WO2006131781A1 - Device for collection of animal semen adaptable to an artificial vagina - Google Patents
Device for collection of animal semen adaptable to an artificial vagina Download PDFInfo
- Publication number
- WO2006131781A1 WO2006131781A1 PCT/IB2005/002314 IB2005002314W WO2006131781A1 WO 2006131781 A1 WO2006131781 A1 WO 2006131781A1 IB 2005002314 W IB2005002314 W IB 2005002314W WO 2006131781 A1 WO2006131781 A1 WO 2006131781A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- collection
- filtration
- frame
- semen
- artificial vagina
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
- A61D19/00—Instruments or methods for reproduction or fertilisation
- A61D19/02—Instruments or methods for reproduction or fertilisation for artificial insemination
- A61D19/021—Apparatus for collecting seminal fluids; Artificial vaginas
Definitions
- This invention relates to the collection of animal semen. It has for object a novel device for collection of animal semen, which is adaptable to an artificial vagina and which makes possible a filtration of the animal semen collected. This collection device is preferably for single usage .
- More sophisticated artificial vaginas are also known that make possible an automated stimulation of the penis, in particular by means of a variable pressure chamber fed by a fluid such as water or air.
- a fluid such as water or air.
- WO 02/13723 discloses an artificial vagina implementing an air-tight air chamber and making possible a localized stimulation of the penis of the animal by means of pulsations.
- the French patent FR 946 822 describes another known variant of embodiment of an artificial vagina for the collection of animal semen implementing a pressure chamber filled with water or air. Whatever the structure of the artificial vagina used for the collection of the animal semen, it is necessary to associate with this artificial vagina a collection system into which the semen flows, as it exits the artificial vagina.
- this collection system is for example (figure 1) a cylindrical tube which is fitted into the tubular end of the foam artificial vagina. This collection tube comprises more particularly a cylindrical part that is closed, opposite the artificial vagina, by a conical part into which the sampled semen flows.
- the collection system is in two parts : a cylindrical tube open at both ends and fitted to the outlet of the artificial vagina; a separate receptacle.
- the collection system is a rigid receptacle inserted in the end of the tube of the artificial vagina and held in position by ligatures.
- Animal semen essentially comprises two different substances: a liquid substance and a substance forming a sort of gel and commonly designated "tapioca".
- the liquid substance essentially comprises three liquid fractions: a first liquid fraction is essentially made up of urine containing bacteria ; a second liquid fraction, also commonly designated as the “rich fraction” is a creamy liquid containing spermatozoa ; a third liquid fraction is the so-called “seminal fluid” which nourishes spermatozoa of the rich fraction.
- the so-called rich fraction is the fraction useful for the artificial insemination after the collecting step.
- the "tapioca” is in return useless for insemination. It is therefore necessary to separate the "tapioca” from the liquid fractions of the semen.
- This invention has the principal objective of proposing a novel device for the collection of animal semen, which is adaptable to an artificial collection vagina, and which makes it possible to filter the animal semen.
- An auxiliary objective of the invention is to propose a device for the collection of animal semen, which makes it possible to avoid any risk of contact of the animal semen, and in particular of the liquid fractions, with an outside element, and in particular with the operator handling the collecting and/or with the animal and/or with the surrounding air that might be polluted, thus improving the hygiene conditions of the collecting operation.
- Another auxiliary objective of the invention is to propose a device for collection of animal semen, with an improved filtration of the animal semen avoiding the risk of clogging of the filtration medium by the "tapioca".
- Another auxiliary objective of the invention is to propose a single-use device for collection of animal semen.
- the device for collection of animal semen of the invention principally comprises a frame that is adaptable to an artificial vagina and to which are fixed means for filtration and a collection receptacle, the means of filtration being positioned inside the collection receptacle .
- the frame of the device of the invention fulfils a double function: it makes it possible to easily and rapidly adapt the device to the outlet of an artificial vagina; it serves as a common support for the means of filtration and for the collection receptacle.
- the invention has for object both an artificial vagina and a device for collection of animal semen, the collection device being adaptable, preferably in a removable way, to the artificial vagina.
- FIG. 1 is a perspective depiction of a collection device designed in accordance with a preferred variant of embodiment of the invention, and of the tubular end (outlet) of an artificial collection vagina designed to be assembled with said collection device,
- figure 2 is a perspective depiction of the part constituting the frame of the collection device of figure
- FIG. 3 is a longitudinal section view in the plane III-III of the frame of figure 2
- FIG. 4 is a longitudinal section view in the plane IV-IV of the frame of figure 2
- FIG 5 is a perspective depiction of the fixation ring of the collection device of figure 1
- - figure 6 is a detail of a cross-section view of the fixation ring of figure 5 and of the adaptation ring of the device of figure 1
- figure 7 is a longitudinal section view of the collection device and of the artificial vagina of figure 1, when they are assembled.
- FIG 1 there is a depiction of a preferred variant of embodiment of a device 1 for the collection of animal semen, which is for a single use "and which is adaptable to an artificial collection vagina V, so as to recover the animal semen as it comes out of this vagina.
- Figure 7 depicts schematically the collection device 1 assembled with the artificial vagina V.
- the vagina V was depicted in a very schematic way by a tubular element, knowing that the structure of this vagina V is without importance for the invention.
- the invention can in fact be implemented with any type of artificial collection vagina that makes it possible to stimulate the penis of an animal (in particular, boar, bull, stallion, rabbit, etc.).
- the collection device 1 can be designed to be adapted to a single-use manual artificial vagina of very simple structure of the type described for example in the French patent FR 946 822.
- the collection device 1 can also be designed to be adapted to a more sophisticated artificial vagina of the type described for example in the International Patent Application WO 02/13723.
- the collection device 1 comprises a rigid frame 2, means of filtration 3, a' receptacle 4, and a fixation ring 5.
- the rigid frame 2 is made up of an adaptation ring 20 delimiting an inner passage 21 for the flow of the animal semen (arrow F) from the artificial vagina, and of an armature 22 that is approximately U- shaped, which extends in the direction of the flow of semen.
- the adaptation ring 20 is mounted to the outlet of the artificial vagina V, the inner passage 21 communicates with and extends the inner cavity of the artificial vagina V.
- the geometry of the adaptation ring 20 is determined as a function of the geometry of the outlet of the artificial collection vagina V to which the collection device 1 is to be mounted. Under the circumstances, the outlet of the vagina V being cylindrical, the ring 20 presents a circular section.
- the invention is not, however, limited to the implementation of a ring with circular section, said ring can be replaced by any adaptation part delimiting a passage for the flow of the semen and presenting a geometry adapted to the outlet of the artificial collection vagina to which the collection device of the invention is to be mounted.
- the adaptation ring 20 comprises, on the outer wall 20b, two diametrically opposed assembly catches 23.
- these assemblage catches 23 are designed to respectively work together with the cut-outs D contrived in the artificial vagina V, so as to make possible rapid bayonet-type assembly.
- the invention is not limited to this particular structure of rapid assembly means, the catches 23 and cut-outs D can be replaced by any known type of rapid assembly means that make possible a blockage of the translation of the ring 20 with respect to the vagina V.
- the assembly of the ring 20 with the artificial vagina V could be obtained by a simple fitting together with tightening.
- the frame 2 (adaptation ring 20 / armature 22 / catches 23) is a one-piece part, for example made of plastic.
- the filtration means 3 ' are made up of a filtration medium made of textile, and more particularly by non-woven fabric, forming a filtration pouch.
- the function of these filtration means 3 is to block "tapioca" inside the filtration pouch, and to let the liquid fractions of the semen, including the "rich fraction” containing the spermatozoa, pass into the collection receptacle 4.
- the type of fibres constituting the non-woven fabric is without importance for the invention.
- the fibres of the non-woven filtration fabric 3 can for example be synthetic fibres made of polypropylene, polyethylene, etc., and/or natural cotton fibres, and/or artificial fibres of the viscous type.
- non-woven fabric to effect the filtration makes it possible to best advantage to manufacture a single-use filter.
- the invention is, however, not limited to the implementation of a non-woven fabric.
- the jion-woven filtration fabric 3 can be replaced by any equivalent filtration means that make it possible to separate the tapioca from the rest of the animal semen.
- the non-woven filtration fabric 3 is fixed to the frame 2, for example by being glued and/or joined over the entire periphery of the interior wall 20a of the adaptation ring 20, and by being glued and/or joined to the arms 22a, 22b and 22c of the U-shaped armature 22. More preferably, to simplify manufacturing, the non-woven fabric 3 is formed of two identical parts 30, 31 symmetrical to each other.
- the frame 2 makes it possible to best advantage to form, with the non-woven filtration fabric 3, a filtration cone (figure 3) . This filtration cone comprises an opening for the entry of semen of circular section corresponding to the inner section of the adaptation ring 20.
- the armature 22 makes it possible to best advantage to maintain the shape of the filtration pouch 3 over its entire height h.
- the length (1) of the arm 22a forming the base of the U of the armature 22 is slightly less than the inner diameter of the adaptation ring 20, and the two diametrically opposed lateral arms 22b and 22c of the armature 22 are slightly divergent with respect to each other in the direction of the adaptation ring 20, which makes it possible to confer on the filtration pouch 3 the shape of a funnel (cone) .
- the invention is, however, not limited to a ⁇ -shaped armature with divergent lateral arms, but can be replaced by any type of armature that makes it possible to maintain the shape of the filtration pouch over its entire height.
- the two lateral arms 22b and 22c of armature 22 can be approximately parallel.
- Receptacle 4 is to best advantage a single-use flexible collection pouch, for example made of plastic.
- this collection pouch 4 has a tubular shape, is open at one end 40 and closed at the opposite end 41.
- This collection pouch 4 is slipped onto the adaptation ring 20 by being fixed to the outer wall 20b of this ring 20.
- the filtration pouch 3 is thus seated inside the collection pouch 4, the two pouches 3 and 4 not being fixed to each other.
- fixation of the collection pouch 4 to the adaptation ring 20 is effected by means of the fixation ring 5, which is slipped onto and fixed to the adaptation ring 20, the collection pouch 4 being slipped on and wedged between the two rings 20 and 5.
- the fixation ring 5 comprises two diametrically opposed internal lugs 50 that work together with a peripheral groove 20c contrived in the outer wall 20b of the adaptation ring 20, so as to make possible the blocking in position of the fixation ring 5 with respect to the adaptation ring 20.
- the fixation ring 5 comprises two diametrically opposed internal lugs 50 that work together with a peripheral groove 20c contrived in the outer wall 20b of the adaptation ring 20, so as to make possible the blocking in position of the fixation ring 5 with respect to the adaptation ring 20.
- FIG 5 only one of the two lugs 50 is visible, the other, opposing, lug being masked.
- Manufacture of the collection device is done in the following way.
- the filtration cone of figure 3 is manufactured (assembly of the non-woven filtration fabric 3 to frame 2) .
- the collection pouch 4 is positioned by slipping it onto the adaptation ring 20 of frame 2 of this filtration cone.
- the fixation ring 5 is put in place by slipping and fitting it onto the adaptation ring 20 in such a way that the lugs 50 are positioned inside the groove 20c of the ring 20.
- the collection pouch 4 is immobilized by being wedged between the two rings 20 and 5. It should be noted that, for the sake of simplification, the collection pouch 4 is not depicted in figure 6.
- the lugs 50 and the groove 20c could be replaced by any equivalent means that make it possible to hermetically fix the collection pouch 4 to the adaptation ring 20.
- the fixation ring 5 could be eliminated and replaced by gluing and/or heat-sealing the collection pouch 4 to the adaptation ring 20.
- the collection pouch 4 comprises a peripheral pre-cutout line 42 (figure 1) , positioned in proximity to the adaptation ring 20, and that makes it possible to easily separate the collection pouch 4 into two parts, once the animal semen has been collected.
- the collection device 1 of the invention of which a preferred variant of embodiment was described with reference to the appended figures, is used in the following way.
- the collection device 1 Prior to the operation of collection of animal semen, the collection device 1 is assembled to the artificial collection vagina V.
- the artificial vagina V is slipped onto the penis of the animal (boar, bull, rabbit, etc.), and the customary operation of sampling of the animal semen is carried out, by stimulating the penis of the animal in a self-evident way by means of this artificial vagina V.
- the stimulation may be manual or automatic (pressure chamber fed by a fluid) .
- the animal When the animal has expelled its semen by ejaculation, the latter flows into the inside of the filtration cone (2, 3) of the collection device of the invention.
- the artificial vagina V equipped with collection device 1 is withdrawn, and, if need be, all of the animal semen is allowed to flow by gravity into the filtration cone (2, 3) of collection device 1.
- the non-woven fabric filter 3 of the filtration cone blocks the "tapioca” and allows the liquid fractions of the semen, including the "rich fraction" containing reproductive spermatozoa, to pass. Said liquid fractions flow by gravity into the collection pouch 4 by passing through the non-woven fabric filter.
- the non-woven filtration fabric 3 being held in shape by frame 2, the "tapioca” falls and accumulates to best advantage in the bottom of the non- woven fabric filter 3 (i.e., in the region of arm 22a of frame 2) without clogging the filter.
- This accumulation of "tapioca” in the bottom of the non-woven fabric filter 3 does not create an obstacle to the passage of the liquid fractions of the semen through the non-woven fabric wall of the filter.
- filtration is improved by avoiding the risk of formation of clogs by the "tapioca".
- the collection pouch 4 is manually cut out, following the pre- cutout line 42, so as to detach the part of pouch 4 containing the liquid fractions and located below the pre- cutout line 42.
- the operation of collection of the liquid fractions (including the "rich fraction") of the semen is then finished.
- all these collection operations are performed under optimal hygiene conditions by avoiding any risk of contact of the animal semen with an element exterior to the artificial vagina and the collection device, and in particular with the operator who is performing the collection, and/or with the animal, and/or with the surrounding air that might be polluted.
- the collection device 1 of the invention is removable with respect to the artificial vagina, such as in the examples illustrated in figure 1, once the above- mentioned collection operations have been performed, the collection device 1 containing the "tapioca" is withdrawn and it is discarded when this device is for single use.
- the collection device 1 of the invention be removable with respect to the artificial vagina, when said vagina is not for single use and is to be reused, and/or when it is desirable to recover the collection device 1 for a new use. In the other cases
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Reproductive Health (AREA)
- Public Health (AREA)
- Orthopedics, Nursing, And Contraception (AREA)
- Prostheses (AREA)
- Surgical Instruments (AREA)
- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Description
Claims
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2008515300A JP2008545496A (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to artificial vagina |
| CN200580050043XA CN101212936B (en) | 2005-06-08 | 2005-06-08 | Device for collecting animal semen suitable for artificial vagina |
| EP05768380A EP1895933B1 (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to an artificial vagina |
| ES05768380T ES2338024T3 (en) | 2005-06-08 | 2005-06-08 | DEVICE FOR THE COLLECTION OF ANIMAL SEMEN ADAPTABLE TO AN ARTIFICIAL VAGINA. |
| PCT/IB2005/002314 WO2006131781A1 (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to an artificial vagina |
| BRPI0520386-4A BRPI0520386B1 (en) | 2005-06-08 | 2005-06-08 | DEVICE FOR ANIMAL SPERM COLLECTION AND ARTIFICIAL VAGINA |
| AT05768380T ATE451074T1 (en) | 2005-06-08 | 2005-06-08 | ANIMAL SEMEN COLLECTION DEVICE ADAPABLE TO AN ARTIFICIAL VAGINA |
| US11/921,525 US9370410B2 (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to an artificial vagina |
| DE602005018268T DE602005018268D1 (en) | 2005-06-08 | 2005-06-08 | DEVICE FOR CATCHING TIERSPERMA ADAPTABLE TO AN ARTIFICIAL VAGINA |
| CA2610983A CA2610983C (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to an artificial vagina |
| DK05768380.7T DK1895933T3 (en) | 2005-06-08 | 2005-06-08 | Animal semen collection device which can be adapted to an artificial vagina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2005/002314 WO2006131781A1 (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to an artificial vagina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2006131781A1 true WO2006131781A1 (en) | 2006-12-14 |
Family
ID=35695797
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/IB2005/002314 Ceased WO2006131781A1 (en) | 2005-06-08 | 2005-06-08 | Device for collection of animal semen adaptable to an artificial vagina |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9370410B2 (en) |
| EP (1) | EP1895933B1 (en) |
| JP (1) | JP2008545496A (en) |
| CN (1) | CN101212936B (en) |
| AT (1) | ATE451074T1 (en) |
| BR (1) | BRPI0520386B1 (en) |
| CA (1) | CA2610983C (en) |
| DE (1) | DE602005018268D1 (en) |
| DK (1) | DK1895933T3 (en) |
| ES (1) | ES2338024T3 (en) |
| WO (1) | WO2006131781A1 (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3572039A1 (en) | 2018-05-24 | 2019-11-27 | IMV Technologies | Device for collection of animal semen |
| EP3572038A1 (en) | 2018-05-24 | 2019-11-27 | IMV Technologies | Device for collecting animal semen |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004053796B4 (en) * | 2004-11-08 | 2007-03-01 | Minitüb Abfüll - und Labortechnik GmbH & Co KG | Method and device for the semen collection |
| CN202005873U (en) * | 2011-02-22 | 2011-10-12 | 爱侣健康科技有限公司 | Sperm retrieval device with extruding function |
| US10154832B2 (en) * | 2014-11-19 | 2018-12-18 | Danzhi Cai | Semen collection device |
| USD867611S1 (en) * | 2018-01-29 | 2019-11-19 | Sandstone Diagnostics, Inc. | Sample cup |
| US10973617B2 (en) * | 2018-03-27 | 2021-04-13 | Bruce Eilts | Artificial vagina set |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR946822A (en) | 1947-05-16 | 1949-06-15 | Semen collector artificial vagina | |
| US4690678A (en) * | 1984-03-12 | 1987-09-01 | 501 Hamilton/Thorn Research Associates | Device and method for facilitating animal artificial insemination |
| EP0699422A1 (en) | 1994-09-02 | 1996-03-06 | Societe D'etudes, De Gestion, D'engineering | Disposable semen collection device for animals, in particular for boars and rabbits |
| US5961503A (en) * | 1998-05-13 | 1999-10-05 | Minitube Of America, Inc. | Boar semen collection bag |
| WO2002013723A1 (en) | 2000-08-11 | 2002-02-21 | Genes Diffusion | Animal device for collecting an animal's seminal fluid |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2154671Y (en) * | 1993-05-12 | 1994-02-02 | 李东 | Artificial enimal seminal liquid collector |
| DE29504115U1 (en) * | 1995-03-09 | 1996-07-11 | Maxs Ag, Sachseln | Kit for a filter coffee maker |
| DE59700148D1 (en) * | 1997-03-13 | 1999-06-02 | Braun Ag | Filtration device, filter element and method for producing the filter element which is used to produce brewed beverages |
| US6267776B1 (en) * | 1999-05-03 | 2001-07-31 | O'connell Paul T. | Vena cava filter and method for treating pulmonary embolism |
| GB0020901D0 (en) * | 2000-08-25 | 2000-10-11 | Smiths Industries Plc | Ostomy bags |
| US7156098B2 (en) * | 2004-03-19 | 2007-01-02 | Dolezal Creative Innovations, Llc | Breathing air filtration system |
| US20060234210A1 (en) * | 2004-04-14 | 2006-10-19 | Affinergy, Inc. | Filtration device and method for removing selected materials from biological fluids |
-
2005
- 2005-06-08 US US11/921,525 patent/US9370410B2/en active Active
- 2005-06-08 DK DK05768380.7T patent/DK1895933T3/en active
- 2005-06-08 CA CA2610983A patent/CA2610983C/en not_active Expired - Lifetime
- 2005-06-08 EP EP05768380A patent/EP1895933B1/en not_active Expired - Lifetime
- 2005-06-08 DE DE602005018268T patent/DE602005018268D1/en not_active Expired - Lifetime
- 2005-06-08 JP JP2008515300A patent/JP2008545496A/en active Pending
- 2005-06-08 CN CN200580050043XA patent/CN101212936B/en not_active Expired - Fee Related
- 2005-06-08 AT AT05768380T patent/ATE451074T1/en not_active IP Right Cessation
- 2005-06-08 BR BRPI0520386-4A patent/BRPI0520386B1/en not_active IP Right Cessation
- 2005-06-08 WO PCT/IB2005/002314 patent/WO2006131781A1/en not_active Ceased
- 2005-06-08 ES ES05768380T patent/ES2338024T3/en not_active Expired - Lifetime
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR946822A (en) | 1947-05-16 | 1949-06-15 | Semen collector artificial vagina | |
| US4690678A (en) * | 1984-03-12 | 1987-09-01 | 501 Hamilton/Thorn Research Associates | Device and method for facilitating animal artificial insemination |
| EP0699422A1 (en) | 1994-09-02 | 1996-03-06 | Societe D'etudes, De Gestion, D'engineering | Disposable semen collection device for animals, in particular for boars and rabbits |
| US5961503A (en) * | 1998-05-13 | 1999-10-05 | Minitube Of America, Inc. | Boar semen collection bag |
| WO2002013723A1 (en) | 2000-08-11 | 2002-02-21 | Genes Diffusion | Animal device for collecting an animal's seminal fluid |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3572039A1 (en) | 2018-05-24 | 2019-11-27 | IMV Technologies | Device for collection of animal semen |
| EP3572038A1 (en) | 2018-05-24 | 2019-11-27 | IMV Technologies | Device for collecting animal semen |
| FR3081292A1 (en) * | 2018-05-24 | 2019-11-29 | Imv Technologies | ANIMAL SEMEN COLLECTION DEVICE |
| FR3081321A1 (en) * | 2018-05-24 | 2019-11-29 | Imv Technologies | ANIMAL SEED COLLECTION DEVICE |
| US11259909B2 (en) | 2018-05-24 | 2022-03-01 | Imv Technologies | Device for collecting animal semen |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101212936B (en) | 2010-09-15 |
| EP1895933A1 (en) | 2008-03-12 |
| US20090137974A1 (en) | 2009-05-28 |
| BRPI0520386B1 (en) | 2017-10-31 |
| JP2008545496A (en) | 2008-12-18 |
| CN101212936A (en) | 2008-07-02 |
| BRPI0520386A2 (en) | 2009-05-05 |
| EP1895933B1 (en) | 2009-12-09 |
| DK1895933T3 (en) | 2010-02-15 |
| US9370410B2 (en) | 2016-06-21 |
| CA2610983A1 (en) | 2006-12-14 |
| ATE451074T1 (en) | 2009-12-15 |
| CA2610983C (en) | 2012-08-14 |
| ES2338024T3 (en) | 2010-05-03 |
| DE602005018268D1 (en) | 2010-01-21 |
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