WO2009071219A3 - Oral dispersable tablet - Google Patents

Oral dispersable tablet Download PDF

Info

Publication number
WO2009071219A3
WO2009071219A3 PCT/EP2008/009968 EP2008009968W WO2009071219A3 WO 2009071219 A3 WO2009071219 A3 WO 2009071219A3 EP 2008009968 W EP2008009968 W EP 2008009968W WO 2009071219 A3 WO2009071219 A3 WO 2009071219A3
Authority
WO
WIPO (PCT)
Prior art keywords
tablet
oral
dispersable tablet
oral dispersable
amount
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/009968
Other languages
French (fr)
Other versions
WO2009071219A2 (en
Inventor
Tobias Laich
Thomas Steenpass
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Schering Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma AG filed Critical Bayer Schering Pharma AG
Priority to JP2010536354A priority Critical patent/JP2011506279A/en
Priority to EP08856436A priority patent/EP2231126A2/en
Priority to CN2008801194609A priority patent/CN101888834A/en
Priority to MX2010005175A priority patent/MX2010005175A/en
Priority to BRPI0820861-1A priority patent/BRPI0820861A2/en
Publication of WO2009071219A2 publication Critical patent/WO2009071219A2/en
Publication of WO2009071219A3 publication Critical patent/WO2009071219A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention is directed to an oral disintegratable tablet which exhibits oral disintegratability of not more than 60 seconds. The tablet for oral administration, comprises an effective amount of at least one active agent, an amount of at least 50% (w/w) of a water insoluble parts, a surfactant and a disintegrant, such that said tablet is orally disintegretable or dispersable.
PCT/EP2008/009968 2007-12-08 2008-11-25 Oral dispersable tablet Ceased WO2009071219A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2010536354A JP2011506279A (en) 2007-12-08 2008-11-25 Orally dispersible tablets
EP08856436A EP2231126A2 (en) 2007-12-08 2008-11-25 Oral dispersable tablet
CN2008801194609A CN101888834A (en) 2007-12-08 2008-11-25 Orodispersible Tablets
MX2010005175A MX2010005175A (en) 2007-12-08 2008-11-25 Oral dispersable tablet.
BRPI0820861-1A BRPI0820861A2 (en) 2007-12-08 2008-11-25 Dispersible oral tablet

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07023802.7 2007-12-08
EP07023802 2007-12-08

Publications (2)

Publication Number Publication Date
WO2009071219A2 WO2009071219A2 (en) 2009-06-11
WO2009071219A3 true WO2009071219A3 (en) 2009-09-11

Family

ID=40631079

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/009968 Ceased WO2009071219A2 (en) 2007-12-08 2008-11-25 Oral dispersable tablet

Country Status (9)

Country Link
EP (1) EP2231126A2 (en)
JP (2) JP2011506279A (en)
KR (1) KR20100096140A (en)
CN (1) CN101888834A (en)
BR (1) BRPI0820861A2 (en)
MX (1) MX2010005175A (en)
RU (1) RU2010128019A (en)
TW (1) TW200938233A (en)
WO (1) WO2009071219A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120156293A1 (en) * 2009-09-08 2012-06-21 Hideaki Kitajima Antacid and laxative tablet
CN101797236B (en) * 2010-03-23 2012-05-23 西南大学 Rivastigmine orally disintegration tablet and preparation method thereof
PH12012502139A1 (en) * 2010-04-27 2022-03-21 Bayer Ip Gmbh Orally disintegrating tablet containing acarbose
US20110300216A1 (en) * 2010-06-03 2011-12-08 First Eric R Chewable, swallowable and effervescent solid dosage form for oral delivery of pharmaceutical actives
JP5750856B2 (en) * 2010-10-04 2015-07-22 ライオン株式会社 Solid pharmaceutical composition and pharmaceutical preparation
KR101237646B1 (en) * 2010-12-09 2013-03-04 주식회사 드림파마 Solid dispersion comprising celecoxib with improved bioavailibity, pharmaceutical composition comprising the solid dispersion, and preparation method of the solid dispersion
FR2968995B1 (en) * 2010-12-16 2013-03-22 Sanofi Aventis PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION TO PREVENT MEASUREMENT
FR2968992B1 (en) * 2010-12-16 2013-02-08 Sanofi Aventis ORODISPERSIBLE PHARMACEUTICAL TABLET BASED ON ZOLPIDEM
TR201100150A2 (en) * 2011-01-06 2012-07-23 Bi̇lgi̇ç Mahmut Water soluble dosage forms
WO2013115741A1 (en) * 2012-01-31 2013-08-08 Mahmut Bilgic Pharmaceutical compositions comprising alpha-glucosidase inhibitor
CN102600149B (en) * 2012-02-02 2013-12-04 西藏易明西雅生物医药科技有限公司 Pharmaceutical composition for treating diabetes
US20160136091A1 (en) 2013-07-19 2016-05-19 Sanwa Kagaku Kenkyusho Co., Ltd. Orally Disintegrating Tablet
EP3021837A1 (en) * 2013-07-19 2016-05-25 Bayer Pharma Aktiengesellschaft Super quick disintegrating tablet formula for api miglitol
CN103877041B (en) * 2014-03-14 2016-07-06 崔书豪 A kind of piroxicam dispersible tablet and preparation method thereof
CN115919894A (en) 2016-01-29 2023-04-07 株式会社Kit Solid preparation, preparation method of solid preparation and hydrogen evolution method
CN105640954B (en) * 2016-02-04 2019-03-05 青岛市海慈医疗集团 It is a kind of to treat dyspeptic Cisapride tablet
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
US11786471B2 (en) * 2016-07-11 2023-10-17 Wuhan Ll Science And Technology Development Co. Ltd. Complex disintegrant system for oral solid preparation and oral solid preparation comprising said complex disintegrant system
CN110191860A (en) 2016-08-23 2019-08-30 小林光 Formulation, its production method, and hydrogen supply method
CN110191699A (en) 2016-08-23 2019-08-30 小林光 Hydrogen supply material, method for producing the same, and method for supplying hydrogen
CN107334742B (en) * 2017-08-18 2020-01-31 山东力诺制药有限公司 fluoxetine hydrochloride dispersible tablet and preparation method thereof
WO2019066555A1 (en) * 2017-09-28 2019-04-04 Hanmi Pharm. Co., Ltd. Pharmaceutical composition including multi-unit spheroidal tablet containing esomeprazole and spheroidal pharmaceutically acceptable salt thereof, and method of preparing the pharmaceutical composition
CN110840850B (en) * 2018-07-24 2023-03-17 烟台药物研究所 Celecoxib freeze-dried orally disintegrating tablet with high bioavailability and preparation method thereof
CN109864971B (en) * 2019-04-08 2021-12-17 西安远大德天药业股份有限公司 Granules of lamotrigine solid dispersion and preparation method thereof
CN114224855B (en) * 2021-12-01 2023-11-28 北京悦康科创医药科技股份有限公司 Doxazosin mesylate buccal tablet and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802700A1 (en) * 1998-01-24 1999-07-29 Bayer Ag Preparation of fast-dissolving tablets for controlling blood sugar levels
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
WO2006043025A1 (en) * 2004-10-19 2006-04-27 Reckitt Benckiser Healthcare (Uk) Limited Granular compositions comprising solidified melt granules of a cox-2 selective inhibitor
US20070196474A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising calcium carbonate
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1688291A (en) * 2002-02-01 2005-10-26 辉瑞产品公司 Immediate release dosage forms containing solid drug dispersions
JP4739217B2 (en) * 2003-05-07 2011-08-03 サムヤン コーポレイション Highly plastic granules for making fast dissolving tablets
US7230016B2 (en) * 2003-05-13 2007-06-12 Synthon Ip Inc. Pioglitazone salts, such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19802700A1 (en) * 1998-01-24 1999-07-29 Bayer Ag Preparation of fast-dissolving tablets for controlling blood sugar levels
US20040265375A1 (en) * 2003-04-16 2004-12-30 Platteeuw Johannes J. Orally disintegrating tablets
US20070196474A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly disintegrating low friability tablets comprising calcium carbonate
US20070196477A1 (en) * 2004-04-30 2007-08-23 Withiam Michael C Rapidly dissolving tablets comprising low surface area calcium phosphates
WO2006043025A1 (en) * 2004-10-19 2006-04-27 Reckitt Benckiser Healthcare (Uk) Limited Granular compositions comprising solidified melt granules of a cox-2 selective inhibitor

Also Published As

Publication number Publication date
BRPI0820861A2 (en) 2015-06-16
MX2010005175A (en) 2010-08-02
JP2011506279A (en) 2011-03-03
WO2009071219A2 (en) 2009-06-11
TW200938233A (en) 2009-09-16
JP2015038123A (en) 2015-02-26
RU2010128019A (en) 2012-01-20
CN101888834A (en) 2010-11-17
EP2231126A2 (en) 2010-09-29
KR20100096140A (en) 2010-09-01

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