WO2007018563A3 - Probe arrays for detecting multiple strains of different species - Google Patents

Probe arrays for detecting multiple strains of different species Download PDF

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Publication number
WO2007018563A3
WO2007018563A3 PCT/US2005/035471 US2005035471W WO2007018563A3 WO 2007018563 A3 WO2007018563 A3 WO 2007018563A3 US 2005035471 W US2005035471 W US 2005035471W WO 2007018563 A3 WO2007018563 A3 WO 2007018563A3
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WO
WIPO (PCT)
Prior art keywords
species
probes
present
different
probe arrays
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2005/035471
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French (fr)
Other versions
WO2007018563A2 (en
Inventor
William Martin Mounts
Ellen Murphy
Stephen Bruce Olmsted
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
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Wyeth LLC
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Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Priority to AU2005335216A priority Critical patent/AU2005335216A1/en
Priority to EP05858434A priority patent/EP1817432A2/en
Priority to CA002582137A priority patent/CA2582137A1/en
Priority to US11/348,413 priority patent/US20060160121A1/en
Publication of WO2007018563A2 publication Critical patent/WO2007018563A2/en
Anticipated expiration legal-status Critical
Publication of WO2007018563A3 publication Critical patent/WO2007018563A3/en
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides probe arrays and methods of using the same for concurrent and discriminable detection of multiple strains of different species. In one aspect, the probe arrays of the present invention are nucleic acid arrays comprising (1) a first group of probes, each of which is specific to a different respective strain of a first species; and (2) a second group of probes, each of which is specific to a different respective strain of a second species. In many embodiments, the nucleic acid arrays of the present invention further include a third group of probes, each of which is specific to a different strain of a third species. In one example, a nucleic acid array of the present invention includes probes for sequences selected from SEQ ID NOs: 1 to 18,598, and can discriminably detect different strains of Streptococcus pyogenes, Streptococcus agalactiae and Staphylococcus epidermidis.
PCT/US2005/035471 2004-10-05 2005-10-05 Probe arrays for detecting multiple strains of different species Ceased WO2007018563A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU2005335216A AU2005335216A1 (en) 2004-10-05 2005-10-05 Probe arrays for detecting multiple strains of different species
EP05858434A EP1817432A2 (en) 2004-10-05 2005-10-05 Probe arrays for detecting multiple strains of different species
CA002582137A CA2582137A1 (en) 2004-10-05 2005-10-05 Probe arrays for detecting multiple strains of different species
US11/348,413 US20060160121A1 (en) 2004-10-05 2006-02-07 Probe arrays for detecting multiple strains of different species

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61557304P 2004-10-05 2004-10-05
US60/615,573 2004-10-05

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US24344505A Continuation-In-Part 2004-10-05 2005-10-05

Publications (2)

Publication Number Publication Date
WO2007018563A2 WO2007018563A2 (en) 2007-02-15
WO2007018563A3 true WO2007018563A3 (en) 2007-06-21

Family

ID=36684340

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/035471 Ceased WO2007018563A2 (en) 2004-10-05 2005-10-05 Probe arrays for detecting multiple strains of different species

Country Status (5)

Country Link
US (1) US20060160121A1 (en)
EP (1) EP1817432A2 (en)
AU (1) AU2005335216A1 (en)
CA (1) CA2582137A1 (en)
WO (1) WO2007018563A2 (en)

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US8858957B2 (en) 2007-09-12 2014-10-14 Novartis Ag GAS57 mutant antigens and GAS57 antibodies
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae

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US6890539B2 (en) 1998-12-22 2005-05-10 Microscience, Ltd. Genes and proteins, and their use
US7491402B2 (en) * 1998-12-24 2009-02-17 Auckland Uniservices Limited Superantigens SMEZ-2, SPE-G, SPE-H and SPE-J and uses thereof
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US7709009B2 (en) * 2003-07-31 2010-05-04 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for streptococcus pyogenes
WO2006078318A2 (en) 2004-07-29 2006-07-27 Novartis Vaccines And Diagnostics Inc. Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
KR100850193B1 (en) * 2004-08-28 2008-08-04 주식회사 진인 Bacterial specific, genus specific and species specific oligonucleotides for the discrimination of all bacteria, diagnostic kits comprising the same, and detection methods using the same
EP1807446A2 (en) * 2004-10-08 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Immunogenic and therapeutic compositions for streptococcus pyogenes
US7531309B2 (en) * 2005-12-06 2009-05-12 Michigan State University PCR based capsular typing method
WO2007128109A1 (en) * 2006-05-04 2007-11-15 University Health Network Aptamers that recognize the carbohydrate n-acetylgalactosamine (galnac)
DK2054431T3 (en) * 2006-06-09 2012-01-02 Novartis Ag Conformers of bacterial adhesins
AU2007348285A1 (en) * 2006-10-30 2008-09-12 Novartis Ag Immunogenic and therapeutic compositions for streptococcus pyogenes
WO2008130394A2 (en) 2006-11-30 2008-10-30 The Regents Of The University Of California Array for detecting microbes
JP2010524454A (en) 2007-04-19 2010-07-22 モレキュラー ディテクション インコーポレーテッド Methods, compositions and kits for detection and analysis of antibiotic resistant bacteria
US7811764B2 (en) * 2007-08-14 2010-10-12 University Of Rochester Hybridization-based biosensor containing hairpin probes and use thereof
NZ584793A (en) * 2007-10-26 2012-05-25 Academisch Ziekenhuis Leiden Means and methods for counteracting muscle disorders
USRE48468E1 (en) 2007-10-26 2021-03-16 Biomarin Technologies B.V. Means and methods for counteracting muscle disorders
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US20120077684A1 (en) * 2007-12-26 2012-03-29 O'hara Shawn Mark Methods and Compositions Including Diagnostic Kits For The Detection In Samples Of Methicillin-Resistant Staphylococcus Aureus
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US20120165215A1 (en) * 2009-06-26 2012-06-28 The Regents Of The University Of California Methods and systems for phylogenetic analysis
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EP4663746A3 (en) 2010-02-01 2026-04-15 Ferring Microbiome Inc. Bacteriotherapy for clostridium difficile colitis
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US9725770B2 (en) 2012-03-06 2017-08-08 The Regents Of The University Of California Methods and compositions for identification of source of microbial contamination in a sample
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US9694039B2 (en) 2013-06-05 2017-07-04 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
US9511100B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
PL3307289T3 (en) 2015-06-09 2022-01-17 Rebiotix, Inc. Methods of manufacture of microbiota restoration therapy (mrt) compositions
US10828340B2 (en) 2015-06-09 2020-11-10 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
US10905726B2 (en) 2015-06-09 2021-02-02 Rebiotix, Inc. Microbiota restoration therapy (MRT) compositions and methods of manufacture
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945589B2 (en) 2003-09-15 2015-02-03 Novartis Vaccines And Diagnostics, Srl Immunogenic compositions for Streptococcus agalactiae
US8858957B2 (en) 2007-09-12 2014-10-14 Novartis Ag GAS57 mutant antigens and GAS57 antibodies
US9102741B2 (en) 2007-09-12 2015-08-11 Novartis Ag GAS57 mutant antigens and GAS57 antibodies

Also Published As

Publication number Publication date
US20060160121A1 (en) 2006-07-20
EP1817432A2 (en) 2007-08-15
CA2582137A1 (en) 2007-02-15
AU2005335216A1 (en) 2007-02-15
WO2007018563A2 (en) 2007-02-15

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