WO2009042070A3 - Production of isoprenoids - Google Patents

Production of isoprenoids Download PDF

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Publication number
WO2009042070A3
WO2009042070A3 PCT/US2008/010886 US2008010886W WO2009042070A3 WO 2009042070 A3 WO2009042070 A3 WO 2009042070A3 US 2008010886 W US2008010886 W US 2008010886W WO 2009042070 A3 WO2009042070 A3 WO 2009042070A3
Authority
WO
WIPO (PCT)
Prior art keywords
isoprenoids
methods
production
host cells
genetically modified
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/010886
Other languages
French (fr)
Other versions
WO2009042070A2 (en
Inventor
Hiroko Tsuruta
Jacob R Lenihan
Rika Regentin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amyris Inc
Original Assignee
Amyris Biotechnologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40239603&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2009042070(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to DK08832899.2T priority Critical patent/DK2217711T4/en
Priority to AU2008305655A priority patent/AU2008305655B2/en
Priority to JP2010525833A priority patent/JP2010539902A/en
Priority to EP08832899.2A priority patent/EP2217711B2/en
Priority to BRPI0816951-9A priority patent/BRPI0816951B1/en
Application filed by Amyris Biotechnologies Inc filed Critical Amyris Biotechnologies Inc
Priority to MX2010002990A priority patent/MX302107B/en
Priority to CN200880117160A priority patent/CN101868532A/en
Priority to CA2700211A priority patent/CA2700211C/en
Publication of WO2009042070A2 publication Critical patent/WO2009042070A2/en
Publication of WO2009042070A3 publication Critical patent/WO2009042070A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/32—Processes using, or culture media containing, lower alkanols, i.e. C1 to C6
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Provided herein are methods for a robust production of isoprenoids via one or more biosynthetic pathways. Also provided herein are nucleic acids, enzymes, expression vectors, and genetically modified host cells for carrying out the subject methods. Also provided herein are fermentation methods for high productivity of isoprenoids from genetically modified host cells.
PCT/US2008/010886 2007-09-20 2008-09-19 Production of isoprenoids Ceased WO2009042070A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CA2700211A CA2700211C (en) 2007-09-20 2008-09-19 Production of isoprenoids
AU2008305655A AU2008305655B2 (en) 2007-09-20 2008-09-19 Production of isoprenoids
JP2010525833A JP2010539902A (en) 2007-09-20 2008-09-19 Production of isoprenoids
EP08832899.2A EP2217711B2 (en) 2007-09-20 2008-09-19 Production of isoprenoids
BRPI0816951-9A BRPI0816951B1 (en) 2007-09-20 2008-09-19 METHOD FOR PRODUCING AN ISOPRENOID COMPOUND
DK08832899.2T DK2217711T4 (en) 2007-09-20 2008-09-19 PRODUCTION OF ISOPRENOIDS
MX2010002990A MX302107B (en) 2007-09-20 2008-09-19 Production of isoprenoids.
CN200880117160A CN101868532A (en) 2007-09-20 2008-09-19 Preparation of isoprenoids

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99479007P 2007-09-20 2007-09-20
US60/994,790 2007-09-20
US4935008P 2008-04-30 2008-04-30
US61/049,350 2008-04-30

Publications (2)

Publication Number Publication Date
WO2009042070A2 WO2009042070A2 (en) 2009-04-02
WO2009042070A3 true WO2009042070A3 (en) 2009-08-13

Family

ID=40239603

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/010886 Ceased WO2009042070A2 (en) 2007-09-20 2008-09-19 Production of isoprenoids

Country Status (11)

Country Link
US (3) US11725225B2 (en)
EP (1) EP2217711B2 (en)
JP (1) JP2010539902A (en)
CN (1) CN101868532A (en)
AU (1) AU2008305655B2 (en)
BR (1) BRPI0816951B1 (en)
CA (2) CA3044405C (en)
DK (1) DK2217711T4 (en)
MX (1) MX302107B (en)
WO (1) WO2009042070A2 (en)
ZA (1) ZA201002000B (en)

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DK2438156T3 (en) 2009-06-01 2014-05-26 Amyris Inc PROCEDURE FOR MANUFACTURING A GENETICALLY MODIFIED MICROBE
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WO2011146833A1 (en) * 2010-05-20 2011-11-24 Evolva Inc. Method of producing isoprenoid compounds in yeast
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JP2014504497A (en) 2010-12-22 2014-02-24 ダニスコ・ユーエス・インク Compositions and methods for improving isoprene production using two ISPG enzymes
EP2655597A1 (en) 2010-12-22 2013-10-30 Danisco US Inc. Biological production of pentose sugars using recombinant cells
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AU2012211052A1 (en) * 2011-01-28 2013-09-05 Amyris, Inc. Gel-encapsulated microcolony screening
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BR112013028544B1 (en) * 2011-05-09 2020-10-27 Amyris, Inc method for producing a heterologous acetylcholine-derived compound
BR112013027954A2 (en) * 2011-05-13 2017-01-17 Amyris Inc methods and compositions for detecting microbial production of water immiscible compounds
EP2537926A1 (en) 2011-06-21 2012-12-26 Isobionics B.V. Valencene synthase
LT2748084T (en) 2011-08-24 2019-08-26 APG Polytech, LLC Articles containing oxygen-scavenging materials
WO2013028307A1 (en) 2011-08-24 2013-02-28 Amyris, Inc. Derivatives of hydrocarbon terpenes
BR112014008278A2 (en) * 2011-10-07 2017-04-18 Danisco Us Inc use of phosphocetolase in the production of mevalonate, isoprenoid and isoprene precursors
MX362264B (en) * 2012-02-22 2019-01-10 Amyris Inc Polymerization of compositions comprising a farnesene.
US9012385B2 (en) 2012-02-29 2015-04-21 Elevance Renewable Sciences, Inc. Terpene derived compounds
US8741612B2 (en) 2012-05-16 2014-06-03 Glycos Biotechnologies, Inc. Microorganisms and processes for the production of isoprene
US20130323820A1 (en) 2012-06-01 2013-12-05 Lanzatech New Zealand Limited Recombinant microorganisms and uses therefor
BR112015001155A2 (en) 2012-07-18 2017-06-27 Isobionics B V rhodobacter host cell respective use and method for preparing monoterpene or sesquiterpene
JP2014076042A (en) * 2012-09-21 2014-05-01 Sekisui Chem Co Ltd RECOMBINANT CELLS AND PRODUCTION METHOD OF β-PHELLANDRENE
US20150057204A1 (en) 2013-03-12 2015-02-26 Elevance Renewable Sciences, Inc. Maleanized Ester Derivatives
US20140274832A1 (en) 2013-03-12 2014-09-18 Elevance Renewable Sciences, Inc. Maleinized ester derivatives
CN104120148A (en) * 2013-04-28 2014-10-29 中国科学院青岛生物能源与过程研究所 Method for synthesizing alpha-pinene or beta-pinene by adopting biological process
EP3017050B1 (en) 2013-07-04 2020-09-09 Isobionics B.V. Two-phase fermentation process for the production of an isoprenoid
AU2013397496B2 (en) * 2013-08-07 2020-03-12 Amyris, Inc. Methods for stabilizing production of acetyl-coenzyme a derived compounds
EP3130672B1 (en) 2014-04-09 2025-09-24 Adeka Corporation Mutant enzyme and production method for terpenoid using said mutant enzyme
CA3003163A1 (en) 2015-10-29 2017-05-04 Senomyx, Inc. High intensity sweeteners
EP3478844A4 (en) * 2016-07-01 2020-04-08 International Flavors & Fragrances Inc. Compositions and methods for producing citrus terpenoids
CN106011178B (en) * 2016-07-14 2019-02-26 珀莱雅化妆品股份有限公司 A kind of method that utilizes sugar sorghum stalk and sugarcane waste bagasse to ferment and prepare β-farnesene
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BR112019023104A2 (en) 2017-05-03 2020-11-03 Firmenich Incorporated methods for making high intensity sweetener
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CN110468089B (en) * 2018-05-09 2023-07-11 深圳艾格鑫科技有限公司 Microorganism and use thereof
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Also Published As

Publication number Publication date
CA2700211C (en) 2019-07-30
AU2008305655B2 (en) 2013-10-31
US11725225B2 (en) 2023-08-15
AU2008305655A1 (en) 2009-04-02
CN101868532A (en) 2010-10-20
EP2217711B1 (en) 2015-08-26
JP2010539902A (en) 2010-12-24
US20090137014A1 (en) 2009-05-28
CA3044405A1 (en) 2009-04-02
WO2009042070A2 (en) 2009-04-02
MX2010002990A (en) 2010-04-30
CA2700211A1 (en) 2009-04-02
BRPI0816951A2 (en) 2014-10-14
EP2217711A2 (en) 2010-08-18
DK2217711T4 (en) 2025-06-02
ZA201002000B (en) 2011-05-25
DK2217711T3 (en) 2015-09-14
US20240035061A1 (en) 2024-02-01
EP2217711B2 (en) 2025-04-23
BRPI0816951B1 (en) 2023-01-17
CA3044405C (en) 2021-10-19
US12146176B2 (en) 2024-11-19
MX302107B (en) 2012-08-08
US20250122551A1 (en) 2025-04-17

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