WO2008092011A3 - Biofilm-inhibiting medical products - Google Patents

Biofilm-inhibiting medical products Download PDF

Info

Publication number
WO2008092011A3
WO2008092011A3 PCT/US2008/051924 US2008051924W WO2008092011A3 WO 2008092011 A3 WO2008092011 A3 WO 2008092011A3 US 2008051924 W US2008051924 W US 2008051924W WO 2008092011 A3 WO2008092011 A3 WO 2008092011A3
Authority
WO
WIPO (PCT)
Prior art keywords
biofilm
inhibiting
medical products
inhibiting medical
medical product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/051924
Other languages
French (fr)
Other versions
WO2008092011A2 (en
Inventor
Brian L Bates
Michael C Hiles
Chad E Johnson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cook Inc
Cook Biotech Inc
Original Assignee
Cook Inc
Cook Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cook Inc, Cook Biotech Inc filed Critical Cook Inc
Priority to CA2678449A priority Critical patent/CA2678449C/en
Priority to EP08728224.0A priority patent/EP2117611B1/en
Priority to AU2008207864A priority patent/AU2008207864B2/en
Publication of WO2008092011A2 publication Critical patent/WO2008092011A2/en
Anticipated expiration legal-status Critical
Publication of WO2008092011A3 publication Critical patent/WO2008092011A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/40—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing ingredients of undetermined constitution or reaction products thereof, e.g. plant or animal extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0057—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/005—Ingredients of undetermined constitution or reaction products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/216—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with other specific functional groups, e.g. aldehydes, ketones, phenols, quaternary phosphonium groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A biofilm-inhibiting medical product includes a carrier formed from a natural, bioremodelable material, whereby the carrier includes a biocidal bismuth thiol agent and/or one or more other biofilm-inhibiting or wound healing agents. A method for using the biofilm-inhibiting medical product to treat a wound or tissue defect in a patient's body is described.
PCT/US2008/051924 2007-01-24 2008-01-24 Biofilm-inhibiting medical products Ceased WO2008092011A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA2678449A CA2678449C (en) 2007-01-24 2008-01-24 Biofilm-inhibiting medical products
EP08728224.0A EP2117611B1 (en) 2007-01-24 2008-01-24 Biofilm-inhibiting medical products
AU2008207864A AU2008207864B2 (en) 2007-01-24 2008-01-24 Biofilm-inhibiting medical products

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89711407P 2007-01-24 2007-01-24
US60/897,114 2007-01-24

Publications (2)

Publication Number Publication Date
WO2008092011A2 WO2008092011A2 (en) 2008-07-31
WO2008092011A3 true WO2008092011A3 (en) 2009-08-13

Family

ID=39529801

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/051924 Ceased WO2008092011A2 (en) 2007-01-24 2008-01-24 Biofilm-inhibiting medical products

Country Status (4)

Country Link
EP (1) EP2117611B1 (en)
AU (1) AU2008207864B2 (en)
CA (1) CA2678449C (en)
WO (1) WO2008092011A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9408393B2 (en) 2010-02-03 2016-08-09 Microbion Corporation Bismuth-thiols as antiseptics for agricultural, industrial and other uses
EP2393491B1 (en) 2009-02-03 2020-04-22 Microbion Corporation Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
US9028878B2 (en) 2009-02-03 2015-05-12 Microbion Corporation Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
KR101966867B1 (en) * 2010-02-03 2019-04-08 마이크로비온 코포레이션 Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
RU2694758C2 (en) * 2012-12-20 2019-07-16 Раджив Бхушан Antimicrobial compositions
AU2015231110B2 (en) * 2014-03-21 2019-03-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
CN107890586B (en) * 2017-10-27 2021-06-01 百澳瑞派（天津）生物科技有限公司 Preparation method of allogeneic biological breast patch
AU2019312592B2 (en) 2018-07-31 2025-06-26 Microbion Corporation Bismuth-thiol compositions and methods for treating wounds
WO2020028558A1 (en) 2018-07-31 2020-02-06 Microbion Corporation Bismuth-thiol compositions and methods of use

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6086921A (en) * 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
US20050013870A1 (en) * 2003-07-17 2005-01-20 Toby Freyman Decellularized extracellular matrix of conditioned body tissues and uses thereof
WO2005020847A2 (en) * 2003-08-25 2005-03-10 Cook Biotech Incorporated Graft materials containing bioactive substances, and methods for their manufacture
US20060045899A1 (en) * 2004-08-25 2006-03-02 Shantha Sarangapani Antimicrobial composition for medical articles
WO2006044512A1 (en) * 2004-10-15 2006-04-27 Cook Biotech Incorporated Fibronectin-modified ecm tissue graft constructs and methods for preparation and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2317313T3 (en) * 2004-10-19 2009-04-16 Krka, Tovarna Zdravil, D.D., Novo Mesto SOLID PHARMACEUTICAL COMPOSITION INCLUDING DONEPEZIL CHLORHYDRATE.

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6086921A (en) * 1995-04-25 2000-07-11 Wintrop-University Hospital Metal/thiol biocides
US20050013870A1 (en) * 2003-07-17 2005-01-20 Toby Freyman Decellularized extracellular matrix of conditioned body tissues and uses thereof
WO2005020847A2 (en) * 2003-08-25 2005-03-10 Cook Biotech Incorporated Graft materials containing bioactive substances, and methods for their manufacture
US20060045899A1 (en) * 2004-08-25 2006-03-02 Shantha Sarangapani Antimicrobial composition for medical articles
WO2006044512A1 (en) * 2004-10-15 2006-04-27 Cook Biotech Incorporated Fibronectin-modified ecm tissue graft constructs and methods for preparation and use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HONGJUN ZHANG ET AL: "Inhibition of Bacterial Adherence on the Surface of Stents and Bacterial Growth in Bile by Bismuth Dimercaprol", DIGESTIVE DISEASES AND SCIENCES, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 50, no. 6, 1 June 2005 (2005-06-01), pages 1046 - 1051, XP019237369, ISSN: 1573-2568 *

Also Published As

Publication number Publication date
WO2008092011A2 (en) 2008-07-31
CA2678449A1 (en) 2008-07-31
CA2678449C (en) 2012-09-18
EP2117611A2 (en) 2009-11-18
EP2117611B1 (en) 2014-07-30
AU2008207864A1 (en) 2008-07-31
AU2008207864B2 (en) 2013-07-11

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