WO2007002123A3 - Method and device for coating a continuous strip of microprojection members - Google Patents

Method and device for coating a continuous strip of microprojection members Download PDF

Info

Publication number
WO2007002123A3
WO2007002123A3 PCT/US2006/024036 US2006024036W WO2007002123A3 WO 2007002123 A3 WO2007002123 A3 WO 2007002123A3 US 2006024036 W US2006024036 W US 2006024036W WO 2007002123 A3 WO2007002123 A3 WO 2007002123A3
Authority
WO
WIPO (PCT)
Prior art keywords
agent
reservoir
coating
microprojection
formulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/024036
Other languages
French (fr)
Other versions
WO2007002123A2 (en
Inventor
Peter Daddona
John Dohner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Priority to AU2006262316A priority Critical patent/AU2006262316A1/en
Priority to JP2008518330A priority patent/JP2008546483A/en
Priority to EP06785214A priority patent/EP1898989A2/en
Priority to CA002612307A priority patent/CA2612307A1/en
Publication of WO2007002123A2 publication Critical patent/WO2007002123A2/en
Publication of WO2007002123A3 publication Critical patent/WO2007002123A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/20—Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205—Vaccinating by means of needles or other puncturing devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00526—Methods of manufacturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00893—Material properties pharmaceutically effective
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0053—Methods for producing microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)

Abstract

The present invention provides a device and method for selectively providing multiple applications of an agent formulation on the skin piercing portions of a micrÌprojection member to form an agent-containing coating on the microprojections. The formulation is dried to form a solid coating which contains the agent. A continuous conveyor strip bearing multiple microprojection members is spiral wrapped around a product drum so that each microprojection member is conveyed past a reservoir a plurality of times. The reservoir is configured to transfer an application of agent formulation onto the microprojection member each time it passes the reservoir.
PCT/US2006/024036 2005-06-21 2006-06-20 Method and device for coating a continuous strip of microprojection members Ceased WO2007002123A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2006262316A AU2006262316A1 (en) 2005-06-21 2006-06-20 Method and device for coating a continuous strip of microprojection members
JP2008518330A JP2008546483A (en) 2005-06-21 2006-06-20 Method and device for coating a continuous strip of microprojection members
EP06785214A EP1898989A2 (en) 2005-06-21 2006-06-20 Method and device for coating a continuous strip of microprojection members
CA002612307A CA2612307A1 (en) 2005-06-21 2006-06-20 Method and device for coating a continuous strip of microprojection members

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69276905P 2005-06-21 2005-06-21
US60/692,769 2005-06-21

Publications (2)

Publication Number Publication Date
WO2007002123A2 WO2007002123A2 (en) 2007-01-04
WO2007002123A3 true WO2007002123A3 (en) 2007-03-29

Family

ID=37595754

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/024036 Ceased WO2007002123A2 (en) 2005-06-21 2006-06-20 Method and device for coating a continuous strip of microprojection members

Country Status (7)

Country Link
US (1) US20070009587A1 (en)
EP (1) EP1898989A2 (en)
JP (1) JP2008546483A (en)
CN (1) CN101252967A (en)
AU (1) AU2006262316A1 (en)
CA (1) CA2612307A1 (en)
WO (1) WO2007002123A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9067048B2 (en) 2009-04-24 2015-06-30 Medrx Co., Ltd. Medication liquid supporting jig and method of applying medication to micro-needle using same

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7184826B2 (en) * 1996-06-18 2007-02-27 Alza Corporation Device and method for enhancing transdermal flux of agents being delivered or sampled
US7097631B2 (en) 2003-10-31 2006-08-29 Alza Corporation Self-actuating applicator for microprojection array
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
AU2006291157A1 (en) * 2005-09-12 2007-03-22 Alza Corporation Coatable transdermal delivery microprojection assembly
CN101466393A (en) * 2006-03-15 2009-06-24 阿尔扎公司 Method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
CA2695731C (en) * 2007-08-06 2018-04-03 Transderm, Inc. Microneedle arrays formed from polymer films
WO2009079712A1 (en) * 2007-12-24 2009-07-02 The University Of Queensland Coating method
WO2009097660A1 (en) 2008-02-07 2009-08-13 The University Of Queensland Patch production
CA2760680A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection by microneedle patch with analyte selective reagents
CN102325563A (en) 2008-12-22 2012-01-18 昆士兰大学 Patch production
WO2012006677A1 (en) 2010-07-14 2012-01-19 The University Of Queensland Patch applying apparatus
EP2765927B1 (en) 2011-10-12 2021-02-24 Vaxxas Pty Limited Delivery device
US20160279401A1 (en) 2015-03-27 2016-09-29 Allergan, Inc. Dissolvable microneedles for skin treatment
US11147954B2 (en) 2015-02-02 2021-10-19 Vaxxas Pty Limited Microprojection array applicator and method
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
US20180264244A1 (en) 2015-09-28 2018-09-20 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
KR102401856B1 (en) 2017-02-17 2022-05-26 알레간 인코포레이티드 Microneedle Array with Active Ingredient
AU2018241251B2 (en) 2017-03-31 2024-06-27 Vaxxas Pty Limited Device and method for coating surfaces
EP3639010B1 (en) 2017-06-13 2025-08-06 Vaxxas Pty Limited Quality control of substrate coatings
EP4548954A3 (en) 2017-08-04 2025-07-30 Vaxxas Pty Limited Compact high mechanical energy storage and low trigger force actuator for the delivery of microprojection array patches (map)
CN110076528A (en) * 2019-05-13 2019-08-02 大连理工大学 A kind of planar metal microneedle array and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19744367C1 (en) * 1997-10-08 1998-11-05 Schott Glas Simple application of thin, uniform silicone oil coating free from particles to medical cannula
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (en) * 1972-02-14 1973-08-13 Ici Ltd DRESSINGS
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
WO1996037155A1 (en) * 1995-05-22 1996-11-28 Silicon Microdevices, Inc. Micromechanical device and method for enhancing delivery of compounds through the skin
PT1037686E (en) * 1997-12-11 2005-10-31 Alza Corp APPARATUS FOR POTENTIATING THE FLOW OF TRANSDERMMIC AGENT
WO1999029364A1 (en) * 1997-12-11 1999-06-17 Alza Corporation Device for enhancing transdermal agent flux
US6091975A (en) * 1998-04-01 2000-07-18 Alza Corporation Minimally invasive detecting device

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19744367C1 (en) * 1997-10-08 1998-11-05 Schott Glas Simple application of thin, uniform silicone oil coating free from particles to medical cannula
US6855372B2 (en) * 2001-03-16 2005-02-15 Alza Corporation Method and apparatus for coating skin piercing microprojections

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9067048B2 (en) 2009-04-24 2015-06-30 Medrx Co., Ltd. Medication liquid supporting jig and method of applying medication to micro-needle using same

Also Published As

Publication number Publication date
WO2007002123A2 (en) 2007-01-04
EP1898989A2 (en) 2008-03-19
JP2008546483A (en) 2008-12-25
CN101252967A (en) 2008-08-27
AU2006262316A1 (en) 2007-01-04
CA2612307A1 (en) 2007-01-04
US20070009587A1 (en) 2007-01-11

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