-14 2007-05-17 O'brien Barry Medical device with a grooved surface
JP2010509988A (en) * 2006-11-16 2010-04-02 ボストン サイエンティフィック リミテッド Stents that release therapeutic agents to the outer and luminal sides at different times
US20080177376A1 (en) 2007-01-18 2008-07-24 Medtronic Vascular, Inc. Stent With Improved Flexibility and Method for Making Same
US20090076591A1 (en) * 2007-09-19 2009-03-19 Boston Scientific Scimed, Inc. Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface
US7737414B2 (en) * 2007-10-26 2010-06-15 Academia Sinica Atomically sharp iridium tip
US7833266B2 (en) 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
US8128677B2 (en) 2007-12-12 2012-03-06 Intact Vascular LLC Device and method for tacking plaque to a blood vessel wall
US7951193B2 (en) 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
KR101243978B1 (en) 2010-12-23 2013-03-14 전남대학교병원 Coronary artery stent
US9433520B2 (en) 2015-01-29 2016-09-06 Intact Vascular, Inc. Delivery device and method of delivery
US9375336B1 (en) 2015-01-29 2016-06-28 Intact Vascular, Inc. Delivery device and method of delivery
US10993824B2 (en) 2016-01-01 2021-05-04 Intact Vascular, Inc. Delivery device and method of delivery
EP3578142B1 (en) * 2017-02-01 2022-03-23 Kake Educational Institution Okayama University Of Science Bioabsorbable stent
US11660218B2 (en) 2017-07-26 2023-05-30 Intact Vascular, Inc. Delivery device and method of delivery
CN109512558A (en) * 2018-12-31 2019-03-26 杭州天启钛智能科技有限公司 A kind of application method of intravascular stent and intravascular stent
CN115177411B (en) * 2022-07-22 2024-07-12 启晨(上海)医疗器械有限公司 Bronchial valve

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB720025A (en) * 1950-12-22 1954-12-08 Georg Stetter Improvements in or relating to catalysts
GB1134492A (en) * 1964-03-11 1968-11-27 Johnson Matthey Co Ltd Methods of improving the mechanical properties of metals and their alloys
JPH01119595A (en) * 1987-11-02 1989-05-11 Tanaka Kikinzoku Kogyo Kk Material for single crystal growing crucible
US5800511A (en) * 1993-01-19 1998-09-01 Schneider (Usa) Inc Clad composite stent
US6152869A (en) * 1997-12-24 2000-11-28 Korea Atomic Research Energy Research Institute Radioactive stent and process for preparation thereof
US6340368B1 (en) * 1998-10-23 2002-01-22 Medtronic Inc. Implantable device with radiopaque ends
US20040025986A1 (en) * 2002-08-08 2004-02-12 Perry Andrew C. Controlled-grain-precious metal sputter targets
WO2005044361A1 (en) * 2003-11-07 2005-05-19 Merlin Md Pte Ltd Implantable medical devices with enhanced visibility, mechanical properties and biocompatibility
JP2005287568A (en) * 2004-03-31 2005-10-20 Homuzu Giken:Kk Stent

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6399886B1 (en) * 1997-05-02 2002-06-04 General Science & Technology Corp. Multifilament drawn radiopaque high elastic cables and methods of making the same
US6010445A (en) * 1997-09-11 2000-01-04 Implant Sciences Corporation Radioactive medical device and process
US20040110738A1 (en) * 2002-10-22 2004-06-10 Gillis Scott H. Prophylactic treatment methods
JP3741117B2 (en) * 2003-09-26 2006-02-01 住友金属鉱山株式会社 Mutual separation of platinum group elements
US20050131522A1 (en) * 2003-12-10 2005-06-16 Stinson Jonathan S. Medical devices and methods of making the same
US20060276875A1 (en) * 2005-05-27 2006-12-07 Stinson Jonathan S Medical devices

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB720025A (en) * 1950-12-22 1954-12-08 Georg Stetter Improvements in or relating to catalysts
GB1134492A (en) * 1964-03-11 1968-11-27 Johnson Matthey Co Ltd Methods of improving the mechanical properties of metals and their alloys
JPH01119595A (en) * 1987-11-02 1989-05-11 Tanaka Kikinzoku Kogyo Kk Material for single crystal growing crucible
US5800511A (en) * 1993-01-19 1998-09-01 Schneider (Usa) Inc Clad composite stent
US6152869A (en) * 1997-12-24 2000-11-28 Korea Atomic Research Energy Research Institute Radioactive stent and process for preparation thereof
US6340368B1 (en) * 1998-10-23 2002-01-22 Medtronic Inc. Implantable device with radiopaque ends
US20040025986A1 (en) * 2002-08-08 2004-02-12 Perry Andrew C. Controlled-grain-precious metal sputter targets
WO2005044361A1 (en) * 2003-11-07 2005-05-19 Merlin Md Pte Ltd Implantable medical devices with enhanced visibility, mechanical properties and biocompatibility
JP2005287568A (en) * 2004-03-31 2005-10-20 Homuzu Giken:Kk Stent

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; AN 1989-181979, XP002398329 *
DATABASE WPI Derwent World Patents Index; AN 2005-681298, XP002398325 *
PATENT ABSTRACTS OF JAPAN vol. 013, no. 362 (C - 625) 14 August 1989 (1989-08-14) *
PATENT ABSTRACTS OF JAPAN vol. 2003, no. 12 5 December 2003 (2003-12-05) *

Also Published As

Publication number Publication date
JP2008539812A (en) 2008-11-20
EP1885902B1 (en) 2010-05-05
WO2006119116A2 (en) 2006-11-09
US20060247758A1 (en) 2006-11-02
EP1885902A2 (en) 2008-02-13
DE602006014135D1 (en) 2010-06-17
US7309353B2 (en) 2007-12-18
ATE466967T1 (en) 2010-05-15

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