WO2007092579A3 - Compositions and methods for capturing and analyzing cross-linked biomolecules - Google Patents

Compositions and methods for capturing and analyzing cross-linked biomolecules Download PDF

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Publication number
WO2007092579A3
WO2007092579A3 PCT/US2007/003416 US2007003416W WO2007092579A3 WO 2007092579 A3 WO2007092579 A3 WO 2007092579A3 US 2007003416 W US2007003416 W US 2007003416W WO 2007092579 A3 WO2007092579 A3 WO 2007092579A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
methods
capturing
analyzing cross
linked biomolecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/003416
Other languages
French (fr)
Other versions
WO2007092579A2 (en
WO2007092579A9 (en
Inventor
Danette Hartzell
Marjeta Urh
Keith V Wood
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Promega Corp
Original Assignee
Promega Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Promega Corp filed Critical Promega Corp
Priority to EP07763411A priority Critical patent/EP1989548A2/en
Publication of WO2007092579A2 publication Critical patent/WO2007092579A2/en
Publication of WO2007092579A9 publication Critical patent/WO2007092579A9/en
Publication of WO2007092579A3 publication Critical patent/WO2007092579A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Methods, compositions and kits to capture cross-linked protein complexes to a support matrix in a stable, covalent bridge of attachment are provided.
PCT/US2007/003416 2006-02-08 2007-02-08 Compositions and methods for capturing and analyzing cross-linked biomolecules Ceased WO2007092579A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07763411A EP1989548A2 (en) 2006-02-08 2007-02-08 Compositions and methods for capturing and analyzing cross-linked biomolecules

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77155806P 2006-02-08 2006-02-08
US60/771,558 2006-02-08

Publications (3)

Publication Number Publication Date
WO2007092579A2 WO2007092579A2 (en) 2007-08-16
WO2007092579A9 WO2007092579A9 (en) 2007-10-04
WO2007092579A3 true WO2007092579A3 (en) 2007-11-15

Family

ID=38185509

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/003416 Ceased WO2007092579A2 (en) 2006-02-08 2007-02-08 Compositions and methods for capturing and analyzing cross-linked biomolecules

Country Status (3)

Country Link
US (1) US20070224620A1 (en)
EP (1) EP1989548A2 (en)
WO (1) WO2007092579A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8168405B2 (en) 2004-07-30 2012-05-01 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor
US8202700B2 (en) 2003-01-31 2012-06-19 Promega Corporation Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2341134B1 (en) 2003-01-31 2014-08-27 Promega Corporation Covalent tethering of functional groups to proteins
US20070087400A1 (en) * 2004-07-30 2007-04-19 Aldis Darzins Covalent tethering of functional groups to proteins and substrates therefor
EP2087107A2 (en) 2006-10-30 2009-08-12 Promega Corporation Mutant hydrolase proteins with enhanced kinetics and functional expression
DK2220107T3 (en) * 2007-11-12 2017-02-13 Chreto Aps Double affinity polypeptide for purification
WO2012112690A2 (en) * 2011-02-16 2012-08-23 Fabius Biotechnology Targeting of therapeutic drugs and diagnostic agents employing collagen binding domains
WO2012154858A1 (en) * 2011-05-09 2012-11-15 Whitehead Institute For Biomedical Research Chaperone interaction assays and uses thereof
US9726671B2 (en) * 2011-08-01 2017-08-08 Biologistics Llc Method of discerning substitution of carbohydrate esters
AU2013359160B2 (en) * 2012-12-12 2018-11-15 Promega Corporation Compositions and methods for capture of cellular targets of bioactive agents
US10168323B2 (en) 2013-03-15 2019-01-01 Promega Corporation Compositions and methods for capture of cellular targets of bioactive agents
EP2969435B1 (en) 2013-03-15 2021-11-03 Promega Corporation Substrates for covalent tethering of proteins to functional groups or solid surfaces
US10683534B2 (en) * 2015-01-27 2020-06-16 BioSpyder Technologies, Inc. Ligation assays in liquid phase
JP6876002B2 (en) * 2015-06-05 2021-05-26 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ Cell-permeable, cell-compatible, and cleaveable linker for covalently anchoring functional elements
CN112778426B (en) * 2021-01-06 2023-12-12 深圳伯生生物传感技术有限公司 Accurate antibody nucleic acid directional connection method
CN119666793B (en) * 2023-09-19 2026-04-28 中国科学院大连化学物理研究所 Detection and/or screening methods for target protein expression cell lines based on fluorescence indicators

Citations (3)

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US5476770A (en) * 1993-01-28 1995-12-19 Commissariat A L'energie Atomique Immunometric determination of an antigen or hapten
US20050095651A1 (en) * 2003-08-12 2005-05-05 The Regents Of The University Of California Photoswitchable method for the ordered attachment of proteins to surfaces
US20050272114A1 (en) * 2003-01-31 2005-12-08 Aldis Darzins Substrates for covalent tethering to proteins

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US3131122A (en) * 1961-04-14 1964-04-28 Boehringer Sohn Ingelheim Method of producing analgesia with n-substituted-4-phenyl-4-carbalkoxypiperidines
US4574079A (en) * 1983-05-27 1986-03-04 Gavras Haralambos P Radiolabeled angiotensin converting enzyme inhibitors for radiolabeling mammalian organ sites
EP0258898B1 (en) * 1986-09-04 1992-04-22 Idemitsu Kosan Company Limited Liquid-crystalline polymer
SE8900130L (en) * 1989-01-16 1990-07-17 Klaus Mosbach THE CONCEPT THAT USING MANUFACTURED ARTIFICIAL ANTIBODIES BY MOLECULE IMPRESSION METHOD BY IMPRINTING ANY ANTIGEN AND BY MANUFACTUREING ARTIFIED ENTYZYMES BY IMPRINTING
US5071469A (en) * 1989-04-21 1991-12-10 E. I. Du Pont De Nemours And Company Herbicidal benzylsulfonamides
US5498694A (en) * 1989-05-25 1996-03-12 La Jolla Cancer Research Foundation Peptides of the cytoplasmic domain of integrin
US5128247A (en) * 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
US5099020A (en) * 1989-11-27 1992-03-24 Abbott Laboratories Barbiturate assay compositions and methods
US5372944A (en) * 1993-10-14 1994-12-13 The Dow Chemical Company Method for conversion of halogenated hydrocarbons to halohydrins
JP3583489B2 (en) * 1994-12-22 2004-11-04 日清紡績株式会社 Carbodiimide derivative
US5945526A (en) * 1996-05-03 1999-08-31 Perkin-Elmer Corporation Energy transfer dyes with enhanced fluorescence
US6416733B1 (en) * 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
US6333154B1 (en) * 1997-12-04 2001-12-25 Institut Pasteur Bacterial multi-hybrid system and applications thereof
AU2594301A (en) * 1999-12-23 2001-07-03 Maxygen, Inc. Alteration of hydrolase genes and screening of the resulting libraries for the ability to catalyze specific reactions
FR2804116B1 (en) * 2000-01-20 2002-08-23 Centre Nat Rech Scient ORGANOSILICATED COMPOUNDS, THEIR PREPARATION PROCESS AND THEIR USES
JP2005502310A (en) * 2000-12-01 2005-01-27 ディヴァーサ コーポレイション Hydrolase enzymes and applications in kinetic resolution
US6800453B2 (en) * 2001-01-23 2004-10-05 President And Fellows Of Harvard College Nucleic-acid programmable protein arrays
US20040152880A1 (en) * 2002-11-22 2004-08-05 Carnegie Mellon University Compositions and methods for the reversible capture of biomolecules
EP2341134B1 (en) * 2003-01-31 2014-08-27 Promega Corporation Covalent tethering of functional groups to proteins
US20070087400A1 (en) * 2004-07-30 2007-04-19 Aldis Darzins Covalent tethering of functional groups to proteins and substrates therefor
US7425436B2 (en) * 2004-07-30 2008-09-16 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476770A (en) * 1993-01-28 1995-12-19 Commissariat A L'energie Atomique Immunometric determination of an antigen or hapten
US20050272114A1 (en) * 2003-01-31 2005-12-08 Aldis Darzins Substrates for covalent tethering to proteins
US20050095651A1 (en) * 2003-08-12 2005-05-05 The Regents Of The University Of California Photoswitchable method for the ordered attachment of proteins to surfaces

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
HODNELAND CHRISTIAN D ET AL: "Selective immobilization of proteins to self-assembled monolayers presenting active site-directed capture ligands", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 99, no. 8, 16 April 2002 (2002-04-16), pages 5048 - 5052, XP002252376, ISSN: 0027-8424 *
KWON Y ET AL: "ANTIBODY ARRAYS PREPARED BY CUTINASE-MEDIATED IMMOBILIZATION ON SELF-ASSEMBLED MONOLAYERS", ANALYTICAL CHEMISTRY, AMERICAN CHEMICAL SOCIETY. COLUMBUS, US, vol. 76, no. 19, 1 October 2004 (2004-10-01), pages 5713 - 5720, XP001209665, ISSN: 0003-2700 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8202700B2 (en) 2003-01-31 2012-06-19 Promega Corporation Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule
US8779221B2 (en) 2003-01-31 2014-07-15 Promega Corporation Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule
US10604745B2 (en) 2003-01-31 2020-03-31 Promega Corporation Method of immobilizing a protein or molecule via a mutant dehalogenase that is bound to an immobilized dehalogenase substrate and linked directly or indirectly to the protein or molecule
US8168405B2 (en) 2004-07-30 2012-05-01 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor
US8466269B2 (en) 2004-07-30 2013-06-18 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor
US8742086B2 (en) 2004-07-30 2014-06-03 Promega Corporation Polynucleotide encoding a mutant dehalogenase to allow tethering to functional groups and substrates
US9416353B2 (en) 2004-07-30 2016-08-16 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor
US10101332B2 (en) 2004-07-30 2018-10-16 Promega Corporation Covalent tethering of functional groups to proteins and substrates therefor

Also Published As

Publication number Publication date
WO2007092579A2 (en) 2007-08-16
US20070224620A1 (en) 2007-09-27
WO2007092579A9 (en) 2007-10-04
EP1989548A2 (en) 2008-11-12

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