WO2008111573A1 - 成長ホルモン分泌促進剤 - Google Patents

成長ホルモン分泌促進剤 Download PDF

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Publication number
WO2008111573A1
WO2008111573A1 PCT/JP2008/054338 JP2008054338W WO2008111573A1 WO 2008111573 A1 WO2008111573 A1 WO 2008111573A1 JP 2008054338 W JP2008054338 W JP 2008054338W WO 2008111573 A1 WO2008111573 A1 WO 2008111573A1
Authority
WO
WIPO (PCT)
Prior art keywords
growth hormone
secretion
hormone secretion
stimulator
secretion stimulator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/054338
Other languages
English (en)
French (fr)
Inventor
Aiko Ono
Hiroaki Matsuyama
Yoshikazu Morita
Atsushi Serizawa
Satoshi Higurashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Snow Brand Milk Products Co Ltd
Original Assignee
Snow Brand Milk Products Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Snow Brand Milk Products Co Ltd filed Critical Snow Brand Milk Products Co Ltd
Priority to AU2008225454A priority Critical patent/AU2008225454B2/en
Priority to JP2009504051A priority patent/JP5247678B2/ja
Priority to CA002680818A priority patent/CA2680818A1/en
Priority to EP08721754A priority patent/EP2133090A4/en
Priority to NZ579490A priority patent/NZ579490A/en
Priority to US12/531,227 priority patent/US20100087372A1/en
Priority to CN200880008006.6A priority patent/CN101646448B/zh
Publication of WO2008111573A1 publication Critical patent/WO2008111573A1/ja
Anticipated expiration legal-status Critical
Priority to US13/045,183 priority patent/US20110165139A1/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/40—Transferrins, e.g. lactoferrins, ovotransferrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/018—Hydrolysed proteins; Derivatives thereof from animals from milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Preparation or treatment thereof
    • A23L2/52—Adding ingredients
    • A23L2/66—Proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/19—Dairy proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/20—Milk; Whey; Colostrum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

　　乳由来の塩基性タンパク質画分を有効成分とする、成長ホルモン分泌促進作用を有するグレリンの分泌促進を介したものである、成長ホルモン分泌促進剤、及び乳由来の塩基性タンパク質画分を用いてグレリンの分泌を促進する方法。本成長ホルモン分泌促進剤は日常的に摂取でき、長期にわたって摂取しても安全性が高い。
PCT/JP2008/054338 2007-03-12 2008-03-11 成長ホルモン分泌促進剤 Ceased WO2008111573A1 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU2008225454A AU2008225454B2 (en) 2007-03-12 2008-03-11 Growth hormone secretion stimulator
JP2009504051A JP5247678B2 (ja) 2007-03-12 2008-03-11 成長ホルモン分泌促進剤
CA002680818A CA2680818A1 (en) 2007-03-12 2008-03-11 Growth hormone secretion stimulator
EP08721754A EP2133090A4 (en) 2007-03-12 2008-03-11 GROWTH HORMONE SECRETION STIMULATOR
NZ579490A NZ579490A (en) 2007-03-12 2008-03-11 Growth hormone secretion stimulator comprising milk-derived basic fraction
US12/531,227 US20100087372A1 (en) 2007-03-12 2008-03-11 Growth hormone secretion stimulator
CN200880008006.6A CN101646448B (zh) 2007-03-12 2008-03-11 生长激素分泌促进剂
US13/045,183 US20110165139A1 (en) 2007-03-12 2011-03-10 Growth hormone secretion stimulator

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007062372 2007-03-12
JP2007-062372 2007-03-12

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US13/045,183 Division US20110165139A1 (en) 2007-03-12 2011-03-10 Growth hormone secretion stimulator

Publications (1)

Publication Number Publication Date
WO2008111573A1 true WO2008111573A1 (ja) 2008-09-18

Family

ID=39759508

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054338 Ceased WO2008111573A1 (ja) 2007-03-12 2008-03-11 成長ホルモン分泌促進剤

Country Status (9)

Country Link
US (2) US20100087372A1 (ja)
EP (1) EP2133090A4 (ja)
JP (1) JP5247678B2 (ja)
KR (1) KR20090119785A (ja)
CN (1) CN101646448B (ja)
AU (1) AU2008225454B2 (ja)
CA (1) CA2680818A1 (ja)
NZ (1) NZ579490A (ja)
WO (1) WO2008111573A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010119088A3 (en) * 2009-04-15 2011-06-30 Bodo Melnik Milk and milk-based products modified to exhibit a reduced insulinemic index and/or reduced mitogenic activity
WO2014157153A1 (ja) * 2013-03-28 2014-10-02 雪印メグミルク株式会社 筋萎縮防止剤
WO2015008836A1 (ja) * 2013-07-19 2015-01-22 雪印メグミルク株式会社 筋萎縮防止及び／又は筋合成促進剤
WO2015199192A1 (ja) * 2014-06-25 2015-12-30 株式会社明治 グレリン分泌促進剤
JPWO2020218450A1 (ja) * 2019-04-26 2020-10-29
WO2021107080A1 (ja) * 2019-11-28 2021-06-03 国立大学法人京都大学 ペプチド

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010058679A1 (ja) * 2008-11-18 2010-05-27 国立大学法人 九州大学 骨折修復促進剤

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61246198A (ja) 1985-02-07 1986-11-01 オレオフイナ・ソシエテ・アノニム 蛋白の精製法
JPS63255300A (ja) 1987-04-10 1988-10-21 Snow Brand Milk Prod Co Ltd 硫酸エステル化物を用いて乳からラクトフエリンを分離、精製する方法
JPS6486839A (en) 1987-06-19 1989-03-31 Entamonto Sa Method for selectively extracting metal protein from whey
WO1992000994A1 (en) * 1990-07-13 1992-01-23 Gropep Pty. Ltd. Growth-promoting agent
JPH05202098A (ja) 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
JPH11315014A (ja) * 1998-04-30 1999-11-16 Snow Brand Milk Prod Co Ltd 歯周病予防及び改善剤
JP2002212097A (ja) * 2001-01-16 2002-07-31 Snow Brand Milk Prod Co Ltd 脂質代謝改善剤
JP2002212096A (ja) * 2001-01-16 2002-07-31 Snow Brand Milk Prod Co Ltd 血圧降下剤
WO2004004772A1 (ja) 2002-07-05 2004-01-15 Chugai Seiyaku Kabushiki Kaisha 糖尿病治療剤
JP2004115509A (ja) * 2002-09-05 2004-04-15 Snow Brand Milk Prod Co Ltd 破骨細胞分化抑制因子産生促進剤
JP2005507949A (ja) 2001-11-08 2005-03-24 サールテック アイ イェーテボリ アクチボラゲット うっ血性心不全の治療
JP2005082489A (ja) 2003-09-04 2005-03-31 Kyoto Univ 新規な摂食促進ペプチド、新規な成長ホルモン分泌促進ペプチド
JP2005535707A (ja) 2002-08-09 2005-11-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス 成長ホルモン放出ペプチド
JP2006347946A (ja) * 2005-06-15 2006-12-28 Fuji Oil Co Ltd 成長ホルモン分泌促進組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3112637B2 (ja) * 1994-09-30 2000-11-27 雪印乳業株式会社 骨強化剤
JP2974604B2 (ja) * 1996-01-23 1999-11-10 雪印乳業株式会社 塩基性タンパク質組成物、塩基性ペプチド組成物及びその利用
US20030040475A1 (en) * 2001-01-16 2003-02-27 Yasuhiro Toba Agents for improving lipid metabolism and reducing high blood pressure
FR2841747B1 (fr) * 2002-07-02 2004-08-20 Cie Laitiere Europeenne Isolat de proteines de lait et procede pour sa preparation
CA2523098C (en) * 2003-05-07 2011-06-21 Megmilk Snow Brand Co., Ltd. Skin collagen production promoter
KR100509681B1 (ko) * 2005-05-27 2005-08-23 주식회사 렉스진바이오텍 포유동물의 초유 또는 유즙 유래의 유청분리분획을포함하는 성장 촉진용 식품 조성물

Patent Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61246198A (ja) 1985-02-07 1986-11-01 オレオフイナ・ソシエテ・アノニム 蛋白の精製法
JPS63255300A (ja) 1987-04-10 1988-10-21 Snow Brand Milk Prod Co Ltd 硫酸エステル化物を用いて乳からラクトフエリンを分離、精製する方法
JPS6486839A (en) 1987-06-19 1989-03-31 Entamonto Sa Method for selectively extracting metal protein from whey
WO1992000994A1 (en) * 1990-07-13 1992-01-23 Gropep Pty. Ltd. Growth-promoting agent
JPH05202098A (ja) 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
JPH11315014A (ja) * 1998-04-30 1999-11-16 Snow Brand Milk Prod Co Ltd 歯周病予防及び改善剤
JP2002212097A (ja) * 2001-01-16 2002-07-31 Snow Brand Milk Prod Co Ltd 脂質代謝改善剤
JP2002212096A (ja) * 2001-01-16 2002-07-31 Snow Brand Milk Prod Co Ltd 血圧降下剤
JP2005507949A (ja) 2001-11-08 2005-03-24 サールテック アイ イェーテボリ アクチボラゲット うっ血性心不全の治療
WO2004004772A1 (ja) 2002-07-05 2004-01-15 Chugai Seiyaku Kabushiki Kaisha 糖尿病治療剤
JP2005535707A (ja) 2002-08-09 2005-11-24 ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス 成長ホルモン放出ペプチド
JP2004115509A (ja) * 2002-09-05 2004-04-15 Snow Brand Milk Prod Co Ltd 破骨細胞分化抑制因子産生促進剤
JP2005082489A (ja) 2003-09-04 2005-03-31 Kyoto Univ 新規な摂食促進ペプチド、新規な成長ホルモン分泌促進ペプチド
JP2006347946A (ja) * 2005-06-15 2006-12-28 Fuji Oil Co Ltd 成長ホルモン分泌促進組成物

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
NATURE, vol. 402, 1999, pages 656 - 660
NATURE, vol. 409, 2001, pages 194 - 198

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010119088A3 (en) * 2009-04-15 2011-06-30 Bodo Melnik Milk and milk-based products modified to exhibit a reduced insulinemic index and/or reduced mitogenic activity
WO2014157153A1 (ja) * 2013-03-28 2014-10-02 雪印メグミルク株式会社 筋萎縮防止剤
JP2014193821A (ja) * 2013-03-28 2014-10-09 Snow Brand Milk Products Co Ltd 筋萎縮防止剤
WO2015008836A1 (ja) * 2013-07-19 2015-01-22 雪印メグミルク株式会社 筋萎縮防止及び／又は筋合成促進剤
WO2015199192A1 (ja) * 2014-06-25 2015-12-30 株式会社明治 グレリン分泌促進剤
JPWO2020218450A1 (ja) * 2019-04-26 2020-10-29
JP7318897B2 (ja) 2019-04-26 2023-08-01 国立大学法人京都大学 ペプチド、組成物、及びグレリン分泌促進剤
WO2021107080A1 (ja) * 2019-11-28 2021-06-03 国立大学法人京都大学 ペプチド

Also Published As

Publication number Publication date
JP5247678B2 (ja) 2013-07-24
AU2008225454A1 (en) 2008-09-18
CA2680818A1 (en) 2008-09-18
CN101646448B (zh) 2017-02-08
US20100087372A1 (en) 2010-04-08
AU2008225454B2 (en) 2014-02-27
CN101646448A (zh) 2010-02-10
EP2133090A1 (en) 2009-12-16
KR20090119785A (ko) 2009-11-19
US20110165139A1 (en) 2011-07-07
EP2133090A4 (en) 2012-02-01
JPWO2008111573A1 (ja) 2010-06-24
NZ579490A (en) 2012-04-27

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