WO2009153017A3 - Vorrichtung zur serienmässigen gefriertrocknung - Google Patents

Vorrichtung zur serienmässigen gefriertrocknung Download PDF

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Publication number
WO2009153017A3
WO2009153017A3 PCT/EP2009/004312 EP2009004312W WO2009153017A3 WO 2009153017 A3 WO2009153017 A3 WO 2009153017A3 EP 2009004312 W EP2009004312 W EP 2009004312W WO 2009153017 A3 WO2009153017 A3 WO 2009153017A3
Authority
WO
WIPO (PCT)
Prior art keywords
lyophilization device
camera
images
scale lyophilization
scale
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/004312
Other languages
English (en)
French (fr)
Other versions
WO2009153017A2 (de
Inventor
Frank Böttger
Martin HÄUPTLE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Apotheker Vetter and Company Arzneimittel GmbH Ravensburg
Original Assignee
Apotheker Vetter and Company Arzneimittel GmbH Ravensburg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Apotheker Vetter and Company Arzneimittel GmbH Ravensburg filed Critical Apotheker Vetter and Company Arzneimittel GmbH Ravensburg
Priority to EP09765597.1A priority Critical patent/EP2310781B1/de
Priority to BRPI0914202 priority patent/BRPI0914202B1/pt
Priority to JP2011513940A priority patent/JP5897331B2/ja
Priority to RU2011101686/06A priority patent/RU2494323C2/ru
Priority to US12/999,021 priority patent/US8677649B2/en
Priority to CA2728365A priority patent/CA2728365C/en
Priority to MX2010013372A priority patent/MX2010013372A/es
Priority to ES09765597.1T priority patent/ES2595100T3/es
Publication of WO2009153017A2 publication Critical patent/WO2009153017A2/de
Publication of WO2009153017A3 publication Critical patent/WO2009153017A3/de
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B15/00—Special procedures for taking photographs; Apparatus therefor
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Drying Of Solid Materials (AREA)

Abstract

Es wird eine Vorrichtung zur serienmäßigen Gefriertrocknung pharmazeutischer Lösungen in medizinischen Hohlkörpern mit einer Gefriertrocknungseinrichtung und mindestens einer Kamera (9) vorgeschlagen, wobei von der mindestens einen Kamera (9) Bilder mindestens einer zur Gefriertrocknung bestimmten pharmazeutischen Lösung aufnehmbar sind, und wobei sich die Vorrichtung dadurch auszeichnet, dass die Bilder zur Steuerung und/oder Kontrolle des Gefriertrocknungsprozesses verwendbar sind.
PCT/EP2009/004312 2008-06-19 2009-06-16 Vorrichtung zur serienmässigen gefriertrocknung Ceased WO2009153017A2 (de)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP09765597.1A EP2310781B1 (de) 2008-06-19 2009-06-16 Vorrichtung und verfahren zur serienmässigen gefriertrocknung
BRPI0914202 BRPI0914202B1 (pt) 2008-06-19 2009-06-16 dispositivo para liofilização em série
JP2011513940A JP5897331B2 (ja) 2008-06-19 2009-06-16 大規模な凍結乾燥のための装置
RU2011101686/06A RU2494323C2 (ru) 2008-06-19 2009-06-16 Устройство для серийной сублимационной сушки
US12/999,021 US8677649B2 (en) 2008-06-19 2009-06-16 Large-scale lyophilization device
CA2728365A CA2728365C (en) 2008-06-19 2009-06-16 Large-scale lyophilization device
MX2010013372A MX2010013372A (es) 2008-06-19 2009-06-16 Dispositivo de liofilizacion a gran escala.
ES09765597.1T ES2595100T3 (es) 2008-06-19 2009-06-16 Dispositivo y proceso para el liofilizado en serie

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008030269A DE102008030269A1 (de) 2008-06-19 2008-06-19 Vorrichtung zur serienmäßigen Gefriertrocknung
DE102008030269.4 2008-06-19

Publications (2)

Publication Number Publication Date
WO2009153017A2 WO2009153017A2 (de) 2009-12-23
WO2009153017A3 true WO2009153017A3 (de) 2010-10-14

Family

ID=41335024

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/004312 Ceased WO2009153017A2 (de) 2008-06-19 2009-06-16 Vorrichtung zur serienmässigen gefriertrocknung

Country Status (11)

Country Link
US (1) US8677649B2 (de)
EP (1) EP2310781B1 (de)
JP (2) JP5897331B2 (de)
BR (1) BRPI0914202B1 (de)
CA (1) CA2728365C (de)
DE (1) DE102008030269A1 (de)
ES (1) ES2595100T3 (de)
MX (1) MX2010013372A (de)
PT (1) PT2310781T (de)
RU (1) RU2494323C2 (de)
WO (1) WO2009153017A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102008030269A1 (de) * 2008-06-19 2009-12-24 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Vorrichtung zur serienmäßigen Gefriertrocknung
EP2745064B1 (de) 2011-09-06 2017-04-05 Rheavita B.V. Verfahren und system zur gefriertrocknung injizierbarer zusammensetzungen, insbesondere pharmazeutischer zusammensetzungen
EP3769618A1 (de) * 2014-06-09 2021-01-27 Terumo BCT, Inc. Behälter zur lyophilisierung
DE102016100163B4 (de) 2016-01-05 2025-02-27 Martin Christ Gefriertrocknungsanlagen Gmbh Gefriertrockner-Steuereinrichtung, Verfahren zum Betrieb derselben, Gefriertrockner und Gefriertrocknungsanlage
MY181430A (en) 2016-08-16 2020-12-21 Rheavita Bv Method and apparatus and container for freeze-drying
KR20210024549A (ko) 2018-06-29 2021-03-05 우니베르지타이트 겐트 제품 용량 단위의 동결, 건조 및/또는 동결 건조
US11243029B2 (en) * 2019-04-26 2022-02-08 Purdue Research Foundation Process monitoring and control for lyophilization using a wireless sensor network
US11054185B1 (en) 2020-02-24 2021-07-06 Lyophilization Technology, Inc. Apparatus for lyophilization of products contained in product delivery units
CN115989390B (zh) * 2020-08-20 2024-10-25 豪夫迈·罗氏有限公司 冻干物保持器、其制造方法以及干燥底物的过程
US12085337B2 (en) 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods
CN116382202A (zh) * 2023-03-31 2023-07-04 楚天科技股份有限公司 一种冻干过程监测系统及冻干机

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1178787B (de) * 1959-06-11 1964-09-24 Centre Nat Rech Scient Verfahren und Geraet zum automatischen Steuern einer Gefriertrocknung
DE10310632A1 (de) * 2002-09-18 2004-04-01 Diestelhorst, Michael, Dr. Verfahren zum Herstellen eines lyophilisierten pharmazeutischen Materials und Anlage hierfür
US20060053652A1 (en) * 2002-11-21 2006-03-16 Gyory J R Freeze-drying microscope stage apparatus and process of using the same

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3627423A (en) * 1970-02-17 1971-12-14 Schering Corp Method and apparatus for detecting particular matter in sealed liquids
SU609037A1 (ru) * 1972-09-21 1978-05-30 Черновицкий Государственный Медицинский Институт Устройство дл лиофильной сушки образцов животных и растительных тканей
DE2854534C3 (de) * 1978-12-16 1982-02-11 B. Braun Melsungen Ag, 3508 Melsungen Zahnpulpenfüllmaterial
JP3212389B2 (ja) * 1992-10-26 2001-09-25 株式会社キリンテクノシステム 固体上の異物検査方法
JP3351910B2 (ja) * 1994-09-01 2002-12-03 エーザイ株式会社 バイアル瓶の検査方法と装置
JP2002014049A (ja) * 2000-04-13 2002-01-18 Eisai Co Ltd 凍結乾燥製剤の乾燥前における混入異物の検査方法及びその装置
SE0001453D0 (sv) 2000-04-19 2000-04-19 Astrazeneca Ab Method of monitoring a freeze drying process
JP4474663B2 (ja) * 2003-08-27 2010-06-09 努 升島 ビデオ顕微鏡装置
JP2005218686A (ja) * 2004-02-06 2005-08-18 Shibuya Kogyo Co Ltd 乾燥滅菌機
DE102008030269A1 (de) * 2008-06-19 2009-12-24 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Vorrichtung zur serienmäßigen Gefriertrocknung
US9063000B2 (en) * 2009-05-15 2015-06-23 Glaxosmithkline Llc Using thermal imaging for control of a manufacturing process

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1178787B (de) * 1959-06-11 1964-09-24 Centre Nat Rech Scient Verfahren und Geraet zum automatischen Steuern einer Gefriertrocknung
DE10310632A1 (de) * 2002-09-18 2004-04-01 Diestelhorst, Michael, Dr. Verfahren zum Herstellen eines lyophilisierten pharmazeutischen Materials und Anlage hierfür
US20060053652A1 (en) * 2002-11-21 2006-03-16 Gyory J R Freeze-drying microscope stage apparatus and process of using the same

Also Published As

Publication number Publication date
JP5897331B2 (ja) 2016-03-30
WO2009153017A2 (de) 2009-12-23
EP2310781A2 (de) 2011-04-20
PT2310781T (pt) 2016-11-08
CA2728365A1 (en) 2009-12-23
JP6062402B2 (ja) 2017-01-18
US8677649B2 (en) 2014-03-25
JP2011524512A (ja) 2011-09-01
ES2595100T3 (es) 2016-12-27
BRPI0914202A2 (pt) 2015-11-03
EP2310781B1 (de) 2016-08-17
BRPI0914202B1 (pt) 2019-12-03
JP2014224677A (ja) 2014-12-04
DE102008030269A1 (de) 2009-12-24
US20110099836A1 (en) 2011-05-05
CA2728365C (en) 2016-03-22
RU2011101686A (ru) 2012-07-27
MX2010013372A (es) 2011-03-21
RU2494323C2 (ru) 2013-09-27

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