WO2008120644A1 - アルコール連続生産方法 - Google Patents

アルコール連続生産方法 Download PDF

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Publication number
WO2008120644A1
WO2008120644A1 PCT/JP2008/055766 JP2008055766W WO2008120644A1 WO 2008120644 A1 WO2008120644 A1 WO 2008120644A1 JP 2008055766 W JP2008055766 W JP 2008055766W WO 2008120644 A1 WO2008120644 A1 WO 2008120644A1
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WO
WIPO (PCT)
Prior art keywords
alcohol
fermentation tank
fermentation
recycling
continuously producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/055766
Other languages
English (en)
French (fr)
Inventor
Masayuki Tohyama
Manabu Katagiri
Kazue Takaoka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Engineering and Shipbuilding Co Ltd
Original Assignee
Mitsui Engineering and Shipbuilding Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Engineering and Shipbuilding Co Ltd filed Critical Mitsui Engineering and Shipbuilding Co Ltd
Priority to BRPI0809534A priority Critical patent/BRPI0809534A2/pt
Priority to EP08738951.6A priority patent/EP2143802A4/en
Priority to JP2009507483A priority patent/JP5130288B2/ja
Publication of WO2008120644A1 publication Critical patent/WO2008120644A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/06—Ethanol, i.e. non-beverage
    • C12P7/14—Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C12N1/185—Saccharomyces isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/85—Saccharomyces
    • C12R2001/865—Saccharomyces cerevisiae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

【課題】菌体リサイクルを行うアルコール連続生産において、リサイクル率と、希釈率の最適な範囲を特定して、高いエタノール生産性を有する、アルコール連続生産方法を提供すること。 【解決手段】発酵槽内に凝集沈殿性を有する酵母を存在させ、発酵槽にアルコール原料を供給してアルコール発酵を行い、得られたアルコール培養液を前記発酵槽から引き抜いて、かつ前記引き抜いた液中の酵母菌体は回収し前記発酵槽内に返送する菌体リサイクルをしながらアルコール発酵を行う際に、前記発酵槽下方に強制的な液流を発生させてアルコールを生産するアルコール連続生産方法であって、菌体のリサイクル比（ｒ）を０＜ｒ＜０．４とし、希釈率Ｄ（ｈ-１）が０．２≦Ｄ≦０．３とする条件で行われているときに、アルコール生産性（ｇ／Ｌ・ｈ）が１５ｇ／Ｌｈ以上となることを特徴とする。
PCT/JP2008/055766 2007-03-30 2008-03-26 アルコール連続生産方法 Ceased WO2008120644A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BRPI0809534A BRPI0809534A2 (pt) 2007-03-30 2008-03-26 método para produção contínua de álcool
EP08738951.6A EP2143802A4 (en) 2007-03-30 2008-03-26 PROCESS FOR CONTINUOUS ALCOHOL PRODUCTION
JP2009507483A JP5130288B2 (ja) 2007-03-30 2008-03-26 アルコール連続生産方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-095728 2007-03-30
JP2007095728 2007-03-30

Publications (1)

Publication Number Publication Date
WO2008120644A1 true WO2008120644A1 (ja) 2008-10-09

Family

ID=39808226

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/055766 Ceased WO2008120644A1 (ja) 2007-03-30 2008-03-26 アルコール連続生産方法

Country Status (4)

Country Link
EP (1) EP2143802A4 (ja)
JP (1) JP5130288B2 (ja)
BR (1) BRPI0809534A2 (ja)
WO (1) WO2008120644A1 (ja)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011036146A (ja) * 2009-08-07 2011-02-24 Toray Ind Inc 連続培養による化学品の製造方法および製造装置
KR101416744B1 (ko) * 2011-10-27 2014-07-09 대우조선해양 주식회사 연속 발효 장치 및 이를 이용한 다단계 연속 발효 공정
JP2016086707A (ja) * 2014-10-31 2016-05-23 トヨタ自動車株式会社 連続培養によるエタノールの製造方法及び連続培養装置
CN109790560A (zh) * 2016-06-22 2019-05-21 合利菲姆有限公司 生产及分离脂质的方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106244633B (zh) * 2016-08-23 2019-06-18 广东省生物工程研究所（广州甘蔗糖业研究所） 一种酵母絮凝的可逆调控方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59135896A (ja) 1982-12-17 1984-08-04 Mitsui Eng & Shipbuild Co Ltd アルコ−ルの発酵生産法
JPH06284891A (ja) 1993-04-01 1994-10-11 Tsuushiyousangiyoushiyou Kiso Sangyo Kyokucho 凝集性微生物をリサイクルするアルコールの連続生産方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59135896A (ja) 1982-12-17 1984-08-04 Mitsui Eng & Shipbuild Co Ltd アルコ−ルの発酵生産法
JPH06284891A (ja) 1993-04-01 1994-10-11 Tsuushiyousangiyoushiyou Kiso Sangyo Kyokucho 凝集性微生物をリサイクルするアルコールの連続生産方法

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
GIJUTSU KAIHATSU HONBU: "Shin Kobo ni yoru Ethanol Hakko Gijutsu", MITSUI ZOSEN TECHNICAL REVIEW, no. 128, 1986, pages 42 - 47, XP008121151 *
KURIYAMA H. ET AL.: "Control of yeast flocculation activity in continuous ethanol fermentation", J. CHEM. ENG. JAPAN, vol. 26, no. 4, 1993, pages 429 - 431, XP000396509 *
NISHIDA R.: "Saibo Yugokabu Hakko Ethanol Hakko Tokusei", KAGAKU KEIZAI, vol. 32, no. 8, 1985, pages 26 - 32, XP008121150 *
OLIVEIRA S. ETAL.: "Continuous ethanol fermentation in a tower reactor with flocculating yeast recycle: scale-up effects on process performance, kinetic parameters and model predictions", BIOPROCESS ENGINEERING, vol. 20, no. 6, 1999, pages 525 - 530, XP008121152 *
PAIVA T. ET AL.: "Continuous alcoholic fermentation process in a tower reactor with recycling of flocculating yeast", APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, vol. 57/58, 1996, pages 535 - 541, XP008121541 *
See also references of EP2143802A4 *
TOYAMA M. AND TAKAOKA: "Gishusei Kobo o Mochiita Biomass Genryo kara no Renzokushiki Ethanol Hakko Process no Kaihatsu", MITSUI ZOSEN TECHNICAL REVIEW, no. 192, November 2007 (2007-11-01), pages 1 - 7, XP008121533 *
WIECZOREK A. AND MICHALSKI H.: "Continuous ethanol production by flocculating yeast in the fluidized bed bioreactor", FEMS MICROBIOLOGY REVIEWS, vol. 14, no. 1, 1994, pages 69 - 74, XP023708147 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011036146A (ja) * 2009-08-07 2011-02-24 Toray Ind Inc 連続培養による化学品の製造方法および製造装置
KR101416744B1 (ko) * 2011-10-27 2014-07-09 대우조선해양 주식회사 연속 발효 장치 및 이를 이용한 다단계 연속 발효 공정
US9920290B2 (en) 2011-10-27 2018-03-20 Biol Systems Co., Ltd. Continuous fermentation apparatus and multi-step continuous fermentation process using the same
JP2016086707A (ja) * 2014-10-31 2016-05-23 トヨタ自動車株式会社 連続培養によるエタノールの製造方法及び連続培養装置
US10308908B2 (en) 2014-10-31 2019-06-04 Toyota Jidosha Kabushiki Kaisha Method of producing ethanol using continuous culture and continuous culture apparatus
CN109790560A (zh) * 2016-06-22 2019-05-21 合利菲姆有限公司 生产及分离脂质的方法
JP2019522492A (ja) * 2016-06-22 2019-08-15 ホリフェルム リミテッド 脂質を製造及び分離する方法
JP6991207B2 (ja) 2016-06-22 2022-01-12 ホリフェルム リミテッド 脂質を製造及び分離する方法
CN109790560B (zh) * 2016-06-22 2022-12-09 合利菲姆有限公司 生产及分离脂质的方法

Also Published As

Publication number Publication date
EP2143802A4 (en) 2013-06-19
BRPI0809534A2 (pt) 2016-06-28
EP2143802A1 (en) 2010-01-13
JPWO2008120644A1 (ja) 2010-07-15
JP5130288B2 (ja) 2013-01-30

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