WO2009153348A3 - Device for multiparametric assays - Google Patents

Device for multiparametric assays Download PDF

Info

Publication number
WO2009153348A3
WO2009153348A3 PCT/EP2009/057694 EP2009057694W WO2009153348A3 WO 2009153348 A3 WO2009153348 A3 WO 2009153348A3 EP 2009057694 W EP2009057694 W EP 2009057694W WO 2009153348 A3 WO2009153348 A3 WO 2009153348A3
Authority
WO
WIPO (PCT)
Prior art keywords
cap
well
side walls
top surface
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/057694
Other languages
French (fr)
Other versions
WO2009153348A2 (en
Inventor
Christophe Van Huffel
Jens Liedecker
Sandrine Hamels
Françoise De Longueville
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eppendorf Array Technologies SA
Original Assignee
Eppendorf Array Technologies SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eppendorf Array Technologies SA filed Critical Eppendorf Array Technologies SA
Priority to EP09765927A priority Critical patent/EP2328682A2/en
Publication of WO2009153348A2 publication Critical patent/WO2009153348A2/en
Publication of WO2009153348A3 publication Critical patent/WO2009153348A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50855—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates using modular assemblies of strips or of individual wells
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5085—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50853—Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/026—Fluid interfacing between devices or objects, e.g. connectors, inlet details
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0642—Filling fluids into wells by specific techniques
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0684—Venting, avoiding backpressure, avoid gas bubbles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/041—Connecting closures to device or container
    • B01L2300/042—Caps; Plugs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/047—Additional chamber, reservoir
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B01L2300/048—Function or devices integrated in the closure enabling gas exchange, e.g. vents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0851—Bottom walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0848—Specific forms of parts of containers
    • B01L2300/0858—Side walls
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

An assay device (C) compatible with multi-well format for performing a biological reaction between capture and target molecules, comprising: a cap (A) comprising side walls (7), and top surface (5) and a bottom surface (6), wherein the top surface (5) and bottom surface (6) are connected by at least one inlet channel (10) and at least one outlet channel (11) and wherein the top surface (5) of the cap (A) comprises a stopper indentation (15), a well (B) comprising side walls (3) and a bottom surface (4) upon which capture molecules are immobilized, wherein the cap (A) and the well (B) are made of different polymeric materials being preferably cycloolefin polymer for the cap (A) and polypropylene for the well (B), - wherein the side walls (7) of the cap (A) and the side walls (3) of the well (B) comprises complementary screwing means (12,13) to seal the cap (A) inside the well (B) to form a chamber (1) between the bottom surface (6) of the cap (A) and the bottom surface (4) of the well (B) and wherein the two said surfaces are essentially parallel to each other with a variation of distance between the two surfaces lower than 100 μm, better lower than 20 μm and, wherein the chamber (1) has a height of less than 5 mm, preferably less than 2 mm and which is vapour and fluid tight, when the cap (A) is sealed inside the well (B).
PCT/EP2009/057694 2008-06-19 2009-06-19 Device for multiparametric assays Ceased WO2009153348A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09765927A EP2328682A2 (en) 2008-06-19 2009-06-19 Device for multiparametric assays

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08158551.5 2008-06-19
EP08158551A EP2135674A1 (en) 2008-06-19 2008-06-19 Device for multiparametrics assays

Publications (2)

Publication Number Publication Date
WO2009153348A2 WO2009153348A2 (en) 2009-12-23
WO2009153348A3 true WO2009153348A3 (en) 2010-03-18

Family

ID=39967935

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/057694 Ceased WO2009153348A2 (en) 2008-06-19 2009-06-19 Device for multiparametric assays

Country Status (2)

Country Link
EP (2) EP2135674A1 (en)
WO (1) WO2009153348A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2865097A1 (en) * 2012-02-20 2013-08-29 Advanced Tactical Ordnance LLC Chimeric dna identifier
AU2013202778A1 (en) * 2013-03-14 2014-10-02 Gen-Probe Incorporated Systems, methods, and apparatuses for performing automated reagent-based assays
USD765215S1 (en) 2015-01-22 2016-08-30 United Tactical Systems, Llc Non-lethal projectile
CA3130201A1 (en) * 2019-03-14 2020-09-17 Marc DEJOHN Vial caps for biological processing or analysis

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030049862A1 (en) * 2001-09-07 2003-03-13 Lin He Microcolumn-based, high-throughput microfluidic device
WO2005110600A2 (en) * 2004-05-18 2005-11-24 Nunc A/S Tube, cap and rack for automatic handling of samples
US20070104617A1 (en) * 2005-11-04 2007-05-10 Advanced Biotechnologies Limited Capped tubes
EP1852186A1 (en) * 2006-05-03 2007-11-07 Eppendorf Array Technologies Method and means for multiparametric assays being compartmentalized
WO2007131999A1 (en) * 2006-05-17 2007-11-22 Eppendorf Array Technologies S.A. Lid for pcr vessel comprising probes permitting pcr amplification and detection of the pcr product by hybridisation without opening the pcr vessel

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312527A (en) 1992-10-06 1994-05-17 Concordia University Voltammetric sequence-selective sensor for target polynucleotide sequences
JP2002515738A (en) 1996-01-23 2002-05-28 アフィメトリックス，インコーポレイティド Nucleic acid analysis
US20050023672A1 (en) 2003-07-01 2005-02-03 Affymetrix, Inc. Device and method for immersed array packaging and processing
EP1724360A1 (en) 2005-05-17 2006-11-22 Eppendorf Array Technologies S.A. Identification and/or quantification method of nucleotide sequence(s) elements specific of genetically modified plants on arrays
EP1847316A1 (en) 2006-04-19 2007-10-24 Eppendorf Array Technologies SA (EAT) Method for stabilizing functional groups on a surface of a polymer used as solid support for making microarrays

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030049862A1 (en) * 2001-09-07 2003-03-13 Lin He Microcolumn-based, high-throughput microfluidic device
EP1391242A2 (en) * 2002-05-24 2004-02-25 Corning Incorporated Microcolumn based high throughput microfluidic device
WO2005110600A2 (en) * 2004-05-18 2005-11-24 Nunc A/S Tube, cap and rack for automatic handling of samples
US20070104617A1 (en) * 2005-11-04 2007-05-10 Advanced Biotechnologies Limited Capped tubes
EP1852186A1 (en) * 2006-05-03 2007-11-07 Eppendorf Array Technologies Method and means for multiparametric assays being compartmentalized
WO2007131999A1 (en) * 2006-05-17 2007-11-22 Eppendorf Array Technologies S.A. Lid for pcr vessel comprising probes permitting pcr amplification and detection of the pcr product by hybridisation without opening the pcr vessel

Also Published As

Publication number Publication date
EP2135674A1 (en) 2009-12-23
WO2009153348A2 (en) 2009-12-23
EP2328682A2 (en) 2011-06-08

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