WO2009055880A3 - New method for diagnosing sjogren's syndrome - Google Patents

New method for diagnosing sjogren's syndrome Download PDF

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Publication number
WO2009055880A3
WO2009055880A3 PCT/BE2008/000087 BE2008000087W WO2009055880A3 WO 2009055880 A3 WO2009055880 A3 WO 2009055880A3 BE 2008000087 W BE2008000087 W BE 2008000087W WO 2009055880 A3 WO2009055880 A3 WO 2009055880A3
Authority
WO
WIPO (PCT)
Prior art keywords
syndrome
new method
diagnosing
sjogren
diagnosing sjogren
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/BE2008/000087
Other languages
French (fr)
Other versions
WO2009055880A2 (en
Inventor
Xavier Bossuyt
Den Bergh Karolien Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Katholieke Universiteit Leuven
Original Assignee
Katholieke Universiteit Leuven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Katholieke Universiteit Leuven filed Critical Katholieke Universiteit Leuven
Priority to EP08845893A priority Critical patent/EP2235540A2/en
Publication of WO2009055880A2 publication Critical patent/WO2009055880A2/en
Publication of WO2009055880A3 publication Critical patent/WO2009055880A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875Nucleoproteins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders
    • G01N2800/101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Peptides Or Proteins (AREA)
  • Monitoring And Testing Of Nuclear Reactors (AREA)

Abstract

The present invention relates to a method of diagnosing Sjögren's syndrome. More particularly the present invention relates to methods and compositions for detecting anti-heterogeneous nuclear ribonucleoprotein-H1 (hnRNP-H1 ) autoantibodies for diagnosing Sjogren's syndrome.
PCT/BE2008/000087 2007-10-29 2008-10-29 New method for diagnosing sjogren's syndrome Ceased WO2009055880A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08845893A EP2235540A2 (en) 2007-10-29 2008-10-29 New method for diagnosing sjogren's syndrome

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0721160A GB0721160D0 (en) 2007-10-29 2007-10-29 New method for diagnosing sjogren's syndrome
GB0721160.0 2007-10-29

Publications (2)

Publication Number Publication Date
WO2009055880A2 WO2009055880A2 (en) 2009-05-07
WO2009055880A3 true WO2009055880A3 (en) 2009-06-04

Family

ID=38830103

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/BE2008/000087 Ceased WO2009055880A2 (en) 2007-10-29 2008-10-29 New method for diagnosing sjogren's syndrome

Country Status (3)

Country Link
EP (1) EP2235540A2 (en)
GB (1) GB0721160D0 (en)
WO (1) WO2009055880A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2936060B1 (en) * 2008-09-17 2010-11-19 Assist Publ Hopitaux De Paris METHOD FOR DIAGNOSING SYSTEMIC SCLERODERMY OR PULMONARY ARTERIAL HYPERTENSION
GB0915332D0 (en) 2009-09-02 2009-10-07 Univ Leuven Kath New methods for diagnosing autoimmune diseases
GB2622246A (en) * 2022-09-08 2024-03-13 Oncimmune Germany Gmbh Antibody assay
CN121476595B (en) * 2026-01-07 2026-04-10 北京大学人民医院 Application of anti-PCCB antibody in preparation of Sjogren syndrome diagnosis product

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002033415A2 (en) * 2000-10-17 2002-04-25 Bio-Rad Laboratories, Inc. Pattern recognition method for diagnosis of systemic autoimmune diseases
WO2005116652A2 (en) * 2004-04-16 2005-12-08 Vanderbilt University Method for in vitro diagnosis of sjörgen’s syndrome and lupus

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002033415A2 (en) * 2000-10-17 2002-04-25 Bio-Rad Laboratories, Inc. Pattern recognition method for diagnosis of systemic autoimmune diseases
WO2005116652A2 (en) * 2004-04-16 2005-12-08 Vanderbilt University Method for in vitro diagnosis of sjörgen’s syndrome and lupus

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BENITO-GARCIA ELIZABETH ET AL: "Guidelines for immunologic laboratory testing in the rheumatic diseases: anti-Sm and anti-RNP antibody tests.", ARTHRITIS AND RHEUMATISM 15 DEC 2004, vol. 51, no. 6, 15 December 2004 (2004-12-15), pages 1030 - 1044, XP002522109, ISSN: 0004-3591 *
FIJAK MONIKA ET AL: "Identification of immunodominant autoantigens in rat autoimmune orchitis", JOURNAL OF PATHOLOGY, vol. 207, no. 2, October 2005 (2005-10-01), pages 127 - 138, XP002522108, ISSN: 0022-3417 *
LUYCKX ARIANE ET AL: "Clinical relevance of measurement of antibodies to individual snU1-RNP proteins.", CLINICAL CHEMISTRY OCT 2005, vol. 51, no. 10, October 2005 (2005-10-01), pages 1888 - 1890, XP002522110, ISSN: 0009-9147 *
SKRINER K ET AL: "Anti-A2/RA33 autoantibodies are directed to the RNA binding region of the A2 protein of the heterogeneous nuclear ribonucleoprotein complex. Differential epitope recognition in rheumatoid arthritis, systemic lupus erythematosus, and mixed connective tissue disease.", THE JOURNAL OF CLINICAL INVESTIGATION 1 JUL 1997, vol. 100, no. 1, 1 July 1997 (1997-07-01), pages 127 - 135, XP002522111, ISSN: 0021-9738 *

Also Published As

Publication number Publication date
WO2009055880A2 (en) 2009-05-07
GB0721160D0 (en) 2007-12-05
EP2235540A2 (en) 2010-10-06

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