WO2008088008A1 - 消化管機能異常症予防及び／又は治療剤 - Google Patents

消化管機能異常症予防及び／又は治療剤 Download PDF

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Publication number
WO2008088008A1
WO2008088008A1 PCT/JP2008/050515 JP2008050515W WO2008088008A1 WO 2008088008 A1 WO2008088008 A1 WO 2008088008A1 JP 2008050515 W JP2008050515 W JP 2008050515W WO 2008088008 A1 WO2008088008 A1 WO 2008088008A1
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WO
WIPO (PCT)
Prior art keywords
fermentation product
functional dyspepsia
prophylactic
found
effect
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/050515
Other languages
English (en)
French (fr)
Inventor
Masayuki Uchida
Shigeru Yamato
Hajime Ariga
Hirotsugu Uehara
Tomofumi Amano
Keiko Morikubo
Kaori Yoshida
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Meiji Dairies Corp
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Meiji Dairies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Dairies Corp filed Critical Meiji Dairies Corp
Priority to KR1020097016787A priority Critical patent/KR101459166B1/ko
Priority to US12/523,010 priority patent/US9675647B2/en
Priority to CA2675729A priority patent/CA2675729C/en
Priority to HK10107305.3A priority patent/HK1140937B/xx
Priority to EP08703370A priority patent/EP2110133B1/en
Priority to CN2008800086058A priority patent/CN101646444B/zh
Priority to JP2008554072A priority patent/JPWO2008088008A1/ja
Priority to AT08703370T priority patent/ATE521358T1/de
Publication of WO2008088008A1 publication Critical patent/WO2008088008A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

　本発明者らは鋭意検討した結果、in vitro試験および過敏性腸症候群患者を用いた試験において、プロピオン酸菌発酵物が消化管機能異常症に対する予防／治療効果を有することを見出し、本発明を完成させた。具体的には、in vitro試験において、遠位部大腸特異的に、腸の収縮力を変動させず、かつ腸の収縮頻度を高める作用を有することを見出し、さらに過敏性腸症候群患者の排便状況、全般的な腹部状態、健康関連QOLの改善効果を見出した。また、プロピオン酸菌発酵物は大量に摂取することも可能である。よって、プロピオン酸菌発酵物は、安全に消化管機能異常症に対する予防／治療する効果を期待できる。
PCT/JP2008/050515 2007-01-17 2008-01-17 消化管機能異常症予防及び／又は治療剤 Ceased WO2008088008A1 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
KR1020097016787A KR101459166B1 (ko) 2007-01-17 2008-01-17 소화관기능 이상증 예방 및/또는 치료제
US12/523,010 US9675647B2 (en) 2007-01-17 2008-01-17 Prophylactic and/or therapeutic agent for functional gastrointestinal disorders
CA2675729A CA2675729C (en) 2007-01-17 2008-01-17 Prophylactic and/or therapeutic agent for functional gastrointestinal disorders
HK10107305.3A HK1140937B (en) 2007-01-17 2008-01-17 Prophylactic and/or therapeutic agent for functional dyspepsia
EP08703370A EP2110133B1 (en) 2007-01-17 2008-01-17 Prophylactic and/or therapeutic agent for functional gastrointestinal disorders
CN2008800086058A CN101646444B (zh) 2007-01-17 2008-01-17 功能性胃肠病预防和/或治疗剂
JP2008554072A JPWO2008088008A1 (ja) 2007-01-17 2008-01-17 消化管機能異常症予防及び／又は治療剤
AT08703370T ATE521358T1 (de) 2007-01-17 2008-01-17 Vorbeugender und/oder therapeutischer wirkstoff zur behandlung einer funktionellen gastrointestinalen erkrankung

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007007628 2007-01-17
JP2007-007628 2007-01-17

Publications (1)

Publication Number Publication Date
WO2008088008A1 true WO2008088008A1 (ja) 2008-07-24

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Family Applications (1)

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PCT/JP2008/050515 Ceased WO2008088008A1 (ja) 2007-01-17 2008-01-17 消化管機能異常症予防及び／又は治療剤

Country Status (9)

Country Link
US (1) US9675647B2 (ja)
EP (1) EP2110133B1 (ja)
JP (1) JPWO2008088008A1 (ja)
KR (1) KR101459166B1 (ja)
CN (1) CN101646444B (ja)
AT (1) ATE521358T1 (ja)
CA (1) CA2675729C (ja)
ES (1) ES2367880T3 (ja)
WO (1) WO2008088008A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011071134A1 (ja) * 2009-12-10 2011-06-16 明治乳業株式会社 インフルエンザ感染症の予防組成物
WO2014163031A1 (ja) * 2013-04-01 2014-10-09 株式会社明治 即効性の整腸剤
JPWO2022124324A1 (ja) * 2020-12-09 2022-06-16

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11179427B2 (en) 2013-01-21 2021-11-23 Eth Zurich Baby food composition comprising viable propionic acid-producing bacteria
WO2016183535A1 (en) 2015-05-14 2016-11-17 University Of Puerto Rico Methods for restoring microbiota of newborns
WO2017117142A1 (en) 2015-12-28 2017-07-06 New York University Device and method of restoring microbiota of newborns
WO2017164275A1 (ja) * 2016-03-24 2017-09-28 株式会社明治 口腔内環境改善用組成物
WO2018008895A1 (ko) 2016-07-08 2018-01-11 주식회사 엠디헬스케어 프로피오니박테리움 속 세균 유래 나노소포 및 이의 용도
KR101923969B1 (ko) 2016-07-08 2018-11-30 주식회사 엠디헬스케어 프로피오니박테리움 속 세균 유래 나노소포 및 이의 용도
WO2023276702A1 (ja) 2021-06-29 2023-01-05 大塚化学株式会社 エポキシ樹脂改質剤、これを含有するエポキシ樹脂組成物、エポキシ樹脂組成物からなる接着剤、およびエポキシ樹脂組成物を硬化してなる樹脂硬化物

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001028547A1 (en) 1999-10-19 2001-04-26 Meiji Milk Products Co., Ltd Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials
WO2003016544A1 (fr) 2001-08-10 2003-02-27 Meiji Dairies Corporation Procede d'elaboration d'acide 1,4-dihydroxy-2-naphtoique
US20040005304A1 (en) * 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
US20040170617A1 (en) * 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
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WO2005030229A1 (en) * 2003-10-01 2005-04-07 Commonwealth Scientific & Industrial Research Organisation Probiotic storage and delivery
WO2005099725A1 (ja) 2004-04-13 2005-10-27 Meiji Dairies Corporation 炎症性腸疾患予防および／または治療剤
JP2006501281A (ja) * 2002-09-26 2006-01-12 プロバイオヘルス・エルエルシー 油乳化プロバイオティックカプセル封入物のプレバイオティックおよび保存的使用

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JP3315826B2 (ja) 1994-04-26 2002-08-19 明治乳業株式会社 ビフィズス菌増殖促進組成物

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001028547A1 (en) 1999-10-19 2001-04-26 Meiji Milk Products Co., Ltd Food materials useful in preventing and ameliorating metabolic bone diseases and preventives/remedies for metabolic bone diseases comprising these materials
US20040170617A1 (en) * 2000-06-05 2004-09-02 Finegold Sydney M. Method of treating diseases associated with abnormal gastrointestinal flora
JP2005508617A (ja) * 2001-07-26 2005-04-07 アリメンタリー・ヘルス・リミテッド プロバイオティックビフィドバクテリウム株類
WO2003016544A1 (fr) 2001-08-10 2003-02-27 Meiji Dairies Corporation Procede d'elaboration d'acide 1,4-dihydroxy-2-naphtoique
US20040005304A1 (en) * 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
JP2006501281A (ja) * 2002-09-26 2006-01-12 プロバイオヘルス・エルエルシー 油乳化プロバイオティックカプセル封入物のプレバイオティックおよび保存的使用
WO2005030229A1 (en) * 2003-10-01 2005-04-07 Commonwealth Scientific & Industrial Research Organisation Probiotic storage and delivery
WO2005099725A1 (ja) 2004-04-13 2005-10-27 Meiji Dairies Corporation 炎症性腸疾患予防および／または治療剤

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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011071134A1 (ja) * 2009-12-10 2011-06-16 明治乳業株式会社 インフルエンザ感染症の予防組成物
CN102665738A (zh) * 2009-12-10 2012-09-12 株式会社明治 用于预防流感感染的组合物
JPWO2011071134A1 (ja) * 2009-12-10 2013-04-22 株式会社明治 インフルエンザ感染症の予防組成物
TWI476000B (zh) * 2009-12-10 2015-03-11 Meiji Co Ltd Production of Propionic Acid Bacteria in the Preparation of Preventive Agents for Influenza Infectious Diseases and Induction Promoters for Neutralizing Antibodies
WO2014163031A1 (ja) * 2013-04-01 2014-10-09 株式会社明治 即効性の整腸剤
JPWO2014163031A1 (ja) * 2013-04-01 2017-02-16 株式会社明治 即効性の整腸剤
JPWO2022124324A1 (ja) * 2020-12-09 2022-06-16
WO2022124324A1 (ja) * 2020-12-09 2022-06-16 株式会社明治 アシディプロピオニバクテリウム属菌またはその処理物を含んでなる組成物

Also Published As

Publication number Publication date
EP2110133A4 (en) 2010-05-19
HK1140937A1 (en) 2010-10-29
JPWO2008088008A1 (ja) 2010-05-13
EP2110133A1 (en) 2009-10-21
ES2367880T3 (es) 2011-11-10
KR101459166B1 (ko) 2014-11-07
KR20090101961A (ko) 2009-09-29
CA2675729A1 (en) 2008-07-24
CA2675729C (en) 2015-05-12
US20100040698A1 (en) 2010-02-18
EP2110133B1 (en) 2011-08-24
US9675647B2 (en) 2017-06-13
CN101646444B (zh) 2013-11-06
CN101646444A (zh) 2010-02-10
ATE521358T1 (de) 2011-09-15

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