WO2010124633A1 - 底部控制式标本过滤容器和方法 - Google Patents

底部控制式标本过滤容器和方法 Download PDF

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WO2010124633A1
WO2010124633A1 PCT/CN2010/072273 CN2010072273W WO2010124633A1 WO 2010124633 A1 WO2010124633 A1 WO 2010124633A1 CN 2010072273 W CN2010072273 W CN 2010072273W WO 2010124633 A1 WO2010124633 A1 WO 2010124633A1
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layer
piston rod
cup body
drainage needle
container
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French (fr)
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廖清华
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Priority to JP2012507594A priority Critical patent/JP5499158B2/ja
Priority to BRPI1015450-7A priority patent/BRPI1015450B1/pt
Priority to EP10769322.8A priority patent/EP2425884B1/en
Priority to US13/264,954 priority patent/US8268171B2/en
Publication of WO2010124633A1 publication Critical patent/WO2010124633A1/zh
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0038—Devices for taking faeces samples; Faecal examination devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0096—Casings for storing test samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/06—Valves, specific forms thereof
    • B01L2400/0633—Valves, specific forms thereof with moving parts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Rigid containers without fluid transport within
    • B01L3/5082—Test tubes per se
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration

Definitions

  • the invention relates to a filtering device and a filtering method, in particular to a bottom controlled type specimen filtering container and a bottom controlled type specimen filtering method.
  • FIGs 1 and 2 Existing filter containers, such as 'disposable fecal concentrate containers', are shown in Figures 1 and 2.
  • Figure 1 manually remove the top safety pin 1 of the container and manually poke the bottom center hole in the container to make the liquid flow downward through the bottom filter; or as shown in Figure 2, pull the safety plug 2 on the side of the container by hand. Open the center hole to allow the liquid to flow down.
  • the disadvantage is that it can only be manually controlled by the top safety pin or the side safety cover, and can only be turned on and off, can not control the amount of filtration, and can only filter all the liquid in the container at one time.
  • the solution of the present invention is:
  • the bottom control type specimen filtering container is composed of a sealing plug, a cup cover, a cup body, a piston rod, a piston, a clutch spring, a drainage needle and a bottom cover.
  • the piston rod is placed in the middle hole at the bottom of the cup body, and the piston is tightly sleeved on the piston rod
  • the drainage needle is fixed to the lower end of the piston rod by a screw connection
  • one end of the clutch spring abuts against the bottom of the cup body, and the other end abuts on the flange of the drainage needle, and a first layer filter and a second layer filter are also provided.
  • the double-layer filtration system is composed of a shaft of the first filter passing through the middle hole of the second filter and fixed in the top hole of the piston rod.
  • the bottom control type specimen filter container is further provided with a sampler, and the sampler is installed in a designated hole of the lid.
  • the lower end surface of the first layer filter has a gap with the upper end surface of the piston, and the height of the gap is greater than the thickness of the second layer filter.
  • the bottom control type specimen filtering method has the following steps:
  • the solution to be filtered is directly filled into the cup body, and the lid is covered;
  • the solid specimen the solid specimen is first loaded into the cup body, and the lid and the sealing plug are covered, similarly The device of the syringe penetrates the soft hole reserved in the middle of the sealing plug, injects the liquid in which the solid sample is dissolved into the cup body, and shakes;
  • the bottom cover is removed and the receiving container is placed under the drainage needle
  • the receiving container is pushed up, and the clutch spring is compressed, so that the drainage needle moves upward in the cup together with the piston, the piston rod and the double-layer filtering system, and opens the bottom of the cup body, so that the solution flows in and out from the bottom of the cup body.
  • the clutch spring is compressed, so that the drainage needle moves upward in the cup together with the piston, the piston rod and the double-layer filtering system, and opens the bottom of the cup body, so that the solution flows in and out from the bottom of the cup body.
  • the receiving container is moved downward, and the drainage needle is reset by the clutch spring together with the piston, the piston rod and the double-layer filtering system, and the bottom of the cup body is closed to complete the filtration.
  • the invention uses the test tube or other receiving container to directly control the opening or closing of the container containing the specimen solution, that is, the specimen filtering container, which has good sanitation and sealing property, and can be opened and closed, and the filtering amount can be controlled.
  • the liquid in the container can be filtered in fractions as needed, which is very convenient.
  • Figure 1 is a schematic view showing the structure of a conventional disposable feces concentrating container
  • FIG. 2 is a schematic structural view of another disposable fecal concentration container
  • Figure 3 is a schematic view of the appearance of the present invention.
  • Figure 4 is a schematic view of the structure of the present invention.
  • Figure 5 is a schematic view showing the filtration state of the present invention.
  • Figure 6 is an exploded perspective view of the present invention.
  • 3 to 6 are preferred embodiments of the present invention.
  • the bottom control type specimen filtering container is composed of a sealing plug 1, a cup cover 2, a cup body 3, a piston rod 5, a piston 6, a clutch spring 7, a drainage needle 8, and a bottom cover 9, and the piston rod 5 is placed in the middle of the bottom of the cup body.
  • the piston 6 is tightly sleeved on the protrusion of the piston rod 5.
  • the drainage needle 8 is fixed to the lower end of the piston rod 5 by a screw connection, and one end of the clutch spring 7 abuts against the bottom of the cup body 3, and the other end abuts against the drainage needle 8 method.
  • the bottom control type specimen filter container is also provided with a sampler 10 which is mounted in a designated hole of the lid 2 of the cup.
  • the gap height H between the lower end surface of the first layer filter 4 and the upper end surface of the piston 6 is larger than the thickness d of the second layer filter 11.
  • the solution to be filtered is loaded into the filter container by the sampler 10, and the unsealed plug 1 is not required to be sealed. If it is a solid specimen (such as a stool specimen) that needs to be sealed and dissolved, use a sampler 10 to put it into the container and then add a sealing plug 1. Use a syringe-like device to pierce the soft hole reserved in the middle of the sealing plug 1 to dissolve. The liquid of the solid specimen is injected into the container. Then, the bottom cover 9 is removed, the test tube or other receiving container is placed under the drainage needle 8, and the drainage needle 8 is pushed upward. The drainage needle 8 compresses the clutch spring 7 to push the piston rod 5 to drive the piston 6, and the first layer of filter 4 is upward.
  • a solid specimen such as a stool specimen
  • the second filter 11 is also moved up by the piston 6, and at this time, a certain space is formed between the first filter 4 and the second filter 11 to serve as a double layer.
  • the effect of the filtration continues to move up until the specimen in the container flows down through the gap between the upper end surface of the cup bottom and the lower end surface of the piston 6, and flows out through the drainage needle 8.
  • the drainage needle 8 is released, and the clutch spring 7 retracts the drainage needle 8 to the home position, and the piston 6 blocks the gap, thereby controlling the outward flow of the specimen.
  • the invention has the advantages of good sanitation, good sealing property, and the liquid in the container can be filtered in stages according to needs.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Medical Informatics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Microbiology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)

Description

底部控制式标本过滤容器和方法 技术领域
本发明涉及一种过滤装置和过滤方法，具体是指一种底部控制式标本过滤容器和一种底部控制式标本过滤方法。
背景技术
在医学实验室、生物实验室等领域，需要过滤容器对所取液体样本如粪便、尿液、河水等进行过滤。现有的过滤容器，比如'一次性粪便浓缩容器'如图1、图2。如图1，采取手动去除容器顶部保险栓1后手动戳开容器内底部中心圆孔使液体向下流过底部过滤网；或如图2，在容器侧面利用手拉方式将安全塞2拉开，使中心孔打开让液体流下。其缺点在于：只能通过顶部保险栓或者侧面安全套手动控制，且只能开不能关，不能控制过滤量，只能一次性过滤完容器内的所有液体。
发明内容
本发明的目的在于提供一种底部控制式标本过滤容器和方法，使容器内的液体可以分次过滤。
为了达成上述目的，本发明的解决方案是：
底部控制式标本过滤容器，由密封塞、杯盖、杯体、活塞杆、活塞、离合弹簧、引流针、底盖构成，活塞杆置于杯体底部的中间孔内，活塞紧套在活塞杆的凸起上，引流针通过螺纹连接固定在活塞杆下端，离合弹簧一端抵在杯体底部上，另一端抵在引流针法兰上，还设有第一层过滤网和第二层过滤网组成的双层过滤系统，第一层过滤网的轴穿过第二层过滤网中间孔并固定在活塞杆顶端孔内。
所述底部控制式标本过滤容器还设有取样器，取样器安装在杯盖指定孔内。
所述第一层过滤网的下端面与活塞的上端面存有间隙，此间隙的高度大于第二层过滤网的厚度。
底部控制式标本过滤方法，其步骤如下：
第一步，对于液体标本，是直接将需要过滤的溶液装入杯体中，盖好杯盖；对于固体标本，先将固体标本装入杯体中，盖好杯盖和密封塞，用类似注射器的装置刺透密封塞中间预留的软性孔，把溶解固体标本的液体注入杯体中，并摇匀；
第二步，取下底盖，将接收容器放置到引流针下面；
第三步，将接收容器向上推，压缩离合弹簧，使引流针与活塞、活塞杆、双层过滤系统一起在杯体中向上移，开启杯体的底部，使溶液从杯体的底部流入接收容器中；
第四步，当标本溶液收集到所需用量时，将接收容器向下移，引流针与活塞、活塞杆、双层过滤系统一起由离合弹簧复位，关闭杯体的底部，完成过滤。
采用上述方案后，本发明使用时是利用试管或其他接收容器直接控制开启或关闭盛装标本溶液的容器即标本过滤容器，卫生、封闭性好，而且，能开能关，可以控制过滤量，使容器内的液体可以根据需要分次过滤，十分方便。
以下结合附图及具体实施例对本发明做进一步详细说明。
附图说明
图1是现有的一种一次性粪便浓缩容器结构示意图；
图2是现有的另一种一次性粪便浓缩容器结构示意图；
图3是本发明的外观示意图；
图4是本发明的结构示意图；
图5是本发明的过滤状态示意图；
图6是本发明的立体分解图。
标号说明
密封塞1杯盖2
杯体3第一层过滤网4
活塞杆5活塞6
离合弹簧7引流针8
底盖9取样器10
中间孔12第二层过滤网11
具体实施方式
如图3至图6所示，是本发明的较佳实施例。
底部控制式标本过滤容器，由密封塞1、杯盖2、杯体3、活塞杆5、活塞6、离合弹簧7、引流针8、底盖9构成，活塞杆5置于杯体底部的中间孔12内，活塞6紧套在活塞杆5的凸起上，引流针8通过螺纹连接固定在活塞杆5下端，离合弹簧7一端抵在杯体3底部上，另一端抵在引流针8法兰上，还设有第一层过滤网4和第二层过滤网11组成的双层过滤系统，第一层过滤网4的轴穿过第二层过滤网11中间孔并固定在活塞杆5顶端孔内。
底部控制式标本过滤容器还设有取样器10，取样器10安装在杯盖2指定孔内。
此实施例中，为了使双层过滤系统的过滤效果最佳，第一层过滤网4的下端面与活塞6的上端面之间的间隙高度H大于第二层过滤网11的厚度d。
使用时通过取样器10把需要过滤的溶液装入过滤容器，无需密闭可加不密封塞1。如果是固体标本（如粪便标本）需要密闭溶解过滤的，使用取样器10将之放入容器后加密封塞1，用类似注射器的装置刺透密封塞1中间预留的软性孔，把溶解固体标本的液体注入容器。然后把底盖9取下，将试管或其他接收容器放置到引流针8下面，推动引流针8向上移动，引流针8压缩离合弹簧7推动活塞杆5带动活塞6、第一层过滤网4向上移动，当上移一定的位移时第二层过滤网11在活塞6的推动下也上移，此时第一层过滤网4与第二层过滤网11中间形成一定的空间，起到双层过滤的效果，继续上移直到容器内标本通过杯底上端面与活塞6下端面的间隙流下，通过引流针8流出。停止时，松开引流针8，离合弹簧7将引流针8退回到原位，活塞6把间隙堵上，即控制了标本向外流出。本发明具有卫生、封闭性好，容器内的液体可以根据需要分次过滤的优点。
上述为本发明的一个具体实施方式，但本发明的设计构思并不局限于此，凡利用此构思对本发明进行非实质性的改动，均属于侵犯本发明保护范围的行为。

Claims (4)

1、底部控制式标本过滤容器，由密封塞、杯盖、杯体、活塞杆、活塞、离合弹簧、引流针、底盖构成，活塞杆置于杯体底部的中间孔内，活塞紧套在活塞杆的凸起上，引流针通过螺纹连接固定在活塞杆下端，离合弹簧一端抵在杯体底部上，另一端抵在引流针法兰上，其特征在于：还设有第一层过滤网和第二层过滤网组成的双层过滤系统，第一层过滤网的轴穿过第二层过滤网中间孔并固定在活塞杆顶端孔内。
2、如权利要求1所述的底部控制式标本过滤容器，其特征在于：还设有取样器，取样器安装在杯盖指定孔内。
3、如权利要求1所述的底部控制式标本过滤容器，其特征在于：第一层过滤网的下端面与活塞的上端面存有间隙，此间隙的高度大于第二层过滤网的厚度。
4、底部控制式标本过滤方法，其特征在于步骤如下：
第一步，对于液体标本，是直接将需要过滤的溶液装入杯体中，盖好杯盖；对于固体标本，先将固体标本装入杯体中，盖好杯盖和密封塞，用类似注射器的装置刺透密封塞中间预留的软性孔，把溶解固体标本的液体注入杯体中，并摇匀；
第二步，取下底盖，将接收容器放置到引流针下面；
第三步，将接收容器向上推，压缩离合弹簧，使引流针与活塞、活塞杆、双层过滤系统一起在杯体中向上移，开启杯体的底部，使溶液从杯体的底部流入接收容器中；
第四步，当标本溶液收集到所需用量时，将接收容器向下移，引流针与活塞、活塞杆、双层过滤系统一起由离合弹簧复位，关闭杯体的底部，完成过滤。
PCT/CN2010/072273 2009-04-28 2010-04-28 底部控制式标本过滤容器和方法 Ceased WO2010124633A1 (zh)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2012507594A JP5499158B2 (ja) 2009-04-28 2010-04-28 底部制御式標本フィルタリング容器及び方法
BRPI1015450-7A BRPI1015450B1 (pt) 2009-04-28 2010-04-28 Dispositivo e método de filtragem de espécime de controle de fundo
EP10769322.8A EP2425884B1 (en) 2009-04-28 2010-04-28 Bottom control type specimen filtering container and method thereof
US13/264,954 US8268171B2 (en) 2009-04-28 2010-04-28 Bottom control type specimen filtering container and filtering method thereof

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CN200920151032.6 2009-04-28
CN2009201510326U CN201404734Y (zh) 2009-04-28 2009-04-28 底部控制式标本过滤容器

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EP (1) EP2425884B1 (zh)
JP (1) JP5499158B2 (zh)
CN (1) CN201404734Y (zh)
BR (1) BRPI1015450B1 (zh)
WO (1) WO2010124633A1 (zh)

Cited By (3)

* Cited by examiner, † Cited by third party
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US8268171B2 (en) * 2009-04-28 2012-09-18 Qinghua Liao Bottom control type specimen filtering container and filtering method thereof
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EP2425884A1 (en) 2012-03-07
JP5499158B2 (ja) 2014-05-21
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