WO2007103585A3 - Ventilator assist system and method to improve respiratory function - Google Patents

Ventilator assist system and method to improve respiratory function Download PDF

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Publication number
WO2007103585A3
WO2007103585A3 PCT/US2007/006135 US2007006135W WO2007103585A3 WO 2007103585 A3 WO2007103585 A3 WO 2007103585A3 US 2007006135 W US2007006135 W US 2007006135W WO 2007103585 A3 WO2007103585 A3 WO 2007103585A3
Authority
WO
WIPO (PCT)
Prior art keywords
lung
diaphragm
respiratory function
specific
hemidiaphragm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/006135
Other languages
French (fr)
Other versions
WO2007103585A2 (en
Inventor
Anthony R Ignagni
Raymond P Onders
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synapse Biomedical Inc
Original Assignee
Synapse Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synapse Biomedical Inc filed Critical Synapse Biomedical Inc
Priority to EP07752811A priority Critical patent/EP1996284A2/en
Publication of WO2007103585A2 publication Critical patent/WO2007103585A2/en
Publication of WO2007103585A3 publication Critical patent/WO2007103585A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3601—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of respiratory organs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0551—Spinal or peripheral nerve electrodes

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physiology (AREA)
  • Pulmonology (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Systems and methods are provided to improve respiratory function. Systems include an external electrical stimulator coupled to electrodes that stimulates diaphragm contraction and may optionally include a positive pressure mechanical ventilator. The system further includes an electrode suitable for temporary implantation. Electrical stimulation is provided to specific portions of the diaphragm, such as one hemidiaphragm preferentially over another. By preferentially contracting one hemidiaphragm, a specific portion of a lung may be expanded such as a posterior portion. By the provision of the negative intrathoracic pressure from diaphragm contraction, greater expansion of specific portion of lung is achieved in relationship to air pressure within the lung. Supplementation of stimulated diaphragm contraction with positive pressure driven air flow from a PPMV directs the air flow to specific portions of the lung. Such portion may include a posterior portion of a lung, and may cause a clearing of atelectasis in that portion.
PCT/US2007/006135 2006-03-09 2007-03-09 Ventilator assist system and method to improve respiratory function Ceased WO2007103585A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07752811A EP1996284A2 (en) 2006-03-09 2007-03-09 Ventilatory assist system and method to improve respiratory function

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US76720106P 2006-03-09 2006-03-09
US60/767,201 2006-03-09
US86156806P 2006-11-28 2006-11-28
US60/861,568 2006-11-28
US87226506P 2006-12-01 2006-12-01
US60/872,265 2006-12-01

Publications (2)

Publication Number Publication Date
WO2007103585A2 WO2007103585A2 (en) 2007-09-13
WO2007103585A3 true WO2007103585A3 (en) 2008-01-03

Family

ID=38475618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/006135 Ceased WO2007103585A2 (en) 2006-03-09 2007-03-09 Ventilator assist system and method to improve respiratory function

Country Status (3)

Country Link
US (2) US8676323B2 (en)
EP (1) EP1996284A2 (en)
WO (1) WO2007103585A2 (en)

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US20080125828A1 (en) 2008-05-29
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