WO2008011056A3 - Device with integrated multi-fiber optical probe and methods of use - Google Patents

Device with integrated multi-fiber optical probe and methods of use Download PDF

Info

Publication number
WO2008011056A3
WO2008011056A3 PCT/US2007/016267 US2007016267W WO2008011056A3 WO 2008011056 A3 WO2008011056 A3 WO 2008011056A3 US 2007016267 W US2007016267 W US 2007016267W WO 2008011056 A3 WO2008011056 A3 WO 2008011056A3
Authority
WO
WIPO (PCT)
Prior art keywords
tissue
fiber optical
optical probe
fiber
endoscope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2007/016267
Other languages
French (fr)
Other versions
WO2008011056A2 (en
Inventor
Irving Bigio
Satish Singh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boston University
Original Assignee
Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston University filed Critical Boston University
Priority to JP2009520816A priority Critical patent/JP2009543663A/en
Priority to US12/374,175 priority patent/US20090326384A1/en
Priority to CA002658089A priority patent/CA2658089A1/en
Priority to AU2007275720A priority patent/AU2007275720A1/en
Priority to EP07796923A priority patent/EP2040612A2/en
Publication of WO2008011056A2 publication Critical patent/WO2008011056A2/en
Publication of WO2008011056A3 publication Critical patent/WO2008011056A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/415—Evaluating particular organs or parts of the immune or lymphatic systems the glands, e.g. tonsils, adenoids or thymus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0075—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/414—Evaluating particular organs or parts of the immune or lymphatic systems
    • A61B5/418—Evaluating particular organs or parts of the immune or lymphatic systems lymph vessels, ducts or nodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00057—Light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Endoscopes (AREA)

Abstract

Biopsy instruments are integrated with a multi-fiber optical probe adapted to perform diagnostic measurements. In addition to being able to analyze, treat or remove tissue, such integrated devices characterize tissue by measuring the amount of scattering and absorption of light transmitted into the tissue. Each fiberoptic probe has an illuminating fiber that provides a broadband light source for transmission into tissue, and a collecting fiber that collects the light scattered by the tissue and transmits the collected light to a spectrometer. One embodiment is an endoscope-mediated tool with a jaw-type biopsy forceps and a multi-fiber optical probe which is conveyed through a hollow central channel. Another embodiment is an endoscope-mediated tool with a jaw-type biopsy forceps and a plurality of multi-fiber optical probes. Yet another embodiment is an endoscopic polypectomy-type snare catheter with a multi- fiber optical probe located at the tip.
PCT/US2007/016267 2006-07-18 2007-07-18 Device with integrated multi-fiber optical probe and methods of use Ceased WO2008011056A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2009520816A JP2009543663A (en) 2006-07-18 2007-07-18 Apparatus with integrated multi-fiber optical probe and method of use
US12/374,175 US20090326384A1 (en) 2006-07-18 2007-07-18 Device With Integrated Multi-Fiber Optical Probe and Methods of Use
CA002658089A CA2658089A1 (en) 2006-07-18 2007-07-18 Device with integrated multi-fiber optical probe and methods of use
AU2007275720A AU2007275720A1 (en) 2006-07-18 2007-07-18 Device with integrated multi-fiber optical probe and methods of use
EP07796923A EP2040612A2 (en) 2006-07-18 2007-07-18 Device with integrated multi-fiber optical probe and methods of use

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83169906P 2006-07-18 2006-07-18
US60/831,699 2006-07-18

Publications (2)

Publication Number Publication Date
WO2008011056A2 WO2008011056A2 (en) 2008-01-24
WO2008011056A3 true WO2008011056A3 (en) 2008-07-03

Family

ID=38957342

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/016267 Ceased WO2008011056A2 (en) 2006-07-18 2007-07-18 Device with integrated multi-fiber optical probe and methods of use

Country Status (6)

Country Link
US (1) US20090326384A1 (en)
EP (1) EP2040612A2 (en)
JP (1) JP2009543663A (en)
AU (1) AU2007275720A1 (en)
CA (1) CA2658089A1 (en)
WO (1) WO2008011056A2 (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2280053T3 (en) * 2003-09-23 2007-09-01 Stichting Voor De Technische Wetenschappen PROCESS AND DEVICE FOR THE RETRODISPERSION SPECTROSCOPY.
US20090208143A1 (en) * 2008-02-19 2009-08-20 University Of Washington Efficient automated urothelial imaging using an endoscope with tip bending
WO2009111717A1 (en) * 2008-03-06 2009-09-11 Trustees Of Boston University Low cost disposable medical forceps to enable a hollow central channel for various functionalities
JP2010025867A (en) * 2008-07-23 2010-02-04 Olympus Medical Systems Corp Subject observation apparatus and subject observation method
KR101109968B1 (en) 2008-07-23 2012-02-17 올림푸스 메디칼 시스템즈 가부시키가이샤 Subject observation apparatus and subject observation method
EP2542145B1 (en) 2010-03-05 2020-08-12 The General Hospital Corporation Systems which provide microscopic images of at least one anatomical structure at a particular resolution
US9737320B2 (en) * 2010-03-18 2017-08-22 Covidien Lp Surgical grasper with integrated probe
CN102379727A (en) * 2011-09-02 2012-03-21 王宝根 Multifunctional biopsy forceps
WO2013071938A1 (en) 2011-11-16 2013-05-23 Coloplast A/S Operation device especially intended for proceeding to an operation inside the body of a living being
US10064554B2 (en) 2011-12-14 2018-09-04 The Trustees Of The University Of Pennsylvania Fiber optic flow and oxygenation monitoring using diffuse correlation and reflectance
CA2860026C (en) 2011-12-22 2021-03-30 Trustees Of Dartmouth College Biopsy device with integrated optical spectroscopy guidance
RU2014134029A (en) 2012-01-20 2016-03-20 Конинклейке Филипс Н.В. ELECTROSURGICAL SYSTEM, ELECTROSURGICAL DEVICE AND METHOD FOR OPERATION OF ELECTROSURGICAL SYSTEM
EP2814375B1 (en) * 2012-02-13 2020-04-08 Koninklijke Philips N.V. Photonic probe apparatus with integrated tissue marking facility
JP5774563B2 (en) 2012-09-04 2015-09-09 富士フイルム株式会社 ENDOSCOPE SYSTEM, PROCESSOR DEVICE THEREOF, AND METHOD FOR OPERATING ENDOSCOPY SYSTEM
JP5911649B2 (en) 2012-11-02 2016-04-27 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． System with photonic biopsy device for obtaining pathological information
US9824440B2 (en) * 2012-11-20 2017-11-21 Vanderbilt University Methods and systems for three-dimensional real-time intraoperative surgical margin evaluation of tumor tissues
WO2014120901A1 (en) * 2013-02-01 2014-08-07 Trustees Of Boston University Optically augmented fine needle aspiration biopsy device and method of using the same
US9907496B1 (en) 2013-06-25 2018-03-06 National Technology & Engineering Solutions Of Sandia, Llc Optoelectronic system and apparatus for connection to biological systems
WO2016035450A1 (en) * 2014-09-01 2016-03-10 株式会社島津製作所 Imaging device
CZ2014691A3 (en) 2014-10-10 2016-01-06 Oprox, A.S. Catheter for optical biopsy
WO2016118925A1 (en) * 2015-01-23 2016-07-28 The Regents Of The University Of California Facilitating real-time visualization of tissue features derived from optical signals
USD798443S1 (en) 2016-05-03 2017-09-26 Coloplast A/S Videoscope handle
WO2021026161A1 (en) * 2019-08-05 2021-02-11 Gyrus Acmi, Inc., D.B.A. Olympus Surgical Technologies America Laser control using a spectrometer
CN110840397A (en) * 2019-11-01 2020-02-28 福建师范大学 A device for endoscopic Raman spectroscopy detection of intracavity tissue
US20210346082A1 (en) * 2020-05-08 2021-11-11 Covidien Lp Robotic surgical instruments and methods
DE102021204907A1 (en) * 2021-05-14 2022-11-17 Richard Wolf Gmbh biopsy system
CN117279565A (en) * 2021-05-25 2023-12-22 贝鲁特美国大学 Non-invasive electromagnetic system for diagnosing and monitoring skin abnormalities in vivo and ex vivo

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5460182A (en) * 1992-09-14 1995-10-24 Sextant Medical Corporation Tissue penetrating apparatus and methods
WO1997041776A1 (en) * 1996-05-07 1997-11-13 Spectrascience, Inc. Optical biopsy forceps
WO1998001074A1 (en) * 1996-07-08 1998-01-15 Boston Scientific Corporation Diagnosing and performing interventional procedures on tissue in vivo
WO1999045838A1 (en) * 1998-03-09 1999-09-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
WO2001097902A2 (en) * 2000-06-19 2001-12-27 University Of Washington Medical imaging, diagnosis, and therapy using a scanning single optical fiber system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5460182A (en) * 1992-09-14 1995-10-24 Sextant Medical Corporation Tissue penetrating apparatus and methods
WO1997041776A1 (en) * 1996-05-07 1997-11-13 Spectrascience, Inc. Optical biopsy forceps
WO1998001074A1 (en) * 1996-07-08 1998-01-15 Boston Scientific Corporation Diagnosing and performing interventional procedures on tissue in vivo
WO1999045838A1 (en) * 1998-03-09 1999-09-16 Spectrascience, Inc. Optical biopsy system and methods for tissue diagnosis
WO2001097902A2 (en) * 2000-06-19 2001-12-27 University Of Washington Medical imaging, diagnosis, and therapy using a scanning single optical fiber system

Also Published As

Publication number Publication date
WO2008011056A2 (en) 2008-01-24
US20090326384A1 (en) 2009-12-31
EP2040612A2 (en) 2009-04-01
JP2009543663A (en) 2009-12-10
AU2007275720A8 (en) 2009-02-19
AU2007275720A1 (en) 2008-01-24
CA2658089A1 (en) 2008-01-24

Similar Documents

Publication Publication Date Title
WO2008011056A3 (en) Device with integrated multi-fiber optical probe and methods of use
WO2007090147A3 (en) Method and apparatus for measurement of optical properties in tissue
Chen Preclinical characterization of the Spyglass peroral cholangiopancreatoscopy system for direct access, visualization, and biopsy
WO2010028612A4 (en) Device for spectral analysis of parenchyma
GB2465316A (en) Optical spectroscopic device for the identification of cervical cancer
US20200085308A1 (en) Probe with a Removable Tip
WO2009051728A8 (en) Method and device for the optical spectroscopic identification of cervical cancer
RU2012133682A (en) APPARATUS FOR NON-INVASIVE ANALYSIS OF IN VITO BY MEANS OF Raman spectroscopy
WO2010083484A3 (en) System and method for characterization of oral, systemic and mucosal tissue utilizing raman spectroscopy
ATE352256T1 (en) FORCEPS FOR OPTICAL BIOPSY
WO2008121871A3 (en) Detecting optical properties of a turbid medium
ATE509581T1 (en) BIOPSY COLLECTION DEVICE
JP2015529100A (en) Diagnostic instrument and method for Raman spectroscopy
IL268516B1 (en) Brain clot characterization using optical signal analysis, and corresponding stent selection
WO2009132360A2 (en) Systems and methods for performing optical spectroscopy using a self-calibrating fiber optic probe
CN106413512B (en) Multi-point detection optical fiber sensor and insertion device with multi-point detection optical fiber sensor
CN101904737A (en) Live Fluorescence Endoscopic Spectral Imaging Device
CN209460144U (en) A Probe for Raman Spectroscopy in Fiber Optic Endoscopy
GB2548779A (en) Optical probes for corridor surgery
EP2759247A1 (en) Optical measurement apparatus and calibration method
JP6389828B2 (en) Optical device for use with a medical imaging device
CN109520998A (en) A kind of fiber Raman system for medical treatment detection
US9867557B2 (en) Probe
O'Brien et al. Development of a visually guided Raman spectroscopy probe for cervical assessment during pregnancy
CN204445794U (en) Endoscope and endoscope extend imaging device

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 12374175

Country of ref document: US

Ref document number: 2009520816

Country of ref document: JP

Ref document number: 2658089

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2007275720

Country of ref document: AU

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2007796923

Country of ref document: EP

ENP Entry into the national phase

Ref document number: 2007275720

Country of ref document: AU

Date of ref document: 20070718

Kind code of ref document: A

NENP Non-entry into the national phase

Ref country code: RU

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 07796923

Country of ref document: EP

Kind code of ref document: A2