WO2008046405A3 - Behandlung von osteoporose - Google Patents

Behandlung von osteoporose Download PDF

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Publication number
WO2008046405A3
WO2008046405A3 PCT/DE2007/001853 DE2007001853W WO2008046405A3 WO 2008046405 A3 WO2008046405 A3 WO 2008046405A3 DE 2007001853 W DE2007001853 W DE 2007001853W WO 2008046405 A3 WO2008046405 A3 WO 2008046405A3
Authority
WO
WIPO (PCT)
Prior art keywords
treatment
combination
osteoporosis
implants
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/DE2007/001853
Other languages
English (en)
French (fr)
Other versions
WO2008046405A2 (de
Inventor
Georg Gradl
Detlef Behrend
Klaus-Peter Schmitz
Katrin Sternberg
Kathleen Schmohl
Sven Kramer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Rostock
Original Assignee
University of Rostock
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/DE2007/000192 external-priority patent/WO2007090373A2/de
Application filed by University of Rostock filed Critical University of Rostock
Priority to EP07817688A priority Critical patent/EP2094323B1/de
Priority to US12/445,635 priority patent/US8496971B2/en
Priority to AT07817688T priority patent/ATE534414T1/de
Publication of WO2008046405A2 publication Critical patent/WO2008046405A2/de
Anticipated expiration legal-status Critical
Publication of WO2008046405A3 publication Critical patent/WO2008046405A3/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y110/00—Oxidoreductases acting on diphenols and related substances as donors (1.10)
    • C12Y110/03—Oxidoreductases acting on diphenols and related substances as donors (1.10) with an oxygen as acceptor (1.10.3)
    • C12Y110/03002—Laccase (1.10.3.2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Composite Materials (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Die vorliegende Erfindung betrifft eine Kombination zur Behandlung von Osteoporose und/oder zur Prophylaxe und Behandlung von Knochenbrüchen, welche Kollagen, zusätzliches Peptid, eine Calcium-haltige Substanz und ein Vernetzungsmittel mit einem endständig funktionalisierten Oligolacton umfasst. Gegenstand der Erfindung sind auch aus der Kombination hergestellte künstliche Knochen und Implantate und die Verwendung der Kombination zur Fixierung von Implantaten sowie zur Behandlung von Osteoporose und/oder Prophylaxe und Behandlung von Knochenbrüchen. Ferner betrifft die Erfindung ein Verfahren zur Herstellung künstlicher Knochen und Implantate.
PCT/DE2007/001853 2006-10-16 2007-10-16 Behandlung von osteoporose Ceased WO2008046405A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP07817688A EP2094323B1 (de) 2006-10-16 2007-10-16 Behandlung von osteoporose
US12/445,635 US8496971B2 (en) 2006-10-16 2007-10-16 Treatment of osteoporosis
AT07817688T ATE534414T1 (de) 2006-10-16 2007-10-16 Behandlung von osteoporose

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102006048833.4 2006-10-16
DE102006048833A DE102006048833A1 (de) 2006-10-16 2006-10-16 Behandlung von Osteoporose
DEPCT/DE2007/000192 2007-02-02
PCT/DE2007/000192 WO2007090373A2 (de) 2006-02-09 2007-02-02 Neue klebstoffe für medizinische anwendungen

Publications (2)

Publication Number Publication Date
WO2008046405A2 WO2008046405A2 (de) 2008-04-24
WO2008046405A3 true WO2008046405A3 (de) 2009-05-14

Family

ID=39184998

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2007/001853 Ceased WO2008046405A2 (de) 2006-10-16 2007-10-16 Behandlung von osteoporose

Country Status (5)

Country Link
US (1) US8496971B2 (de)
EP (1) EP2094323B1 (de)
AT (1) ATE534414T1 (de)
DE (1) DE102006048833A1 (de)
WO (1) WO2008046405A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9801905B2 (en) 2014-03-13 2017-10-31 Hossam Abdel Salam El Sayed Mohamed Use of organic sulphur, antioxidants, and amino acids in conjunction with exercise and electromagnetic stimulation to treat osteoporosis
KR102096146B1 (ko) 2014-09-02 2020-04-28 애플 인크. 가변 햅틱 출력을 위한 시맨틱 프레임워크
EP3210596A1 (de) 2016-02-29 2017-08-30 G.L. Pharma GmbH Missbrauchsverhindernde pharmazeutische zusammensetzung
EP3210630A1 (de) 2016-02-29 2017-08-30 G.L. Pharma GmbH Missbrauch-abschreckende pharmazeutische zusammensetzungen
EP3231420A1 (de) 2016-02-29 2017-10-18 G.L. Pharma GmbH Missbrauchsverhindernde pharmazeutische zusammensetzungen
DK179823B1 (en) 2016-06-12 2019-07-12 Apple Inc. DEVICES, METHODS, AND GRAPHICAL USER INTERFACES FOR PROVIDING HAPTIC FEEDBACK
DK201670737A1 (en) 2016-06-12 2018-01-22 Apple Inc Devices, Methods, and Graphical User Interfaces for Providing Haptic Feedback
DK201670720A1 (en) 2016-09-06 2018-03-26 Apple Inc Devices, Methods, and Graphical User Interfaces for Generating Tactile Outputs
DE102016222603A1 (de) * 2016-11-16 2018-05-17 Aesculap Ag Implantat und ein Kit zum Behandeln eines Knochendefekts
DK201770372A1 (en) 2017-05-16 2019-01-08 Apple Inc. TACTILE FEEDBACK FOR LOCKED DEVICE USER INTERFACES
US11998654B2 (en) 2018-07-12 2024-06-04 Bard Shannon Limited Securing implants and medical devices
DE102018126394B4 (de) 2018-10-23 2020-12-24 Universität Rostock Probiotika enthaltendes Depotsystem für dentale Anwendungen
WO2023044042A2 (en) 2021-09-17 2023-03-23 ASC Engineered Solutions, LLC Pipe groover

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583114A (en) * 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
US20040249015A1 (en) * 2000-08-11 2004-12-09 Weitao Jia Method of manufacturing dental restorations
EP1518569A1 (de) * 2003-08-27 2005-03-30 Coripharm Medizinprodukte GmbH & Co. KG. Implantatmaterial für den Knochen-Knorpel-Ersatz
WO2007090373A2 (de) * 2006-02-09 2007-08-16 Universität Rostock Neue klebstoffe für medizinische anwendungen

Family Cites Families (16)

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EP0164483B1 (de) 1984-06-12 1989-08-16 Oscobal Ag Verfahren zur Herstellung von Knochenersatzmaterial
JPS6323670A (ja) 1986-04-25 1988-01-30 バイオ−ポリマ−ズ　インコ−ポレ−テツド 接着・被覆組成物とその使用方法
ATE215562T1 (de) 1991-12-30 2002-04-15 Norian Corp Mineralisiertes kollagen
US5320844A (en) * 1992-03-12 1994-06-14 Liu Sung Tsuen Composite materials for hard tissue replacement
AU7109494A (en) 1993-06-16 1995-01-03 Enzon, Inc. Conjugated biodhesives
US5776193A (en) * 1995-10-16 1998-07-07 Orquest, Inc. Bone grafting matrix
DE19803673A1 (de) 1998-01-30 1999-08-05 Norbert M Dr Meenen Biohybrider Gelenkflächenersatz
JP4137224B2 (ja) 1998-03-31 2008-08-20 天野エンザイム株式会社 酵素による蛋白質の架橋法
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US6949251B2 (en) * 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
WO2003008376A2 (en) 2001-07-20 2003-01-30 Northwestern University Adhesive dopa-containing polymers and related methods of use
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EP1799277B1 (de) * 2004-09-14 2012-11-07 Agency for Science, Technology and Research Poröser verbundwerkstoff aus biologischem material und füllstoff und verfahren zu seiner herstellung

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5583114A (en) * 1994-07-27 1996-12-10 Minnesota Mining And Manufacturing Company Adhesive sealant composition
US20040249015A1 (en) * 2000-08-11 2004-12-09 Weitao Jia Method of manufacturing dental restorations
EP1518569A1 (de) * 2003-08-27 2005-03-30 Coripharm Medizinprodukte GmbH & Co. KG. Implantatmaterial für den Knochen-Knorpel-Ersatz
WO2007090373A2 (de) * 2006-02-09 2007-08-16 Universität Rostock Neue klebstoffe für medizinische anwendungen

Also Published As

Publication number Publication date
EP2094323B1 (de) 2011-11-23
WO2008046405A2 (de) 2008-04-24
ATE534414T1 (de) 2011-12-15
DE102006048833A1 (de) 2008-04-17
US8496971B2 (en) 2013-07-30
EP2094323A2 (de) 2009-09-02
US20110027381A1 (en) 2011-02-03

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