WO2009063991A1 - ピリドオキサゼピン誘導体およびその用途 - Google Patents

ピリドオキサゼピン誘導体およびその用途 Download PDF

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Publication number
WO2009063991A1
WO2009063991A1 PCT/JP2008/070808 JP2008070808W WO2009063991A1 WO 2009063991 A1 WO2009063991 A1 WO 2009063991A1 JP 2008070808 W JP2008070808 W JP 2008070808W WO 2009063991 A1 WO2009063991 A1 WO 2009063991A1
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Prior art keywords
pyridooxazepine
derivative
optionally substituted
compound represented
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
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PCT/JP2008/070808
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English (en)
French (fr)
Inventor
Takahiro Matsumoto
Tomokazu Kusumoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
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Takeda Pharmaceutical Co Ltd
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Application filed by Takeda Pharmaceutical Co Ltd filed Critical Takeda Pharmaceutical Co Ltd
Priority to EP08849982.7A priority Critical patent/EP2213675B1/en
Priority to JP2009541193A priority patent/JP5361733B2/ja
Priority to US12/742,837 priority patent/US8329687B2/en
Publication of WO2009063991A1 publication Critical patent/WO2009063991A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Abstract

　本発明は、優れたセロトニン５－ＨＴ２Ｃ受容体活性化作用を有する下式化合物を提供する： 式  〔式中、Ａは、－ＯＲ１または－Ｓ（Ｏ）ｐＲ２を示し、Ｒ１およびＲ２は、それぞれ水素原子、置換基を有していてもよい炭化水素基、または置換基を有していてもよい複素環基を示し、ｐは０、１または２を示す。〕で表される化合物またはその塩。
PCT/JP2008/070808 2007-11-15 2008-11-14 ピリドオキサゼピン誘導体およびその用途 Ceased WO2009063991A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08849982.7A EP2213675B1 (en) 2007-11-15 2008-11-14 Pyridooxazepine derivative and use thereof
JP2009541193A JP5361733B2 (ja) 2007-11-15 2008-11-14 ピリドオキサゼピン誘導体およびその用途
US12/742,837 US8329687B2 (en) 2007-11-15 2008-11-14 Pyridooxazepine derivative and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007297169 2007-11-15
JP2007-297169 2007-11-15

Publications (1)

Publication Number Publication Date
WO2009063991A1 true WO2009063991A1 (ja) 2009-05-22

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Application Number Title Priority Date Filing Date
PCT/JP2008/070808 Ceased WO2009063991A1 (ja) 2007-11-15 2008-11-14 ピリドオキサゼピン誘導体およびその用途

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Country Link
US (1) US8329687B2 (ja)
EP (1) EP2213675B1 (ja)
JP (1) JP5361733B2 (ja)
WO (1) WO2009063991A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010147226A1 (en) * 2009-06-15 2010-12-23 Takeda Pharmaceutical Company Limited Pyrazinooxazepine derivatives
US8916549B2 (en) 2009-08-04 2014-12-23 Takeda Pharmaceutical Company Limited Thienooxazepine derivative
WO2015066344A1 (en) 2013-11-01 2015-05-07 Arena Pharmaceuticals, Inc. 5-ht2c receptor agonists and compositions and methods of use
CN105441958A (zh) * 2015-11-27 2016-03-30 重庆大学 含两个苯并三氮唑环的缓蚀剂的合成与应用
WO2017026538A1 (en) 2015-08-07 2017-02-16 Takeda Pharmaceutical Company Limited Production method of pyrazine

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