WO2012116336A3 - Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system - Google Patents

Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system Download PDF

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Publication number
WO2012116336A3
WO2012116336A3 PCT/US2012/026637 US2012026637W WO2012116336A3 WO 2012116336 A3 WO2012116336 A3 WO 2012116336A3 US 2012026637 W US2012026637 W US 2012026637W WO 2012116336 A3 WO2012116336 A3 WO 2012116336A3
Authority
WO
WIPO (PCT)
Prior art keywords
blood
clip assembly
sensor clip
blood chamber
chamber
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2012/026637
Other languages
French (fr)
Other versions
WO2012116336A2 (en
Inventor
Louis L. Barrett
Perry N. Law
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fresenius Medical Care Holdings Inc
Original Assignee
Fresenius Medical Care Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/034,788 external-priority patent/US8517968B2/en
Application filed by Fresenius Medical Care Holdings Inc filed Critical Fresenius Medical Care Holdings Inc
Priority to CN201280010099.2A priority Critical patent/CN103796709B/en
Priority to MX2013009761A priority patent/MX2013009761A/en
Priority to JP2013555623A priority patent/JP5940099B2/en
Priority to AU2012222113A priority patent/AU2012222113B2/en
Priority to EP12749152.0A priority patent/EP2678070B1/en
Priority to CA2828293A priority patent/CA2828293C/en
Publication of WO2012116336A2 publication Critical patent/WO2012116336A2/en
Anticipated expiration legal-status Critical
Publication of WO2012116336A3 publication Critical patent/WO2012116336A3/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14557—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases specially adapted to extracorporeal circuits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552—Details of sensors specially adapted therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • A61M1/361—Physical characteristics of the blood, e.g. haematocrit, urea before treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3607—Regulation parameters
    • A61M1/3609—Physical characteristics of the blood, e.g. haematocrit, urea
    • A61M1/3612—Physical characteristics of the blood, e.g. haematocrit, urea after treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/367—Circuit parts not covered by the preceding subgroups of group A61M1/3621
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/84—Systems specially adapted for particular applications
    • G01N21/85—Investigating moving fluids or granular solids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/02042—Determining blood loss or bleeding, e.g. during a surgical procedure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/026—Measuring blood flow
    • A61B5/029—Measuring blood output from the heart, e.g. minute volume
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3306—Optical measuring means
    • A61M2205/3313—Optical measuring means used specific wavelengths
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow
    • A61M2205/3334—Measuring or controlling the flow rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/205—Blood composition characteristics partial oxygen pressure (P-O2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/20—Blood composition characteristics
    • A61M2230/207—Blood composition characteristics hematocrit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3577—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/064—Stray light conditioning
    • G01N2201/0646—Light seals

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Pathology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • External Artificial Organs (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

An optical blood monitoring system blocks unwanted light from sensors in a sensor clip assembly fastened to a blood chamber connected in an extracorporeal blood treatment system. The blood chamber has an internal flow cavity for communicating the extracorporeal blood flow and viewing windows to enable the sensor clip assembly to illuminate the blood with light as blood flows through the blood chamber in order to monitor blood characteristics. The sensor clip assembly includes opposing heads with LED emitters and photodetectors. Lenses in the heads may be surrounded by shrouds extending from the lenses so that when the sensor clip assembly is fastened to the blood chamber, shrouds block unwanted light from reaching the photodetectors. The blood chamber includes an opaque portion or a portion colored to attenuate particular wavelengths of light to enhance the blood chamber and sensor clip assembly's ability to block unwanted light from reaching the photodetectors.
PCT/US2012/026637 2011-02-25 2012-02-24 Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system Ceased WO2012116336A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CN201280010099.2A CN103796709B (en) 2011-02-25 2012-02-24 Optical blood monitoring system have cover sensor clip assembly and blood chamber
MX2013009761A MX2013009761A (en) 2011-02-25 2012-02-24 Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system.
JP2013555623A JP5940099B2 (en) 2011-02-25 2012-02-24 Shroud-covered sensor clip assembly and blood chamber for optical blood monitoring systems
AU2012222113A AU2012222113B2 (en) 2011-02-25 2012-02-24 Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system
EP12749152.0A EP2678070B1 (en) 2011-02-25 2012-02-24 Optical blood monitoring system with a shrouded sensor clip assembly and a blood chamber
CA2828293A CA2828293C (en) 2011-02-25 2012-02-24 Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US13/034,788 US8517968B2 (en) 2011-02-25 2011-02-25 Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system
US13/034,788 2011-02-25
US201161553078P 2011-10-28 2011-10-28
US61/553,078 2011-10-28

Publications (2)

Publication Number Publication Date
WO2012116336A2 WO2012116336A2 (en) 2012-08-30
WO2012116336A3 true WO2012116336A3 (en) 2014-02-27

Family

ID=46721488

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/026637 Ceased WO2012116336A2 (en) 2011-02-25 2012-02-24 Shrouded sensor clip assembly and blood chamber for an optical blood monitoring system

Country Status (7)

Country Link
EP (1) EP2678070B1 (en)
JP (1) JP5940099B2 (en)
CN (1) CN103796709B (en)
AU (1) AU2012222113B2 (en)
CA (1) CA2828293C (en)
MX (1) MX2013009761A (en)
WO (1) WO2012116336A2 (en)

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US10525182B2 (en) 2014-10-10 2020-01-07 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10898635B2 (en) 2016-07-18 2021-01-26 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US11865243B2 (en) 2016-08-30 2024-01-09 Nxstage Medical, Inc. Parameter monitoring in medical treatment systems
US12214114B2 (en) 2019-05-23 2025-02-04 Nxstage Medical, Inc. Flow synchronization devices, methods, and systems

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ES2641380T3 (en) 2012-12-14 2017-11-08 Gambro Lundia Ab Repositioning diaphragm for pressure capsule using position detection
DE102013103336A1 (en) 2013-04-03 2014-10-09 B. Braun Avitum Ag Device for identifying a dialyzer device or a component thereof, and sensor device usable therefor
JP6141733B2 (en) * 2013-09-20 2017-06-07 テルモ株式会社 Blood circulation device
US11090422B2 (en) 2015-05-13 2021-08-17 MAQUET CARDIOPULMONARY GmbH Equipment docking interface with latch mechanism for heart-lung machine
CN107683109B (en) * 2015-06-25 2021-06-08 费森尤斯医疗控股股份有限公司 Direct Optical Differential Measurement System
RU2730366C2 (en) * 2016-02-04 2020-08-21 Нова Биомедикэл Корпорэйшн Analytical system and method for determining hemoglobin parameters in whole blood
EP3509663B1 (en) * 2016-09-06 2024-07-03 Fresenius Kabi Deutschland GmbH Automated method and device for leukocyte collection from whole blood
US10576196B2 (en) * 2017-04-10 2020-03-03 Fresenius Medical Care Holdings, Inc. Optical detection of air bubbles in either saline or blood or a mixture of both
WO2019173283A1 (en) 2018-03-05 2019-09-12 Marquette University Method and apparatus for non-invasive hemoglobin level prediction
US20200049288A1 (en) * 2018-08-13 2020-02-13 Invetech, Inc. Functionalized Unitary Molded Manifolds For Closed Fluid Handling Systems
JP7298244B2 (en) * 2019-03-28 2023-06-27 株式会社ジェイ・エム・エス Sensor clip and liquid component measuring device
US11596723B2 (en) 2019-12-30 2023-03-07 Fresenius Medical Care Holdings, Inc. Intradialytic monitoring of blood volume change
CN113984663A (en) * 2021-10-28 2022-01-28 中国人民解放军海军特色医学中心 Optical detection device and working method thereof
CN119950858B (en) * 2025-03-27 2025-11-25 健帆生物科技集团股份有限公司 Bilirubin absorber and bilirubin concentration detection method

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Cited By (13)

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Publication number Priority date Publication date Assignee Title
US11406744B2 (en) 2014-10-10 2022-08-09 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10835658B2 (en) 2014-10-10 2020-11-17 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10835659B2 (en) 2014-10-10 2020-11-17 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10835657B2 (en) 2014-10-10 2020-11-17 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10869958B2 (en) 2014-10-10 2020-12-22 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10525182B2 (en) 2014-10-10 2020-01-07 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US11850341B2 (en) 2014-10-10 2023-12-26 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US12226557B2 (en) 2014-10-10 2025-02-18 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US10898635B2 (en) 2016-07-18 2021-01-26 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US11607482B2 (en) 2016-07-18 2023-03-21 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US12357736B2 (en) 2016-07-18 2025-07-15 Nxstage Medical, Inc. Flow balancing devices, methods, and systems
US11865243B2 (en) 2016-08-30 2024-01-09 Nxstage Medical, Inc. Parameter monitoring in medical treatment systems
US12214114B2 (en) 2019-05-23 2025-02-04 Nxstage Medical, Inc. Flow synchronization devices, methods, and systems

Also Published As

Publication number Publication date
JP2014513584A (en) 2014-06-05
EP2678070A2 (en) 2014-01-01
EP2678070B1 (en) 2022-10-19
JP5940099B2 (en) 2016-06-29
CN103796709A (en) 2014-05-14
AU2012222113B2 (en) 2015-09-24
CN103796709B (en) 2016-10-19
AU2012222113A1 (en) 2013-08-15
CA2828293A1 (en) 2012-08-30
CA2828293C (en) 2017-10-24
MX2013009761A (en) 2013-10-01
EP2678070A4 (en) 2018-03-28
WO2012116336A2 (en) 2012-08-30

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