WO2009134612A3 - Methods and compositions related to quantitative array based methylation analysis - Google Patents

Methods and compositions related to quantitative array based methylation analysis Download PDF

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Publication number
WO2009134612A3
WO2009134612A3 PCT/US2009/040378 US2009040378W WO2009134612A3 WO 2009134612 A3 WO2009134612 A3 WO 2009134612A3 US 2009040378 W US2009040378 W US 2009040378W WO 2009134612 A3 WO2009134612 A3 WO 2009134612A3
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WO
WIPO (PCT)
Prior art keywords
methods
array based
methylation analysis
compositions related
based methylation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/040378
Other languages
French (fr)
Other versions
WO2009134612A2 (en
Inventor
Alexander M. Chagovetz
Steven M. Blair
Randy L. Jensen
Bryan J. Lowder
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University of Utah Research Foundation Inc
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University of Utah Research Foundation Inc
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Filing date
Publication date
Application filed by University of Utah Research Foundation Inc filed Critical University of Utah Research Foundation Inc
Priority to EP09739414A priority Critical patent/EP2274445A2/en
Priority to US12/934,356 priority patent/US9518288B2/en
Publication of WO2009134612A2 publication Critical patent/WO2009134612A2/en
Publication of WO2009134612A3 publication Critical patent/WO2009134612A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B30/00—Methods of screening libraries
    • C40B30/04—Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

Disclosed are compositions and a method for detection of methylation based on quantitative arrays.
PCT/US2009/040378 2008-04-11 2009-04-13 Methods and compositions related to quantitative array based methylation analysis Ceased WO2009134612A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09739414A EP2274445A2 (en) 2008-04-11 2009-04-13 Methods and compositions related to quantitative array based methylation analysis
US12/934,356 US9518288B2 (en) 2008-04-11 2009-04-13 Methods and compositions related to quantitative, array based methylation analysis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4407508P 2008-04-11 2008-04-11
US61/044,075 2008-04-11

Publications (2)

Publication Number Publication Date
WO2009134612A2 WO2009134612A2 (en) 2009-11-05
WO2009134612A3 true WO2009134612A3 (en) 2009-12-30

Family

ID=41255676

Family Applications (1)

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PCT/US2009/040378 Ceased WO2009134612A2 (en) 2008-04-11 2009-04-13 Methods and compositions related to quantitative array based methylation analysis

Country Status (3)

Country Link
US (1) US9518288B2 (en)
EP (1) EP2274445A2 (en)
WO (1) WO2009134612A2 (en)

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WO2012103423A2 (en) * 2011-01-28 2012-08-02 Cornell University Computer-implemented platform for automated fluorescence imaging and kinetic analysis
GB201204727D0 (en) * 2012-03-16 2012-05-02 Base4 Innovation Ltd Method and apparatus
AU2013314405A1 (en) * 2012-09-11 2015-04-09 Unisense Diagnostics Aps Detection of non-nucleic acid analytes using strand displacement exchange reactions
KR101612885B1 (en) 2014-03-27 2016-04-26 고려대학교 산학협력단 Methods for Detection Methylation on Promoter and Methods for Detection and Tracking Epigenetics Alterations by DNA methylation Using Nanoplasmonic Biosensor
WO2020086764A1 (en) * 2018-10-24 2020-04-30 Chan Zuckerberg Biohub, Inc. Optical real-time biosensor
WO2021130750A1 (en) * 2019-12-22 2021-07-01 Ramot At Tel-Aviv University Ltd. Methods and arrays for identifying the cell or tissue origin of dna
WO2023086967A1 (en) * 2021-11-12 2023-05-19 Guardant Health, Inc. Method of analysis of methylated dna-binding proteins

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US20070264653A1 (en) * 2006-03-10 2007-11-15 Kurt Berlin Method of identifying a biological sample for methylation analysis

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Also Published As

Publication number Publication date
EP2274445A2 (en) 2011-01-19
US20110281746A1 (en) 2011-11-17
WO2009134612A2 (en) 2009-11-05
US9518288B2 (en) 2016-12-13

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