WO2006124749A3 - Multilayer drug delivery system with barrier against antagonist exposure - Google Patents

Multilayer drug delivery system with barrier against antagonist exposure Download PDF

Info

Publication number
WO2006124749A3
WO2006124749A3 PCT/US2006/018683 US2006018683W WO2006124749A3 WO 2006124749 A3 WO2006124749 A3 WO 2006124749A3 US 2006018683 W US2006018683 W US 2006018683W WO 2006124749 A3 WO2006124749 A3 WO 2006124749A3
Authority
WO
WIPO (PCT)
Prior art keywords
delivery system
drug delivery
barrier against
antagonist
multilayer drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/018683
Other languages
French (fr)
Other versions
WO2006124749A2 (en
Inventor
Rolf R Jansen
Dina J Coronado
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Priority to EP06759817A priority Critical patent/EP1898891A2/en
Publication of WO2006124749A2 publication Critical patent/WO2006124749A2/en
Publication of WO2006124749A3 publication Critical patent/WO2006124749A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F2013/0296—Apparatus or processes for manufacturing adhesive dressings or bandages for making transdermal patches (chemical processes excluded)

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A multilayered drug delivery system with a barrier suitable for delivery of drug through an individual's body surface with antagonist to the drug in the device. By placing a barrier between two adjacent layers to shield the antagonist, unintended antagonist flow due to migration of an antagonist matrix between the adjacent matrix layers in the system to a patient is avoided.
PCT/US2006/018683 2005-05-13 2006-05-12 Multilayer drug delivery system with barrier against antagonist exposure Ceased WO2006124749A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06759817A EP1898891A2 (en) 2005-05-13 2006-05-12 Multilayer drug delivery system with barrier against antagonist exposure

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68090505P 2005-05-13 2005-05-13
US60/680,905 2005-05-13
US79033806P 2006-04-07 2006-04-07
US60/790,338 2006-04-07

Publications (2)

Publication Number Publication Date
WO2006124749A2 WO2006124749A2 (en) 2006-11-23
WO2006124749A3 true WO2006124749A3 (en) 2007-05-31

Family

ID=36928781

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/018683 Ceased WO2006124749A2 (en) 2005-05-13 2006-05-12 Multilayer drug delivery system with barrier against antagonist exposure

Country Status (3)

Country Link
US (1) US20060257460A1 (en)
EP (1) EP1898891A2 (en)
WO (1) WO2006124749A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005515960A (en) * 2001-05-11 2005-06-02 エンドー ファーマシューティカルズ， インコーポレイティド Abuse-resistant opioid dosage form
US7815934B2 (en) 2002-09-20 2010-10-19 Alpharma Pharmaceuticals, Llc Sequestering subunit and related compositions and methods
ATE478659T1 (en) * 2005-05-13 2010-09-15 Alza Corp MULTI-LAYER MEDICINAL DELIVERY SYSTEM WITH BLOCK AGAINST RESERVOIR MATERIAL FLOW
WO2007121949A1 (en) * 2006-04-21 2007-11-01 LABTEC Gesellschaft für technologische Forschung und Entwicklung mbH Transdermal delivery system comprising sufentanil and its analogues
SI2719378T1 (en) 2006-06-19 2016-11-30 Alpharma Pharmaceuticals Llc Pharmaceutical compositions
AR063619A1 (en) * 2006-12-18 2009-02-04 Alcon Res Ltd DEVICES AND METHODS FOR THE ADMINISTRATION OF AN OPHTHALMIC DRUG
US20080293127A1 (en) * 2007-05-22 2008-11-27 Applera Corporation Method to Render Pressure Sensitive Adhesive Compatible with Polymerase Chain Reaction Systems
US8623418B2 (en) 2007-12-17 2014-01-07 Alpharma Pharmaceuticals Llc Pharmaceutical composition
US20090297590A1 (en) * 2008-05-30 2009-12-03 Masahiro Yamaji Ketotifen transdermal drug delivery systems and methods for treating ophthalmic disease
US20100221313A1 (en) * 2008-12-01 2010-09-02 Innovative Pharmaceuticals, Llc Transdermal reservoir patch
SE534196C2 (en) * 2009-06-29 2011-05-31 John Wollin Nicotine dosing system
US10010543B1 (en) 2014-12-23 2018-07-03 Barr Laboratories, Inc. Transdermal dosage form
GB201600920D0 (en) * 2016-01-18 2016-03-02 Buzzz Pharmaceuticals Ltd Transdermal patch
WO2020008370A1 (en) * 2018-07-02 2020-01-09 Clexio Biosciences Ltd. Transdermal patch
CN115363861A (en) * 2022-10-10 2022-11-22 青岛大学附属医院 Aseptic gauze subsides of easily opening of local anesthesia

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370924A (en) * 1989-12-14 1994-12-06 Pharmetrix Corporation Method for manufacturing transdermal devices
WO2002087482A1 (en) * 2001-05-01 2002-11-07 Euro-Celtique Abuse resistant opioid containing transdermal systems
WO2003090729A1 (en) * 2002-04-23 2003-11-06 Alza Corporation Transdermal analgesic systems with reduced abuse potential
WO2005018517A1 (en) * 2003-08-15 2005-03-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5370924A (en) * 1989-12-14 1994-12-06 Pharmetrix Corporation Method for manufacturing transdermal devices
WO2002087482A1 (en) * 2001-05-01 2002-11-07 Euro-Celtique Abuse resistant opioid containing transdermal systems
WO2003090729A1 (en) * 2002-04-23 2003-11-06 Alza Corporation Transdermal analgesic systems with reduced abuse potential
WO2005018517A1 (en) * 2003-08-15 2005-03-03 Mylan Technologies, Inc. Transdermal patch incorporating active agent migration barrier layer

Also Published As

Publication number Publication date
WO2006124749A2 (en) 2006-11-23
EP1898891A2 (en) 2008-03-19
US20060257460A1 (en) 2006-11-16

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