WO2007110765A3 - Processes for the preparation of octreotide - Google Patents

Processes for the preparation of octreotide Download PDF

Info

Publication number
WO2007110765A3
WO2007110765A3 PCT/IB2007/000800 IB2007000800W WO2007110765A3 WO 2007110765 A3 WO2007110765 A3 WO 2007110765A3 IB 2007000800 W IB2007000800 W IB 2007000800W WO 2007110765 A3 WO2007110765 A3 WO 2007110765A3
Authority
WO
WIPO (PCT)
Prior art keywords
octreotide
processes
preparation
pharmaceutically acceptable
acceptable salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2007/000800
Other languages
French (fr)
Other versions
WO2007110765A2 (en
Inventor
Kumar Kamlesh Laxmi Singh
Siddiqui Mohammed Jaweed Mukarram
Deshpande Amol Ashok
Roy Anupam Badal Chandra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Ltd
Original Assignee
Wockhardt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Ltd filed Critical Wockhardt Ltd
Priority to EP07734124A priority Critical patent/EP2013226A2/en
Publication of WO2007110765A2 publication Critical patent/WO2007110765A2/en
Anticipated expiration legal-status Critical
Publication of WO2007110765A3 publication Critical patent/WO2007110765A3/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The invention relates to processes for the preparation of pure octreotide or pharmaceutically acceptable salts thereof. The invention also relates to an amorphous form of octreotide and processes for the preparation of amorphous form of octreotide or pharmaceutically acceptable salts thereof. The invention also relates to pharmaceutical compositions that include the pure octreotide or the amorphous octreotide or pharmaceutically acceptable salts thereof.
PCT/IB2007/000800 2006-03-28 2007-03-28 Processes for the preparation of octreotide Ceased WO2007110765A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07734124A EP2013226A2 (en) 2006-03-28 2007-03-28 Processes for the preparation of octreotide

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
IN457/MUM/2006 2006-03-28
IN454MU2006 2006-03-28
IN455MU2006 2006-03-28
IN456/MUM/2006 2006-03-28
IN455/MUM/2006 2006-03-28
IN457MU2006 2006-03-28
IN454/MUM/2006 2006-03-28
IN456MU2006 2006-03-28
IN1372/MUM/2006 2006-08-31
IN1382/MUM/2006 2006-08-31
IN1382MU2006 2006-08-31
IN1372MU2006 2006-08-31

Publications (2)

Publication Number Publication Date
WO2007110765A2 WO2007110765A2 (en) 2007-10-04
WO2007110765A3 true WO2007110765A3 (en) 2009-04-16

Family

ID=38541506

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2007/000800 Ceased WO2007110765A2 (en) 2006-03-28 2007-03-28 Processes for the preparation of octreotide

Country Status (2)

Country Link
EP (1) EP2013226A2 (en)
WO (1) WO2007110765A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2435780C1 (en) * 2010-07-08 2011-12-10 Закрытое Акционерное Общество "Фарм-Синтез" Method for producing cyclic peptide-octreotide
RU2441018C1 (en) * 2010-09-28 2012-01-27 Закрытое Акционерное Общество "Фарм-Синтез" Method of chromatographic purification of octreotide
US20140296144A1 (en) 2011-09-30 2014-10-02 Mylan Laboratories, Ltd. Process for the preparation of octreotide acetate
WO2013132505A1 (en) 2012-03-09 2013-09-12 Natco Pharma Limited Improved process for preparation of octreotide by solution phase peptide synthesis
CN104513293A (en) * 2013-09-26 2015-04-15 深圳信立泰药业股份有限公司 Polypeptide vaccine salt, preparation method thereof, and medicinal product containing salt
WO2017175107A1 (en) * 2016-04-04 2017-10-12 Emcure Pharmaceuticals Limited Process for preparation of octreotide acetate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395403A (en) * 1979-11-27 1983-07-26 Sandoz Ltd. Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
US6987167B2 (en) * 2002-05-22 2006-01-17 Wockhardt Limited Process for production of the somatostatin analog, octreotide

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4395403A (en) * 1979-11-27 1983-07-26 Sandoz Ltd. Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
US6987167B2 (en) * 2002-05-22 2006-01-17 Wockhardt Limited Process for production of the somatostatin analog, octreotide

Also Published As

Publication number Publication date
EP2013226A2 (en) 2009-01-14
WO2007110765A2 (en) 2007-10-04

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