WO2006133396A3 - Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway - Google Patents

Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway Download PDF

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Publication number
WO2006133396A3
WO2006133396A3 PCT/US2006/022423 US2006022423W WO2006133396A3 WO 2006133396 A3 WO2006133396 A3 WO 2006133396A3 US 2006022423 W US2006022423 W US 2006022423W WO 2006133396 A3 WO2006133396 A3 WO 2006133396A3
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WO
WIPO (PCT)
Prior art keywords
cancer
compositions
methods
treatment
pathway
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/022423
Other languages
French (fr)
Other versions
WO2006133396A2 (en
Inventor
Gordan Freeman
Arlene Sharpe
David M Dorfman
Rafi Ahmed
Daniel Barber
E John Wherry
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Dana Farber Cancer Institute Inc
Emory University
Original Assignee
Brigham and Womens Hospital Inc
Dana Farber Cancer Institute Inc
Emory University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37499143&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2006133396(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to MX2015000025A priority Critical patent/MX351401B/en
Priority to NZ564243A priority patent/NZ564243A/en
Priority to EP23163877.6A priority patent/EP4242655A3/en
Priority to AU2006254902A priority patent/AU2006254902B8/en
Priority to EP06784684.0A priority patent/EP1907000B2/en
Priority to ES06784684T priority patent/ES2397355T5/en
Priority to PL06784684T priority patent/PL1907000T5/en
Priority to KR1020147003918A priority patent/KR101510065B1/en
Priority to CA2611861A priority patent/CA2611861C/en
Priority to KR1020147028424A priority patent/KR101600225B1/en
Priority to KR1020087000548A priority patent/KR101514463B1/en
Priority to BRPI0611766-0A priority patent/BRPI0611766A2/en
Priority to DK06784684.0T priority patent/DK1907000T4/en
Application filed by Brigham and Womens Hospital Inc, Dana Farber Cancer Institute Inc, Emory University filed Critical Brigham and Womens Hospital Inc
Priority to KR1020167004817A priority patent/KR101804078B1/en
Priority to HK08111142.6A priority patent/HK1115326B/en
Priority to SI200631501T priority patent/SI1907000T2/en
Priority to JP2008515956A priority patent/JP5788632B2/en
Priority to MX2012004075A priority patent/MX349137B/en
Publication of WO2006133396A2 publication Critical patent/WO2006133396A2/en
Publication of WO2006133396A3 publication Critical patent/WO2006133396A3/en
Anticipated expiration legal-status Critical
Priority to IL187999A priority patent/IL187999A/en
Priority to ZA2007/10975A priority patent/ZA200710975B/en
Priority to IL230396A priority patent/IL230396A/en
Priority to IL236806A priority patent/IL236806A/en
Priority to IL236805A priority patent/IL236805B/en
Priority to IL257622A priority patent/IL257622B/en
Ceased legal-status Critical Current

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Abstract

The present invention provides methods and compositions for the treatment, prevention, or reduction of persistent infections, such as chronic infections, latent infections, and slow infections and cancer. The methods and compositions of the invention are also useful for the alleviation of one or more symptoms associated with such infections and cancer.
PCT/US2006/022423 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway Ceased WO2006133396A2 (en)

Priority Applications (24)

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BRPI0611766-0A BRPI0611766A2 (en) 2005-06-08 2006-06-08 methods and compositions for the treatment of persistent infections and cancer by inhibition of the programmed cell death pathway
KR1020167004817A KR101804078B1 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
EP23163877.6A EP4242655A3 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1)pathway
AU2006254902A AU2006254902B8 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (PD-1) pathway
EP06784684.0A EP1907000B2 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1)pathway
ES06784684T ES2397355T5 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibition of the programmed cell death pathway (PD-1)
PL06784684T PL1907000T5 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent HIV infections by inhibiting the programmed cell death 1 (PD-1) pathway
KR1020147003918A KR101510065B1 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
CA2611861A CA2611861C (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections
KR1020147028424A KR101600225B1 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
KR1020087000548A KR101514463B1 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
NZ564243A NZ564243A (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections by inhibiting the programmed cell death 1 (PD-1) pathway
DK06784684.0T DK1907000T4 (en) 2005-06-08 2006-06-08 Methods and compositions for treating persistent HIV infections by inhibiting the pathway of programmed cell death 1 (PD-1).
MX2015000025A MX351401B (en) 2005-06-08 2006-06-08 METHODS AND COMPOSITIONS FOR THE TREATMENT OF PERSISTENT INFECTIONS AND CANCER BY INHIBITION OF THE PROGRAMMED CELL DEATH ROUTE (PD-1).
SI200631501T SI1907000T2 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent HIV infections by inhibiting the programmed cell death 1 (PD-1) pathway
MX2012004075A MX349137B (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway.
HK08111142.6A HK1115326B (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
JP2008515956A JP5788632B2 (en) 2005-06-08 2006-06-08 Methods and compositions for the treatment of persistent infection and cancer by inhibiting the programmed cell death 1 (PD-1) pathway
IL187999A IL187999A (en) 2005-06-08 2007-12-09 Use of an antibody that inhibits PD-1 activity in the preparation of a drug to relieve or prevent the symptom of stubborn viral infection, angioimmunoblastic lymphoma or predominant Hodgkin lymphoma lymphoma
ZA2007/10975A ZA200710975B (en) 2005-06-08 2007-12-18 Methods and compositions for the treatment of persistent infections and cancer by inhibiting the programmed cell death 1 (pd-1) pathway
IL230396A IL230396A (en) 2005-06-08 2014-01-09 Compounds that reduce the activity or expression of pd-1 polypeptide for use in the treatment of Hodgkin's lymphoma or angioimmunoblastic lymphoma
IL236805A IL236805B (en) 2005-06-08 2015-01-19 Use of an antibody that inhibits pd-1 activity in the preparation of a drug to relieve or prevent a symptom of persistent viral infection, angioimmunoblastic lymphoma or nodular lymphocyte predominant Hodgkin's lymphoma
IL236806A IL236806A (en) 2005-06-08 2015-01-19 Methods and Compounds for the Treatment of Stubborn Adhesion
IL257622A IL257622B (en) 2005-06-08 2018-02-20 Methods and preparations for the treatment of persistent infections

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US68887205P 2005-06-08 2005-06-08
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