WO2007119574A3 - A method for producing an l-amino acid using bacterium of the enterobacteriaceae family with attenuated expression of a gene coding for small rna - Google Patents

A method for producing an l-amino acid using bacterium of the enterobacteriaceae family with attenuated expression of a gene coding for small rna Download PDF

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Publication number
WO2007119574A3
WO2007119574A3 PCT/JP2007/056752 JP2007056752W WO2007119574A3 WO 2007119574 A3 WO2007119574 A3 WO 2007119574A3 JP 2007056752 W JP2007056752 W JP 2007056752W WO 2007119574 A3 WO2007119574 A3 WO 2007119574A3
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WIPO (PCT)
Prior art keywords
bacterium
producing
amino acid
gene coding
enterobacteriaceae family
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Ceased
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PCT/JP2007/056752
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French (fr)
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WO2007119574A2 (en
Inventor
Konstantin Vyacheslavovi Rybak
Aleksandra Yuriev Skorokhodova
Elvira Borisovna Voroshilova
Mikhail Markovich Gusyatiner
Tatyana Viktorovna Leonova
Yury Ivanovich Kozlov
Takuji Ueda
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Ajinomoto Co Inc
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Ajinomoto Co Inc
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Priority to EP07740190A priority Critical patent/EP2004803A2/en
Publication of WO2007119574A2 publication Critical patent/WO2007119574A2/en
Publication of WO2007119574A3 publication Critical patent/WO2007119574A3/en
Priority to US12/212,743 priority patent/US7803584B2/en
Anticipated expiration legal-status Critical
Priority to US12/858,658 priority patent/US8088606B2/en
Priority to US13/307,627 priority patent/US8227214B2/en
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genus Escherichia or Pantoea, which has been modified to attenuate expression of a gene coding for sRNA.
PCT/JP2007/056752 2006-03-23 2007-03-22 A method for producing an l-amino acid using bacterium of the enterobacteriaceae family with attenuated expression of a gene coding for small rna Ceased WO2007119574A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP07740190A EP2004803A2 (en) 2006-03-23 2007-03-22 A method for producing an l-amino acid using bacterium of theenterobacteriaceae family with attenuated expression of a gene coding for small rna
US12/212,743 US7803584B2 (en) 2006-03-23 2008-09-18 Method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
US12/858,658 US8088606B2 (en) 2006-03-23 2010-08-18 Method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA
US13/307,627 US8227214B2 (en) 2006-03-23 2011-11-30 Method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA

Applications Claiming Priority (22)

Application Number Priority Date Filing Date Title
RU2006109062 2006-03-23
RU2006109062 2006-03-23
RU2006109063 2006-03-23
RU2006109063 2006-03-23
RU2006111809 2006-04-11
RU2006111809 2006-04-11
RU2006111808 2006-04-11
RU2006111808 2006-04-11
RU2006115067 2006-05-04
RU2006115068 2006-05-04
RU2006115068 2006-05-04
RU2006115070 2006-05-04
RU2006115070 2006-05-04
RU2006115067 2006-05-04
RU2006119216 2006-06-02
RU2006119216 2006-06-02
RU2006123751 2006-07-04
RU2006123751 2006-07-04
RU2007101437 2007-01-16
RU2007101437 2007-01-16
RU2007101440 2007-01-16
RU2007101440 2007-01-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/212,743 Continuation US7803584B2 (en) 2006-03-23 2008-09-18 Method for producing an L-amino acid using bacterium of the Enterobacteriaceae family with attenuated expression of a gene coding for small RNA

Publications (2)

Publication Number Publication Date
WO2007119574A2 WO2007119574A2 (en) 2007-10-25
WO2007119574A3 true WO2007119574A3 (en) 2008-05-29

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Family Applications (1)

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PCT/JP2007/056752 Ceased WO2007119574A2 (en) 2006-03-23 2007-03-22 A method for producing an l-amino acid using bacterium of the enterobacteriaceae family with attenuated expression of a gene coding for small rna

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Country Link
US (3) US7803584B2 (en)
EP (5) EP2184348B1 (en)
WO (1) WO2007119574A2 (en)

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US11485986B2 (en) 2018-01-09 2022-11-01 Cathay Biotech Inc. Cells and methods for production of lysine and lysine-derived products

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US7915018B2 (en) 2004-10-22 2011-03-29 Ajinomoto Co., Inc. Method for producing L-amino acids using bacteria of the Enterobacteriaceae family
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RU2006145712A (en) * 2006-12-22 2008-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR PRODUCING L-AMINO ACIDS BY THE FERMENTATION METHOD USING BACTERIA HAVING AN INCREASED ABILITY FOR GYLICERINE DISPOSAL
JP2010110217A (en) * 2007-02-22 2010-05-20 Ajinomoto Co Inc L-amino acid-producing microorganism and method for producing l-amino acid
JP2010226956A (en) * 2007-07-23 2010-10-14 Ajinomoto Co Inc Method for producing l-lysine
RU2008105793A (en) * 2008-02-19 2009-08-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR DESIGNING OPERONS CONTAINING TRANSLATION-CONJUGATED GENES, BACTERIA CONTAINING SUCH OPERON, METHOD FOR PRODUCING USEFUL METABOLITIS AND METHOD FOR EXPRESS MONITORING
RU2008148283A (en) * 2008-12-09 2010-06-20 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) METHOD FOR PRODUCING L-ARGININE USING THE BACTERIA OF THE ENTEROBACTERIACEAE FAMILY IN WHICH THE EXPRESSION OF THE ARTI GENE WAS DECREASED
RU2471870C2 (en) 2010-06-03 2013-01-10 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR PRODUCING L-ARGININE AND L-CITRULLINE WITH USE OF BACTERIA OF ENTEROBACTERIACEAE FAMILY WITH ATTENUATED pepA GENE EXPRESSION
RU2501858C2 (en) 2010-07-21 2013-12-20 Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО АГРИ) METHOD FOR OBTAINING L-AMINOACID USING BACTERIUM OF Enterobacteriaceae FAMILY
JP2014036576A (en) * 2010-12-10 2014-02-27 Ajinomoto Co Inc Method for producing l-amino acids
ES2709105T3 (en) * 2012-01-11 2019-04-15 Korea Advanced Inst Sci & Tech RNAs of regulation of synthesis and procedure of preparation of the same
RU2013147882A (en) 2013-10-28 2015-05-10 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") METHOD FOR PRODUCING L-AMINO ACIDS USING BACTERIA OF THE Enterobacteriaceae FAMILY IN WHICH THE PUTRESCIN DEGRADATION WAY IS BROKEN
CN104694535A (en) * 2013-12-09 2015-06-10 江苏命码生物科技有限公司 Non-coding RNA of in-vivo infecting microorganism, parasitic microorganism, symbiotic microorganism, as well as identification and application thereof
KR20210133323A (en) * 2013-12-13 2021-11-05 바스프 에스이 Recombinant microorganism for improved production of fine chemicals
US9616114B1 (en) * 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
US9767554B2 (en) * 2015-02-19 2017-09-19 Sony Corporation Method and system for detection of surgical gauze during anatomical surgery
CA2988415A1 (en) * 2015-06-04 2016-12-08 Basf Se Recombinant microorganism for improved production of fine chemicals
MY189932A (en) 2015-06-12 2022-03-22 Basf Se Recombinant microorganism for improved production of alanine
CN110872595B (en) * 2018-08-31 2024-01-12 华南理工大学 Acid-fast expression cassette and its application in fermentation to produce organic acids

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