WO2007114740A3 - Transplant biologique destiné à la thérapie cellulaire à base de cellules souches mésenchymateuses, obtenues à partir de la moelle osseuse - Google Patents

Transplant biologique destiné à la thérapie cellulaire à base de cellules souches mésenchymateuses, obtenues à partir de la moelle osseuse Download PDF

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Publication number
WO2007114740A3
WO2007114740A3 PCT/RU2007/000178 RU2007000178W WO2007114740A3 WO 2007114740 A3 WO2007114740 A3 WO 2007114740A3 RU 2007000178 W RU2007000178 W RU 2007000178W WO 2007114740 A3 WO2007114740 A3 WO 2007114740A3
Authority
WO
WIPO (PCT)
Prior art keywords
biotransplant
bone marrow
stem cells
producing
homogeneous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/RU2007/000178
Other languages
English (en)
French (fr)
Other versions
WO2007114740A2 (en
Inventor
Nikolay Nikolaevich Buhartsev
Svetlana Nikolaevna Vijde
Igor Veniaminovich Galanin
Tatyana Vitaljevna Kisljakova
Peter Vladimirovich Kruglakov
Dmitry Genrihovich Polyntsev
Irina Borisovna Sokolova
Taras Aleksandrovich Skoromets
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TRANS-TECHNOLOGIES Ltd
TRANS TECHNOLOGIES Ltd
Original Assignee
TRANS-TECHNOLOGIES Ltd
TRANS TECHNOLOGIES Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU2006110590/13A external-priority patent/RU2303632C1/ru
Priority claimed from RU2006117609/15A external-priority patent/RU2006117609A/ru
Priority claimed from RU2006117602/15A external-priority patent/RU2303462C1/ru
Application filed by TRANS-TECHNOLOGIES Ltd, TRANS TECHNOLOGIES Ltd filed Critical TRANS-TECHNOLOGIES Ltd
Priority to EP07747891.5A priority Critical patent/EP2009096B8/de
Publication of WO2007114740A2 publication Critical patent/WO2007114740A2/ru
Publication of WO2007114740A3 publication Critical patent/WO2007114740A3/ru
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PCT/RU2007/000178 2006-04-04 2007-04-04 Biotransplant for cellular therapy based on mesenchymal bone marrow stem cells Ceased WO2007114740A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP07747891.5A EP2009096B8 (de) 2006-04-04 2007-04-04 Biotransplantat für die zelltherapie auf der grundlage mesenchymaler knochenmark-stammzellen

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
RU2006110590/13A RU2303632C1 (ru) 2006-04-04 2006-04-04 Способ получения мезенхимальных стволовых клеток из костного мозга млекопитающих и популяция мезенхимальных стволовых клеток, полученная этим способом
RU2006110590 2006-04-04
RU2006117602 2006-05-23
RU2006117609/15A RU2006117609A (ru) 2006-05-23 2006-05-23 Лечение последствий черепно-мозговой травмы и острых нарушений мозгового кровообращения с помощью аутологичных мезенхимальных стволовых клеток
RU2006117602/15A RU2303462C1 (ru) 2006-05-23 2006-05-23 Биотрансплантат и способ лечения задержки психического развития
RU2006117609 2006-05-23

Publications (2)

Publication Number Publication Date
WO2007114740A2 WO2007114740A2 (en) 2007-10-11
WO2007114740A3 true WO2007114740A3 (fr) 2008-01-03

Family

ID=38564099

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/RU2007/000178 Ceased WO2007114740A2 (en) 2006-04-04 2007-04-04 Biotransplant for cellular therapy based on mesenchymal bone marrow stem cells

Country Status (2)

Country Link
EP (1) EP2009096B8 (ru)
WO (1) WO2007114740A2 (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2411010C1 (ru) * 2009-09-21 2011-02-10 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО НижГМА Росздрава) Способ подготовки костных трансплантатов при пластике дефектов костной ткани
EA036374B1 (ru) * 2016-11-17 2020-10-30 Сергей Владимирович Шахрай Способ лечения анальной инконтиненции

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069449A2 (en) * 1999-05-14 2000-11-23 Advanced Tissue Sciences, Inc. Conditioned cell culture medium compositions and methods of use
WO2003070922A1 (en) * 2002-02-19 2003-08-28 Medipost Co., Ltd. Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues
WO2005121317A2 (en) * 2004-04-09 2005-12-22 Teplyashin Alexander S Method for obtaining mesenchymal stem cells
EP1767617A1 (en) * 2005-09-26 2007-03-28 Letizia Mazzini Mesenchymal stem cells isolation and expansion method and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000069449A2 (en) * 1999-05-14 2000-11-23 Advanced Tissue Sciences, Inc. Conditioned cell culture medium compositions and methods of use
WO2003070922A1 (en) * 2002-02-19 2003-08-28 Medipost Co., Ltd. Isolation and culture-expansion methods of mesenchymal stem/progenitor cells from umbilical cord blood, and differentiation method of umbilical cord blood-derived mesenchymal stem/progenitor cells into various mesenchymal tissues
WO2005121317A2 (en) * 2004-04-09 2005-12-22 Teplyashin Alexander S Method for obtaining mesenchymal stem cells
EP1767617A1 (en) * 2005-09-26 2007-03-28 Letizia Mazzini Mesenchymal stem cells isolation and expansion method and uses thereof

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
CHEN X ET AL: "HUMAN BONE MARROW STROMAL CELL CULTURES CONDITIONED BY TRAUMATIC BRAIN TISSUE EXTRACTS: GROWTH FACTOR PRODUCTION", JOURNAL OF NEUROSCIENCE RESEARCH, WILEY-LISS, US, vol. 69, no. 5, 2 August 2002 (2002-08-02), pages 687 - 691, XP009044236, ISSN: 0360-4012 *
JUN FENG JI ET AL: "Interactions of chemokines and chemokine receptors mediate the migration of mesenchymal stem cells to the impaired site in the brain after hypoglossal nerve injury", STEM CELLS, ALPHAMED PRESS, DAYTON, OH, US, vol. 22, no. 3, May 2004 (2004-05-01), pages 415 - 427, XP009055260, ISSN: 1066-5099 *
KAN I ET AL: "Integral therapeutic potential of bone marrow mesenchymal stem cells.", CURRENT DRUG TARGETS FEB 2005, vol. 6, no. 1, February 2005 (2005-02-01), pages 31 - 41, XP002456405, ISSN: 1389-4501 *
PITTENGER M F ET AL: "MULTILINEAGE POTENTIAL OF ADULT HUMAN MESENCHYMAL STEM CELLS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 284, no. 5411, 2 April 1999 (1999-04-02), pages 143 - 147, XP000867221, ISSN: 0036-8075 *
PITTENGER M F; ET AL: "MULTILINEAGE POTENTIAL OF ADULT HUMAN MESENCHYMAL STEM CELLS", SCIENCE, vol. 284, 2 April 1999 (1999-04-02), pages 1 - 7, XP002456406, Retrieved from the Internet <URL:http://www.sciencemag.org/feature/data/983855.dtl> [retrieved on 20071024] *
SOKOLOVA I B ET AL: "Distribution of mesenchymal stem cells in the area of tissue inflammation after transplantation of the cell material via different routes", BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 143, no. 1, 1 January 2007 (2007-01-01), pages 143 - 146, XP019497926, ISSN: 1573-8221 *
SOKOLOVA I B ET AL: "Effect of mesenchymal stem cell transplantation on cognitive functions in rats with ischemic stroke", BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 142, no. 4, 1 October 2006 (2006-10-01), pages 511 - 514, XP019463877, ISSN: 1573-8221 *
STUTE N ET AL: "Autologous serum for isolation and expansion of human mesenchymal stem cells for clinical use", EXPERIMENTAL HEMATOLOGY, NEW YORK, NY, US, vol. 32, no. 12, December 2004 (2004-12-01), pages 1212 - 1225, XP004674871, ISSN: 0301-472X *
WAGNER ET AL: "Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood", EXPERIMENTAL HEMATOLOGY, NEW YORK, NY, US, vol. 33, no. 11, November 2005 (2005-11-01), pages 1402 - 1416, XP005136979, ISSN: 0301-472X *

Also Published As

Publication number Publication date
EP2009096B1 (de) 2016-11-09
WO2007114740A2 (en) 2007-10-11
EP2009096B8 (de) 2017-01-25
EP2009096A2 (de) 2008-12-31

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