WO2007001744A3 - Methods and compositions for enhancing vascular access - Google Patents

Methods and compositions for enhancing vascular access Download PDF

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Publication number
WO2007001744A3
WO2007001744A3 PCT/US2006/021755 US2006021755W WO2007001744A3 WO 2007001744 A3 WO2007001744 A3 WO 2007001744A3 US 2006021755 W US2006021755 W US 2006021755W WO 2007001744 A3 WO2007001744 A3 WO 2007001744A3
Authority
WO
WIPO (PCT)
Prior art keywords
implantable material
cells
methods
present
functional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/021755
Other languages
French (fr)
Other versions
WO2007001744A2 (en
WO2007001744B1 (en
Inventor
Helen Marie Nugent
Elazer Edelman
Anupam Dalal
Steve Bollinger
Scott Epperly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pervasis Therapeutics Inc
Original Assignee
Pervasis Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2005/043967 external-priority patent/WO2006062909A2/en
Priority to JP2008518189A priority Critical patent/JP5632580B2/en
Priority to AU2006262682A priority patent/AU2006262682B2/en
Priority to CN2006800279776A priority patent/CN101257861B/en
Priority to US11/922,729 priority patent/US20090035346A1/en
Priority to EP20060772165 priority patent/EP1901680B1/en
Priority to ES06772165.4T priority patent/ES2541684T3/en
Priority to CA 2612751 priority patent/CA2612751A1/en
Application filed by Pervasis Therapeutics Inc filed Critical Pervasis Therapeutics Inc
Publication of WO2007001744A2 publication Critical patent/WO2007001744A2/en
Publication of WO2007001744A3 publication Critical patent/WO2007001744A3/en
Priority to IL188263A priority patent/IL188263A/en
Publication of WO2007001744B1 publication Critical patent/WO2007001744B1/en
Anticipated expiration legal-status Critical
Priority to IL220806A priority patent/IL220806A/en
Priority to US13/667,227 priority patent/US9023377B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3808—Endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)

Abstract

Disclosed is an implantable material comprising a biocompatible matrix and cells which, when provided to a vascular access structure, can promote functionality generally. For example, implantable material of the present invention can enhance maturation of an arteriovenous native fistula as well as prolong the fistula in a mature, functional state suitable for dialysis. Additionally, the present invention can promote formation of a functional arteriovenous graft suitable for dialysis as well as promote formation of a functional peripheral bypass graft. Implantable material can be configured as a flexible planar form or a flowable composition with shape-retaining properties suitable for implantation at, adjacent or in the vicinity of an anastomoses or arteriovenous graft. According to the methods disclosed herein, the implantable material is provided to an exterior surface of a blood vessel. Certain embodiments of the flexible planar form define a slot. The materials and methods of the present invention comprise cells, preferably endothelial cells or cells having an endothelial-like phenotype.
PCT/US2006/021755 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access Ceased WO2007001744A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
JP2008518189A JP5632580B2 (en) 2005-06-21 2006-06-05 Methods and compositions for improving vascular access
AU2006262682A AU2006262682B2 (en) 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access
CN2006800279776A CN101257861B (en) 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access
US11/922,729 US20090035346A1 (en) 2005-06-21 2006-06-05 Methods and Compositions for Enhancing Vascular Access
EP20060772165 EP1901680B1 (en) 2005-06-21 2006-06-05 Crypreservation of biocompatible material
ES06772165.4T ES2541684T3 (en) 2005-06-21 2006-06-05 Cryopreservation of biocompatible material
CA 2612751 CA2612751A1 (en) 2005-06-21 2006-06-05 Vegf-containing transport media composition for storing cells engrafted in a biocompatible matrix
IL188263A IL188263A (en) 2005-06-21 2007-12-19 Transport media compositions for storing an implantable material and methods for storing an implantable material
IL220806A IL220806A (en) 2005-06-21 2012-07-05 Method and compositions for enhancing vascular access
US13/667,227 US9023377B2 (en) 2005-06-21 2012-11-02 Methods and compositions for enhancing vascular access

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69270805P 2005-06-21 2005-06-21
US60/692,708 2005-06-21
USPCT/US2005/043967 2005-12-06
PCT/US2005/043967 WO2006062909A2 (en) 2004-12-08 2005-12-06 Methods and compositions for enhancing vascular access

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/043967 Continuation WO2006062909A2 (en) 2004-12-08 2005-12-06 Methods and compositions for enhancing vascular access

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US11/922,729 A-371-Of-International US20090035346A1 (en) 2005-06-21 2006-06-05 Methods and Compositions for Enhancing Vascular Access
US13/667,227 Continuation US9023377B2 (en) 2005-06-21 2012-11-02 Methods and compositions for enhancing vascular access

Publications (3)

Publication Number Publication Date
WO2007001744A2 WO2007001744A2 (en) 2007-01-04
WO2007001744A3 true WO2007001744A3 (en) 2007-10-04
WO2007001744B1 WO2007001744B1 (en) 2007-12-21

Family

ID=39892157

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/021755 Ceased WO2007001744A2 (en) 2005-06-21 2006-06-05 Methods and compositions for enhancing vascular access

Country Status (10)

Country Link
US (2) US20090035346A1 (en)
EP (2) EP2361591A3 (en)
JP (2) JP5632580B2 (en)
CN (3) CN101878757A (en)
AU (1) AU2006262682B2 (en)
CA (2) CA2818182C (en)
ES (1) ES2541684T3 (en)
IL (2) IL188263A (en)
SG (2) SG161258A1 (en)
WO (1) WO2007001744A2 (en)

Cited By (1)

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US9884013B2 (en) 2011-04-28 2018-02-06 Abraxis Bioscience, Llc Intravascular delivery of nanoparticle compositions and uses thereof

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CA2605080A1 (en) 2005-04-21 2006-11-02 Massachusetts Institute Of Technology Materials and methods for altering an immune response to exogenous and endogenous immunogens, including syngeneic and non-syngeneic cells, tissues or organs
EP2361591A3 (en) 2005-06-21 2011-12-21 Pervasis Therapeutics, Inc. Methods and compositions for enhancing vascular access
JP5372764B2 (en) * 2006-11-07 2013-12-18 シャイア リジェネラティブ メディシン， インコーポレイテッド Materials and methods for the treatment and management of angiogenesis-related diseases
WO2008057590A2 (en) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Methods and compositions for modulating tissue modeling
EP2240116B1 (en) 2008-01-28 2015-07-01 Biomet 3I, LLC Implant surface with increased hydrophilicity
CN102763642B (en) * 2012-08-14 2014-04-02 郑州赛英科干细胞技术有限公司 Cryoprotectant and method for cryopreserving placenta amnion and chorion
AU2015265954A1 (en) * 2014-05-27 2017-01-12 Novahep Ab Bioengineered allogeneic valve
CA3222892A1 (en) * 2015-03-10 2016-09-15 Stent Tek Limited Surgical system, device and methods of use thereof for the percutaneous creation of an arteriovenous fistula (avf)
US11389622B1 (en) * 2017-11-13 2022-07-19 Simon B. Rayhanabad Patch for providing dialysis
US12017032B1 (en) 2017-11-13 2024-06-25 Sbr Innovations, Llc Arteriovenous graft and method of using thereof
WO2019152799A1 (en) 2018-02-02 2019-08-08 University Of Louisville Research Foundation, Inc. Sutureless graft anastomotic quick connect system
JP7669266B2 (en) * 2018-08-31 2025-04-28 ウィスコンシン アラムニ リサーチ ファンデーション Generation of vascular grafts seeded with arterial endothelial cells
US12310836B2 (en) 2020-03-03 2025-05-27 Akeo Hagiwara Vein cover
CN115376392B (en) * 2022-08-18 2024-04-26 昆明理工大学 Device and method for simulating influence of aortic aging on vascular biomechanics
EP4439070B1 (en) * 2023-03-27 2025-12-03 Siemens Healthcare Diagnostics Products GmbH Automatic analysis system
CN120227529B (en) * 2025-05-29 2025-08-12 鼎科医疗技术（苏州）有限公司 Extravascular stent

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US9884013B2 (en) 2011-04-28 2018-02-06 Abraxis Bioscience, Llc Intravascular delivery of nanoparticle compositions and uses thereof
US10258565B2 (en) 2011-04-28 2019-04-16 Abraxis Bioscience, Llc Intravascular delivery of nanoparticle compositions and uses thereof

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