WO2007113566A3 - Raman analysis - Google Patents

Raman analysis Download PDF

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Publication number
WO2007113566A3
WO2007113566A3 PCT/GB2007/001249 GB2007001249W WO2007113566A3 WO 2007113566 A3 WO2007113566 A3 WO 2007113566A3 GB 2007001249 W GB2007001249 W GB 2007001249W WO 2007113566 A3 WO2007113566 A3 WO 2007113566A3
Authority
WO
WIPO (PCT)
Prior art keywords
raman analysis
turbid
elsewhere
tablets
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2007/001249
Other languages
French (fr)
Other versions
WO2007113566A2 (en
Inventor
Pavel Matousek
Anthony William Parker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science and Technology Facilities Council
Original Assignee
Science and Technology Facilities Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36539406&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2007113566(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Science and Technology Facilities Council filed Critical Science and Technology Facilities Council
Priority to EP18209601.6A priority Critical patent/EP3477285B1/en
Priority to CA002647730A priority patent/CA2647730A1/en
Priority to US12/083,073 priority patent/US8085396B2/en
Priority to AU2007232350A priority patent/AU2007232350A1/en
Priority to JP2009503651A priority patent/JP2009536317A/en
Priority to EP07732297.2A priority patent/EP2002243B1/en
Publication of WO2007113566A2 publication Critical patent/WO2007113566A2/en
Publication of WO2007113566A3 publication Critical patent/WO2007113566A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/417—Evaluating particular organs or parts of the immune or lymphatic systems the bone marrow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/22—Fuels; Explosives
    • G—PHYSICS
    • G07—CHECKING-DEVICES
    • G07D—HANDLING OF COINS OR VALUABLE PAPERS, e.g. TESTING, SORTING BY DENOMINATIONS, COUNTING, DISPENSING, CHANGING OR DEPOSITING
    • G07D7/00—Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency
    • G07D7/06—Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using wave or particle radiation
    • G07D7/12—Visible light, infrared or ultraviolet radiation
    • G07D7/1205—Testing spectral properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/656—Raman microprobe

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Credit Cards Or The Like (AREA)
  • Optical Measuring Cells (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

Properties of turbid or scattering samples are determined using Raman spectroscopy with probe light delivered to and subsequently collected from the sample using a transmission geometry. The technique may be applied to pharmaceutical products such as tablets, diagnostic tests such as lateral flow diagnostic strips, and elsewhere.
PCT/GB2007/001249 2006-04-05 2007-04-05 Raman analysis Ceased WO2007113566A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP18209601.6A EP3477285B1 (en) 2006-04-05 2007-04-05 Raman analysis
CA002647730A CA2647730A1 (en) 2006-04-05 2007-04-05 Raman analysis
US12/083,073 US8085396B2 (en) 2006-04-05 2007-04-05 Raman analysis
AU2007232350A AU2007232350A1 (en) 2006-04-05 2007-04-05 Raman analysis
JP2009503651A JP2009536317A (en) 2006-04-05 2007-04-05 Raman analysis
EP07732297.2A EP2002243B1 (en) 2006-04-05 2007-04-05 Raman analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0606891.0A GB0606891D0 (en) 2006-04-05 2006-04-05 Raman Analysis Of Pharmaceutical Tablets
GB0606891.0 2006-04-05

Publications (2)

Publication Number Publication Date
WO2007113566A2 WO2007113566A2 (en) 2007-10-11
WO2007113566A3 true WO2007113566A3 (en) 2007-11-29

Family

ID=36539406

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/GB2007/001289 Ceased WO2007113581A1 (en) 2006-04-05 2007-04-05 Embedded data storage
PCT/GB2007/001249 Ceased WO2007113566A2 (en) 2006-04-05 2007-04-05 Raman analysis

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/GB2007/001289 Ceased WO2007113581A1 (en) 2006-04-05 2007-04-05 Embedded data storage

Country Status (8)

Country Link
US (3) US7911604B2 (en)
EP (4) EP1952129B1 (en)
JP (2) JP2009538156A (en)
CN (2) CN101460091B (en)
AU (2) AU2007232354A1 (en)
CA (2) CA2647730A1 (en)
GB (3) GB0606891D0 (en)
WO (2) WO2007113581A1 (en)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2174560T3 (en) * 1999-08-27 2002-11-01 Degussa OVEN CARBON BLACK, PROCEDURE FOR PREPARATION AND EMPLOYMENT.
GB0606891D0 (en) * 2006-04-05 2006-05-17 Council Cent Lab Res Councils Raman Analysis Of Pharmaceutical Tablets
US8325337B2 (en) * 2007-07-13 2012-12-04 Purdue Research Foundation Time resolved raman spectroscopy
SE531527C2 (en) * 2007-10-01 2009-05-12 Bioresonator Ab Method and apparatus for unaffected material examination
EP3683218B1 (en) 2007-12-07 2024-09-18 Vertex Pharmaceuticals Incorporated Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid
EP2501288B1 (en) 2009-11-19 2016-12-21 Modulated Imaging Inc. Method and apparatus for analysis of turbid media via single-element detection using structured illumination
US20120092663A1 (en) * 2010-10-14 2012-04-19 Kull Linda S Transmission raman spectroscopy analysis of seed composition
DE102011002181A1 (en) * 2011-04-19 2012-10-25 Bundesdruckerei Gmbh Method and device for checking security features in security documents
AU2012350656B2 (en) * 2011-12-16 2015-04-30 Glaxo Group Limited Apparatus for testing samples using Raman radiation
NZ727015A (en) 2012-01-25 2017-12-22 Vertex Pharma Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
WO2013124164A1 (en) * 2012-02-24 2013-08-29 Paul Scherrer Institut A system for non-invasively classification of different types of micro-calcifications in human tissue
CA2889489C (en) 2012-11-07 2021-05-11 David Cuccia Efficient modulated imaging
CN105358946B (en) * 2013-02-14 2017-07-14 曾海山 Optical reference for the calibration of spectral measurement system
US9983136B2 (en) 2013-05-27 2018-05-29 Indian Institute Of Science Method and an apparatus for obtaining sample specific signatures
US9606062B2 (en) * 2013-05-27 2017-03-28 Indian Institute Of Science Method and a system for detection of hazardous chemicals in a non-metallic container
KR20150010392A (en) * 2013-07-19 2015-01-28 케이맥(주) Inspection method and apparatus of crystallized silicon
US20150022802A1 (en) * 2013-07-22 2015-01-22 Frederick Harold LONG Spectroscopy detection system and method for material identification
AU2014349010C1 (en) * 2013-11-12 2020-08-06 Vertex Pharmaceuticals Incorporated Process of preparing pharmaceutical compositions for the treatment of CFTR mediated diseases
CN103743717B (en) * 2013-12-03 2015-09-23 中国工程物理研究院化工材料研究所 Explosive CL-20 crystal formation quantitative test raman signatures area determination method
CN104749158B (en) * 2013-12-27 2020-12-11 同方威视技术股份有限公司 Jewelry and jade identification method and device
US9295420B2 (en) 2014-01-29 2016-03-29 Hong Kong Applied Science and Technology Research Institute Company Limited Transmission-reflectance swappable Raman probe for physiological detections
US10436716B2 (en) * 2014-09-24 2019-10-08 Smiths Detection, Inc. Ubiquitous transmissive raman spectroscopy for stand-off detection
US10072984B2 (en) 2014-10-02 2018-09-11 Mks Technology, Inc. Spectrometer
GB201503911D0 (en) 2015-03-09 2015-04-22 Renishaw Plc Transmission raman spectroscopy
CN104730060A (en) * 2015-03-20 2015-06-24 扬州大学 Method for controllably decreasing and rapidly detecting in-vitro simple simulation bone density
US10288814B2 (en) 2015-03-25 2019-05-14 Board Of Regents Of The University Of Texas System Variable spatial offset fiber optic probe for optical spectography and imaging
GB201511574D0 (en) 2015-07-01 2015-08-12 Stfc Science & Technology Clinical thermometer
WO2017066399A1 (en) * 2015-10-15 2017-04-20 The Usa, As Represented By The Secretary Of The Navy Trace-gas raman spectroscopy in functionalized waveguides
US10365229B2 (en) 2015-12-31 2019-07-30 Kaiser Optical Systems, Inc. Real-time characterization of pharmaceutical tablet coatings using Raman spectroscopy
US11547365B2 (en) * 2016-04-13 2023-01-10 Koninklijke Philips N.V. System and method for skin detection of a human subject
US11092494B1 (en) 2016-05-31 2021-08-17 MKS Technology Spectrometer
GB201618260D0 (en) 2016-10-28 2016-12-14 Science And Tech Facilities Council The Detection of pH
US10119916B2 (en) * 2016-11-11 2018-11-06 B&W Tek Llc Light delivery and collection device for measuring Raman scattering of a sample
US10119917B2 (en) 2016-11-11 2018-11-06 B & W Tek LLC Apparatus and method for bidirectional Raman spectroscopy
WO2018134980A1 (en) 2017-01-20 2018-07-26 オリンパス株式会社 Cartilage tissue analysis device
CN110914675A (en) 2017-04-11 2020-03-24 瑞艾迪粒子系统有限责任公司 Liquid cell unit for microscope-based image acquisition and raman spectroscopy-based material analysis of particle suspensions
CN108398418B (en) * 2018-03-16 2020-12-04 华东理工大学 An internal reference surface-enhanced Raman test paper, preparation method and application
CN108577874B (en) * 2018-05-21 2021-09-17 达影医疗(中山)有限公司 Mammary gland displacement compression device and mammary gland X-ray photography system
JP7075285B2 (en) * 2018-05-29 2022-05-25 株式会社堀場製作所 Calibration curve setting method used for drug analysis
CN109060766A (en) * 2018-09-27 2018-12-21 珠海彩晶光谱科技有限公司 A kind of measurement method and detection device of the concentration in body fluid based on Surface enhanced Raman spectroscopy
GB2572662B (en) 2018-10-05 2020-06-03 Res & Innovation Uk Raman spectrometer
GB2581154B (en) 2019-02-05 2022-09-28 Colvistec Ag Amorphous pharmaceutical compositions
EP3986248B1 (en) 2019-06-19 2025-03-19 Syddansk Universitet Raman computed tomography (raman-ct) system and method
GB201910801D0 (en) 2019-07-29 2019-09-11 Agilent Tech Lda Uk Limited Raman analysis of pharmaceutical dosage forms
DE102019219949A1 (en) * 2019-12-18 2021-06-24 Robert Bosch Gmbh Substrate
GB202004010D0 (en) 2020-03-19 2020-05-06 Res & Innovation Uk Detection of water content in tissue
WO2021195471A1 (en) 2020-03-26 2021-09-30 Innovative Photonic Solutions, Inc. Method for selection of raman excitation wavelengths in multi-source raman probe
GB2594980B (en) 2020-05-14 2025-01-01 Agilent Tech Lda Uk Limited Spectral analysis of a sample
GB2596804A (en) 2020-07-06 2022-01-12 Agilent Tech Lda Uk Limited Raman analysis of pharmaceutical dosage forms
US11304605B2 (en) * 2020-07-20 2022-04-19 123IV, Inc. Self-administered, non-invasive, transcutaneous viral detector
JP7270582B2 (en) * 2020-07-20 2023-05-10 アンリツ株式会社 Spectrometer
US11898959B2 (en) * 2020-12-07 2024-02-13 Harry Owen Solids analysis using Raman spectroscopy
CN114460058B (en) * 2021-02-20 2025-07-22 海南聚能科技创新研究院有限公司 Spectrometer detection device
US12279758B2 (en) * 2021-09-27 2025-04-22 Ai Biomed Corp. Tissue detection systems and methods
US11974726B2 (en) 2021-09-27 2024-05-07 Ai Biomed Corp. Tissue detection systems and methods
GB2615370B (en) 2022-02-08 2025-03-26 Res & Innovation Uk Detection using SERS probes

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714345A (en) * 1984-06-29 1987-12-22 Bernhard Schrader Sample arrangement for spectrometry, method for the measurement of luminescence and scattering and application of the sample arrangement
US5194913A (en) * 1991-03-20 1993-03-16 The United States Of America As Represented By The United States Department Of Energy Fiber-optic apparatus and method for measurement of luminescence and raman scattering
WO1997022872A1 (en) * 1995-12-20 1997-06-26 Astra Aktiebolag Method and device for spectrometry
US6289230B1 (en) * 1998-07-07 2001-09-11 Lightouch Medical, Inc. Tissue modulation process for quantitative noninvasive in vivo spectroscopic analysis of tissues
US6310686B1 (en) * 1997-07-02 2001-10-30 Spectracode, Inc. Raman probe with spatial filter and semi-confocal lens
US20040063214A1 (en) * 2002-09-30 2004-04-01 Berlin Andrew Arthur Spectroscopic analysis system and method
WO2004031749A2 (en) * 2002-09-30 2004-04-15 Intel Corporation Spectroscopic analysis system and method
EP1533607A2 (en) * 1996-06-13 2005-05-25 Ann E. Grow Method for identifying and monitoring analytes by Raman spectrometry

Family Cites Families (106)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3442591A (en) * 1965-03-06 1969-05-06 Hitachi Ltd Apparatus for measuring the raman effect of samples of infinitesimal quantities
US3516744A (en) 1966-05-20 1970-06-23 Perkin Elmer Corp Sampling arrangement for laser-raman systems
US3770350A (en) * 1972-07-24 1973-11-06 Bell Telephone Labor Inc Method utilizing an optical fiber raman cell
US3909132A (en) 1974-06-11 1975-09-30 Allied Chem Spectroscopic temperature measurement
JPS6058820B2 (en) 1979-07-31 1985-12-21 工業技術院長 Surface analysis method for transparent materials
US4645340A (en) * 1983-06-01 1987-02-24 Boston University Optically reflective sphere for efficient collection of Raman scattered light
AU565295B2 (en) * 1983-10-13 1987-09-10 Matsushita Electric Industrial Co., Ltd. Fluid deflecting assembly
US4570638A (en) 1983-10-14 1986-02-18 Somanetics Corporation Method and apparatus for spectral transmissibility examination and analysis
US5139025A (en) * 1983-10-14 1992-08-18 Somanetics Corporation Method and apparatus for in vivo optical spectroscopic examination
GB8514992D0 (en) * 1985-06-13 1985-07-17 British Nuclear Fuels Plc Differentiation technique
US4784486A (en) * 1987-10-06 1988-11-15 Albion Instruments Multi-channel molecular gas analysis by laser-activated Raman light scattering
US4945239A (en) * 1989-03-29 1990-07-31 Center For Innovative Technology Early detection of breast cancer using transillumination
GB9002360D0 (en) * 1990-02-02 1990-04-04 De La Rue Co Plc Ink composition and components thereof
GB9009132D0 (en) * 1990-04-24 1990-06-20 Gersan Ets Method and apparatus for examining an object
US5261410A (en) * 1991-02-07 1993-11-16 Alfano Robert R Method for determining if a tissue is a malignant tumor tissue, a benign tumor tissue, or a normal or benign tissue using Raman spectroscopy
EP0573535B1 (en) 1991-02-26 2000-12-27 Massachusetts Institute Of Technology Systems and methods of molecular spectroscopy to provide for the diagnosis of tissue
US5506678A (en) * 1992-02-24 1996-04-09 Hewlett Packard Company System for collecting weakly scattered electromagnetic radiation
JP3271304B2 (en) * 1992-06-30 2002-04-02 株式会社島津製作所 Time-of-flight ion scattering spectrometer
US5371368A (en) 1992-07-23 1994-12-06 Alfano; Robert R. Ultrafast optical imaging of objects in a scattering medium
US5746210A (en) * 1993-02-26 1998-05-05 David A. Benaron Device and method for detection, localization, and characterization of inhomogeneities in turbid media
US5565982A (en) * 1994-05-31 1996-10-15 Recon Exploration Apparatus and method for time resolved spectroscopy
US5818047A (en) 1994-08-20 1998-10-06 Renishaw Plc Detector for explosive substances
JP3295869B2 (en) 1994-09-08 2002-06-24 株式会社ニコン Raman spectroscopy method
US5625458A (en) * 1994-11-10 1997-04-29 Research Foundation Of City College Of New York Method and system for imaging objects in turbid media using diffusive fermat photons
US5660181A (en) * 1994-12-12 1997-08-26 Physical Optics Corporation Hybrid neural network and multiple fiber probe for in-depth 3-D mapping
US5919140A (en) * 1995-02-21 1999-07-06 Massachusetts Institute Of Technology Optical imaging using time gated scattered light
US5615673A (en) * 1995-03-27 1997-04-01 Massachusetts Institute Of Technology Apparatus and methods of raman spectroscopy for analysis of blood gases and analytes
BR9601329A (en) * 1995-04-14 1998-01-13 Fuji Xerox Co Ltd Belt conveyor roll and image forming device
US5999836A (en) * 1995-06-06 1999-12-07 Nelson; Robert S. Enhanced high resolution breast imaging device and method utilizing non-ionizing radiation of narrow spectral bandwidth
US5636633A (en) * 1995-08-09 1997-06-10 Rio Grande Medical Technologies, Inc. Diffuse reflectance monitoring apparatus
US5760399A (en) 1995-10-02 1998-06-02 Foss Nirsystems, Inc. Measurement of transmission spectra of pharmaceutical tablets
JPH09127001A (en) 1995-10-31 1997-05-16 Ajinomoto Co Inc Nondestructive inspection method for sealed material
JPH09184809A (en) 1995-12-30 1997-07-15 Koyo Ozaki Scattering light measuring apparatus
GB9609793D0 (en) * 1996-05-10 1996-07-17 Ciba Geigy Ag Pigment compositions
US5842995A (en) 1996-06-28 1998-12-01 Board Of Regents, The Univerisity Of Texas System Spectroscopic probe for in vivo measurement of raman signals
US5873831A (en) * 1997-03-13 1999-02-23 The University Of Utah Technology Transfer Office Method and system for measurement of macular carotenoid levels
GB2328016B (en) 1997-08-08 2001-04-25 Pfizer Ltd Spectrophotometric analysis
SE9704873D0 (en) 1997-12-23 1997-12-23 Astra Ab Sampling apparatus
SE9802690D0 (en) 1998-08-07 1998-08-07 Astra Ab Mixing apparatus
GB9819732D0 (en) 1998-09-11 1998-11-04 Renishaw Plc Tool conditioning monitoring
WO2000020843A1 (en) 1998-10-07 2000-04-13 Ecole Polytechnique Federale De Lausanne (Epfl) Method and apparatus for measuring locally and superficially the scattering and absorption properties of turbid media
US6352502B1 (en) 1998-12-03 2002-03-05 Lightouch Medical, Inc. Methods for obtaining enhanced spectroscopic information from living tissue, noninvasive assessment of skin condition and detection of skin abnormalities
SE9903423D0 (en) 1999-09-22 1999-09-22 Astra Ab New measuring technique
WO2001052739A1 (en) 2000-01-21 2001-07-26 Flock Stephen T Optical measurements of bone composition
SE0000314D0 (en) * 2000-01-31 2000-01-31 Astrazeneca Ab Apparatus and method of analysis
SE0000522D0 (en) 2000-02-17 2000-02-17 Astrazeneca Ab Mixing apparatus
US6610351B2 (en) * 2000-04-12 2003-08-26 Quantag Systems, Inc. Raman-active taggants and their recognition
AU2001272003A1 (en) 2000-07-13 2002-02-05 Virginia Commonwealth University Use of ultraviolet, near-ultraviolet and near infrared resonance raman spectroscopy and fluorescence spectroscopy for tissue interrogation of shock states, critical illnesses, and other disease states
JP2002085385A (en) 2000-09-21 2002-03-26 Sadako Honda Method and apparatus for measuring blood sugar value
IL138683A0 (en) * 2000-09-25 2001-10-31 Vital Medical Ltd Apparatus and method for monitoring tissue vitality parameters
JP3836430B2 (en) * 2000-10-04 2006-10-25 東京瓦斯株式会社 Non-destructive reading method for isotope labeling
SE0100283D0 (en) 2001-01-31 2001-01-31 Astrazeneca Ab Sampling apparatus
US6925514B1 (en) * 2001-03-30 2005-08-02 Agere Systems Inc. Multi-protocol bus system and method of operation thereof
US6954667B2 (en) * 2001-06-28 2005-10-11 Chemimage Corporation Method for Raman chemical imaging and characterization of calcification in tissue
JP2003010189A (en) 2001-07-04 2003-01-14 Communication Research Laboratory Biological function information imaging device
KR100976784B1 (en) 2001-09-12 2010-08-19 게르잔 에스테블리쉬먼트 Diamond inspection
US6610977B2 (en) * 2001-10-01 2003-08-26 Lockheed Martin Corporation Security system for NBC-safe building
IL161729A0 (en) 2001-11-06 2005-11-20 C I Systems Ltd In-line spectroscopy for process monitoring
US6825928B2 (en) * 2001-12-19 2004-11-30 Wisconsin Alumni Research Foundation Depth-resolved fluorescence instrument
US6975891B2 (en) * 2001-12-21 2005-12-13 Nir Diagnostics Inc. Raman spectroscopic system with integrating cavity
US6873868B2 (en) 2001-12-31 2005-03-29 Infraredx, Inc. Multi-fiber catheter probe arrangement for tissue analysis or treatment
US6654118B2 (en) * 2002-02-04 2003-11-25 Ortho-Mcneil Pharmaceutical, Inc. Method and apparatus for obtaining molecular data from a pharmaceutical specimen
CA2418399A1 (en) * 2002-02-11 2003-08-11 Bayer Healthcare, Llc Non-invasive system for the determination of analytes in body fluids
EP1475037B1 (en) 2002-02-14 2012-09-12 Toshinori Kato Apparatus for evaluating biological function
US6919556B1 (en) * 2002-02-22 2005-07-19 Monocle Technologies, Inc. System and method for monitoring and evaluating solid and semi-solid materials
WO2003073082A1 (en) 2002-02-28 2003-09-04 Erasmus Universiteit Rotterdam Depth selective ph measurement and uv exposure measurement
SE0200782D0 (en) 2002-03-14 2002-03-14 Astrazeneca Ab Method of analyzing a pharmaceutical sample
US7647092B2 (en) 2002-04-05 2010-01-12 Massachusetts Institute Of Technology Systems and methods for spectroscopy of biological tissue
US7197562B2 (en) 2002-04-05 2007-03-27 Infocus Corporation Projector device management system
IL151745A (en) * 2002-09-12 2007-10-31 Uzi Sharon Explosive detection and identification system
CA2501098C (en) * 2002-10-23 2014-04-08 Palomar Medical Technologies, Inc. Phototreatment device for use with coolants and topical substances
EP1567852B1 (en) 2002-12-02 2007-06-06 River Diagnostics B.V. Use of high wavenumber raman spectroscopy for measuring tissue
US6897951B2 (en) * 2003-02-14 2005-05-24 Raman Systems, Inc. Probe assemblies for Raman spectroscopy
JP4136704B2 (en) 2003-02-19 2008-08-20 株式会社島津製作所 Probe for optical measurement device and multichannel optical measurement device using the same
JP2004271220A (en) 2003-03-05 2004-09-30 Toshiba Ceramics Co Ltd Apparatus and method for evaluating quartz glass
EP2301439A1 (en) 2003-03-05 2011-03-30 InfraReDx, Inc. Catheter probe arrangement for tissue analysis by radiant energy delivery and radiant energy collection
JP2004294150A (en) 2003-03-26 2004-10-21 Univ Waseda Spectroscopic analyzer and spectroscopic method
US7110109B2 (en) * 2003-04-18 2006-09-19 Ahura Corporation Raman spectroscopy system and method and specimen holder therefor
WO2004097365A2 (en) 2003-04-30 2004-11-11 Mcgill University Method and system for measuring lactate levels in vivo
AU2003284845A1 (en) * 2003-05-15 2004-12-03 Alexei Alexeevich Agibalov Method for forming a database for determining biological agents and chemical substances
US7242469B2 (en) * 2003-05-27 2007-07-10 Opto Trace Technologies, Inc. Applications of Raman scattering probes
RU2269116C2 (en) * 2003-06-18 2006-01-27 Глеб Игоревич Андреев Device for forming database for biologic agents and chemical substances
JP4388318B2 (en) * 2003-06-27 2009-12-24 オリンパス株式会社 Image processing device
US7396650B2 (en) * 2003-06-27 2008-07-08 Commissariat A L'energie Atomique Method for dosing a biological or chemical sample
WO2005004714A1 (en) 2003-07-01 2005-01-20 The Regents Of The University Of Michigan Method and apparatus for diagnosing bone tissue conditions
JP2005070009A (en) 2003-08-28 2005-03-17 Toyota Motor Corp Spectroscopic analyzer
US20060249423A1 (en) 2003-11-28 2006-11-09 Mika Reijonen Method and apparatus to identify and separate medicinal preparations and dosages thereof
US7148963B2 (en) 2003-12-10 2006-12-12 Kaiser Optical Systems Large-collection-area optical probe
US7697576B2 (en) * 2004-05-05 2010-04-13 Chem Image Corporation Cytological analysis by raman spectroscopic imaging
CN1584555A (en) 2004-06-01 2005-02-23 浙江大学 Petroleum products quality rapid measuring instrument based on low-resolution Raman spectra
US7796243B2 (en) 2004-06-09 2010-09-14 National Research Council Of Canada Detection and monitoring of changes in mineralized tissues or calcified deposits by optical coherence tomography and Raman spectroscopy
WO2006005022A2 (en) * 2004-06-30 2006-01-12 Chemimage Corporation Dynamic chemical imaging of biological cells and other subjects
EP1766351A4 (en) * 2004-06-30 2009-12-02 Chemimage Corp MULTIMODAL DANGEROUS AGENT IDENTIFICATION METHOD
WO2006083316A2 (en) * 2004-06-30 2006-08-10 Chemimage Corporation Multipoint method for identifying hazardous agents
US7269245B2 (en) * 2004-07-30 2007-09-11 Bruker Axs, Inc. Combinatorial screening system and X-ray diffraction and Raman spectroscopy
GB0426993D0 (en) 2004-12-09 2005-01-12 Council Cent Lab Res Councils Apparatus for depth-selective raman spectroscopy
WO2006078980A2 (en) * 2005-01-20 2006-07-27 Chemimage Corporation Method for raman computer tomography imaging spectroscopy
JP4595571B2 (en) * 2005-02-04 2010-12-08 セイコーエプソン株式会社 Micro Raman spectroscopy apparatus and micro Raman spectroscopy measurement method
US8452365B2 (en) * 2005-05-25 2013-05-28 Bayer Healthcare Llc Methods of using Raman spectral information in determining analyte concentrations
WO2007040589A1 (en) 2005-09-16 2007-04-12 The Regents Of The University Of Michigan Method and system for measuring sub-surface composition of a sample
WO2007060467A1 (en) 2005-11-25 2007-05-31 The Science And Technology Facilities Council Security screening using raman analysis
GB0606891D0 (en) 2006-04-05 2006-05-17 Council Cent Lab Res Councils Raman Analysis Of Pharmaceutical Tablets
WO2007113570A1 (en) 2006-04-05 2007-10-11 The Science And Technology Facilities Council Raman analysis of tissue
US7603151B2 (en) * 2006-08-22 2009-10-13 Bayer Healthcare Llc Non-invasive methods of using spectral information in determining analyte concentrations
CA2661952A1 (en) 2006-08-22 2008-02-28 Bayer Healthcare Llc Non-invasive methods of using spectral information in determining analyte concentrations
JP4862730B2 (en) * 2007-04-05 2012-01-25 コニカミノルタセンシング株式会社 Pulse wave data analysis method, system, program

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4714345A (en) * 1984-06-29 1987-12-22 Bernhard Schrader Sample arrangement for spectrometry, method for the measurement of luminescence and scattering and application of the sample arrangement
US5194913A (en) * 1991-03-20 1993-03-16 The United States Of America As Represented By The United States Department Of Energy Fiber-optic apparatus and method for measurement of luminescence and raman scattering
WO1997022872A1 (en) * 1995-12-20 1997-06-26 Astra Aktiebolag Method and device for spectrometry
EP1533607A2 (en) * 1996-06-13 2005-05-25 Ann E. Grow Method for identifying and monitoring analytes by Raman spectrometry
US6310686B1 (en) * 1997-07-02 2001-10-30 Spectracode, Inc. Raman probe with spatial filter and semi-confocal lens
US6289230B1 (en) * 1998-07-07 2001-09-11 Lightouch Medical, Inc. Tissue modulation process for quantitative noninvasive in vivo spectroscopic analysis of tissues
US20040063214A1 (en) * 2002-09-30 2004-04-01 Berlin Andrew Arthur Spectroscopic analysis system and method
WO2004031749A2 (en) * 2002-09-30 2004-04-15 Intel Corporation Spectroscopic analysis system and method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BUTTERFIELD D.: "Through-package applications of Raman spectroscopy for nondestructive identification of product", AMERICAN LABORATORY NEWS, November 1999 (1999-11-01), XP002450781 *
MATOUSEK P ET AL: "SUBSURFACE PROBING IN DIFFUSELY SCATTERING MEDIA USING SPATIALLY OFFSET RAMAN SPECTROSCOPY", APPLIED SPECTROSCOPY, THE SOCIETY FOR APPLIED SPECTROSCOPY. BALTIMORE, US, vol. 59, no. 4, April 2005 (2005-04-01), pages 393 - 400, XP008075254, ISSN: 0003-7028 *

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