WO2011106802A1 - Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide - Google Patents

Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide Download PDF

Info

Publication number
WO2011106802A1
WO2011106802A1 PCT/ZA2010/000010 ZA2010000010W WO2011106802A1 WO 2011106802 A1 WO2011106802 A1 WO 2011106802A1 ZA 2010000010 W ZA2010000010 W ZA 2010000010W WO 2011106802 A1 WO2011106802 A1 WO 2011106802A1
Authority
WO
WIPO (PCT)
Prior art keywords
plunger
barrel
applicator
charged
biasing means
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/ZA2010/000010
Other languages
English (en)
Inventor
Jacobus Adriaan Wessels
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to PCT/ZA2010/000010 priority Critical patent/WO2011106802A1/fr
Publication of WO2011106802A1 publication Critical patent/WO2011106802A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D7/00—Devices or methods for introducing solid, liquid, or gaseous remedies or other materials into or onto the bodies of animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body

Definitions

  • This invention relates to an applicator for semiliquid / semisolid (hereinafter referred to as semiliquid) medical and veterinary preparations such as creams, gels and pastes and, more particularly, the invention relates to an applicator that is particularly suitable for dispensing a predetermined quantity of the semiliquid preparation.
  • the invention relates to an applicator that is suitable for dispensing a predetermined quantity of semiliquid preparation into a body cavity especially the vagina, but also the rectum, mouth, nose and ear. It will be quite apparent to those skilled in the art that the applicator can also be used to excellent effect in numerous veterinary applications in which an animal such as a cat or dog can bite onto the hard barrel of an applicator as the veterinary preparation is administered.
  • Vaginal applicators that are presently available on the market are, as far as applicant is aware, either made from plastic or cardboard. In general these applicators consist of a barrel for receiving the medical preparation and a plunger for expelling the preparation from the barrel. The applicators may be pre-filled or user filled and may be designed to be re-usable or disposable single-use products. Numerous different vaginal medical preparations are in common use or are planned for future use and these include contraceptive and microbicidal preparations as well as numerous different medicinal and lubricating preparations.
  • an applicator is able to deliver the correct predetermined quantity of a medical preparation. This involves, in the instance of user filled applicators, properly filling the applicator and, in the instance of either prefilled or user filled applicators, ensuring that the entire predetermined quantity is discharged.
  • an applicator for a semiliquid medical or veterinary preparation comprising a barrel having an open delivery end and an opposite operating end, and a plunger movable along the length of the barrel between a charged position in which it is located towards the operating end of the barrel and a discharged position in which it is located towards the delivery end of the barrel, the applicator being characterised in that it includes biasing means that have a loaded condition corresponding to the charged position of the plunger and an unloaded position corresponding to the discharged position of the plunger with the biasing means being operative to move the plunger from its charged position to its discharged position upon release thereof, manually releasable catch means for holding the biasing means in the loaded condition, and a safety unit preventing operation of the manually releasable catch means unless the plunger is in its charged position.
  • biasing means to be associated with an axially movable operating stem to bias the stem towards a position corresponding to the discharged position of the plunger; for the biasing means to be one or more springs; for the catch means to include a spring biased latch cooperating with a formation in the operating stem; for the safety unit to be a transfer element movable in unison with the plunger so that it enables operation of the manually releasable catch means only when it is in registration with a manually movable component of the releasable catch means; for the barrel to have an external removable and optionally disposable outer sleeve; for the outer sleeve to extend beyond the open discharge end of the barrel to occlude such end of the barrel and isolate it from body fluids, in use; for the outer sleeve to have connector means for. attaching it to a dispensing tube or other container; and for visible indicator means to be provided for indicating when the plunger is in its terminal loaded position.
  • an operating stem for moving the plunger from its charged position to its discharged position
  • the operating stem and plunger are movable to their loaded and charged positions independently of each other so that the biasing means may be charged whilst the plunger remains in its discharged position.
  • Introduction of medical preparation into the barrel from the open discharge end of the barrel moves the plunger towards the operating end of the barrel such that only once the barrel is full is a transfer element in registration with a manually movable component of the releasable catch means. Accordingly, with a specifically designed barrel and plunger, the releasable catch means cannot be operated unless the plunger has been moved fully to the charged position corresponding to a particular quantity of semiliquid preparation having been introduced into the barrel in order to move the plunger.
  • Figure 1 is a front elevation of one embodiment of the invention
  • Figure 2 is a sectional elevation taken along line II - II in Figure 1 ;
  • Figure 3 is an enlarged sectional elevation of the operating end of the applicator when the plunger is between its discharged position and a charged position being a position in which the manually operable release catch cannot be operated;
  • Figure 4 is the same as Figure 3 but showing the arrangement with the plunger in its fully charged condition and the catch means in a condition in which it is operable;
  • Figure 5 is an elevation illustrating the removable external sleeve and co-operating barrel of the applicator.
  • a vaginal applicator (1) for a semiliquid medical preparation comprises a barrel (2) having an open delivery end (3) and an opposite operating end (4).
  • a plunger (5) in this instance of generally spherical shape, is movable along the length of the barrel between a charged position in which it is located towards the operating end of the barrel, as illustrated in Figures 2 and 4, and a discharged position in which it is retained within the barrel at the delivery end by means of an inwardly directed lip (6), as illustrated in dotted lines in Figure 2.
  • a rearwardly extending strip (7) that communicates tangentially with the plunger is formed integral with it. The strip is located at one side of the barrel and serves the purposes of an indicator and of a transfer element for co-operation with the catch mechanism as described hereinafter.
  • the plunger is, apart from any friction between it and the barrel wall, freely movable within the barrel and is in cooperating relationship relative to an axially extending stem (8) that has an engagement flange (9) at its inner end for contacting the plunger and an operating handle (10) at its outer end.
  • the flange has a cutout for accommodating the strip where it passes the flange.
  • Biasing means in the form of a compression spring, generally indicated by numeral (1 1 ), encircles the stem between the operating end of the barrel and the flange.
  • the flange and the stem are thus biased, in the loaded condition, towards a position corresponding to the discharged position of the plunger and are able to move the plunger to its discharged position when the plunger is in its charged position.
  • the stem therefore has a loaded condition corresponding to the charged position of the plunger in which it is retained by a latch (12) against the action of the spring (see Figure 4), and an unloaded position corresponding to the discharged position of the plunger.
  • the latch engages in a notch (13) in the stem to hold it longitudinally against the action of the spring. It will be understood that, once the latch is released, the stem and thus the plunger are moved under the action of the spring from the loaded and charged positions to the unloaded and discharged positions respectively.
  • the latch forms part of a manually releasable catch means that includes a manually operable flexible release button (14) carrying a manually movable component (15) that is to release the latch when the release button is depressed and the plunger is in its charged position.
  • a small frame (16) is interposed between the movable component (15) and latch (12) and is arranged such that the manually movable component simply enters the frame without releasing the catch in the absence of the strip (7) carried by the plunger (5) that serves as the transfer element.
  • the length of the strip is selected such that when the barrel is full and the plunger is in its charged position, only then is the end region of the strip in registration with the frame such that the movable component carried by the flexible release button can engage the frame by way of the strip so that the frame engages the latch to release it. In this manner operation of the manually releasable catch means is prevented unless the plunger is in its charged position and that only happens when the barrel is full because of the free-floating plunger and attached strip that serves as the transfer element defined above.
  • the strip that is attached to the plunger also serves the purpose of an indicator by virtue of coloured regions of the strip that are visible through an inspection aperture (17) at the operating end of the barrel. These coloured regions come into registration with the inspection aperture such that a red colour is visible initially and only when the plunger is in its fully charged position is a green colour visible through the inspection aperture.
  • the barrel itself in this embodiment of the invention, is designed to be maintained out of contact with body fluids by means of an external removable and optionally disposable outer sleeve (18) (see Figure 5) that is a frictional fit over the outer surface of the barrel.
  • the outer sleeve in its operative position, extends beyond the open discharge end of the barrel, as shown in Figure 2, to occlude the end of the barrel and isolate it from body fluids, in use.
  • the outer sleeve has connector means the form, for example, of an appropriately dimensioned socket (19) for attaching it to a dispensing tube or other container from which medical preparation is to be sourced.
  • the biasing means may be charged whilst the plunger remains in its discharged position. Introduction of medical preparation into the barrel from the open discharge end of the barrel moves the plunger towards the operating end of the barrel such that only when the barrel is full is the strip in registration with the manually movable component of the releasable catch means.
  • the releasable catch means cannot be operated unless the plunger has been moved fully to the charged position corresponding to a particular quantity of semiliquid preparation having been introduced into the barrel in order to move the plunger.
  • This ensures that a user fills the applicator with the correct amount of medical preparation.
  • the sleeve serves firstly to prevent contamination from one use to the next as a small amount of medical preparation stays behind in the delivery end of the sleeve thereby creating a barrier between the outlet of the sleeve and the delivery end of the barrel. This is aimed at preventing body fluids from contacting the barrel itself.
  • the applicator cannot be filled if the sleeve is not on the barrel as the sleeve has the socket for connection to a supply tube, for example. Whilst it is generally possible for the sleeves to be reusable, it is preferred that they are disposable.
  • the transfer element could be a freely movable element located in a transverse hole in a piston rod carried by the plunger.
  • the flexible release button or manually movable element simply needs to be in registration with the freely movable element in order to release the latch which only occurs when the plunger is in its charged position.
  • an outer part of the stem could be flexible and, especially, longitudinally extensible, such as by being made as a flexible sinuous or zigzag member.
  • that part of the stem could contract longitudinally once the stem is in its charged position in order to reduce the size of the applicator when charged.
  • This arrangement could also prevent a user from pressing onto the stem in an effort to bypass the trigger button.
  • That part of the stem could alternatively be simply a flexible piece of string.
  • the outer sleeve is not entirely necessary and the applicator could be designed for use without a replaceable sleeve.
  • the barrel could also have a removable and replaceable tip.
  • the plunger can assume any configuration, as will be quite apparent to those skilled in the art.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention porte sur un applicateur [1] pour l'administration d'une quantité prédéterminée d'une préparation semi-liquide dans une cavité corporelle, en particulier le vagin, mais également éventuellement le rectum, la bouche, le nez et l'oreille. L'applicateur comprend un tube [2] ayant une extrémité d'administration ouverte [3] et une extrémité de commande opposée [4], et un plongeur [5] pouvant se déplacer le long de la longueur du tube entre une position chargée dans laquelle il est localisé vers l'extrémité de commande du tube et une position déchargée dans laquelle il est localisé vers l'extrémité d'administration du tube. Des moyens de sollicitation [11] ont un état chargé électriquement correspondant à la position chargée du plongeur et une position non chargée électriquement correspondant à la position déchargée du plongeur, les moyens de sollicitation permettant de déplacer le plongeur de sa position chargée à sa position déchargée lors de la libération de celui-ci. Des moyens de capture manuellement libérables [12] maintiennent les moyens de sollicitation dans l'état chargé électriquement. Une unité de sécurité [15, 16] empêche le fonctionnement des moyens de capture manuellement libérables jusqu'à ce que le plongeur soit dans sa position chargée. De préférence, une tige de commande est prévue pour déplacer le plongeur de sa position chargée à sa position déchargée et la tige de commande et le plongeur peuvent se déplacer indépendamment l'un de l'autre vers leur position chargée électriquement et leur position chargée afin que les moyens de sollicitation puissent être chargés tandis que le plongeur reste dans sa position déchargée.
PCT/ZA2010/000010 2010-02-23 2010-02-23 Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide Ceased WO2011106802A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/ZA2010/000010 WO2011106802A1 (fr) 2010-02-23 2010-02-23 Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/ZA2010/000010 WO2011106802A1 (fr) 2010-02-23 2010-02-23 Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide

Publications (1)

Publication Number Publication Date
WO2011106802A1 true WO2011106802A1 (fr) 2011-09-01

Family

ID=44507263

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ZA2010/000010 Ceased WO2011106802A1 (fr) 2010-02-23 2010-02-23 Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide

Country Status (1)

Country Link
WO (1) WO2011106802A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ305392B6 (cs) * 2006-04-27 2015-09-02 RenĂ© Breila Aplikační pomůcka pro orální konzumaci zejména léků
EP2723673B1 (fr) * 2011-06-24 2020-01-22 Heidi Hall Mors et système pour envoyer une substance visqueuse et/ou liquide dans la bouche d'un animal

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358489A (en) * 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
WO2005023341A1 (fr) * 2003-09-11 2005-03-17 Tecpharma Licensing Ag Dispositif d'administration pour produit injectable equipe d'une securite anti-declenchement
WO2009040605A1 (fr) * 2007-09-25 2009-04-02 Becton Dickinson France Injecteur automatique à déclencheur positionnable dans une position active par mouvement d'un écran protecteur et indication de la position active

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358489A (en) * 1993-05-27 1994-10-25 Washington Biotech Corporation Reloadable automatic or manual emergency injection system
WO2005023341A1 (fr) * 2003-09-11 2005-03-17 Tecpharma Licensing Ag Dispositif d'administration pour produit injectable equipe d'une securite anti-declenchement
WO2009040605A1 (fr) * 2007-09-25 2009-04-02 Becton Dickinson France Injecteur automatique à déclencheur positionnable dans une position active par mouvement d'un écran protecteur et indication de la position active

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ305392B6 (cs) * 2006-04-27 2015-09-02 RenĂ© Breila Aplikační pomůcka pro orální konzumaci zejména léků
EP2723673B1 (fr) * 2011-06-24 2020-01-22 Heidi Hall Mors et système pour envoyer une substance visqueuse et/ou liquide dans la bouche d'un animal

Similar Documents

Publication Publication Date Title
US7744558B2 (en) Pill plunger
US10583252B2 (en) Veterinary syringe for multiple injections
CN104684606B (zh) 快速释放柱塞
US20230310757A1 (en) Syringe adapter for medication
JP2018524109A5 (fr)
US8038651B2 (en) Device with pressure-actuated pistons for dispensing a multiple syringe or multiple cartridge
US20070244444A1 (en) Adjustable dosage syringe
CN111032124B (zh) 用于注射容纳在医疗容器中的组合物的辅助注射装置
JP7696395B2 (ja) 複式逆止弁の片手操作式アプリケータ
US11013898B2 (en) Applicator for dispensing a medical substance and methods associated therewith
US20120215205A1 (en) Plunger-driven feeding tube delivery device and methods
CN107397606A (zh) 一种兽医用注射器
DK2306960T3 (en) FLUID TRANSFER DEVICE
CN211273092U (zh) 一种妇科护理用给药器
WO2011106802A1 (fr) Applicateur de préparations médicale et vétérinaire semi-liquide/semi-solide
CN111655324A (zh) 鼻内施用装置
EP3030193B1 (fr) Appareil doseur
JP7326288B2 (ja) 特に歯科用ペースト状組成物を投与するための、後流無しの注射器
US6213984B1 (en) Self-metering cartridge
KR102086991B1 (ko) 나팔관에 폐색 화합물을 투여하기 위한 애플리케이터
US11911600B2 (en) Injection device for injecting a composition contained in a medical container
CA3121133C (fr) Adaptateur de seringue pour medicament
CN121443256A (zh) 用于同时抽取并分配至少两种产品的器械
CN214259562U (zh) 大小鼠胶囊给药器
CN108543211B (zh) 一种皮肤科药膏涂抹器

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10846807

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10846807

Country of ref document: EP

Kind code of ref document: A1