WO2009072657A1 - ナノ機能性シリカ粒子およびその製造方法 - Google Patents

ナノ機能性シリカ粒子およびその製造方法 Download PDF

Info

Publication number
WO2009072657A1
WO2009072657A1 PCT/JP2008/072285 JP2008072285W WO2009072657A1 WO 2009072657 A1 WO2009072657 A1 WO 2009072657A1 JP 2008072285 W JP2008072285 W JP 2008072285W WO 2009072657 A1 WO2009072657 A1 WO 2009072657A1
Authority
WO
WIPO (PCT)
Prior art keywords
nanofunctional
silica particles
mercaptopropyl
manufacturing
coating layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/072285
Other languages
English (en)
French (fr)
Inventor
Michihiro Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Tokushima NUC
Original Assignee
University of Tokushima NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Tokushima NUC filed Critical University of Tokushima NUC
Priority to EP08856953.8A priority Critical patent/EP2233437A4/en
Priority to US12/734,968 priority patent/US9265729B2/en
Priority to JP2009544771A priority patent/JP5709292B2/ja
Publication of WO2009072657A1 publication Critical patent/WO2009072657A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/06—Preparatory processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/22—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/28—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen sulfur-containing groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/20—Polysiloxanes containing silicon bound to unsaturated aliphatic groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/04—Polysiloxanes
    • C08G77/22—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen
    • C08G77/26—Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen and oxygen nitrogen-containing groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995—Silane, siloxane or silicone coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Silicon Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

【課題】 機能性と品質に優れ、しかも、低コストでの量産が可能なナノ機能性シリカ粒子を提供する。 【解決手段】 メルカプトプロピルトリメトキシシラン（ＭＰＳ）、メルカプトプロピルトリエトキシシラン（ＭＰＥＳ）、メルカプトプロピルメチルジメトキシシラン（ＭＰＤＭＳ）、トリメトキシ［２－（７－オキサビシクロ［４．１．０］－ヘプトー３－イル）エチル］シラン（ＥｐｏＰＳ）、チオシシアナトプロピルトリエトキシシラン（ＴＣＰＳ）およびアクリルオキシプロピルトリメトキシシラン（ＡＣＰＳ）からなる群より選択される１種または数種のシリカ化合物を含む被覆層と、前記被覆層内部に機能性粒子を含む、イメージングやアッセイ、診断、治療等、医療やバイオ研究等に利用される、ナノ機能性シリカ粒子が本発明によって提供される。  
PCT/JP2008/072285 2007-12-06 2008-12-08 ナノ機能性シリカ粒子およびその製造方法 Ceased WO2009072657A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP08856953.8A EP2233437A4 (en) 2007-12-06 2008-12-08 NANOFUNCTIONAL SILICON DIOXIDE PARTICLES AND MANUFACTURING METHOD THEREFOR
US12/734,968 US9265729B2 (en) 2007-12-06 2008-12-08 Nanofunctional silica particles and manufacturing method thereof
JP2009544771A JP5709292B2 (ja) 2007-12-06 2008-12-08 ナノ機能性シリカ粒子およびその製造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007316466 2007-12-06
JP2007-316466 2007-12-06

Publications (1)

Publication Number Publication Date
WO2009072657A1 true WO2009072657A1 (ja) 2009-06-11

Family

ID=40717834

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/072285 Ceased WO2009072657A1 (ja) 2007-12-06 2008-12-08 ナノ機能性シリカ粒子およびその製造方法

Country Status (4)

Country Link
US (1) US9265729B2 (ja)
EP (1) EP2233437A4 (ja)
JP (1) JP5709292B2 (ja)
WO (1) WO2009072657A1 (ja)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102192986A (zh) * 2010-03-19 2011-09-21 胡卫红 一种心肌肌钙蛋白i的检测试剂及其制备方法和用途
JP2011220705A (ja) * 2010-04-05 2011-11-04 Furukawa Electric Co Ltd:The イムノクロマトグラフィー用複合粒子
JP2011231200A (ja) * 2010-04-27 2011-11-17 Konica Minolta Medical & Graphic Inc 有機蛍光色素内包シリカナノ粒子、その製造方法、及びそれを用いた生体物質標識剤
JP2014153057A (ja) * 2013-02-04 2014-08-25 Furukawa Electric Co Ltd:The 標識抗体の製造方法
JP2016505475A (ja) * 2012-09-28 2016-02-25 ザ レジェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 超音波イメージング／治療のための分解性シリカナノシェル
JP2016105066A (ja) * 2014-12-01 2016-06-09 三洋化成工業株式会社 磁性シリカ粒子、該磁性シリカ粒子を用いた測定対象物質測定方法及び測定対象物質測定用試薬
JP2017527554A (ja) * 2014-08-19 2017-09-21 ノースウェスタン ユニバーシティ タンパク質／オリゴヌクレオチドコアシェルナノ粒子治療薬
JP2019123722A (ja) * 2010-08-27 2019-07-25 シエナ バイオファーマシューティカルズ，インク．Ｓｉｅｎｎａ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 標的とされた熱変調のための組成物及び方法
US10837018B2 (en) 2013-07-25 2020-11-17 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
CN112158851A (zh) * 2020-09-30 2021-01-01 武汉工程大学 一种异硫氰基功能化的二氧化硅材料的制备方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5311340B2 (ja) * 2006-06-08 2013-10-09 国立大学法人徳島大学 新規なナノシリカ粒子の製造方法と用途
US20100233270A1 (en) 2009-01-08 2010-09-16 Northwestern University Delivery of Oligonucleotide-Functionalized Nanoparticles
WO2012118829A2 (en) * 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
EP2785444A4 (en) * 2011-12-01 2015-08-19 Innovations Materium SILICA MICRO-CAPSULES, METHOD FOR THEIR PRODUCTION AND USE
US11213593B2 (en) 2014-11-21 2022-01-04 Northwestern University Sequence-specific cellular uptake of spherical nucleic acid nanoparticle conjugates
GB2552704A (en) * 2016-08-04 2018-02-07 Univ Bath Biomolecule preservation
US11364304B2 (en) 2016-08-25 2022-06-21 Northwestern University Crosslinked micellar spherical nucleic acids
WO2018209270A1 (en) 2017-05-11 2018-11-15 Northwestern University Adoptive cell therapy using spherical nucleic acids (snas)
US11964874B2 (en) 2020-06-09 2024-04-23 Agilent Technologies, Inc. Etched non-porous particles and method of producing thereof
CN115595146A (zh) * 2022-12-15 2023-01-13 中国人民解放军军事科学院军事医学研究院（Cn） 一种比色荧光双信号纳米微球及其制备方法与应用
CN118906156B (zh) * 2024-09-10 2025-06-06 广东兆盈合成新材有限公司 一种人造板可再生成型板材及其制备方法
CN120230490B (zh) * 2025-05-14 2025-09-19 广东格林诺实业有限公司 一种家具用带胶封边条及其制备方法

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001520937A (ja) * 1997-10-28 2001-11-06 ザ・ユニヴァシティ・オブ・メルボルン 安定化粒子、その製造方法、およびその用途
WO2003002633A1 (en) 2001-06-29 2003-01-09 Nanomics Biosystems Pty, Ltd. Synthesis and use of organosilica particles
WO2003060037A1 (fr) * 2001-12-27 2003-07-24 Techno Network Shikoku Co., Ltd. Spheres de silice contenant des molecules de colorant fluorescent
JP2003253154A (ja) * 2001-12-25 2003-09-10 Asahi Kasei Corp 無機多孔性微粒子
JP2003270154A (ja) * 2001-12-27 2003-09-25 Techno Network Shikoku Co Ltd 蛍光色素分子含有シリカ球
JP2005538033A (ja) * 2001-12-04 2005-12-15 ナノスペクトラ バイオサイエンセズ，インク． 過剰なあるいは不適切な新脈管形成によって特徴付けられる病状の治療
JP2006160107A (ja) 2004-12-08 2006-06-22 Sumitomo Rubber Ind Ltd 空気入りタイヤ
WO2006070582A1 (ja) 2004-12-09 2006-07-06 Techno Network Shikoku. Co., Ltd. 標識分子含有シリカ球の調製方法
WO2007074722A1 (ja) * 2005-12-27 2007-07-05 The Furukawa Electric Co., Ltd. 蛍光ナノシリカ粒子、ナノ蛍光材料、それを用いたバイオチップ及びそのアッセイ法
WO2007097377A1 (ja) * 2006-02-24 2007-08-30 The Furukawa Electric Co., Ltd. フローサイトメトリーによる生体分子の定量システム、その定量方法、細胞の検出・分取システム、その検出・分取方法、それらに用いる蛍光シリカ粒子、及び複数個の蛍光シリカ粒子を組み合わせたキット
WO2007142316A1 (ja) * 2006-06-08 2007-12-13 The University Of Tokushima 新規なナノシリカ粒子の製造方法と用途
JP2008308371A (ja) * 2007-06-15 2008-12-25 Hokkaido Univ 異方形状粒子および該粒子の製造方法
JP2008311141A (ja) * 2007-06-15 2008-12-25 Jgc Catalysts & Chemicals Ltd 導電性粒子の製造方法および導電性粒子

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3616133A1 (de) * 1985-09-25 1987-11-19 Merck Patent Gmbh Kugelfoermige sio(pfeil abwaerts)2(pfeil abwaerts)-partikel
JPH10160737A (ja) * 1996-12-03 1998-06-19 Dainippon Printing Co Ltd 光学的分析装置用測定チップ及びその製造方法
ES2584553T3 (es) * 1999-10-06 2016-09-28 Becton Dickinson And Company Nanopartículas compuestas espectroscópicamente activas superficialmente potenciadas
US20040101822A1 (en) * 2002-11-26 2004-05-27 Ulrich Wiesner Fluorescent silica-based nanoparticles
DE102004011110A1 (de) * 2004-03-08 2005-09-22 Merck Patent Gmbh Verfahren zur Herstellung monodisperser SiO2-Partikel
US7534489B2 (en) * 2004-09-24 2009-05-19 Agency For Science, Technology And Research Coated composites of magnetic material and quantum dots
JP5855827B2 (ja) * 2007-06-06 2016-02-09 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 表面増強ラマン散乱レポーターとしての近赤外色素

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001520937A (ja) * 1997-10-28 2001-11-06 ザ・ユニヴァシティ・オブ・メルボルン 安定化粒子、その製造方法、およびその用途
WO2003002633A1 (en) 2001-06-29 2003-01-09 Nanomics Biosystems Pty, Ltd. Synthesis and use of organosilica particles
JP2005538033A (ja) * 2001-12-04 2005-12-15 ナノスペクトラ バイオサイエンセズ，インク． 過剰なあるいは不適切な新脈管形成によって特徴付けられる病状の治療
JP2003253154A (ja) * 2001-12-25 2003-09-10 Asahi Kasei Corp 無機多孔性微粒子
WO2003060037A1 (fr) * 2001-12-27 2003-07-24 Techno Network Shikoku Co., Ltd. Spheres de silice contenant des molecules de colorant fluorescent
JP2003270154A (ja) * 2001-12-27 2003-09-25 Techno Network Shikoku Co Ltd 蛍光色素分子含有シリカ球
JP2006160107A (ja) 2004-12-08 2006-06-22 Sumitomo Rubber Ind Ltd 空気入りタイヤ
WO2006070582A1 (ja) 2004-12-09 2006-07-06 Techno Network Shikoku. Co., Ltd. 標識分子含有シリカ球の調製方法
WO2007074722A1 (ja) * 2005-12-27 2007-07-05 The Furukawa Electric Co., Ltd. 蛍光ナノシリカ粒子、ナノ蛍光材料、それを用いたバイオチップ及びそのアッセイ法
WO2007097377A1 (ja) * 2006-02-24 2007-08-30 The Furukawa Electric Co., Ltd. フローサイトメトリーによる生体分子の定量システム、その定量方法、細胞の検出・分取システム、その検出・分取方法、それらに用いる蛍光シリカ粒子、及び複数個の蛍光シリカ粒子を組み合わせたキット
JP2009014730A (ja) * 2006-02-24 2009-01-22 Furukawa Electric Co Ltd:The フローサイトメトリーによる生体分子の定量又は細胞の検出・分取に用いる蛍光シリカ粒子、及び複数個の蛍光シリカ粒子を組み合わせたキット
JP2009014729A (ja) * 2006-02-24 2009-01-22 Furukawa Electric Co Ltd:The フローサイトメトリーによる細胞の検出・分取システム、及び検出・分取方法
WO2007142316A1 (ja) * 2006-06-08 2007-12-13 The University Of Tokushima 新規なナノシリカ粒子の製造方法と用途
JP2008308371A (ja) * 2007-06-15 2008-12-25 Hokkaido Univ 異方形状粒子および該粒子の製造方法
JP2008311141A (ja) * 2007-06-15 2008-12-25 Jgc Catalysts & Chemicals Ltd 導電性粒子の製造方法および導電性粒子

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 46, 2007, pages 3680 - 3682
JOURNAL OF AMERICA CHEMICAL SOCIETY, vol. 129, 2007, pages 8962 - 8963
See also references of EP2233437A4 *
STOBER, W.; FINK, A.; BOHN, E., J. COLLOID INTERFACE SCI., vol. 26, 1968, pages 62 - 69

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102192986A (zh) * 2010-03-19 2011-09-21 胡卫红 一种心肌肌钙蛋白i的检测试剂及其制备方法和用途
JP2011220705A (ja) * 2010-04-05 2011-11-04 Furukawa Electric Co Ltd:The イムノクロマトグラフィー用複合粒子
JP2011231200A (ja) * 2010-04-27 2011-11-17 Konica Minolta Medical & Graphic Inc 有機蛍光色素内包シリカナノ粒子、その製造方法、及びそれを用いた生体物質標識剤
JP2019123722A (ja) * 2010-08-27 2019-07-25 シエナ バイオファーマシューティカルズ，インク．Ｓｉｅｎｎａ Ｂｉｏｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 標的とされた熱変調のための組成物及び方法
JP2016505475A (ja) * 2012-09-28 2016-02-25 ザ レジェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 超音波イメージング／治療のための分解性シリカナノシェル
JP2014153057A (ja) * 2013-02-04 2014-08-25 Furukawa Electric Co Ltd:The 標識抗体の製造方法
US10837018B2 (en) 2013-07-25 2020-11-17 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
US10894963B2 (en) 2013-07-25 2021-01-19 Exicure, Inc. Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
JP2017527554A (ja) * 2014-08-19 2017-09-21 ノースウェスタン ユニバーシティ タンパク質／オリゴヌクレオチドコアシェルナノ粒子治療薬
US12264344B2 (en) 2014-08-19 2025-04-01 Northwestern University Protein/oligonucleotide core-shell nanoparticle therapeutics
JP2016105066A (ja) * 2014-12-01 2016-06-09 三洋化成工業株式会社 磁性シリカ粒子、該磁性シリカ粒子を用いた測定対象物質測定方法及び測定対象物質測定用試薬
CN112158851A (zh) * 2020-09-30 2021-01-01 武汉工程大学 一种异硫氰基功能化的二氧化硅材料的制备方法
CN112158851B (zh) * 2020-09-30 2023-03-03 武汉工程大学 一种异硫氰基功能化的二氧化硅材料的制备方法

Also Published As

Publication number Publication date
US20100310872A1 (en) 2010-12-09
JPWO2009072657A1 (ja) 2011-04-28
JP5709292B2 (ja) 2015-04-30
US9265729B2 (en) 2016-02-23
EP2233437A1 (en) 2010-09-29
EP2233437A4 (en) 2016-07-27

Similar Documents

Publication Publication Date Title
WO2010004225A3 (fr) Detecteurs nanoporeux de composes aromatiques monocycliques et autres polluants
WO2009129384A3 (en) Hydrophilic and hydrophobic silane surface modification of abrasive grains
PL2145986T3 (pl) Roztwór i sposób elektrochemicznego osadzania metalu na substracie
IL196009A0 (en) Oriented image coating on transparent substrate
WO2007020062A3 (de) Beschichtungsmassen enthaltend mit silanen modifizierte nanopartikel
EP2079084A4 (en) COATED PARTICLE AND MANUFACTURING METHOD, ANISOTROPIC CONDUCTIVE ADHESIVE COMPOSITION USING THE COATED PARTICLE, AND ANISOTROPIC CONDUCTIVE ADHESIVE FILM
EP2070107A4 (en) ANTI-REFLECTION IMAGING LAYER FOR MULTIPLE STRUCTURING PROCESS
WO2006050917A3 (de) Verfahren zur beschichtung von metallischen oberflächen mit einer wässrigen silan/silanol/siloxan/ polysiloxan enthaltenden zusammensetzung und diese zusammensetzung
PL1868798T3 (pl) Sposób przenoszenia powłoki na powierzchnię podłoża soczewki z najbardziej dokładną jakością optyczną
WO2008018981A3 (en) Silicone resin and silicone composition
WO2010017558A3 (en) Composite material compositions and methods
BR0312959A (pt) Receptor de filtro casado não paramétrico para sistemas de comunicação sem fio
US20080041105A1 (en) Method of surface modification for the reduction of trace component dissolution
ATE446332T1 (de) Zusammensetzung mit verbesserter haftung auf porösen substraten
WO2009127406A8 (de) Perlglanzpigmente auf basis von feinen und dünnen substraten
TWI368787B (en) Light-redirecting film containing optical modification layer
WO2007024375A3 (en) Forehearth concentrate and method for opalization of glass
EP1999220A4 (en) Edging process of lens using transparent coating layer for protecting lens
CN107406968A (zh) 具有抗菌能力的真空沉积用防水型纳米涂层剂及利用其的涂布方法
TW200724616A (en) Compositions containing a silanol functional polymer and related hydrophilic coating films
TWI367777B (en) Filter element with coating for surface filtration
WO2009051453A3 (en) Composite materials, composite film manufactured by using the same and method for manufacturing composite film
TWI339641B (en) Method for attaching film for glass substrate
EP2058419A4 (en) METHOD FOR SEPARATING A SURFACE LAYER OR DIAMOND GROWTH LAYER
CN117247288B (zh) 一种具有抗菌功能的陶瓷砖及其制备方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08856953

Country of ref document: EP

Kind code of ref document: A1

WWE Wipo information: entry into national phase

Ref document number: 2009544771

Country of ref document: JP

NENP Non-entry into the national phase

Ref country code: DE

REEP Request for entry into the european phase

Ref document number: 2008856953

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2008856953

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12734968

Country of ref document: US