WO2007147063A3 - Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample - Google Patents

Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample Download PDF

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Publication number
WO2007147063A3
WO2007147063A3 PCT/US2007/071232 US2007071232W WO2007147063A3 WO 2007147063 A3 WO2007147063 A3 WO 2007147063A3 US 2007071232 W US2007071232 W US 2007071232W WO 2007147063 A3 WO2007147063 A3 WO 2007147063A3
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WIPO (PCT)
Prior art keywords
quantification
detection
methods
nucleic acid
amplification
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Ceased
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PCT/US2007/071232
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French (fr)
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WO2007147063A2 (en
Inventor
Min Seob Lee
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Sequenom Inc
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Sequenom Inc
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Publication date
Application filed by Sequenom Inc filed Critical Sequenom Inc
Priority to EP07798573A priority Critical patent/EP2038426A2/en
Priority to CA002655269A priority patent/CA2655269A1/en
Priority to AU2007260750A priority patent/AU2007260750A1/en
Priority to JP2009515648A priority patent/JP2009540802A/en
Publication of WO2007147063A2 publication Critical patent/WO2007147063A2/en
Anticipated expiration legal-status Critical
Publication of WO2007147063A3 publication Critical patent/WO2007147063A3/en
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Methods and kits for the amplification, detection and quantification of a nucleic acid from a sample are disclosed The methods of the invention may be used in a wide range of applications, including, but not limited to, the detection and quantification of fetal nucleic acid from maternal plasma, the detection and quantification of circulating nucleic acids from neoplasms (malignant or non-malignant), accurate pooling analysis for low frequency alleles, or any other application requinng sensitive quantitative analysis of nucleic acids
PCT/US2007/071232 2006-06-16 2007-06-14 Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample Ceased WO2007147063A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP07798573A EP2038426A2 (en) 2006-06-16 2007-06-14 Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample
CA002655269A CA2655269A1 (en) 2006-06-16 2007-06-14 Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample
AU2007260750A AU2007260750A1 (en) 2006-06-16 2007-06-14 Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample
JP2009515648A JP2009540802A (en) 2006-06-16 2007-06-14 Methods and compositions for amplifying, detecting and quantifying nucleic acids from samples

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80507306P 2006-06-16 2006-06-16
US60/805,073 2006-06-16

Publications (2)

Publication Number Publication Date
WO2007147063A2 WO2007147063A2 (en) 2007-12-21
WO2007147063A3 true WO2007147063A3 (en) 2009-04-02

Family

ID=38832863

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/071232 Ceased WO2007147063A2 (en) 2006-06-16 2007-06-14 Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample

Country Status (7)

Country Link
US (1) US20080096766A1 (en)
EP (1) EP2038426A2 (en)
JP (1) JP2009540802A (en)
CN (1) CN101501251A (en)
AU (1) AU2007260750A1 (en)
CA (1) CA2655269A1 (en)
WO (1) WO2007147063A2 (en)

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