WO2007102929A3 - Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo - Google Patents

Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo Download PDF

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Publication number
WO2007102929A3
WO2007102929A3 PCT/US2006/062754 US2006062754W WO2007102929A3 WO 2007102929 A3 WO2007102929 A3 WO 2007102929A3 US 2006062754 W US2006062754 W US 2006062754W WO 2007102929 A3 WO2007102929 A3 WO 2007102929A3
Authority
WO
WIPO (PCT)
Prior art keywords
hydrophilic
cross
synthesis
hollow spheres
cargo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2006/062754
Other languages
French (fr)
Other versions
WO2007102929A2 (en
Inventor
Steven Menchen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems Inc
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Priority to CA002635896A priority Critical patent/CA2635896A1/en
Priority to JP2008548874A priority patent/JP2009522091A/en
Priority to EP06850374A priority patent/EP1979084A2/en
Publication of WO2007102929A2 publication Critical patent/WO2007102929A2/en
Publication of WO2007102929A3 publication Critical patent/WO2007102929A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02Making microcapsules or microballoons
    • B01J13/06Making microcapsules or microballoons by phase separation
    • B01J13/14Polymerisation; cross-linking
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/32Polymerisation in water-in-oil emulsions
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F293/00Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
    • C08F293/005Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule using free radical "living" or "controlled" polymerisation, e.g. using a complexing agent
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F4/00Polymerisation catalysts
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/003Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L53/00Compositions of block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Polyethers (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)

Abstract

Cross-linked hydrophilic nanocapsules and various compositions and methods for their preparation and use are provided.
PCT/US2006/062754 2005-12-30 2006-12-29 Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo Ceased WO2007102929A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002635896A CA2635896A1 (en) 2005-12-30 2006-12-29 Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo
JP2008548874A JP2009522091A (en) 2005-12-30 2006-12-29 Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo
EP06850374A EP1979084A2 (en) 2005-12-30 2006-12-29 Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75567605P 2005-12-30 2005-12-30
US60/755,676 2005-12-30

Publications (2)

Publication Number Publication Date
WO2007102929A2 WO2007102929A2 (en) 2007-09-13
WO2007102929A3 true WO2007102929A3 (en) 2008-04-03

Family

ID=38475319

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/062754 Ceased WO2007102929A2 (en) 2005-12-30 2006-12-29 Synthesis and use of cross-linked hydrophilic hollow spheres for encapsulating hydrophilic cargo

Country Status (6)

Country Link
US (2) US20070166697A1 (en)
EP (1) EP1979084A2 (en)
JP (1) JP2009522091A (en)
CN (1) CN101394925A (en)
CA (1) CA2635896A1 (en)
WO (1) WO2007102929A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009035847A1 (en) * 2007-09-14 2009-03-19 Siemens Heathcare Diagnostics Inc. Apparatus and methods for encapsulation of in vitro diagnostic reagents
CN101362069B (en) * 2008-10-08 2011-06-01 中国科学院过程工程研究所 A kind of hollow porous microcapsule and preparation method thereof
JPWO2012105485A1 (en) * 2011-01-31 2014-07-03 マルホ株式会社 Dermal composition containing polymer reverse micelle and method for producing the same
KR101269075B1 (en) 2011-08-24 2013-05-29 주식회사 제네웰 Hydrophobic valuable compounds encapsulated core-crosslinked amphiphilic polymer nano-capsules prepared using nonionic amphiphilic reactive precursors and their preparation method
CN102766228B (en) * 2012-07-13 2014-06-18 北京科技大学 Preparation method and application of polymeric micelle with triple responsiveness
ES2480343B1 (en) * 2013-01-25 2015-05-20 Ecopol Tech, S.L. Process for the manufacture of a corresponding microencapsulated and reactive amphiphilic compound, microencapsulated and composition
US10809250B2 (en) * 2015-08-25 2020-10-20 Bio-Rad Laboratories, Inc. Digital immunoassay

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1220707C (en) * 1999-09-01 2005-09-28 罗狄亚化学公司 Gelled aqueous composition comprising a block copolymer comprising at least one water-soluble block and one hydrophobic block
US6503975B1 (en) * 2000-03-29 2003-01-07 E. I Du Pont De Nemours And Company Surfactant free aqueous emulsions
US6649138B2 (en) * 2000-10-13 2003-11-18 Quantum Dot Corporation Surface-modified semiconductive and metallic nanoparticles having enhanced dispersibility in aqueous media
DE60307371T2 (en) * 2002-06-14 2007-08-02 Canon K.K. Particle composition, recording method and recording apparatus using the particle composition

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
GERARD RIESS: "Micellization of block copolymers", PROG. POLYM. SCI., vol. 28, no. 7, July 2003 (2003-07-01), pages 1107 - 1170, XP002465087 *
HAIYONG HUANG, EDWARD E. REMSEN, KAREN L. WOOLEY: "Amphiphilic core-shell nanospheres obtained by intramicellar shell crosslinking of polymer micelles with poly(ethylene oxide) linkers", CHEM. COMMUN., 1998, pages 1415 - 1416, XP002465089 *
HYUN M. JUNG, KRISTIN E. PRICE, D. TYLER MCQUADE: "Synthesis and Characterization of Cross-Linked Reverse Micelles", J. AM. CHEM. SOC., vol. 125, no. 18, 9 April 2003 (2003-04-09), pages 5351 - 5355, XP002465088 *
V. BÜTÜN, A.B. LOWE, N.C. BILLINGHAM, S.P. ARMES: "Synthesis of Zwitterionic Shell Cross-Linked Micelles", J. AM. CHEM. SOC., vol. 121, no. 17, 1999, pages 4288 - 4289, XP002465090 *

Also Published As

Publication number Publication date
US20110207234A1 (en) 2011-08-25
JP2009522091A (en) 2009-06-11
EP1979084A2 (en) 2008-10-15
US20070166697A1 (en) 2007-07-19
WO2007102929A2 (en) 2007-09-13
CN101394925A (en) 2009-03-25
CA2635896A1 (en) 2007-09-13

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