WO2008002951A3 - Chamber apparatus - Google Patents

Chamber apparatus Download PDF

Info

Publication number
WO2008002951A3
WO2008002951A3 PCT/US2007/072172 US2007072172W WO2008002951A3 WO 2008002951 A3 WO2008002951 A3 WO 2008002951A3 US 2007072172 W US2007072172 W US 2007072172W WO 2008002951 A3 WO2008002951 A3 WO 2008002951A3
Authority
WO
WIPO (PCT)
Prior art keywords
substrate
chamber
frame
gasket
integrated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/072172
Other languages
French (fr)
Other versions
WO2008002951A2 (en
Inventor
Solomon R Pena
Kevin M Reinhart
Roberta L Druyor-Sanchez
Noah Lermer
Tamma Kaysser-Kranich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Global Life Sciences Solutions USA LLC
Original Assignee
GE Healthcare Bio Sciences Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GE Healthcare Bio Sciences Corp filed Critical GE Healthcare Bio Sciences Corp
Priority to US12/303,425 priority Critical patent/US20090253582A1/en
Priority to JP2009518524A priority patent/JP2009542222A/en
Priority to EP07812344A priority patent/EP2043785A2/en
Publication of WO2008002951A2 publication Critical patent/WO2008002951A2/en
Publication of WO2008002951A3 publication Critical patent/WO2008002951A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/16—Making multilayered or multicoloured articles
    • B29C45/1676—Making multilayered or multicoloured articles using a soft material and a rigid material, e.g. making articles with a sealing part
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Mechanical Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

This invention provides a system that allows a user to assemble a chamber apparatus (100) that prohibits samples from leaking or mixing with other samples or chamber array wells, when they are inserted into an array well of the chamber apparatus (100). In addition, the chamber frame (101) design allows for easy assembly and disassembly for simplified use and slide substrate (103) scanning on conventional microarray scanners. Chamber apparatus (100) includes a chamber frame (101) with an upper integrated gasket (101a) and a lower integrated gasket (101b), a substrate, and a substrate frame (105) that positions and captures the substrate (103). The lower integrated gasket (101b) provides a single sealing surface between the chamber frame (101) and the substrate (103). The upper integrated gasket (101a) interfaces with a chamber cover (611) forming a compression seal that prevents sample loss due to evaporation during the hybridization process. The chamber frame (101) and substrate frame (105) have integrated features (105a) that allow them to align and fasten to each other by latching or snapping resulting in an optimal clamping force to produce a compression seal between the integrated lower gasket (101b) and the substrate (103).
PCT/US2007/072172 2006-06-29 2007-06-27 Chamber apparatus Ceased WO2008002951A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/303,425 US20090253582A1 (en) 2006-06-29 2007-06-27 Chamber apparatus
JP2009518524A JP2009542222A (en) 2006-06-29 2007-06-27 Chamber device
EP07812344A EP2043785A2 (en) 2006-06-29 2007-06-27 Chamber apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80610806P 2006-06-29 2006-06-29
US60/806,108 2006-06-29

Publications (2)

Publication Number Publication Date
WO2008002951A2 WO2008002951A2 (en) 2008-01-03
WO2008002951A3 true WO2008002951A3 (en) 2008-03-13

Family

ID=38705052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/072172 Ceased WO2008002951A2 (en) 2006-06-29 2007-06-27 Chamber apparatus

Country Status (4)

Country Link
US (1) US20090253582A1 (en)
EP (1) EP2043785A2 (en)
JP (1) JP2009542222A (en)
WO (1) WO2008002951A2 (en)

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AU2011237729B2 (en) 2010-04-05 2014-04-03 Prognosys Biosciences, Inc. Spatially encoded biological assays
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CN104614516B (en) * 2014-01-09 2016-03-30 南京医科大学第一附属医院 Guarantee the microslide couveuse that experimental result is good
CN104597234B (en) * 2014-01-13 2016-03-16 南通大学 The microslide couveuse of rational in infrastructure, detachable, volume adjustable and vaporization prevention
CN103743899B (en) * 2014-01-13 2015-04-15 南通大学 Detachable and adjustable volume slide incubator
CN104614512B (en) * 2014-01-13 2016-04-20 南通大学 The microslide couveuse of detachable, the volume adjustable that experimental result is good and vaporization prevention
USD815752S1 (en) * 2014-11-28 2018-04-17 Randox Laboratories Ltd. Biochip well
CN104568557A (en) * 2014-12-22 2015-04-29 珠海迪尔生物工程有限公司 Clamp for fixing slide
CN120425026A (en) 2015-04-10 2025-08-05 十程基因技术瑞典公司 Spatial differentiation of biological samples and multiplex nucleic acid analysis
USD771834S1 (en) * 2015-04-28 2016-11-15 University Of British Columbia Microfluidic cartridge
USD800336S1 (en) * 2016-07-13 2017-10-17 Precision Nanosystems Inc Microfluidic cartridge
USD800335S1 (en) * 2016-07-13 2017-10-17 Precision Nanosystems Inc. Microfluidic chip
USD812242S1 (en) * 2016-07-13 2018-03-06 Precision Nanosystems Inc Microfluidic cartridge
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USD891635S1 (en) 2018-01-19 2020-07-28 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
JP1614365S (en) 2018-01-19 2018-09-25
USD898940S1 (en) 2018-01-19 2020-10-13 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
JP1619171S (en) 2018-01-19 2018-11-26
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USD901715S1 (en) * 2018-01-19 2020-11-10 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
JP1614369S (en) 2018-01-19 2018-09-25
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USD895142S1 (en) 2018-01-19 2020-09-01 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
JP1619173S (en) 2018-01-19 2018-11-26
USD895832S1 (en) 2018-01-19 2020-09-08 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
JP1614536S (en) 2018-01-19 2018-09-25
USD894421S1 (en) 2018-01-19 2020-08-25 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
USD895835S1 (en) 2018-01-19 2020-09-08 Hamamatsu Photonics K.K. Sample holder for ionized sample analysis
USD883513S1 (en) * 2018-11-02 2020-05-05 Hologic, Inc. Slide rack carrier
US20220290217A1 (en) 2018-12-10 2022-09-15 10X Genomics, Inc. Resolving spatial arrays using deconvolution
US12529094B2 (en) 2018-12-10 2026-01-20 10X Genomics, Inc. Imaging system hardware
WO2020219901A1 (en) * 2019-04-26 2020-10-29 10X Genomics, Inc. Imaging support devices
US12157124B2 (en) 2019-11-06 2024-12-03 10X Genomics, Inc. Imaging system hardware
US12405264B2 (en) * 2020-01-17 2025-09-02 10X Genomics, Inc. Electrophoretic system and method for analyte capture
US11768175B1 (en) 2020-03-04 2023-09-26 10X Genomics, Inc. Electrophoretic methods for spatial analysis
CN116134308B (en) 2020-05-19 2025-05-27 10X基因组学有限公司 Electrophoresis cartridge and instrument
EP4414459B1 (en) 2020-05-22 2025-09-03 10X Genomics, Inc. Simultaneous spatio-temporal measurement of gene expression and cellular activity
US12031177B1 (en) 2020-06-04 2024-07-09 10X Genomics, Inc. Methods of enhancing spatial resolution of transcripts
WO2021252747A1 (en) 2020-06-10 2021-12-16 1Ox Genomics, Inc. Fluid delivery methods
BR112022026979A2 (en) * 2020-07-14 2023-03-07 Illumina Inc MICROARRANGEMENTS, SEALS FOR HYBRIDIZATION AND RELATED METHODS
WO2022061150A2 (en) 2020-09-18 2022-03-24 10X Geonomics, Inc. Sample handling apparatus and image registration methods
WO2022098810A1 (en) * 2020-11-06 2022-05-12 10X Genomics, Inc. Assay support devices
EP4421491A3 (en) 2021-02-19 2024-11-27 10X Genomics, Inc. Method of using a modular assay support device
US12553805B2 (en) 2021-08-02 2026-02-17 10X Genomics, Inc. Methods of preserving a biological sample
USD1064308S1 (en) 2021-09-17 2025-02-25 10X Genomics, Inc. Sample handling device
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CN118272183A (en) * 2022-12-31 2024-07-02 深圳市新产业生物医学工程股份有限公司 Amplification board assembly and state detection method thereof
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Also Published As

Publication number Publication date
WO2008002951A2 (en) 2008-01-03
JP2009542222A (en) 2009-12-03
US20090253582A1 (en) 2009-10-08
EP2043785A2 (en) 2009-04-08

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